Clinical trials: Pregnancy and PTSD
Depression, Postpartum, Depression
Interpersonal Treatment Program to Prevent Depression and Post-Traumatic Stress Disorder in Low-Income Pregnant Women With Partner Abuse
This study will evaluate the effectiveness of an interpersonally oriented treatment program called Reach Out for a Safe Environment in preventing depression and post-traumatic stress disorder in low-income pregnant women who have…
- Trial name
- NCT00602732
- Testing
- The Reach Out for a Safe Environment (ROSE) program, Enhanced care as usual (ECU)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Post-traumatic Stress Disorder, Miscarriage
Improving Mental Health Following Early PREgnancy Loss Using a Brief Cognitive Task
This is a randomised controlled trial designed to investigate the impact of a brief-cognitive task based intervention on intrusive memories, mental health symptoms and daily functioning, in women following an early pregnancy loss.
- Conditions
- Post-traumatic Stress Disorder, Miscarriage, Ectopic Pregnancy, Pregnancy Loss
- Trial name
- IMPREL (NCT05039853)
- Testing
- Brief cognitive task-based intervention
- Where
- United Kingdom
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Posttraumatic Stress Disorder, Pregnancy Related
Online Intervention to Promote Resilience to Traumatic Stress During Pregnancy
The investigators will design, construct, and pilot a prototype of a trauma-informed online intervention, which will be called "SunnysideFlex," that functionally integrates a web-based intervention targeting skills to decrease…
- Trial name
- NCT04992767
- Testing
- Sunnyside, SunnysideFlex
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Uterine Cervical Neoplasms
Post-TRaUmatic STress Disorder Induced by Gynecological Brachytherapy
This is a multicenter, prospective study aimed at providing information on the psychological effects (including post-traumatic stress symptoms) of utero-vaginal brachytherapy in patients with cervical cancer using…
- Trial name
- TRUST-GB (NCT07204535)
- Testing
- Prospective questionnaires
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Paul Strauss
PTSD (Childbirth-Related)
Preventing Childbirth-Related PTSD With Expressive Writing
The goal of this clinical trial is to test a brief psychological intervention given to individuals in the first days following childbirth who have experienced a potentially stressful childbirth.
- Trial name
- CARES (NCT05662423)
- Testing
- Expressive Writing about Childbirth, Neutral Writing
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depressive; Episode, Major, Depression, Postpartum
Diagnostic Accuracy of the Stepped Screening Protocol and Its Screening Tools in the Perinatal Period.
It is known that 1 in 5 women experience psychological difficulties during their pregnancy or in the first year after giving birth.
- Conditions
- Depressive; Episode, Major, Depression, Postpartum, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- DAS (NCT05961306)
- Testing
- SCID 5
- Where
- 2 sites in Belgium
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Ectopic Pregnancy
Posttraumatic Stress Disorder in Ectopic Pregnancy
The objective of the study is to prospectively assess the prevalence of post-traumatic stress disorder (PTSD) symptoms in a population of women who have experienced a diagnosis of ectopic pregnancy.
- Trial name
- NCT07306689
- Testing
- Impact of Event Scale - Revised (IES-R) questionnaire, Posttraumatic Stress Disorder Checklist - Specific (PCL-S) questionnaire, Trauma Recovery Measure (TRM) questionnaire
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
COVID-19, Pregnancy Complications
Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic
The purpose of this study is to assess the health and wellbeing of pregnant and recently pregnant women during the COVID-19 pandemic using an online survey.
- Conditions
- COVID-19, Pregnancy Complications, Mental Health Wellness 1, Anxiety
- Trial name
- NCT04385238
- Testing
- This is an online survey with no intervention.
- Where
- United States
- Volunteers
- 6,894 people
- Sponsor
- Pregistry
Mental Health, Physical Health
Parental Well-being After Childbirth in Switzerland
Improving maternal and child health is a global priority, with increasing emphasis on ensuring women and their families not only survive but also thrive after childbirth.
- Conditions
- Mental Health, Physical Health, Postpartum, Parents
- Trial name
- SOCRATES (NCT06886841)
- Where
- 2 sites in Switzerland
- Volunteers
- 4,200 people
- Sponsor
- Laurent Gaucher
PTSD
Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study
The majority of women with perinatal posttraumatic stress disorder (PTSD) do not receive mental health treatment despite the documented associations between PTSD and adverse pregnancy outcomes; this is likely due to workforce…
- Trial name
- TAPS (NCT05486793)
- Testing
- Written Exposure Therapy (WET), Emotion Focused Supportive Therapy (EFST)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Boston University
Abortion, Stillbirth
Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation
People seeking second-trimester dilation and evacuation (D\&E) procedures are often facing profoundly challenging circumstances, including desired pregnancies complicated by fetal anomalies or demise, serious maternal health…
- Conditions
- Abortion, Stillbirth, PTSD (Childbirth-Related), Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT07537894
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg
- Where
- United States
- Sponsor
- Stanford University
Posttraumatic Stress Disorder
Meeting the Needs of Pregnant Women With PTSD in Prenatal Care
The objectives of this research study are to screen 750 pregnant women at risk of trauma-related stress symptoms, and adapt and test an evidence-based intervention for pregnant women with PTSD and sub-threshold PTSD symptoms…
- Trial name
- NCT02807662
- Testing
- Adapted Seeking Safety Intervention
- Volunteers
- 149 people
- Sponsor
- University of Massachusetts, Worcester
Post-traumatic Stress Disorder, Stress Disorders
Effectiveness of Cognitive Processing Therapy in Pregnant Women With a History of Pregnancy Loss/Complication
The purpose of this study is to examine the effects of experiencing a previous pregnancy loss or complication on current physiological and emotional aspects of a current pregnancy.
- Conditions
- Post-traumatic Stress Disorder, Stress Disorders, Anxiety, Depression
- Trial name
- NCT01277354
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Postpartum Period, Depression
Relationship Between Postpartum Mood Disorders and Delivery Experience
The purpose of this study is to evaluate potential risk factors for developing postpartum depression or posttraumatic stress disorder during the first year postpartum in patients who have no preexisting history of PTSD or PPD.
- Conditions
- Postpartum Period, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NCT03004872
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Michigan
PTSD - Post Traumatic Stress Disorder, PTSD (Childbirth-Related)
The New Empowerment After eXposure to Trauma (NEXT) Study
The NEXT Study is a randomized controlled pilot examining the feasibility and acceptability of a revised perinatal PTSD protocol.
- Trial name
- NEXT (NCT07175025)
- Testing
- Narrative Exposure Therapy (NET)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Indiana University
Pregnancy Early, PTSD
PTSD Screening in Pregnant Black Women
This study will compare the effectiveness of two active screening interventions in improving post-traumatic stress disorder (PTSD) symptoms, maternal perinatal care utilization, satisfaction utilization of mental healthcare…
- Trial name
- NCT06522022
- Testing
- Culturally Responsive SBIRT for OB, Brief Screening for PTSD
- Where
- 2 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Emory University
Perinatal Mental Health, Reproductive Behavior
Women's Reproductive Choices and Mental Health During Pregnancy and After Birth in Wartime Ukraine
The goal of this observational study is to learn how war affects reproductive decisions and perinatal mental health in Ukrainian women.
- Conditions
- Perinatal Mental Health, Reproductive Behavior, Women, Cohort Studies
- Trial name
- NCT07551934
- Testing
- Psychological Assessment, Routine Clinical Data Collection
- Where
- Ukraine
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Taras Shevchenko National University of Kyiv
Childbirth-related PTSD, PTSD
International Survey of Childbirth-Related Trauma - Swedish Part
The goal of this cross-sectional observational study is to analyze childbirth-related PTSD, traumatic birth experiences and stress symptoms postpartum.
- Conditions
- Childbirth-related PTSD, PTSD, Postnatal Depression, Fear of Childbirth
- Trial name
- SwIntersect (NCT06207916)
- Where
- Sweden
- Volunteers
- 619 people
- Sponsor
- Region Östergötland
Post Traumatic Stress Disorder, Cardiovascular Diseases
NightWare and Cardiovascular Health in Women With PTSD
The purpose of this study is to determine whether NightWare therapeutic intervention improves biomarkers of vascular and renal function in premenopausal women with PTSD-related nightmares, and examine whether these improvements…
- Conditions
- Post Traumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness
- Trial name
- NCT07021014
- Testing
- NightWare
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Ectopic Pregnancy
Psychatric Effect of Ectopic Pregnancy
Assessment of anxiety,depressive symptoms and post traumatic stress after ectopic pregnancy Determine factors associated with development of anxiety,depressive symptoms and post-traumatic stress after ectopic pregnancy
- Trial name
- NCT06721403
- Volunteers
- 85 people
- Sponsor
- Assiut University