Clinical trials: Pregnancy in Diabetes
Hereditary Blood Disorders, Cardiovascular Diseases
Effect of mHealth Intervention on Oral Health-Related Quality of Life Among Adult Patients With Chronic Systemic Diseases
This study evaluated whether an mHealth oral health education intervention could improve oral health-related quality of life among adults with chronic systemic diseases registered in specialized disease centers in Al-Ahsa, Saudi…
- Conditions
- Hereditary Blood Disorders, Cardiovascular Diseases, Chronic Kidney Disease, Diabete Mellitus
- Trial name
- NCT07839429
- Testing
- mHealth Oral Health Education Intervention, Printed Oral Health Education Leaflet
- Where
- 4 sites in Saudi Arabia
- Volunteers
- 206 people
- Sponsor
- King Faisal University
Type 2 Diabetes Mellitus, Diabetic Kidney Disease
Low Carbohydrate Diet in Diabetic Kidney Disease
The current population of type 2 diabetes mellitus (T2DM) worldwide is over 200 million and Malaysia contributes to 1.2% of that number.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Kidney Disease, Obesity
- Trial name
- NCT04931030
- Testing
- Dietary advice
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Teknologi Mara
Gestational Diabetes, Continuous Glucose Monitoring
The Effect of Continuous Glucose Monitoring on Glycemic Control and Pregnancy Outcomes in Gestational Diabetes Mellitus
The purpose of this study is to determine if Continuous glucose monitoring improves glycemic control and pregnancy outcomes of Gestational Diabetes Mellitus
- Trial name
- NCT03955107
- Testing
- Continuous Glucose Monitoring System
- Where
- China
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Post Term Pregnancy, Premature Rupture of Membrane
Dilapan-S®: A Multicenter US E-registry
Objective of this registry is to collect a representative set of real world data on the use of Dilapan-S® for pre-induction cervical ripening in daily clinical practice.
- Conditions
- Post Term Pregnancy, Premature Rupture of Membrane, Fetal Growth Retardation, Oligohydramnios
- Trial name
- NCT04451109
- Testing
- Dilapan-S
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Medicem Technology s.r.o.
Type 2 Diabetes
Nutraceutical Citrulline in Pregnancy
The purpose of this study is to determine if oral of L-citrulline (3 grams/day) for 3 weeks provided in mid-pregnancy to pregnant women with type 2 diabetes will increase the plasma L-arginine/ADMA ratio, lower maternal blood…
- Trial name
- NCT02772887
- Testing
- L-Citrulline
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pittsburgh
Gestational Diabetes, Pregestational Diabetes
Possible Epigenetic Changes in Offspring of Women With Pregestational and Gestational Diabetes
Pregestational diabetes (PGD) during pregnancy may be associated with an increased rate of spontaneous abortions, intrauterine death and congenital anomalies among the offspring.
- Conditions
- Gestational Diabetes, Pregestational Diabetes, IDM (Infant of Diabetic Mothers), Neurodevelopmental Outcome
- Trial name
- NCT01255384
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Diabetic Kidney Disease (DKD)
ALLOPURINOL AND LISINOPRIL FOR DIABETIC KIDNEY PROTECTION: A COMPARATIVE STUDY IN NORMOURICEMIC TYPE 2 DIABETICS
This randomized controlled trial was conducted at the Department of Medicine and Diabetes of Mayo Hospital/King Edward Medical University, Lahore, over one year.
- Trial name
- NCT07177898
- Testing
- Allopurinol
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Narowal Medical College
Gestational Diabetes Mellitus in Pregnancy, Hyperprolactinemia Pregnancy
Prolactin and FGF21 in Gestational Diabetes Mellitus
Prolactin (PRL) and PRL receptor (PRLR) signaling has been validated to play an important role in the modulation of glucolipid metabolism.
- Trial name
- NCT05528393
- Testing
- Blood sampling
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shen Qu
Diabetes
Lifestyle Intervention in Overweight and Obese Pregnant Hispanic Women
The overall goal of this randomized controlled trial is to test the efficacy of a culturally and linguistically modified, individually tailored lifestyle intervention to reduce excess gestational weight gain (GWG), increase…
- Trial name
- NCT01868230
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Fetal Growth Restriction, Gut Microbiota
Gut Microbiota, SCFAs and Glucolipid Metabolism in Pregnant Women With Abnormal Fetal Size and Their Newborns
Abnormal fetal size includes fetal growth restriction and fetal macrosomia. Onset is closely related to maternal nutrition metabolism.
- Conditions
- Fetal Growth Restriction, Gut Microbiota, Fetal Macrosomia, Glucolipid Metabolism
- Trial name
- NCT04399434
- Testing
- test gut microbiota, SCFAs and glucolipid metabolism and insulin sensitivity
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Gestational Diabetes Mellitus in Pregnancy, Vitamin D Deficiency
Effects of Vitamin D Supplementation on Glucose Metabolism in Women With Former Gestational Diabetes Mellitus
Gestational Diabetes Mellitus (GDM) and vitamin D deficiency are related to insulin resistance and impaired beta-cell function, with heightened risk for future development of diabetes.
- Trial name
- NCT01992133
- Testing
- Vitamin D3
- Where
- Malaysia
- Volunteers
- 26 people
- Sponsor
- RCSI & UCD Malaysia Campus
Chronic Kidney Disease, Type 2 Diabetes
Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)
The goal of this clinical trial is to learn if starting four kidney disease medicines quickly and together (a rapid treatment approach) is safe and works well in people with type 2 diabetes and chronic kidney disease.
- Trial name
- RAPID-CKD (NCT07547878)
- Testing
- Finerenone, Semaglutide, Lotensin
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Baylor Research Institute
Diabetes Mellitus, Type 2, Gestational Diabetes
Community Health Worker-Led Postpartum Diabetes Screening
Women who experience gestational diabetes are at high risk of developing type 2 diabetes mellitus in the postpartum period-especially in low- and middle-income countries like India where the burden of diabetes is high and…
- Trial name
- NCT06209411
- Testing
- Home Based Testing, Clinic Based Screening, Food order nutritional intervention before meals
- Where
- India
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Hypercholesterolemia, Diabetes Insipidus
Effect of Statin Treatment on Urinary AQP2 (uAQP2/01)
The purpose of this study is to test the hypothesis that the function and/or regulation of urinary aquaporin 2 in hypercholesterolemic humans is affected by standard statin therapy, as compared with diet alone
- Trial name
- uAQP2/01 (NCT02523001)
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- University of Bari
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome
Among adult individuals with type 2 diabetes mellitus and at risk for heart failure with impaired relaxation of the heart mildly reduced kidney filtration function (Type 4 cardiorenal syndrome) this trial will evaluate the…
- Conditions
- Type 2 Diabetes Mellitus, Chronic Kidney Disease, Left Ventricular Diastolic Dysfunction
- Trial name
- NCT02251431
- Testing
- BYDUREON
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Baylor Research Institute
Diabetic Nephropathy
Open Label Tolerability and Safety Study of KRX-101 in Australia, New Zealand, and Hong Kong
The purpose of this study is to assess the tolerability and safety of KRX-101 in treating persistent microalbuminuria in type 2 diabetic patients who are also being treated with stable, maximum tolerated doses of either ACE…
- Trial name
- NCT00462202
- Testing
- sulodexide
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Keryx Biopharmaceuticals
Preeclampsia, Gestational Hypertension
Serum Vasohibin, Cardiotrophin, Endocan & Perinatal Outcomes
Investigation of the relationship between maternal serum vasohibin-1, vasohibin-2, cardiotrophin -1 and endocan concentrations at the 11th and 14th weeks of gestation and adverse perinatal outcomes.
- Conditions
- Preeclampsia, Gestational Hypertension, Gestational Diabetes, Preterm Birth
- Trial name
- NCT06416995
- Testing
- first trimester serum diagnostic test
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Umraniye Education and Research Hospital
Gestational Diabetes, Pregnancy Related
Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes
The aim of our study is to compare neonatal and maternal outcomes using different thresholds for the initiation and titration of pharmacotherapy for gestational diabetes (GDM).
- Trial name
- START 1 (NCT06419777)
- Testing
- Insulin
- Where
- 2 sites in United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Diabetic Nephropathy
To Determine the Effects of Avosentan on Doubling of Serum Creatinine, End Stage Renal Disease and Death in Diabetic Nephropathy
The purpose of this study is to determine whether avosentan (SPP301) is effective in decreasing morbidity and mortality in patients with diabetic nephropathy.
- Trial name
- NCT00120328
- Testing
- SPP301
- Where
- United States
- Volunteers
- 2,364 people
- Sponsor
- Speedel Pharma Ltd.
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