Clinical trials: Pregnancy in Diabetic
Diabetic Kidney Disease, Obesity
Metabolic Phenotypes of Obesity and Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus
1. Comparison between the 4 groups of metabolic phenotypes of obesity as regard the presence and frequency of DKD 2. Relation between DKD , obesity (BMI) and metabolic risk factors in patients with type 2 DM
- Conditions
- Diabetic Kidney Disease, Obesity, Metabolic Syndrome, Diabetes Mellitus, Type 2
- Trial name
- NCT06591104
- Testing
- 24 hour urinary protein
- Volunteers
- 71 people
- Sponsor
- Assiut University
Diabetic Nephropathy
Safety, Tolerability, and Pharmacokinetics (PK) of CTP-499
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of CTP-499 following single dose administration.
- Trial name
- NCT01328821
- Testing
- CTP-499
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Concert Pharmaceuticals
Urinary Incontinence, Bladder Dysfunction
Neuropathic Investigation and Anticholinergic Treatment of Bladder Dysfunction in Diabetes and Stroke Patients
Develop and quantify methods for evaluating bladder dysfunction in diabetes and stroke
- Trial name
- NCT00713921
- Testing
- Fesoterodine Oral Product
- Where
- United States
- Sponsor
- Saint Thomas Health
Type2 Diabetes
Renal Actions of Combined Empagliflozin and LINagliptin in Type 2 diabetES
The current study aims to explore the clinical effects and mechanistics of mono- and combination therapy with SGLT-2 inhibitor empagliflozin and DPP-4 inhibitor linagliptin on renal physiology and biomarkers in metformin-treated…
- Trial name
- RACELINES (NCT03433248)
- Testing
- EMPA/LINA 10/5 mg QD (n=22), LINA/EMPA 5/10 mg QD (N=22), Gliclazide 30 mg QD/BID (N=22)
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- M.H.H. Kramer
Diabetes During Pregnancy, Gestational Diabetes
Managing Diabetes in Pregnancy Using Cell Phone/Internet Technology
To compare compliance and satisfaction between a traditional method of blood glucose reporting using voicemail (control) and a novel method using cell phone /internet (Confidant) technology in the management of diabetic pregnant…
- Trial name
- NCT01907516
- Testing
- Cell phone-internet home glucose reporting system, Voicemail home blood glucose reporting
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hawaii Pacific Health
Diabetic Nephropathy, Type 2 Diabetes Mellitus
A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Diabetic Nephropathy
The purpose of this study is to evaluate the safety and efficacy of treatment with CCX140-B in subjects with diabetic nephropathy.
- Trial name
- NCT01447147
- Testing
- CCX140-B
- Where
- 83 sites in Belgium, Czechia and 4 more
- Volunteers
- 332 people
- Sponsor
- Amgen
Diabetic Peripheral Neuropathy
Combined Effects of INF and OEP in Patients With Diabetic Peripheral Neuropathy
DPN often leads to balance issues, sensory deficits, and chronic pain, which can severely impact daily functioning and independence.
- Trial name
- NCT07274735
- Testing
- Intraneural facilitation therapy, Otago exercise program, Intraneural facilitation therapy with Otago exercise program
- Where
- Pakistan
- Volunteers
- 65 people
- Sponsor
- Riphah International University
Diabetic Nephropathy, Medication Compliance
Effect of Low GI/ Glycemic Load (GL) Diet in Diabetic Nephropathy Patients
low GI and low GL diet have more beneficial effect for diabetic nephropath patients compared with conventional diet. low GL may have more favorable effect than low GI diet.
- Trial name
- NCT02384902
- Testing
- low GI, conventional diet
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Isfahan University of Medical Sciences
Diabetic Kidney Disease
Treatment of Patients With Diabetic Kidney Disease
Due to irrespective of the limitations associated with estimated glomerular filtration rate (eGFR), it is crucial to develop new treatments that can effectively address these concerns.
- Trial name
- NCT06187493
- Testing
- lisinopril, enalapril, dapagliflozin, empagliflozin
- Volunteers
- 70 people
- Sponsor
- Assiut University
Diabetic Nephropathy Type 2, Albuminuria
Dietary Interventions on Glycocalyx Dimensions in South Asian Patients With Diabetic Nephropathy.
Evaluate the effect of a fasting mimicking diet and a food supplement on the microvascular health and urinary heparanase levels in South Asian type 2 diabetic patients with albuminuria.
- Conditions
- Diabetic Nephropathy Type 2, Albuminuria, Type2 Diabetes Mellitus, Glucose Metabolism Disorders
- Trial name
- Glycotreat (NCT03889236)
- Testing
- Fasting mimicking diet Prolon, Food supplement Endocalyx
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Leiden University Medical Center
Cystic Fibrosis
Pregnancies and Cystic Fibrosis
There have been substantial advances in care for individuals with CF, including improved nutrition and respiratory care. Women with CF are now likely to survive into adulthood with a median predicted survival of 49.7 years in…
- Trial name
- MUCOG (NCT03290144)
- Volunteers
- 450 people
- Sponsor
- Hospices Civils de Lyon
Type 2 Diabetes
Metformin in Women With Type 2 Diabetes in Pregnancy Trial
Insulin is the standard treatment for the management of type 2 diabetes in pregnancy, however despite treatment with insulin, these women continue to face increased rates of adverse maternal and fetal outcomes.
- Trial name
- MiTy (NCT01353391)
- Testing
- Metformin
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Mount Sinai Hospital, Canada
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Treatment Satisfaction and Treatment Adherence of Diabetic Women Through the Use of FGM
The incidence of gestational diabetes mellitus (GDM), a glucose tolerance disorder during pregnancy, is increasing. In Germany, it reached 8.58 % in 2019. Standardized treatment has reduced complications for mother and child.
- Trial name
- Flash (NCT05924724)
- Testing
- Flash Glucose Monitoring
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Jena University Hospital
Diabetic Nephropathy Type 2 - Uncontrolled, Diabetes Mellitus, Type 2
Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus
The overarching goal of this study is to understand facilitators and barriers to self-care, develop and refine a culturally tailored intervention to improve clinical outcomes, quality of life (QOL), and self-care behaviors in…
- Conditions
- Diabetic Nephropathy Type 2 - Uncontrolled, Diabetes Mellitus, Type 2, Chronic Kidney Diseases
- Trial name
- NCT05692388
- Testing
- Patient and Community Stakeholder Interviews, Cross-sectional Study Participants, Focus Groups and Intervention Mapping
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Medical College of Wisconsin
Diabetic Pregnancy, Insulin Resistance
Metformin Use to Improve Pregnancy Outcome in Women With Type 1 Diabetes.
The study investigates whether additional metformin medication in combination with regular insulin treatment will decrease the need of insulin for women with diabetes mellitus type 1 during pregnancy.
- Conditions
- Diabetic Pregnancy, Insulin Resistance, Type1diabetes
- Trial name
- NCT03765359
- Testing
- metforminhydrochloride
- Where
- 5 sites in Finland
- Volunteers
- 101 people
- Sponsor
- Tampere University Hospital
Gestational Diabetes Mellitus in Pregnancy
Shear Wave Elastography in Gestational Diabetes Mellitus
Our aim was to investigate and compare placental elasticity by using Shear wave elastography (SWE) in patients with gestational diabetes mellitus (GDM) with and without insulin to non-diabetic controls.
- Trial name
- NCT04455880
- Testing
- SWE is a novel noninvasive dynamic ultrasound technique which refers to measurement for quantitative analysis of tissue elasticity
- Where
- Turkey (Türkiye)
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Gulsum Uysal
Diabetes Mellitus, Diabetic Nephropathy
The Effect of Green Tea or Cocoa Extracts in Endothelial Dysfunction in Patients With Diabetes Mellitus
The purpose of this study is to determine whether green tea or cocoa extracts are effective in improve endothelial dysfunction in patients with diabetes mellitus and nephropathy and arterial hypertension.
- Conditions
- Diabetes Mellitus, Diabetic Nephropathy, Arterial Hypertension
- Trial name
- NCT01130727
- Testing
- green tea extract, cocoa extract rich in polyphenols, low polyphenol cocoa extract
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- University of Campinas, Brazil
Proteinuria
Anti-proteinuric Effect of Calcitriol in Non-diabetic Kidney Disease Patients
Proteinuria is not only a marker of chronic kidney disease (CKD) progression, but also a marker of cardiovascular disease and death.
- Trial name
- NCT01512862
- Testing
- Calcitriol
- Where
- 3 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Seoul National University Hospital
Healthy
A Multiple Dose Study To Determine Safety, Tolerability, and Pharmacokinetics Of PF-04634817 In Healthy Adult Subjects
The goals of this study are to evaluate the safety and tolerability of multiple ascending doses of PF-04634817 administered orally to healthy adult subjects.
- Trial name
- NCT01140672
- Testing
- PF-04634817
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pfizer
Inflammation, Chronic Kidney Disease
Role of Prohepcidin in Uremic Patients
The investigators aimed to study the effect of prohepcidin levels on hematologic parameters and inflammatory markers in non-diabetic uremic patients.
- Trial name
- NCT01735773
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital