Clinical trials: Prehospital Emergency
Drowning, Drown
Drowning Incidents in Danish Harbours
A recent study reported significantly increased mortality from drowning-related out-of-hospital cardiac arrest in Danish harbours compared to other public places (e.g., public pools, coastlines, and lakes).
- Conditions
- Drowning, Drown, Drowning; Anoxia, Drowning, Near
- Trial name
- DROWN_HARBOR (NCT06312202)
- Testing
- Drowning
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Prehospital Center, Region Zealand
Anesthesia, Hypoxia
Assessment of Preoxygenation Strategies in the Prehospital Environment
Comparison of the preoxygenation efficacy of tidal volume breathing using three different preoxygenation techniques which are available to providers in the prehospital environment.
- Trial name
- NCT02694705
- Testing
- Continuous Positive Airway Pressure (CPAP), Bag-Valve-Mask (BVM), Non-rebreather Mask (NRM)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Trauma
SWiFT Canada (Study of Whole Blood in Frontline Trauma)
Traumatic injuries affect people of all ages, races, and socioeconomic backgrounds. The Global Burden of Disease study showed that globally in 2019, there were more than 4.4 million deaths due to injury.
- Trial name
- SWiFTCanada (NCT06495294)
- Testing
- Whole Blood, RBC + plasma
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Spontaneous Subarachnoid Hemorrhage
Time to Specialized Admission in Case of Severe Brain Haemorrhage.
Spontaneous subarachnoid haemorrhages (SAH) are a particularly severe type of stroke with a tendency to affect younger individuals than other types of stroke.
- Trial name
- NCT03786068
- Where
- Denmark
- Volunteers
- 262 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sepsis, Severe Sepsis
Prehospital Antibiotics Against Sepsis Trial
Sepsis is one of the most frequent reasons for referral to emergency departments (EDs) worldwide. The incidence of sepsis is likely to rise in the upcoming years.
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- PHANTASi (NCT01988428)
- Testing
- Ceftriaxone 2000 mg
- Where
- 34 sites in Netherlands
- Volunteers
- 2,672 people
- Sponsor
- Amsterdam UMC, location VUmc
Tracheal Intubation Morbidity, Prehospital Emergency
Impact of the Bougie on the Prehospital Setting Intubation Quality.
Tracheal intubation in an out-of-hospital setting is a frequent and potentially difficult procedure. The risk of adverse events increases dramatically with the number of attempts.
- Trial name
- SMURIDS2 (NCT05173220)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
Acute Hypoxemic Respiratory Failure, Acute Respiratory Distress Syndrome
EndotyPIng PreHospitAl de Novo Acute hYpoxemic Respiratory Failure
We attempt to perform dynamic endotyping of critically ill patients presenting in the emergency department with de novo acute hypoxemic respiratory failure (AHRF).
- Trial name
- EPIPHANY (NCT05150483)
- Where
- Greece
- Volunteers
- 350 people
- Sponsor
- Evangelismos Hospital
Immobilization
Time Performance of Scoop Stretcher Versus Vacuum Mattress for Prehospital Spinal Stabilization
A simulation-based randomized controlled trial was designed with the objective to assess the time needed to achieve spinal stabilization using a scoop stretcher compared to a vacuum mattress.
- Trial name
- NCT04904770
- Testing
- Scoop stretcher, Vacuum mattress
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Stuby Loric
eFast, Fate
Point-of-care Ultrasound Teledidactic Teaching for Prehospital Emergency Personnel
The goal of this clinical trial is to compare two methods of teaching emergency medical service (EMS) providers how to use point-of-care ultrasound (POCUS) to quickly assess critical conditions like internal bleedings.
- Conditions
- eFast, Fate, Education, Medical, Point of Care Ultrasound (POCUS)
- Trial name
- POCUS TT (NCT06824675)
- Testing
- Teledidactic Training, In-Person Hands-on Training
- Where
- Austria
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Trauma, Coagulopathy
Impact of a Prehospital Identification of Trauma Patients in Need for Damage Control Resuscitation.
Early identification of trauma patients in need for Damage Control Resuscitation (DCR) has potential to be beneficial for general emergency units that are not expected to be ready for this rare situation 24 hours per day, 7 days…
- Conditions
- Trauma, Coagulopathy, Hemorrhage, Emergencies
- Trial name
- NCT03444077
- Testing
- Use of the Trauma Induced Coagulopathy Clinical Score (TICCS) as a diagnostic tool., Regular care, STTTOPPP the bleeding
- Where
- 4 sites in Belgium
- Volunteers
- 400 people
- Sponsor
- University of Liege
Intubation, Intratracheal, Emergency Medicine
Prehospital and Emergency Feasibility of MACOCHA Score Assessment to Predict Difficult Tracheal Intubation
A seven-item simplified score (the MACOCHA score) has been validated to predict difficult tracheal intubation in intensive care unit patients.
- Trial name
- E-MAC (NCT03420027)
- Testing
- questionnaire to be filled in by investigators
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Cerebrovascular Accident
Field Administration of Stroke Therapy - Magnesium (FAST-MAG) Trial
The goal of this study is to evaluate the effectiveness and safety of field-initiated magnesium sulfate in improving the long-term functional outcome of patients with acute stroke.
- Trial name
- FAST-MAG (NCT00059332)
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- United States
- Volunteers
- 1,700 people
- Sponsor
- Jeffrey L. Saver
Stroke (CVA) or Transient Ischemic Attack
Predictive Value of Witness-derived Secondary Cincinnati Prehospital Stroke Scale Scores in Suspected Stroke
The Cincinnati Prehospital Stroke Scale (CPSS) is traditionally scored directly by a healthcare professional or a layperson who independently observes facial droop, arm weakness, and speech disturbance, constituting the primary…
- Trial name
- NCT07277790
- Where
- Turkey (Türkiye)
- Volunteers
- 235 people
- Sponsor
- Ankara City Hospital Bilkent
Echocardiography, Telemedicine
Live Stream of Prehospital point-of Care Ultrasound by Air Rescue Physicians
Background: Point-of-care ultrasound (POCUS) has been suggested as a useful tool in emergency medicine for diagnosis and treatment of reversible causes.
- Trial name
- NCT04810520
- Testing
- Point-of-care ultrasound with tele-supervision, Point-of-care ultrasound without tele-supervision
- Where
- Austria
- Sponsor
- Medical University of Vienna
Rhabdomyolysis, Virtual Reality
Evaluation of the Effectiveness of Using Virtual Reality Glasses in Prehospital Intervention Training for Crush Syndrome
This research is a randomized controlled study designed to develop and evaluate the effectiveness of a video-based virtual reality (VR) simulation for prehospital intervention training of crush syndrome for paramedic students.
- Conditions
- Rhabdomyolysis, Virtual Reality, Emergency Medical Services, Disaster Medicine
- Trial name
- NCT07361835
- Testing
- Virtual reality-based crush syndrome training, Traditional theoretical lecture
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Ege University
Intubation Complication, Intubation; Difficult or Failed
Prehospital Intubation of COVID-19 Patient With Personal Protective Equipment
The safety and efficacy of a laryngoscopy as a primary intubation tool in urgent endotracheal intubation of cardiac arrest patients with suspected/confirmed COVID-19 has not been well-described in the literature.
- Conditions
- Intubation Complication, Intubation; Difficult or Failed, Cardiac Arrest, Influenza
- Trial name
- NCT04365608
- Testing
- Direct laryngoscopy, Vie Scope laryngoscopy
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Lazarski University
Ultrasound
Live Stream of Ultrasound in Prehospital Medical Care
Prehospital emergency ultrasound (PEU) is being increasingly used in different preclinical emergency systems across the world. Ultrasound examinations in emergency situations, however, remain challenging even in the hospital…
- Trial name
- NCT04612816
- Testing
- Prehospital ultrasound
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Medical University of Vienna
Acute Respiratory Failure Requiring Intubation
Bougie Versus Endotracheal Tube Alone on First-attempt Intubation Success in Prehospital Emergency Intubation (BETA Trial)
Emergency intubation is routinely performed in the prehospital setting. Airway management in the prehospital setting has substantial challenges, such as hostile environment or lack of technical support in case of first attempt…
- Trial name
- BETA (NCT06307392)
- Testing
- First intubation attempt with endotracheal tube plus bougie, First intubation attempt with endotracheal tube alone
- Where
- 10 sites in France
- Volunteers
- 710 people
- Sponsor
- Nantes University Hospital
Critically Ill, Major Trauma
Brain Oxygenation During Prehospital Anesthesia: an Observational Study
Brain oxygenation of adult patients undergoing prehospital emergency anesthesia is monitored using noninvasive near-infrared spectroscopy.
- Conditions
- Critically Ill, Major Trauma, Anesthesia, Emergencies
- Trial name
- BOPRA (NCT04144803)
- Testing
- Cerebral near-infrared spectroscopy
- Where
- 6 sites in Finland
- Volunteers
- 1,300 people
- Sponsor
- Helsinki University Central Hospital
Traumatic Injuries, Prehospital Emergency Care
Study of Pre Hospital Management of Polytrauma Patients by Medical Teams From a Department in the Parisian Region
To study the impact of prehospital management duration by SMUR teams in the Essonne department (91) on early patient mortality (within 24 hours) and to analyze the procedures performed on scene.
- Conditions
- Traumatic Injuries, Prehospital Emergency Care, Early Mortality
- Trial name
- DELTA-91 (NCT07414186)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Sud Francilien