Clinical trials: Prehospital Emergency
Acute Hypoxemic Respiratory Failure, Acute Respiratory Distress Syndrome
EndotyPIng PreHospitAl de Novo Acute hYpoxemic Respiratory Failure
We attempt to perform dynamic endotyping of critically ill patients presenting in the emergency department with de novo acute hypoxemic respiratory failure (AHRF).
- Trial name
- EPIPHANY (NCT05150483)
- Where
- Greece
- Volunteers
- 350 people
- Sponsor
- Evangelismos Hospital
Prehospital Emergency, Teleconsultation
Operation of a Mobile Telemedicine System in the EMS
The aim of the study is to investigate the safety and efficacy of the operation of a prehospital teleconsultation system in the Emergency Medical Service.
- Conditions
- Prehospital Emergency, Teleconsultation, Safety
- Trial name
- NCT01647854
- Testing
- Teleconsultation
- Where
- Germany
- Volunteers
- 425 people
- Sponsor
- RWTH Aachen University
Stroke
Stroke Cincinnati Prehospital Stroke Severity Scale Evaluation iN prEhospital
The effectiveness of acute ischemic stroke (AIS) management has improved considerably in recent years with thrombolysis and more recently with mechanical thrombectomy (MT).
- Trial name
- SCENE (NCT03181412)
- Testing
- Questionnaire
- Where
- 12 sites in France
- Volunteers
- 1,272 people
- Sponsor
- Hospices Civils de Lyon
Analgesia, Prehospital
Quality of Telemedically Guided Prehospital Analgesia
The purpose of this retrospective study is to analyze quality and adverse events of analgesia by telemedically supported paramedics in comparison to conventional treatment by on-scene emergency medical service (EMS) physicians in…
- Conditions
- Analgesia, Prehospital, Telemedicine, Ambulance
- Trial name
- NCT02928705
- Testing
- physician operated telemedical prehospital analgesia, prehospital analgesia by on-scene EMS physicians
- Where
- Germany
- Volunteers
- 381 people
- Sponsor
- RWTH Aachen University
Dyspnea
Evaluation of the Impact of Pleuropulmonary Ultrasound on the Diagnosis of Dyspnea
Dyspnea is a subjective symptom perceived by the patient as a sensation of "breathing discomfort", "suffocation", "lack of air" or "difficulty inhaling or exhaling". It is a frequent reason for calling for help (8% of calls).
- Trial name
- LU-SMUR (NCT07104578)
- Testing
- Pleuropulmonary ultra sound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Stroke Acute, Emergency Medical Services
Sex diffErences in prehoSpitAl Stroke MEdicine
Background: Stroke is a leading cause for individual, family and societal harm with huge health-economic impact. Immediate and correct prehospital acute stroke pathway initiation is key for treatment success.
- Conditions
- Stroke Acute, Emergency Medical Services, Sex Characteristics, Prehospital Setting
- Trial name
- SESAME (NCT06865950)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Universität des Saarlandes
Agitation
Ketamine Versus Haloperidol for Severe Agitation Outside the Hospital
This research study is being done to find out if one of two drugs, ketamine or haloperidol, is better for treating agitation. Agitation is a state of extreme emotional disturbance where patients can become physically aggressive…
- Trial name
- NCT02103881
- Testing
- Ketamine, Haloperidol
- Sponsor
- Hennepin Healthcare Research Institute
Preoxygenation
Preoxygenation Before Prehospital Tracheal Intubation With NIV Versus Balloon
Recent studies reports feasibility, effectiveness and even less complications of using NIV for preoxygenation during tracheal intubation in ICU and in Operating Room.
- Trial name
- PREOXY (NCT01232153)
- Testing
- Non invasive ventilation
- Where
- France
- Sponsor
- Hopital of Melun
Tracheal Intubation Morbidity, Prehospital Emergency
Impact of the Bougie on the Prehospital Setting Intubation Quality.
Tracheal intubation in an out-of-hospital setting is a frequent and potentially difficult procedure. The risk of adverse events increases dramatically with the number of attempts.
- Trial name
- SMURIDS2 (NCT05173220)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
COPD Exacerbation, COPD Exacerbation Acute
Prehospital Non-invasive Ventilation for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The goal of this clinical trial is to test if treatment with prehospital Non-invasive ventilation (NIV) for patients with acute respiratory failure (ARF), due to acute exacerbation of chronic obstructive pulmonary disease…
- Conditions
- COPD Exacerbation, COPD Exacerbation Acute, Noninvasive Ventilation, Emergency Medical Services
- Trial name
- PRENIV (NCT06211920)
- Testing
- Non-invasive ventilation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Central Denmark Region
Intubation, Intratracheal, Emergency Medicine
Prehospital and Emergency Feasibility of MACOCHA Score Assessment to Predict Difficult Tracheal Intubation
A seven-item simplified score (the MACOCHA score) has been validated to predict difficult tracheal intubation in intensive care unit patients.
- Trial name
- E-MAC (NCT03420027)
- Testing
- questionnaire to be filled in by investigators
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Telemedicine, Triage
Mobile Transmission of Prehospital Vital Signs to the Emergency Department
The purpose of this study is to examine if real time transmission of vital signs, ECG and chat communication between the prehospital ambulances and the emergency department has an effect on patient mortality, ICU admission…
- Conditions
- Telemedicine, Triage, Emergency Medical Service
- Trial name
- NCT02090452
- Testing
- Real time transmission of patient related data. Device used: MobiMed 3.1, manufactured by Ortivus AB Sweden
- Where
- 3 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Spontaneous Subarachnoid Hemorrhage
Time to Specialized Admission in Case of Severe Brain Haemorrhage.
Spontaneous subarachnoid haemorrhages (SAH) are a particularly severe type of stroke with a tendency to affect younger individuals than other types of stroke.
- Trial name
- NCT03786068
- Where
- Denmark
- Volunteers
- 262 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Injuries, Pain
Randomized Double Blind Controlled Trial Comparing a Blind Sciatic Nerve Block in the Popliteal Fossa to Intravenous Morphine for Traumatic Severe Acute Pain in the Prehospital Setting
The purpose of the study is to determine the efficacity of a simple blind technic of loco regional anaesthesia of the sciatic nerve compared to the gold standard in emergency medecine : the intravenous morphine for treated the…
- Conditions
- Injuries, Pain, Emergencies
- Trial name
- BPOP (NCT01522534)
- Testing
- Mepivacaine, Morphine
- Where
- 6 sites in France
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Telemedicine, Emergency Medical Service
Audiovisual Consultations in Prehospital Emergency Care: Randomised Controlled Trial
This study investigates safety and efficacy of the use of audiovisual consultations of emergency medical service (EMS) doctor by paramedics for low urgency events in areas covered with paramedic crews only from emergency medical…
- Trial name
- Telemedicine (NCT04312321)
- Testing
- Mandatory phone call consultation, Mandatory audiovisual consultation
- Where
- Czechia
- Volunteers
- 600 people
- Sponsor
- Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O.
Telemedicine, Intubation; Difficult or Failed
Teleguidance-facilitated Airway Management
The advent of telemedicine has introduced teleguidance as a promising support to enhance endotracheal intubation skills among inexperienced operators.
- Conditions
- Telemedicine, Intubation; Difficult or Failed, Emergencies
- Trial name
- NCT06497725
- Testing
- Teleguidance-facilitated Airway Management
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Traumatic Brain Injury
Prehospital Severe Traumatic Brain Injury
The aim of the study is to measure the effect of Finnish physician-staffed EMS unit treatment methods on traumatic brain injury (TBI) patient prognosis.
- Trial name
- NCT02659046
- Where
- Finland
- Volunteers
- 266 people
- Sponsor
- Tampere University Hospital
Severe Traumatic Pain, Numeric Pain Rating Scale > 5 / 10
Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency Setting
Intranasal (IN) administration of opiates is an appealing non-invasive way of treating acute traumatic pain in prehospital and Emergency departments (ED).
- Trial name
- ALGOFINE-2 (NCT02095366)
- Testing
- Morphine, Sufentanil
- Where
- 6 sites in France
- Volunteers
- 194 people
- Sponsor
- University Hospital, Grenoble
Carbon Monoxide Poisoning
Role of Pulse Co-oximetry for Detecting Carbon Monoxide Poisoning in the Prehospital Emergency Medical Service Setting
The RAD-57 pulse CO-oximeter is a lightweight device allowing non-invasive measurement of blood carboxyhemoglobin. Previous studies comparing RAD-57 measurements (SpCO) to standard laboratory blood gas analysis (COHb) have…
- Trial name
- CO-OX (NCT02860455)
- Testing
- RAD57 measurement (SpCO), CO-oximeter
- Where
- France
- Volunteers
- 176 people
- Sponsor
- University Hospital, Montpellier
Out-Of-Hospital Cardiac Arrest
Automatic Ventilation in Prehospital Resuscitation on OHCA
The goal of this randomized controlled trial is to compare prehospital ventilation strategies in out-of-hospital cardiac arrest. The intervention group is automatic ventilation and the control group is manual ventilation.
- Trial name
- NCT06067204
- Testing
- Automatic ventilation, Manual ventilation
- Where
- Taiwan
- Volunteers
- 522 people
- Sponsor
- National Taiwan University Hospital