Clinical trials: Prehospital Emergency
Out-of-hospital Cardiac Arrest
Prehospital Resuscitation Intra Nasal Cooling Effectiveness Survival Study
Promising result of intra-arrest cooling on neurological intact survival in cardiac arrest patients has recently been published in the PRINCE-study in Circulation 2010.
- Trial name
- PRINCESS (NCT01400373)
- Testing
- Prehospital intra-nasal cooling with RhinoChill
- Where
- 2 sites in Belgium, Sweden
- Volunteers
- 700 people
- Sponsor
- Karolinska Institutet
Myocardial Ischemia, Myocardial Infarction
Prehospital Evaluation and Economic Analysis of Different Coronary Syndrome Treatment Strategies - PREDICT
Despite remarkable gains in treatment over the last decade short-term mortality for those who survive to hospital with AT-elevation acute myocardial infarction (STEMI) remains high (5%-10%).
- Trial name
- PREDICT (NCT00747656)
- Where
- 5 sites in Canada
- Volunteers
- 446 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Depression, Anxiety
Epidemiology of Depression, Anxiety, and Cognitive Impairment
Many older adults have undetected health problems and lack basic prevention measures. Failure to identify and treat these conditions can lead to unnecessary morbidity and mortality and a decreased quality of life.
- Conditions
- Depression, Anxiety, Cognitive Impairment
- Trial name
- NCT00717041
- Where
- United States
- Volunteers
- 1,206 people
- Sponsor
- University of Rochester
Syncope
Canadian Prehospital Syncope Risk Score (Prehospital CSRS)
Background: Syncope is defined as a sudden, brief loss of consciousness (LOC) followed by a rapid complete recovery. It accounts for 160,000 emergency department (ED) visits each year in Canada.
- Trial name
- NCT05560126
- Where
- Canada
- Volunteers
- 4,875 people
- Sponsor
- Venkatesh Thiruganasambandamoorthy
ARF Secondary to COPD Exacerbation, ARF Secondary to Cardiogenic Acute Pulmonary Oedema
HERMES STUDY: Study on the Feasibility and Efficiency of Noninvasive Positive-Pressure Ventilation (NPPV) in Prehospital Care
The purpose of this study is determine if NPPV can be performed in a pre-hospital setting very early after onset of dyspnea with a similar benefit in need of intubation and mortality as in previous study in hospital context and…
- Trial name
- NCT00375154
- Testing
- Noninvasive Positive-Pressure Ventilation (NPPV)
- Where
- 8 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Suicide Attempts
Epidemiology of Acute Self-poisoning in Emergency Services in France
Acute self poisoning is a leading cause of suicide attempts and leads to frequent emergency department visits. However, the exact epidemiology of acute self poisoning is not known.
- Trial name
- EpiTox (NCT02518386)
- Testing
- No intervention
- Volunteers
- 700 people
- Sponsor
- University Hospital, Grenoble
Heart Failure, COPD
Ultrasound in Acute Dyspnea in the Field
Acute heart failure is one of the main causes of acute respiratory distres in prehospital emergency setting. The early and correct diagnosis is important because the misdiagnosis can result in deleterious consequeance to…
- Conditions
- Heart Failure, COPD, Asthma
- Trial name
- NCT01235182
- Where
- Slovenia
- Volunteers
- 248 people
- Sponsor
- University Medical Centre Maribor
Drug Overdose
Bioavailability of a New Formulation of Nasal Naloxone for Prehospital Use
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. The annual death toll from overdose is about 250, twice the annual death toll from traffic accidents.
- Trial name
- NCT02158117
- Testing
- nasal naloxone
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
ST Elevation Myocardial Infarction, Cardiovascular Diseases
RUral dispaRities in prehospitAL STEMI
Rural Americans are more likely to be unhealthy, older, living in poverty, uninsured, and medically underserved. The CDC has made achieving health equity and improving cardiovascular health for rural Americans one of their…
- Trial name
- NCT04381260
- Testing
- No intervention, Interview, Survey
- Where
- United States
- Volunteers
- 473 people
- Sponsor
- Wake Forest University Health Sciences
Dyspnea, Heart Failure
Dyspnea and Biomarkers in a Prehospital Setting
In patients presenting with acute dyspnea in a pre-hospital setting, the early and correct diagnosis may present a significant clinical challenge.
- Conditions
- Dyspnea, Heart Failure, Asthma, COPD
- Trial name
- NCT00878475
- Where
- Slovenia
- Volunteers
- 546 people
- Sponsor
- Community Healthcare Center dr. Adolf Drolc Maribor (HCM)
Trauma, Craniocerebral Trauma
Early Versus Late Intubation Trial in Physician Manned Emergency Medical Services
This study looks at advanced airway management in critically ill or injured patients treated by physician manned emergency medical services, comparing early (on-scene) intubation to late (emergency department) intubation.
- Conditions
- Trauma, Craniocerebral Trauma, Intracerebral Hemorrhage, Seizures
- Trial name
- ELITE (NCT01730001)
- Testing
- Early Intubation, Late intubation
- Where
- 2 sites in Norway
- Sponsor
- Norwegian Air Ambulance Foundation
Dyspnea
Evaluation of the Impact of Pleuropulmonary Ultrasound on the Diagnosis of Dyspnea
Dyspnea is a subjective symptom perceived by the patient as a sensation of "breathing discomfort", "suffocation", "lack of air" or "difficulty inhaling or exhaling". It is a frequent reason for calling for help (8% of calls).
- Trial name
- LU-SMUR (NCT07104578)
- Testing
- Pleuropulmonary ultra sound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Stroke
Stroke Cincinnati Prehospital Stroke Severity Scale Evaluation iN prEhospital
The effectiveness of acute ischemic stroke (AIS) management has improved considerably in recent years with thrombolysis and more recently with mechanical thrombectomy (MT).
- Trial name
- SCENE (NCT03181412)
- Testing
- Questionnaire
- Where
- 12 sites in France
- Volunteers
- 1,272 people
- Sponsor
- Hospices Civils de Lyon
Prehospital Emergency Medical Services, Point-of-care Ultrasound
Ultrasound Applications for Emergency Medical Technicians in Taiwan
The goal of this prospective observational study is to develop and assess the core ultrasound applications for emergency medical technicians (EMTs) in Taiwan.
- Trial name
- NCT06950333
- Testing
- POCUS education curriculum
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Brain Injuries, Traumatic, Brain Injuries, Acute
Critical Hyperacute Assessment Research On Neurobiomarker Kinetics in Acute Brain Injury
Traumatic brain injury (TBI) and other conditions that reduce blood flow to the brain - such as cardiac arrest (CA) - are life-threatening medical emergencies.
- Conditions
- Brain Injuries, Traumatic, Brain Injuries, Acute, Hypoxia, Brain, Cardiac Arrest (CA)
- Trial name
- CHARON (NCT07782216)
- Where
- 4 sites in Hungary
- Volunteers
- 477 people
- Sponsor
- University of Pecs
Acute Stroke
Smartphone-App Based Prediction of Large Vessel Occlusion
The aim of this non-interventional study is to evaluate a German version of the triage stroke-score FAST-ED performed by ambulance service personnel in a pre-hospital setting using a smartphone app (Join-Triage, Allm).
- Trial name
- NCT04404504
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Essen
Emergency Medical Dispatch Centre, Video Streaming
Dispatch of Emergency Call Using Video Streaming Compared With Traditional Telephone Communication
In the Emergency Medical Dispatch Center, all EMS dispatchers were divided into one of two clusters with 11 EMS dispatchers in each cluster.
- Conditions
- Emergency Medical Dispatch Centre, Video Streaming, Emergency Call, Prehospital Emergency Medical Services
- Trial name
- CAM-VISION (NCT05742412)
- Testing
- Video streaming (smartphone camera), Telephone (telephone microphone)
- Where
- Denmark
- Volunteers
- 20,539 people
- Sponsor
- Central Denmark Region
Asthma, COPD
Prehospital Emergency Care of Obstructive Respiratory Emergencies With the Use of Teleconsultation
The aim of the study is to investigate the quality of prehospital emergency care in acute respiratory emergencies, when paramedics are supported telemedically by an EMS physician.
- Trial name
- NCT01644045
- Testing
- Teleconsultation
- Where
- Germany
- Volunteers
- 17 people
- Sponsor
- RWTH Aachen University
Trauma Injury, Pain
Sufentanil Used by Paramedics to Treat Pain in Acute Trauma
The new competence of paramedics to administer opioid analgesics in acute trauma patients without presence or phone-call consult with an emergency medical doctor will be assessed in this study.
- Trial name
- NCT04913402
- Testing
- Sufentanil administered by paramedics after the phone call consultation of medical doctor., Sufentanil administered by paramedics based on their competency, without consultation of medical doctor.
- Where
- Czechia
- Volunteers
- 158 people
- Sponsor
- Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O.
Preoxygenation
Preoxygenation Before Prehospital Tracheal Intubation With NIV Versus Balloon
Recent studies reports feasibility, effectiveness and even less complications of using NIV for preoxygenation during tracheal intubation in ICU and in Operating Room.
- Trial name
- PREOXY (NCT01232153)
- Testing
- Non invasive ventilation
- Where
- France
- Sponsor
- Hopital of Melun