Clinical trials: Premature
HIV Infection, Vaginal Atrophy
Accelerated Genital Tract Aging in HIV: Estradiol Clinical Trial
During menopause, there is a decrease in a hormone estrogen, which leads to aging of the vagina. Vaginal aging includes changes in the type and amount of healthy bacteria in the vagina, inflammation and a breakdown of natural…
- Conditions
- HIV Infection, Vaginal Atrophy, Menopause, Menopause Related Conditions
- Trial name
- NCT04079218
- Testing
- Estradiol Vaginal Insert
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kerry Murphy
Osteopenia of Prematurity
Comparison of Two Different Doses of Vitamin D in Preterm Infants
randomized clinical trial comparing two different doses of vitamin d supplementation in preterm infants
- Trial name
- NCT03889717
- Testing
- vitamin D
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sepsis, Neonatal
Comparison Between Split Septum and Mechanical Valve Needleless Connector in Preterm Babies
The goal of this clinical trial study is to compare the effectiveness between split septum and mechanical valve needleless connector in very preterm babies (or under 1500 grams) The main questions it aims to answer are: What is…
- Trial name
- NCT06414174
- Testing
- Split septum needleless connector, Mechanical valve needleless connector
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Preterm Birth
Microbiome And Multi'Omics In Preterm Birth: The Bacteria And Birth Study
Hominids and hominins serve as remarkable hosts to microbes, and we have co-evolved over the past 4.5 million years as highly plethoric communities.
- Trial name
- BaBs (NCT02392650)
- Where
- United States
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Preterm Birth
Human Milk in Preterm Infants
Current NICU protocol introduces human milk fortifier at 8 days of feeding. This study will introduce human milk fortifier at day 1. The primary outcome is the effect on growth velocity at 28 days and 36 weeks post menstrual age.
- Trial name
- NCT05228535
- Testing
- Human milk fortifier
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Augusta University
Prematurity
The Effect of Music on Preterm Infant's Brain Development
Studying the effect of music intervention on preterm infants' brain development by MRI and neurodevelopmental assessments
- Trial name
- NCT03689725
- Testing
- Music
- Where
- Switzerland
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Trace Aluminum Ions in Parenteral Nutrition
Portable Detection, Assessment, and Control of Trace Aluminum Ions in Parenteral Nutrition Formulations for Preterm Infants
The research team will develop a series of multivalent nanozyme materials (MOF@Arg@His) to construct a sensing platform with dual-mode colorimetric and fluorescent responses, thereby markedly improving the sensitivity and…
- Trial name
- PN-Al POCT (NCT07646925)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Han Tongyan
Very Premature Baby
Attention Control Training (ACT) and Very Preterm Infants
Infants' attention control, defined as the ability to select what to pay attention to, is a fundamental building block for developing learning abilities and behaviour self-regulation.
- Trial name
- ACT (NCT03896490)
- Testing
- Attention Control Training, Control
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Preterm Labor, Fetal Glucocorticoid Exposure
The Effect of Antenatal Corticosteroids on the Fetal Thymus - a Possible Role in Fetal Immune Programming
Administration of corticosteroids is standard practice for pregnant patients at risk of preterm labour to reduce the risk of neonatal respiratory distress syndrome, intraventricular hemorrhage, necrotizing enterocolitis and…
- Trial name
- NCT03057717
- Testing
- 2D ultrasound assessment
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Preterm Birth
Infection and Adverse Pregnancy Outcome
Miscarriage (spontaneous abortion, stillbirth, and preterm birth) is the most common adverse out-come of pregnancy and a significant proportion is caused by infection.
- Trial name
- NCT02673216
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Statens Serum Institut
Perinatal Death, Respiratory Distress Syndrome, Newborn
Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities
Hyperoxygenation for resuscitation of abnormal fetal heart rate tracings has been routine obstetric practice. However, there have not been any studies to support this practice.
- Conditions
- Perinatal Death, Respiratory Distress Syndrome, Newborn, Hypoxic-Ischemic Encephalopathy, Neonatal Seizure
- Trial name
- NCT03996317
- Testing
- Room air
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Premature Birth
Effects of Early Intervention for Preterm Children at School Age
Despite the remarkable achievements in neonatal survival of preterm infants with very low birth weight (VLBW, birth weight < 1,500 g) over the past three decades, improvements have produced little change in their prevalence of…
- Trial name
- NCT01952093
- Testing
- Home-based intervention program, Clinic-based intervention program
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Premature Birth
Prediction Tool for Premature Labour and Neonatal Outcome
A register and prediction model will be developed to predict the outcome of preterm labour and birth.
- Trial name
- PRETURN (NCT03405116)
- Where
- Belgium
- Volunteers
- 2,037 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Labor, Induction
Induction of Labor in Term Premature Rupture of Membranes: A Comparison Between Oxytocin and Dinoprostone Followed Six Hours Later by Oxytocin
Prelabor rupture of membranes (PROM) is most commonly defined as rupture of membranes before the onset of labor and occurs in 8% of term pregnancies.
- Conditions
- Labor, Induction, PROM (Pregnancy)
- Trial name
- NCT01099280
- Testing
- SYNPITAN FORT 5 IU, Propess,SYNPITAN FORT
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Premature Newborns
Dosage of Serum Tryptase Levels in a Population of Premature Newborns to Evaluate Mast Cell Activity
Compare serum tryptase levels of premature babies (<37 weeks of amenorrhea) to children born at full term. Study the evolution of serum tryptase levels in premature babies(<37 weeks of amenorrhea).
- Trial name
- NCT02787980
- Testing
- Additional taking blood
- Where
- France
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Covid19, Pregnancy Complications
Spanish Registry of Pregnant Women With COVID-19
Study title Spanish Registry of Pregnant Women with COVID-19 Protocol number and version Number 55/20. Version V8. Sponsors This registry is a project promoted by Dr.
- Conditions
- Covid19, Pregnancy Complications, Premature Rupture of Membrane, Abruptio Placentae
- Trial name
- OBS COVID (NCT04558996)
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Method of Contraception, Preterm Birth Recurrence
Optimizing Postpartum Contraception in Women With Preterm Births
The purpose of this study is to examine the effectiveness of focused family planning counseling on the uptake and continuation of highly effective contraceptive methods (defined as the intrauterine device, implant, and both male…
- Trial name
- NCT01864629
- Testing
- Focused contraception counseling
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Utah
Premature Ovarian Insufficiency
Genetic Variants in Idiopathic Premature Ovarian Insufficiency
Premature ovarian insufficiency is a condition in which ovarian function decreases or is lost before the age of 40 years. In many patients, the underlying cause remains unexplained.
- Trial name
- NCT07587853
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Abdurrahman Hamdi İnan
Infections, Rotavirus
To Assess Safety, Reactogenicity & Immunogenicity of 2 Doses of GSK's Oral Human Rotavirus Vaccine in Pre-Term Infants
This study is planned to evaluate the safety (in terms of occurrence of any serious adverse events), reactogenicity (any side effects) and immunogenicity (ability of the vaccine to develop antibodies that fight infection) of the…
- Trial name
- NCT00420745
- Testing
- Rotarix™
- Where
- 31 sites in France, Poland and 2 more
- Volunteers
- 1,009 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fetal Membranes, Premature Rupture, Preterm Premature Rupture of the Membranes
PPROM Registry (Preterm Premature Rupture of Membranes)
Preterm Premature Rupture of Membranes (PPROM) before 37 weeks of pregnancy is responsible for 40% of preterm births in the United States.
- Conditions
- Fetal Membranes, Premature Rupture, Preterm Premature Rupture of the Membranes, Oligohydramnios, Premature Birth
- Trial name
- NCT02997345
- Testing
- There is no intervention associated with this study.
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- American Alliance for pProm Support
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