Clinical trials: Premature Birth of Newborn
Premature Birth
Parental Involvement in Enteral Nutrition in Neonatal Units
Hypothesis : Bolus feeding of the newborn with a syringe under parents' visual control increases parental presence when compared to enteral feeding with a syringe pump.
- Trial name
- PREMALIM (NCT05272956)
- Testing
- enteral feeding with pushed syringe by the parents
- Where
- 2 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Limoges
Prematurity
Effectiveness Of Osteopathic Manipulative Treatment In NICU: A Multicenter Clinical Trial
The use of complementary and alternative medicine in neonatal ward has been steadily rising during the last decade. This integrated medicine approach has been shown to be helpful to improve neonatal health care.
- Trial name
- NCT01645137
- Testing
- osteopathic manipulative treatment, Usual care
- Where
- 3 sites in Italy
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Retinopathy of Prematurity (ROP)
Study on Effective Mydriasis in Premature Infants
The purpose of this study is to compare the dilating effect of 0, 1, 2 or 3 drops of mydriatic (pupil dilating) in premature infants undergoing routine retinal (eye) screening exams for Retinopathy of Prematurity (ROP).
- Trial name
- NCT01054027
- Testing
- 1% phenylephrine and 0.2% cyclopentolate
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Georgetown University
Premature Newborn
Conditions of Realization of the Echocardiography in Newborns
Experimental nociceptive stimulation of the fetus and neonate induces pulmonary artery vasoconstriction. The investigators assessed whether echocardiography for Ductus arteriosus screening may generate this hemodynamic response…
- Trial name
- NCT02893956
- Testing
- echocardiography with postural support, echocardiography with standard condition (usual)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Prematurity
Effect of Osteopathic Manipulative Treatment on Pain in Preterms
Osteopathic manipulative treatment (OMT) has been used to treat term and preterm newborns. Recent studies demonstrated the effectiveness of OMT in reducing length of stay and costs (Cerritelli, 2013) as well as the likelihood of…
- Trial name
- NCT02146677
- Testing
- Osteopathic manipulative treatment, Usual care
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Premature Birth, Bronchopulmonary Dysplasia
Assessment of Lung Structure and Function of Infants Born Prematurely
The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.
- Conditions
- Premature Birth, Bronchopulmonary Dysplasia, Asthma
- Trial name
- NCT00422305
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Indiana University
Neonatal Respiratory Distress, Preterm Birth
Study of the Feasibility of Early Lung Ultrasound in Neonatal Respiratory Distress in Premature Newborns Born Between 32 Weeks of Amenorrhea and 36 Weeks Plus 6 Days of Amenorrhea, Hospitalized in the Neonatal Pediatrics and Intensive Care Units of the Dijon University Hospital
Monocentric study carried out in the Neonatal and Intensive Care Units of the Dijon University Hospital. The objective is to evaluate the feasibility of performing a pulmonary ultrasound within 6 hours after admission in…
- Trial name
- REchoPP (NCT05737095)
- Testing
- Pulmonary ultrasound
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Feeding, Bottle, Infant, Premature, Diseases
Biobehavioral Efficacy of the Semi-Elevated Side-Lying Position
The objective of the proposed research is to conduct a within-subject cross-over trial that will compare the efficacy of the two bottle-feeding positions on physiologic and behavioral responses of preterm infants prior to…
- Conditions
- Feeding, Bottle, Infant, Premature, Diseases, Behavior, Infant
- Trial name
- NCT04942106
- Testing
- Arm 1 - Side-lying position followed by Supine position, Arm 2 - Supine position followed by Side-lying position
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston College
Bronchopulmonary Dysplasia
Effect of Synchronized vs. Continuous HFNC Using NAVA on WOB in Infants With BPD
Patients will be randomized to begin the study with either NAVA-synchronized or continuous HFNC. Each patient will receive two 15-minute trials at different levels of continuous HFNC and two 15-minute trials at corresponding…
- Trial name
- NCT04274192
- Testing
- Synchronized HFNC at 6 liters per minute (LPM), Continuous HFNC at 6 liters per minute (LPM), Synchronized HFNC at 8 liters per minute (LPM)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Arkansas
Prematurity, Mechanical Ventilation
The Effect of Breast Milk Odor and Swaddling on Physiological Parameters and Stress Levels in Premature Infants Receiving Ventilator Support
It will be done to shorten the hospital stay of the newborn and increase the quality of care by proving the positive effect of the safe wrapping method and the smell of breast milk on the physiological parameters and stress level…
- Trial name
- NCT07681934
- Testing
- Breast Milk Smell, Arson, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- KTO Karatay University
Bronchopulmonary Dysplasia, Respiratory Distress Syndrome in Premature Infant
Budesonide With Intratracheal Surfactants in Extremely Preterm Infants
This is a phase I/II trial in preterm infants aimed at identifying the optimal dose of budesonide with bovine lipid extract surfactant as vehicle for intratracheal administration.
- Trial name
- BITS (NCT04019106)
- Testing
- Budesonide in bovine lipid extract surfactant (BLES)
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Neonatal Disease
Analysis of Differential Proteins and Maternal Influencing Factors of Septic Shock in Neonates
1. Explore 32 weeks of premature infants or maternal pregnancy infection of newborn septic shock maternal influence factors. 2. Through maternal blood samples before delivery and labor cord blood sample screening and septic shock…
- Trial name
- NCT06206590
- Testing
- Whole-proteomic assay
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Guangdong Women and Children Hospital
Intensive Care Units, Neonatal, Infant, Newborn
Heterogeneity Index in Neonatologist-performed Lung Ultrasound in Neonates Receiving Respiratory Support - a Pilot Study
Lung ultrasound is an increasingly valuable diagnostic tool in neonatal intensive care due to its safety and accessability. This pilot study investigates whether a quantitative approach - the heterogeneity index, previously only…
- Conditions
- Intensive Care Units, Neonatal, Infant, Newborn, Infant, Premature, Point-of-Care Systems
- Trial name
- NPLUS HI (NCT07117513)
- Where
- 2 sites in Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Graz
Retinopathy of Prematurity
Vascular Endothelial Growth Factor in Stage V ROP
Vascular Endothelial Growth Factor (VEGF) is a dimeric glycoprotein, naturally expressed in epithelial and tumor cells (1). Normal Retinal vascularization has two phases: In the first fase, cells of mesenquimatous origin form the…
- Trial name
- NCT00500396
- Testing
- Open-Sky Vitrectomy
- Where
- Mexico
- Volunteers
- 15 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Retinopathy of Prematurity
Incidence of Hypoxia During Intravitreal Anti-VEGF (Vascular Endothelial Growth Factor) Injections for Retinopathy of Prematurity (ROP) Under Topical Anesthesia
Purpose: To evaluate the incidence and severity of hypoxia and address a genuine evidence gap focusing on intraprocedural hypoxia during bedside intravitreal ranibizumab injection for retinopathy of prematurity (ROP), an area…
- Trial name
- NCT07701759
- Testing
- ranibizumab
- Where
- Saudi Arabia
- Volunteers
- 74 people
- Sponsor
- Minia University
Bronchopulmonary Dysplasia
Clarithromycin Prophylaxis in Preterm Infants Colonisation With Ureaplasma Urealyticum and Mycoplasma Hominis
The purpose of this study is to determine of clarithromycin effect on developing of bronchopulmonary dysplasia in preterm babies.
- Trial name
- Claprum (NCT01652118)
- Testing
- clarithromycin treatment for prophylaxis of bronchopulmonary dysplasia, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Fullterm Birth, Neonate
Assessment of Autonomic Maturation in Neonatal Period and Early Neural Development From a Longitudinal Prospective Cohort
The heart rate variability assessment of the sympathetic-parasympathetic balance is a strong analytical tool in the autonomic nervous system (ANS) physiology, at each end of life.
- Conditions
- Fullterm Birth, Neonate, Prematurity
- Trial name
- AUBE (NCT00951860)
- Testing
- Autonomic Nervous System activity
- Where
- France
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Retinopathy of Prematurity
UK Surveillance of Treated Retinopathy of Prematurity
Currently, there is little recent data on regional variations in treatment methods, neonatal units that provide retinopathy (ROP) treatment, facilities for treatment available at each unit including anaesthetic support for such…
- Trial name
- NCT02484989
- Testing
- Surviellance card
- Where
- United Kingdom
- Volunteers
- 270 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Extremely Low Birth Weight
The Effect of Schumann Resonance on Preterm Newborns
Body weight gain is crucial for preterm newborns, especially those with a low birth weight. Owing to their noninvasive, noncontact, and non-pharmaceutical properties, extremely low frequency electromagnetic fields (ELF-EMFs) are…
- Trial name
- NCT05146752
- Testing
- extremely low frequency electromagnetic fields, routine care
- Where
- Taiwan
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Neonatal Hypotension
Early Use of Hydrocortisone in Hypotensive Very Low Birth Weight Infants
The purpose of this study is to investigate the early use of hydrocortisone in hypotensive very low birth weight infants. Based on the observations that: hypotension is a common problem in very low birthweight infants and is…
- Trial name
- NCT00358748
- Testing
- Hydrocortisone
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
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