Clinical trials: Premedication
Postoperative Nausea and Vomiting
Gabapentin to Reduce Postoperative Nausea and Vomiting
The intrathecal administration of morphine is gaining popularity. It is easy to do and can reduce the pain after surgery up to 24 hours.
- Trial name
- NCT02944981
- Testing
- Gabapentin
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Hemodynamic Response to Laryngoscopy and Orotracheal Intubation
Effect of Nalbuphine on Hemodynamic Response During Laryngoscopy and Intubation
Laryngoscopy and placement of a breathing tube during general anesthesia can cause temporary increases in blood pressure and heart rate. These changes may be harmful in some patients.
- Trial name
- NAL-HRI (NCT07348159)
- Testing
- Normal saline IV, Nalbuphine 0.2 mg/kg
- Where
- Pakistan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Dr. Waseem Ullah
Preoperative Sedation
Nebulized vs. Oral Midazolam Sedation in Pediatric Anesthesia: A Randomized Comparative Study
This study is to be carried out to compare nebulized and oral midazolam in achievement of a satisfactory level of sedation, Ramsey Sedation Score (RSS) of 4, within 30 mins of midazolam administration in pediatrics.
- Trial name
- NCT04760041
- Testing
- Midazolam nebulized, Midazolam oral solution
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endoscopy, Digestive System
Impact of Timing of Premedication on Mucosal Visibility During Endoscopy-A Randomized Controlled Trial
UGI endoscopy(esophagogastroduodenoscopy) is the main diagnostic modality for direct visualization ,real time assessment and interpretation of findings encountered.
- Trial name
- ENDO (NCT06581783)
- Testing
- Simethicone plus NAC
- Where
- India
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Pediatric, Anesthesia
Comparison of Oral Dexmedetomidine, Ketamine Versus Midazolam for Premedication in Children Undergoing Injuinal Surgeries
The aim of this study is to compare between oral dexmedetomidine, Ketamine or midazolam for premedication in children undergoing inguinal hernia surgeries.
- Trial name
- CODKMPCIS (NCT06879496)
- Testing
- Oral ketamin, Oral Midazolam, Oral dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cardiovascular Diseases
Predictive Medicine Research. (PRE MED)
Principal Investigator: Arshed A. Quyyumi, MD To establish normal values by age, race, and gender of novel markers of risk in healthy subjects necessary to predict precise risk of cardiovascular disease in an individual.
- Trial name
- NCT00336570
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Emory University
Anxiety Reduction, Elective Cesarean Section
Preoperative Auricular Acupuncture in Elective Cesarean Section.
Preoperative anxiety before cesarean section is common and may be severe. Stress consequences are often deleterious for the mother and for the upcoming newborn. Means to reduce anxiety before cesarean section are limited.
- Trial name
- CESAUR (NCT02707705)
- Testing
- Apply an auricular acupuncture protocol by stimulating specific points of the ear with needles inserted on adhesive tape (Pyonex®)., Apply a device having no real effect, Disinfection
- Where
- France
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Anxiety
Is Virtual Reality a Non-pharmacological Premedication?
Preoperative anxiety of patients who will undergo septorhinoplasty surgery will be measured and their hemodynamic parameters will be recorded afterwards.
- Trial name
- NCT04598217
- Testing
- anesthesiologist
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Irreversible Pulpitis
Effect of Premedication on Success of Inferior Alveolar Nerve Block Injection
The aim of this study is effect of premedication on success of inferior alveolar nerve block injection. Sixty healthy adult volunteers including criteria, are participating.
- Trial name
- NCT02601911
- Testing
- Ketorolac Tromethamine, Acetaminophen
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Irreversible Pulpitis
Premedication Efficacy of Ketorolac Infiltration on Post Endodontic Pain
Objective: The aim of this study is to evaluate premedication with ketorolac infiltration on post endodontic pain in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT02923687
- Testing
- Ketorolac Tromethamine
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Postoperative Sleep Disturbance
Dexmedetomidine Premedication for Post-anaesthesia Sleep Disturbance
The goal of this clinical trial is to learn about the effect of preoperative nasal spry with dexmedetomidine on postoperative sleep disturbance in young to middle-aged women undergoing hysteroscopy.
- Trial name
- NCT06281561
- Testing
- Normal Saline, Dexmedetomidine
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xiamen University
Premedication
Dexmedetomidine Premedication in Children
The aim of this retrospective study was to detect the effectiveness of 1µg/kg oral dexmedetomidine premedication on preoperative cooperation and emergence delirium of the the young children underwent complete dental treatment.
- Trial name
- NCT03174678
- Testing
- Dexmedetomidine, apple juice
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Blood Loss
Clonidine Versus Tranexamic Acid in Reduction of Blood Loss
Tranexamic acid is an antifibrinolytics agent that has been widely used in the reduction of blood loss at surgeries. Oral clonidine is an alpha-2 adrenergic agonist that has been used in various surgeries including Caesarean…
- Trial name
- NCT05371574
- Testing
- clonidine group
- Where
- Nigeria
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Uwakwe Emmanuel Chijioke
Anxiety, Postoperative Pain
Sublingual Melatonin for Anxiety and Pain in Elective Gynecologic Surgery
This prospective randomized controlled study aims to evaluate the anxiolytic effect of preoperative sublingual melatonin and its impact on postoperative pain scores when administered in two different doses to female patients…
- Conditions
- Anxiety, Postoperative Pain, Anesthesia
- Trial name
- NCT06997263
- Testing
- Melatonin 3 mg Sublingual, Melatonin 6 mg Sublingual
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Benha University
Dental Surgeries
Comparison of Nebulized Fentanyl, Midazolam and Dexmedetomidine as a Premedication in Pediatric Dental Surgeries
The preoperative time can be traumatic for young children undergoing surgery. Pediatric anesthesiologists act strongly to decrease distress for children in the operating room (OR) and to provide a smooth induction of anesthesia.
- Trial name
- NCT04226885
- Testing
- fentanyl, midazolam, dexmedetomidine
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Monitored Anaesthesia Care, Loco-regional Chronic Subdural Hematoma Evacuation
Oral Melatonin as Premedication During MAC for Patients Undergoing Loco-regional Chronic Subdural Hematoma Evacuation
investigators assume that administration of preoperative melatonin will reduce the required dose of propofol in participants undergoing loco-regional chronic subdural hematoma evacuation, it may as well provide better…
- Trial name
- NCT03732963
- Testing
- Melatonin (Group M)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain
Pain is a very important factor in Endodontic treatment, Both intra- and Post-operatively. In case of symptomatic Irreversible pulpitis, a build up of inflammatory mediators makes it very difficult for the operator to reach the…
- Trial name
- NCT06298383
- Testing
- Trypsin, Bromelain and Rutoside, Diclofenac Potassium 50mg Tab, Prednisolone Oral Tablet
- Where
- 2 sites in Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ketamine Induced Agitation
Reducing Ketamine-Induced Agitation, by Midazolam or Haloperidol Premedication After Adult Procedural Sedation
Ketamine is the cornerstone of procedural sedation in emergency department but ketamine induced agitation has limited its usage by many physicians.
- Trial name
- NCT02909465
- Testing
- Midazolam, Haloperidol, Ketamine
- Where
- Iran
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Colonoscopy
Usefulness Of Flospan As A Premedication For Colonoscopy
Usefulness of Flospan as a premedication for colonoscopy: A randomized double-blind controlled trial
- Trial name
- NCT01842932
- Testing
- Phloroglucin, Cimetropium bromide, Colonoscopy
- Where
- South Korea
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Symptomatic Irreversible Pulpitis
Effectiveness of Premedication on the Success Rate of Inferior Alveolar Nerve Block
Purpose: The aim of this prospective, double-blind, randomized controlled trial is to compare the effect of oral premedication of dexamethasone, ketorolac, meloxicam, ibuprofen or placebo on the success of inferior alveolar nerve…
- Trial name
- NCT05097768
- Testing
- Dexamethasone 0.5mg, Ketorolac 10 Mg Oral Tablet, Meloxicam 7.5 mg
- Where
- Saudi Arabia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Alfarabi Colleges