Clinical trials: Premenopausal
Pharmacokinetics
Pharmacokinetic Study of Raltegravir in Healthy Premenopausal Women.
Healthy subjects will take study drug by mouth twice a day for 7 consecutive days, blood and cervicovaginal samples will be taken most mornings around the AM dose. Two visits, ~14 hrs in length will be required on Day 1 and 7.
- Trial name
- NCT00746499
- Testing
- Raltegravir
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Fertility
An Ethno-bridging Study of Pergoveris in Healthy Premenopausal Participants of Japanese or Caucasian Origin
The purpose of this study is to assess the Pharmacokinetic (PK) of Recombinant human follicle-stimulating hormone (follitropin alfa) (r-hFSH) and Recombinant human luteinizing hormone (lutropin alfa) (r-hLH) following a single…
- Trial name
- NCT07269327
- Testing
- Desogestrel and ethinylestradiol fixed dose combination, Follitropin alfa/lutropin alfa
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Pelvic Floor
A Cross-sectional Study of Female Pelvic Floor Muscle Function in Chinese Healthy Female
This study aims to investigate the status of pelvic floor function of healthy female in China, including premenopausal nullipara, premenopausal women with childbirth and postmenopausal women.
- Trial name
- NCT03516266
- Where
- China
- Volunteers
- 7,920 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Preeclampsia
Safety, Tolerability, and PK/PD of Telpegfilgrastim in Premenopausal Non-pregnant Females
This is an open-label, Phase Ia clinical study to evaluate the safety, tolerability, and pharmacokinetic/pharmacodynamic (PK/PD) characteristics of single dose of telpegfilgrastim injection in healthy premenopausal non-pregnant…
- Trial name
- NCT06893796
- Testing
- Telpegfilgrastim Injection
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Xiamen Amoytop Biotech Co., Ltd.
Endometriosis
A Study of HS-10518 in Healthy Female Participants
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HS-10518 in healthy adult premenopausal females in China.
- Trial name
- NCT06118827
- Testing
- HS-10518
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Osteoporosis Risk
Evaluation of the Effects of Bicarbonate-calcium Water in Premenopausal and Postmenopausal Women as a Prevention of Osteoporosis
The goal of this clinical trial is to evaluate the effect of bicarbonate-calcium water for the prevention of osteoporosis. Participants are women in pre- or post- menopausal state.
- Trial name
- NCT05854342
- Testing
- bicarbonate-calcium water
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Salerno
Fertility
Fertility in Healthy Premenopausal Women
The study objectives are described below: 1. Obtain serum specimens collected for one ovulatory cycle or a maximum of 33 days, but not to exceed a total of 550 ml of whole blood per subject from a minimum of 60 healthy…
- Trial name
- NCT02772848
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujirebio Diagnostics, Inc.
Folliculogenesis
An Open-label Study of the Effects of Elagolix in Adult Premenopausal Females
This is an open-label Phase 1 study in healthy premenopausal females evaluating the effects of different dosing regimens of elagolix on ovarian activity, ovulation, and ovarian reserve and to assess the effect of elagolix on…
- Trial name
- NCT01403038
- Testing
- Elagolix
- Where
- 22 sites in United States, Puerto Rico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- AbbVie (prior sponsor, Abbott)
Japanese Premenopausal Healthy Adult Women
A Food Effect Study of TAK-385 Final Formulation
The purpose of this study is to evaluate food effects on the pharmacokinetics of a single oral dose of TAK-385 in Japanese premenopausal healthy adult women.
- Trial name
- NCT02792062
- Testing
- TAK-385 40 mg
- Where
- Japan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Takeda
Dietary Modification
Green Vegetables and Women's Health
The 2010 Dietary Guidelines for Americans recommend that individuals consume 4.5 to 5 cups fruits and vegetables daily. However, at current intake levels, fruit consumption will have to improve by more than 100% and vegetable…
- Trial name
- NCT01726127
- Testing
- Broccoli and Brussels Sprouts, Cruciferous Complete
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Iron Deficiency (Without Anemia)
Efficacy of a Low Dose, Oral, Liquid Iron Supplement on Restoring Inadequate Blood Iron to Normal Levels
This is a randomized, double-blind, placebo-controlled, 8-week intervention clinical study assessing the safety and efficacy of a new low-dose liquid iron supplement in restoring iron levels to normal ranges without promoting…
- Trial name
- NCT05257343
- Testing
- Liquid Iron Supplement (Blood Builder ®)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Menstruation Disturbances, Luteal Phase Defect
Energy Restriction and Hormones in Premenopausal Women
A growing body of epidemiological and biological evidence strongly suggests that physical activity may reduce the risk of breast cancer.
- Trial name
- NCT05107804
- Testing
- Exercise+CR, Light Conditioning
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cancer Free Women
MRI Parenchymal Enhancement: A New Marker of Breast Cancer Risk
The purpose of this study is to learn about how a woman's health history influences what a normal breast looks like on an MRI. The investigators also want to learn about how the amount of different natural hormones a woman has…
- Trial name
- NCT01649661
- Testing
- questionnaire
- Where
- United States
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Menstrual Wellness
Radicle Menstrual Wellness™ CSP: A Trial Evaluating Plant-Based Health and Wellness Products on Menstrual Wellness in Premenopausal Women
A randomized, double-blind, placebo-controlled, trial evaluating plant-based health and wellness products on menstrual wellness in premenopausal women
- Trial name
- NCT07138339
- Testing
- Menstrual Wellness Product 1
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Uterine Fibroids
Endometrial Preparation Before Operative Hysteroscopy in Premenopausal Women
The presence of a thin endometrium has an important role in allowing the best conditions for hysteroscopic surgery. The aim of this study is to evaluate the efficacy of a 21 day administration of 2 mg of dienogest versus…
- Trial name
- NCT02440750
- Testing
- operative hysteroscopy, Dienogest, Ulipristal acetate
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Pharmacokinetics
Clinical Study Investigating the Conversion of the Contraceptive Compound Norethisterone Within the Body Towards the Contraceptive Compound Ethinylestradiol
The clinical phase I study aims at investigating the conversion of the contraceptive compound norethisterone within the body towards the contraceptive compound ethinylestradiol.
- Trial name
- NCT02170038
- Testing
- Microgynon, Noristerat(BAY86-6308)
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bayer
Menopause, Cardiovascular
Comparing the Effects of Multicomponent Exercise on Cardiovascular Health and Lipid Profiles in Premenopausal and Postmenopausal Women
Background: The present study aimed to examine the effects of a 26-week multicomponent exercise program on lipid and lipoprotein profiles, blood pressure, and anthropometric parameters in healthy but sedentary premenopausal and…
- Trial name
- NCT06802484
- Testing
- Experimental: Pre-Menopausic, Experimental: Post- Menopausic
- Where
- Portugal
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Évora
Contraception, Bone Metabolism
Bone Metabolism in Premenopausal Exercising Women
The main goal of this study is to examine how sex hormones and low energy availability affect the concentrations of bone remodelling markers at rest and after a running protocol.
- Conditions
- Contraception, Bone Metabolism, Low Energy Availability, Eumenorrhea
- Trial name
- BeWOMEN (NCT06961773)
- Testing
- Low energy availability, High energy availability
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Hepatitis C, Chronic
Drug-drug Interaction of BI 201335 and Microgynon
This study will investigate possible effect of multiple oral doses of BI 201335 on the steady state pharmacokinetics of ethinylestradiol and levonogestrel
- Trial name
- NCT01570244
- Testing
- levonorgestrel, Ethinylestradiol, BI 201335
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Menstruation Disorders
Partial Double-Blind, Placebo-Controlled Study to Assess the Effect of Anastrozole on the Endometrium in Healthy Volunteers
Aromatase inhibitors have been approved for use in postmenopausal women to treat and prevent breast cancer. They act by blocking the action of the enzyme, aromatase, that is necessary for the production of estradiol.
- Trial name
- NCT00467493
- Testing
- Anastrozole
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Meditrina Pharmaceuticals