Clinical trials: Premenopausal Women
Polycystic Ovary Syndrome
Prevalence of Polycystic Ovary Syndrome (PCOS) in Obese Premenopausal Women
Between 40% and 85% of women with Polycystic Ovary Syndrome (PCOS) are overweight or obese and obesity is closely linked to the development of PCOS.
- Trial name
- NCT01319162
- Testing
- Weight reduction regimen
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Dysfunction; Endocrine, Effects of Chemotherapy
Blood Spot Self-administered Test and Assay
The current study will compare hormone levels of AMH, FSH and inhibin B in blood specimens collected by venipuncture and fingerstick in a sample of pre-menopausal women ages 18-45 years with normal menstrual cycles.
- Conditions
- Dysfunction; Endocrine, Effects of Chemotherapy, Premature Ovarian Failure
- Trial name
- NCT03840824
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Infertility, Female
A Study of HS-10518 in Healthy Adult Premenopausal Females in China
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HS-10518 in healthy adult premenopausal females in China
- Trial name
- NCT07264192
- Testing
- HS-10518
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
Obese, Elevated Blood Pressure
Mat Pilates and Vascular Function in Obese Females
Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as…
- Trial name
- NCT03907384
- Testing
- Mat Pilates training
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marymount University
Mammographic Density
A Single Dose Trial to Evaluate the Pharmacokinetics of Testosterone and Anastrozole
A single dose trial to evaluate the pharmacokinetics of testosterone and anastrozole from subcutaneous testosterone and anastrozole (T+Ai) in premenopausal women
- Trial name
- NCT03314298
- Testing
- testosterone anastrozole
- Where
- Australia
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Havah Therapeutics Pty Ltd
Menopause, Visceral Adipose Tissue Accumulation
Developing an Intervention to Prevent Visceral Adipose Tissue Accumulation
The aim of this study is to develop an intervention that will produce a sustained improvement in physical activity and chronic stress as a means to slow the menopause-related accumulation of visceral adipose tissue in mid-life…
- Conditions
- Menopause, Visceral Adipose Tissue Accumulation, Abdominal Obesity, Obesity
- Trial name
- NCT01778712
- Testing
- Multi-level intervention
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Breast Cancer
Acolbifene in Preventing Cancer in Premenopausal Women at High Risk of Breast Cancer
This phase II trial is studying how well acolbifene works in preventing cancer in premenopausal women at high risk of breast cancer. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Trial name
- NCT00853996
- Testing
- acolbifene hydrochloride
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Breast Cancer
Study of Vitamin D for Premenopausal Women at High Risk for Breast Cancer
This proposal is for a pilot study of 20 premenopausal women at high risk for breast cancer development who will receive high dose vitamin D3, cholecalciferol 20,000 IU (2 capsules) weekly, or 30,000 IU (3 capsules) weekly, for 1…
- Trial name
- NCT00976339
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Katherine D. Crew
Healthy
Pergoveris FD and Liquid China BE Study
The main purpose of this study is to assess the bioequivalence (BE) of the fixed combination of follitropin alfa and lutropin alfa in Pergoveris freeze-dried (FD) (Test 1) or in Pergoveris Liquid (Test 2) versus the…
- Trial name
- NCT04899193
- Testing
- Pergoveris FD, Pergoveris Liquid, Gonal-f
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Breast Cancer
Effect of 4-Hydroxytamoxifen Gel on Breast Density, Salivary Sex Steroids, and Quality of Life in Premenopausal Women
RATIONALE: High estrogen levels may be associated with dense breast tissue and an increased risk of developing breast cancer. 4-hydroxytamoxifen gel (a substance made when tamoxifen breaks down in the body) may be effective in…
- Trial name
- NCT00084344
- Testing
- 4-hydroxytamoxifen, breast imaging study, radiomammography
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Female Sexual Dysfunction
PK Study of Testosterone Nasal Gel (TBS-2) in Healthy Premenopausal Women
The purpose of this study was to assess the bioavailability of total testosterone through pharmacokinetic profiles obtained following (a) single administration of three doses of TBS-2 b) multiple administration TBS-2.
- Trial name
- NCT01364623
- Testing
- Low dose testosterone nasal gel, single dose, Medium dose testosterone nasal gel, single dose, High dose testosterone nasal gel, single dose
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Acerus Pharmaceuticals Corporation
Healthy Volunteers, Female
Progesterone and Muscle Protein Synthesis in Premenopausal Women (MP4-MPS)
The goal of this clinical trial is to learn if micronized progesterone (PROMETRIUM®) influences the muscle-building response to resistance exercise in healthy premenopausal women aged 18-30 years.
- Conditions
- Healthy Volunteers, Female, Progesterone, Premenopausal
- Trial name
- MP4 MPS (NCT07173361)
- Testing
- Micronized progesterone (oral capsules)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Sedentary
Comparison of Gut Microbiota in Sedentary and Active Women
Gut microbiota comparison of active and sedentary women
- Trial name
- NCT02901912
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Healthy, Premenopausal Period
Effects of Omega-3 Fatty Acids on Risk Factors for Breast Cancer in Pre-menopausal Women
Healthy premenopausal women were enrolled in a diet intervention study that examined the effect of a combination EPA/DHA supplement on risk factors associated with breast cancer.
- Trial name
- NCT02816125
- Testing
- omega-3 fatty acid
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Healthy Adult Premenopausal Female Volunteers
Study of the Effect of ITCA 650 on the PK/PD of Oral Contraceptive in Healthy Female Subjects
A Phase 1, randomized, double-blind, placebo-controlled, crossover study to assess the effect of ITCA 650 on the pharmacokinetics (PK) of once daily administration of Levora® (ethinyl estradiol 0.3 mg (EE) and levonorgestrel 0.15…
- Trial name
- NCT02641990
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Intarcia Therapeutics
Premenopausal Women
Effect of Plyometric Exercises in Premenopausal Women
It was aimed to examine the effects of plyometric exercises on muscle strength in this study. 26 premenopausal women assigned to one of the three groups: Control Group (n=8), Plyometric Exercise Group (n=10) and Isokinetic…
- Trial name
- NCT04809857
- Testing
- Exercise
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Healthy
Drug-drug Interaction of Empagliflozin (BI 10773) and Microgynon
The objective of this study is to investigate the possible effect of multiple oral doses of 25 mg BI 10773 on the steady state pharmacokinetics of ethinylestradiol (EE) and levonogestrel (LNG) (Microgynon®).
- Trial name
- NCT01328184
- Testing
- levonorgestrel, Ethinylestradiol, Microgynon + BI 10773
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Menopause
Menopause and Oral Microbiome
The study examines the saliva and dental plaque microbiome of women aged 35-65 in two groups: postmenopausal (case) and premenopausal (control). For this purpose, Illumina Platform to sequence 16S rRNA gene regions will be used.
- Trial name
- NCT05335733
- Testing
- Intraoral examination, saliva, dental plaque and serum collection.
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Ege University
Non-anemic Iron Deficiency
Low-dose Iron Supplementation and Markers of Iron Status Among Non-anemic, Iron-deficient Women
Healthy premenopausal women that are iron-deficient without anemia will receive a low-dose iron dietary supplement. The investigators seek to determine if the low-dose iron dietary supplement will restore iron levels to normal…
- Trial name
- NCT02683369
- Testing
- Blood Builder®/Iron Response®
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Overweight
Orlistat Induced Modulation on the Fatty Acid Composition in Obese Females
Orlistat is a popular drug approved for long-term use which produces weight loss by inhibiting triglycerides, main components of fats in the diet and reducing dietary fat absorption by up to 30%.
- Trial name
- NCT01414465
- Testing
- Orlistat
- Where
- Brazil
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil