Clinical trials: Prenatal Care
Pregnant Women, Prenatal Care
MatErnal BLood IS Source to Accurately Diagnose Fetal Aneuploidy
The primary objective of this study is to determine the performance characteristics (sensitivity and specificity) of the Verinata Health Test to detect fetal Trisomy 21 (T21) compared to karyotype results obtained by…
- Trial name
- MELISSA (NCT01122524)
- Where
- 11 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- Verinata Health, Inc.
Crohn's Disease, Prenatal Exposure
Pregnancy Exposure Registry for Tysabri®
The primary objective of the Registry was to evaluate the outcomes of pregnancy in women with Multiple Sclerosis (MS) or Crohn's Disease (CD) who were exposed to TYSABRI® at any time within 90 days prior to first day of Last…
- Conditions
- Crohn's Disease, Prenatal Exposure, Multiple Sclerosis, Pregnancy
- Trial name
- NCT00472992
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- Biogen
Pregnancy
Development of a Non-invasive Prenatal Test
This is an observational study to aid in the development of a non-invasive prenatal test that may be used to aid in detection of fetal aneuploidy.
- Trial name
- NCT01451684
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- Cindy Cisneros
Fetal Complications
Development of a Prenatal Test for Fetal Aneuploidy Detection
This is an observational study to develop and evaluate a blood based prenatal blood test. Pregnant women confirmed to be carrying a fetus with a chromosomal abnormality will be eligible.
- Trial name
- NCT01451671
- Where
- 3 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Cindy Cisneros
Pregnancy, Prenatal Care
Comparing AI and Standard Pregnancy Chatbots
Many pregnant women in India use mobile phones to get health information. Nivi runs a free WhatsApp service called askNivi that answers questions about pregnancy and sends reminders about prenatal care visits.
- Conditions
- Pregnancy, Prenatal Care, Maternal Health
- Trial name
- NCT07883993
- Testing
- Scripted maternal health chatbot, MATRI retrieval-augmented maternal health chatbot
- Where
- India
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Nivi, Inc.
Fetal Monitoring
A Clinical Study for Validating the Equivalence of Bloomlife MFM-Pro to Clinical Standard-of-care for Antepartum Fetal Monitoring
Bloomlife has developed a wearable system (Bloomlife MFM-Pro) that can allow fetal monitoring to be conveniently performed in healthcare settings under supervision of a healthcare professional.
- Trial name
- NST (NCT05060172)
- Testing
- Bloomlife MFM-Pro
- Where
- Belgium
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Bloom Technologies
Prenatal Screening, Pregnancy Related
Fetal Cell Analysis From Maternal Blood
The aim of this clinical study is the evaluation of clinical performance of a cell-based non-invasive test technology for fetal aneuploidies and segmental imbalances detection in a high-risk pregnancies population.
- Conditions
- Prenatal Screening, Pregnancy Related, Genetic Disease
- Trial name
- NCT05671744
- Testing
- Cell-based non-invasive prenatal testing
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Menarini Biomarkers Singapore
Ultrasonography, Prenatal
Instinct™ Ultrasound Device Safety, Efficacy and Usability
Mobile medical devices for self-patient-use, are a rapidly evolving component of telehealth. Study examines the feasibility of using the INSTINCT® device, a portable self-use ultrasound system attached to a commercial smartphone…
- Trial name
- NCT04399408
- Testing
- Obstetrics Ultrasound (non invasive)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- PulseNmore
Trisomy 13, Trisomy 18
Multiple Gestation Study
The objectives of the clinical study are to demonstrate the accuracy of our new NATUS diagnostic method to determine the genetic health of the developing fetuses in a multiple gestation pregnancy from a maternal blood sample.
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
- Trial name
- NCT02278536
- Where
- 8 sites in United States, India and 1 more
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Pregnancy Related
Rewarding Healthy Behaviors in Pregnancy and Postpartum
This is a single-arm pilot clinical trial with two primary research goals: 1. To test the efficacy of a software's ability to profile eligible individuals who decline participation in a clinical trial ("non-consenters") so that…
- Trial name
- NCT05328622
- Testing
- Aqueduct Contingency Management Platform
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Transcendent International, LLC
Pregnancy, Fetal Monitoring
Use of In-Home Non-Stress Monitoring Device for Fetal Monitoring: A Nonsignificant Risk (NSR) Device Study
This study evaluates the safety and performance of the PregnaOne System, a non-significant risk (NSR) investigational medical device for in-home fetal monitoring in pregnant women during the third trimester.
- Trial name
- NCT07223996
- Testing
- PregnaOne System
- Where
- 3 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Nestmedic Spolka Akcyjna
Antenatal Care, Maternal Health
AI Blind-Sweep Ultrasound for Antenatal Screening by Non-Specialist Health Workers in Rural DR Congo
FS2 evaluates the diagnostic accuracy and implementation feasibility of an AI-assisted blind-sweep obstetric ultrasound (SPAQ E-con AI), operated by trained non-specialist health workers, for antenatal screening in rural…
- Conditions
- Antenatal Care, Maternal Health, Gestational Age, Placenta Praevia
- Trial name
- FS2 (NCT07677670)
- Testing
- SPAQ E-con AI blind-sweep ultrasound
- Where
- Democratic Republic of the Congo
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- SOIK Corporation Sarl
Pregnancy Related, Nutrient Deficiency
Prenatal Nutrient Status Study
The purpose of this research is to gather data on nutritional status from approximately 250 pregnant women who are currently taking a prenatal vitamin in order to better understand if the prenatal vitamins that most people use…
- Trial name
- NCT06156826
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- Needed PBC
High Risk Pregnancy
Investigation of the Impact of Noninvasive Prenatal Testing for Fetal Aneuploidy on Utilization of Prenatal Diagnostic Procedures and Pregnant Women's Views
This is a prospective, single-institution observational study to be conducted at 4 clinics within the Southern California Permanente Medical Group.
- Trial name
- NCT01708746
- Where
- 4 sites in United States
- Volunteers
- 205 people
- Sponsor
- Verinata Health, Inc.
Infant Development, Gut Microbiome
Characterisation of the Gut Microbiota in Term Infants After Maternal Supplementation of Probiotics
A monocenter, open label pilot study in pregnant women and their offspring with at least four weeks prenatal and four weeks postnatal maternal intervention with a study product consisting of four different food constituents.
- Trial name
- NCT04987593
- Testing
- Probiotics
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Pregnancy
Evaluating the Safety of PregSense™ and Compare Its Performance to CTG in Prenatal Monitoring of Pregnant Subjects
This clinical study will evaluate the safety of PregSense™ and Comparative Performance of PregSense™ versus CTG in Prenatal Monitoring of Pregnant subjects.
- Trial name
- NCT03504189
- Testing
- PregSense™, Cardiotocopraphy (CTG)
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 151 people
- Sponsor
- Nuvo-Group, Ltd.
Pregnancy Related
Human Anti-D (rh) Immunoglobulin (Rhesoglobin) Efficacy, Safety and Some Pharmacokinetics Parameters in Pregnant Women
Rhesus conflict between mother and fetus is due to the different antigenic composition of erythrocytes. During the first pregnancy, sensitization of the mother to fetal erythrocytes rhesus D (RhD) antigens is formed.
- Trial name
- NCT05245734
- Testing
- Human Anti-D (rh) immunoglobulin
- Where
- 16 sites in Ukraine
- Volunteers
- 281 people
- Sponsor
- Biopharma Plasma LLC
Gestational Diabetes
Protocol to Validate the Performance of the Mellitus Glycated CD59 ELISA for Gestational Diabetes Screening
Demonstrate effective performance of the Mellitus GCD59 Test (an ELISA) in screening for gestational diabetes mellitus (GDM)
- Trial name
- NCT03865901
- Testing
- Mellitus GCD59 Test
- Where
- 19 sites in United States
- Sponsor
- Mellitus, LLC
Pregnancy Related
Cell-Based Noninvasive Prenatal Testing
The purpose of the overall study is to develop improved methods for recovery and analysis of fetal cells from the mother's blood in order to develop clinically useful forms of cell-based, diagnostic, noninvasive prenatal testing…
- Trial name
- NIPT (NCT05245266)
- Testing
- Redraw for analysis of blood samples from healthy pregnant women
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Luna Genetics
Pregnancy Following IVF With PGS/PGD
Collection of Maternal Blood Samples for Development of Non-invasive Prenatal Diagnostic Testing
The purpose of this study is to collect blood samples from pregnant women who achieved pregnancy following in-vitro fertilization (IVF) with Natera's preimplantation aneuploidy screening (with or without single gene gene…
- Trial name
- NCT01546324
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Natera, Inc.