Clinical trials: Prenatal Care
Pregnancy
Safety and Performance of a Fetal Monitoring System
The objective of this study is to demonstrate the safety and performance of the M•care™ System for use in antenatal monitoring of pregnant women ≥ 32 weeks' gestation.
- Trial name
- M•CARE SE (NCT05294211)
- Testing
- M•care™ System, Cardiotocography (CTG)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Marani Health
Maternal Psychological Distress, Prenatal Stress
Roo Study on Mom and Baby Well-Being
This study employs a randomized controlled trial of an established intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, to examine effects on various aspects of maternal psychological stress during…
- Conditions
- Maternal Psychological Distress, Prenatal Stress, Infant Development, Functional Neuroimaging
- Trial name
- NCT03809598
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pregnancy
Delivery Vehicles for Prenatal Calcium Supplementation
The SickKids-led research team is currently developing a prenatal micronutrient powder that will contain calcium, iron, and folic acid with different absorption characteristics.
- Trial name
- NCT01676636
- Testing
- Traditional Tablet, Chewable tablets, Unflavoured Powder
- Where
- 2 sites in Bangladesh, Canada
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Neonatal Opioid Withdrawal Syndrome, Prenatal Opioid Exposure
Recorded Parent/Caregiver Voice for Infants With Neonatal Opioid Withdrawal Syndrome
Neonatal opioid withdrawal syndrome (NOWS) can affect a newborn infant's ability to eat, sleep, and be consoled after exposure to opioids before birth.
- Conditions
- Neonatal Opioid Withdrawal Syndrome, Prenatal Opioid Exposure, Opioid Withdrawal, Neonatal Abstinence Syndrome
- Trial name
- VOICE-NAS (NCT07864493)
- Testing
- Recorded Parent/Caregiver Voice Playback
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Pregnancy
Partnership to Improve Nutrition and Adiposity in Prenatal Clinical Care: a Pilot and Feasibility Study
This study will pilot and assess feasibility of a prenatal intervention for obese pregnant women based on the Diabetes Prevention Program (DPP).
- Trial name
- NCT02520167
- Testing
- Dietary and Lifestyle Counseling
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Premature Birth, Low Birth Weight
Pilot Trial of CenteringPregnancy With Mindfulness Skills
In the U.S., rates of preterm birth and low birth weight have increased over the past 30 years. Poor birth outcomes are especially high among racial/ethnic minority populations.
- Conditions
- Premature Birth, Low Birth Weight, Postpartum Depression
- Trial name
- NCT01646463
- Testing
- CenteringPregnancy, CenteringPregnancy with Mindfulness Skills
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cerebral Ventriculomegaly
Prospective Follow-up of a Multicentric Cohort of Children With Prenatal Discovery of Mild Isolated Cerebral Ventriculomegaly. Evaluation at 2 and 5 Years.
Isolated uni or bilateral mild cerebral ventriculomegaly represents the most frequent "minor" cerebral anomalies discovered by antenatal echography.
- Trial name
- NCT00421772
- Where
- 2 sites in France
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Fetal Alcohol Spectrum Disorders
Dissecting the Genetics of Fetal Alcohol Spectrum Disorders
The purpose of this study is to help scientists understand why some people who were exposed to alcohol in the womb have special facial features but other people do not.
- Trial name
- DiGFASD (NCT04072809)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Indiana University
Prenatal Anxiety, Depression
Prenatal Listening to Songs Composed for Pregnancy and Symptoms of Anxiety and Depression: a Pilot Study
Prenatal anxiety and depression are distressing for the expectant mother and can have adverse effects on her fetus and child. This study aimed to determine whether listening to specially composed songs would be an effective…
- Trial name
- NCT02776293
- Testing
- Relaxation, Music
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Goldsmiths, University of London
Antenatal Care, Pregnancy Related
Father Inclusive Prenatal Care Study
Young families need additional institutional support to help them meet the challenges of parenthood. Prenatal clinics are well situated to address some of their needs by expanding services to include fathers.
- Conditions
- Antenatal Care, Pregnancy Related, Parent-Child Relations, Parenting
- Trial name
- FIPC (NCT05652387)
- Testing
- Father Inclusive Prenatal Care
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Down Syndrome, Edwards Syndrome
Non-Invasive Screening for Fetal Aneuploidy
The purpose of this study is to detect whole chromosome abnormalities in maternal blood.
- Trial name
- NCT02317965
- Testing
- Maternal Blood Draw
- Where
- 10 sites in United States
- Volunteers
- 340 people
- Sponsor
- Progenity, Inc.
Cardiovascular Diseases, Heart Diseases
Prenatal Nutrition and Adult Disease
To determine whether maternal undernutrition in pregnancy is associated with differences between siblings for cardiovascular risk factors in adulthood.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Diabetes Mellitus, Non-insulin Dependent
- Trial name
- NCT00024583
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Infant, Newborn, Infant, Low Birth Weight
Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage
This large randomized trial tested whether phenobarbital given to a pregnant woman about to deliver a premature infant would prevent brain injuries in their newborns.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- Phenobarbital (NCT00009620)
- Testing
- Phenobarbital, Saline
- Where
- 11 sites in United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Pregnancy, Nausea and Vomiting in Pregnancy (NVP)
Virtual Reality (VR) Based Relaxation for Nausea and Comfort in Pregnancy
This study aims to evaluate the effect of a virtual reality (VR)-based visual relaxation intervention on nausea and vomiting severity, sleep quality, and comfort in pregnant women.
- Conditions
- Pregnancy, Nausea and Vomiting in Pregnancy (NVP), Sleep Quality, Comfort
- Trial name
- VR (NCT07503080)
- Testing
- Virtual Reality (VR) Visual Relaxation - Single Session, Virtual Reality (VR) Visual Relaxation - Three Sessions
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Filiz Keskin
Urinary Stone
2D:4D Digit Ratio and Urinary Stone Disease
This prospective observational case-control study will investigate whether the 2D:4D digit ratio is associated with urinary stone disease.
- Trial name
- NCT07736924
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Emrah Kızılay
Thalassemia, Sickle Cell Anemia
Sickle Cell Anemia Screening and Prevention in Northern Israel
Since 1987, a screening for β Thalassemia in pregnant women is carried on in northern Israel, and from 1999 all the samples were tested also for Hgb S, Hgb C, Hgb D, Hgb O Arab and others.
- Trial name
- NCT00735488
- Testing
- Observational
- Where
- Israel
- Volunteers
- 69 people
- Sponsor
- HaEmek Medical Center, Israel
Acute Respiratory Distress Syndrome, Respiratory Distress Syndrome, Acute
Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for NARDS
1. A predictive model for NARDS was established based on perinatal risk factors. Multivariate Logistic regression analysis was used to screen the independent prenatal risk factors for NARDS.
- Trial name
- NCT06188195
- Testing
- Dexamethasone
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Breastfeeding, Pain
Women Empowered Through Education to Breastfeed
The experience of breastfeeding-related pain is common for postpartum women, but is not often anticipated as part of the postpartum experience.
- Conditions
- Breastfeeding, Pain, Nipple Pain During Lactation
- Trial name
- NCT03481166
- Testing
- Education on breastfeeding pain
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Fetal Death, Fetal Anomaly
Antenatal Palliative Care
In France, according to current legislation, termination of pregnancy could be performed without any upper gestational age limit, if there is a strong probability that the fetus will be affected by a particularly severe and…
- Trial name
- SPAN (NCT03795857)
- Testing
- Semi-structured interviews
- Where
- 3 sites in France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Adolescent Pregnancy, Breastfeeding
Breastfeeding Self-Efficacy Theory-Based Education and Counseling in Pregnant Adolescents
Adolescence is the period between the ages of 10 and 19, during which individuals undergo physiological, biological, psychological, and social development, transitioning from childhood to adulthood.
- Conditions
- Adolescent Pregnancy, Breastfeeding, Self-Efficacy
- Trial name
- NCT07025265
- Testing
- reastfeeding Self-Efficacy Theory-Based Antenatal Education and Postpartum Follow-Up Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi