Clinical trials: Prenatal Condition
Fetal Hypoxia
Assessment of Cardiac Sparing in Fetal Hypoxia
The fetal heart plays a central role in the adaptive mechanisms for hypoxemia and placental insufficiency. Longitudinal data on the hemodynamic sequence of the natural history of fetal growth restriction show that the umbilical…
- Trial name
- NCT03146507
- Testing
- Ultrasound, Doppler ultrasound, Fetal echocardiography
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Assiut University
Homozygous αº-thalassemia, Hb Bart's Disease
Use of 3D/4D Ultrasound in the Evaluation of Fetal Anomalies
Volumetry measurements can be a potential clinical use as non-invasive tools in prenatal diagnosis and screening and helps to reduce the risk and complications of invasive procedures.
- Trial name
- NCT00826917
- Where
- China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Perinatal Death, Hypertension, Pregnancy-Induced
Pregnancy in the Context of Urbanicity and Climate Change. The Overall Aim of the Project is to Co-create, Implement, and Test New Clinical Guidelines in Order to Improve the Quality of Care in Antenatal Clinics in the Context of Urbanisation and Climate Change in Dar es Salaam, Tanzania.
Tanzania's population is growing quickly, and Dar es Salaam is one of the fastest-growing cities in the world. At the same time, the city is increasingly affected by very hot weather, flooding, and air pollution.
- Conditions
- Perinatal Death, Hypertension, Pregnancy-Induced, Abortion, Spontaneous, Stillbirth
- Trial name
- NCT07751432
- Testing
- CC-ANC intervention group.
- Where
- Tanzania
- Volunteers
- 1,060 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
IUGR, Fetal Growth Retardation
Cardiac Displacement From Third Trimester to Early Childhood
The aim is to increase awareness of the relationship between (IUGR) and cardiac function in the foetus, the development of cardiac function over time after delivery and what significance a possible early disturbed myocardial…
- Conditions
- IUGR, Fetal Growth Retardation, Intrauterine Growth Restriction
- Trial name
- CADETTE (NCT02583763)
- Testing
- Echocardiography, Blood sample
- Where
- 2 sites in Sweden
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Angiogenesis, Fetal Weight
Multiple Micronutrients Supplementation on Angiogenesis and Vasculogenesis Factors, and Fetal Biometry
Multiple micronutrients play an important role during pregnancy, since the decidualization and implantation phases. It has an impact on placentation and remodeling of blood vessels.
- Conditions
- Angiogenesis, Fetal Weight, Pregnancy Related, Nutrient Element Deficiency
- Trial name
- NCT06929793
- Testing
- Multiple Micronutrients, Standard Antenatal Vitamin
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Vitamin D Deficiency, Pre-Eclampsia
Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia
Vitamin D deficient pregnant ladies were selected and randomized into 2 groups for routine daily dose of multivitamin (400IU vitamin D3) versus maximum safest treatment daily dose (4000IU vitamin D3).
- Trial name
- NCT03101150
- Testing
- 400 IU Vitamin D3, 4000 IU Vitamin D3
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Pregnancy; Mental Disorders, COVID-19 Pandemic
A Telemedicine Prenatal Care Model on Low Risk Pregnants: The m@Mae-e Study
This study will compare the effectiveness of a prenatal care supported by telemedicine against usual care in low-risk pregnant women.
- Conditions
- Pregnancy; Mental Disorders, COVID-19 Pandemic, Prenatal Stress
- Trial name
- m@mae-e (NCT05745896)
- Testing
- Telemedicine appointment, Face-to-face appointment
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Talita Colombo
Oxygen Inhalation Therapy, Labour
Maternal Oxygen Administration for Fetal Distress II
Supplementary oxygen is routinely administered to patients, even those with adequate oxygen saturations, in the belief that it increases oxygen delivery.
- Conditions
- Oxygen Inhalation Therapy, Labour, Fetal Distress
- Trial name
- NCT03764696
- Testing
- tight-fitting simple facemask
- Where
- 3 sites in China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Navy General Hospital, Beijing
Pregnancy
Evaluation of a Decision Assisting Tool for Prenatal Testing
This is a randomized study of an interactive, computerized descision-assisting tool for prenatal testing decision making (PT Tool) versus standard educational booklets distributed to all pregnant women by the State of California…
- Trial name
- NCT00686062
- Testing
- Control - computerized age-appropriate prenatal testing educational brochure, PT Tool - interactive, computerized, prenatal testing decision tool
- Where
- United States
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Preterm Labor (24 GA - 32 GA)
Identification of Spontaneous Delivery Markers
The investigators project aims to identify, in pregnant women, discriminating molecules to allow an early detection of women who will spontaneously deliver prematurely, suitable in routine clinical practice.
- Trial name
- TrophY2 (NCT02225717)
- Testing
- Cervicovaginal swab
- Where
- France
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alcohol Consumption, Fetal Alcohol Syndrome Disorders
A Media Based Motivational Intervention to Prevent Alcohol Exposed Pregnancies (AEPs)
The study evaluated the effectiveness of a mail-based self-guided motivational intervention based on Project CHOICES to reduce alcohol-exposed pregnancies (AEP) with female students and non-students 18 to 44 years of age living…
- Conditions
- Alcohol Consumption, Fetal Alcohol Syndrome Disorders, Students
- Trial name
- NCT00219336
- Testing
- Self-guided Motivational Intervention, Informational Only
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Preeclampsia, Preterm Birth
Prediction of Preeclampsia and Other Pregnancy Complications Following Combined Iterative Screening
Preterm birth (PTB), preeclampsia (PE), fetal growth restriction (FGR) and intra-uterine fetal death (IUFD) constitutes the main causes of perinatal morbidity and mortality and are called "Great Obstetrical Syndromes".
- Conditions
- Preeclampsia, Preterm Birth, Fetal Growth Restriction, Intra Uterine Fetal Death
- Trial name
- PREDICTION2 (NCT03067298)
- Where
- Canada
- Volunteers
- 805 people, healthy volunteers welcome
- Sponsor
- Emmanuel Bujold
Stress, Cortisol; Hypersecretion
Effect of Maternal Cortisol Levels on Fetal Heart Rate Patterns
Objective: This study was designed to determine whether maternal cortisol levels affect fetal heart rate (FHR) patterns at third trimester. Design: Cross-sectional descriptive study.
- Conditions
- Stress, Cortisol; Hypersecretion, Fetal Heart Rate Disorder
- Trial name
- NCT05503433
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Halic University
Pregnancy Related, COVID
imPROving prenaTal carE During ConfinemenT
This study is a non-randomized, quasi-experimental, monocentric study comparing two prenatal monitoring modes in low-risk pregnancy: including at least one remote consultation (phone or teleconsultation) versus face-to-face…
- Trial name
- PROTECT (NCT04368832)
- Testing
- Remote consultation
- Where
- France
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Gestational Diabetes Mellitus (GDM), Pregnancy Induced Hypertension (PIH)
mHealth Integrated Model of Hypertension, Diabetes and Antenatal Care in India and Nepal
Our research aims to address a critical gap in the provision of quality antenatal care (ANC) in India and Nepal, by developing and evaluating an intervention comprising of a tablet-based electronic decision support system (EDSS).
- Conditions
- Gestational Diabetes Mellitus (GDM), Pregnancy Induced Hypertension (PIH), Anemia
- Trial name
- NCT03700034
- Testing
- mHealth Integrated Model of Antenatal Care
- Where
- 6 sites in India, Nepal
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation of India
Perineal Trauma, Pelvic Floor Dysfunction
Pelvic Floor Training Program and Perineal Trauma During Vaginal Birth
This study aims to determine whether a structured pelvic floor muscle training program during pregnancy can reduce perineal trauma during vaginal birth.
- Conditions
- Perineal Trauma, Pelvic Floor Dysfunction, Labor Complications, Pelvic Floor Muscle Training
- Trial name
- PFTP (NCT07292948)
- Testing
- Pelvic Floor Muscle Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mehmet Incebıyik
Sexually Transmitted Infection, HIV/AIDS
Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile)
This study aims to evaluate different screening strategies to decrease the burden of Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT) and Trichomonas vaginalis (TV) among pregnant women, and reduce adverse birth outcomes.
- Conditions
- Sexually Transmitted Infection, HIV/AIDS, Cost-effectiveness, Birth Outcomes
- Trial name
- NCT04446611
- Testing
- First antenatal care + test-of-cure, First antenatal care + week 30-34 gestation (no test-of-cure)
- Where
- South Africa
- Volunteers
- 2,247 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Birth, First, Birth Outcome, Adverse
Reducing Turkey High Cesarean Section Rates
Considering the increasing rates of cesarean delivery in Turkey, we aimed to research the impact of antenatal education on pregnancy, the childbirth process, the cesarean section rate, and the postpartum period through a…
- Conditions
- Birth, First, Birth Outcome, Adverse, Breast Feeding
- Trial name
- NCT07799545
- Testing
- Antenatal education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Preterm Rupture of Membranes
Trace Elements and Heavy Metals at PPROM
Objectives: To evaluate maternal serum trace elements and heavy metals namely, aluminum (Al), chromium (Cr), manganese (Mn), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), molybdenum (Mo), cadmium (Cd), tin (Sn)…
- Trial name
- metals&PROM (NCT04077944)
- Testing
- maternal serum concentration of trace elements and heavy metals levels
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Cengiz Gokcek Women's and Children's Hospital
Premature Rupture of Membranes
FOLCROM Trial: Foley Catheter in Rupture of Membranes
Multicenter randomized clinical trial comparing oxytocin versus oxytocin and foley catheter for induction in women who present with premature rupture of membranes who are not in labor.
- Trial name
- FOLCROM (NCT01973036)
- Testing
- Foley Catheter, Oxytocin
- Where
- 5 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic