Clinical trials: Prenatal Diagnosis
Rupture of Membranes; Premature
Amniotic Fluid Lactate in Perterm Premature Rupture of Membranes
AF lactate level could help in predicting the duration from ROM till delivery
- Trial name
- NCT03789903
- Testing
- amniotic fluid lactate
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Pregnancy, Helicobacter Pylori Infection
Effects of Dietary Heme/Non-heme Iron and Helicobacter Pylori (Hp) Infection on Maternal Iron-deficiency Anemia and Fetal Growth Outcomes
Iron deficiency is considered one of the main nutritional deficiency disorders despite the apparent availability of a high-quality diet even in developed countries, and Iron deficiency anemia (IDA) is the most common form of…
- Conditions
- Pregnancy, Helicobacter Pylori Infection, Iron-Deficiency Anemia
- Trial name
- NCT01071759
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- E-DA Hospital
Singleton-Merten Syndrome, Postnatal Complication
Prenatal US Assessment of Superior Mesenteric Vessels for Digestive Rotation
Digestive malrotation is an anatomical anomaly of the positionning of the mesenteric vessels and the digestive tract that can lead in some form to a dangerous neonatal complication: intestinal volvulus.
- Trial name
- SMA (NCT05204771)
- Testing
- Ultrasound exam, Postnatal abdominal ultrasound, Pediatric Follow up
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Pregnancy
Prenatal Exercise and Cardiovascular Health (PEACH)
Maintenance of a healthy pregnancy depends on an appropriate adaptation and responsiveness of blood vessels, to ensure appropriate blood flow to the fetus during everyday stressors.
- Trial name
- PEACH (NCT02948439)
- Testing
- Aerobic exercise
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Stillbirth
Group B Streptococcus (GBS) Associated Stillbirths in a High Burden Setting
This is a descriptive study to determine the role of fetal GBS disease as a cause for stillbirths
- Trial name
- Stillborn (NCT02339077)
- Where
- 2 sites in South Africa
- Volunteers
- 354 people
- Sponsor
- University of Witwatersrand, South Africa
Coronary Artery Disease, Atrial Fibrillation
Rivaroxaban Estimation With Warfarin in Atrial Fibrillation Patients With Coronary Stent Implantation Study (REWRAPS)
Antiplatelet therapy is indispensable for the prevention of stent thrombosis in patients who underwent coronary artery stenting.
- Conditions
- Coronary Artery Disease, Atrial Fibrillation, Stroke, Fetal Blood Loss
- Trial name
- REWRAPS (NCT02024230)
- Testing
- Rivaroxaban or Warfarin
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Fujita Health University
Wet Lung
Role of Cord Blood Hormones and Epinephrine in the Development of Transient Tachypnea of the Newborn
In this prospective, cross-sectional study, the aim was to investigate the possible role of cord stress hormones; adrenocorticotropic hormone (ACTH), cortisol, epinephrine, sT3, sT4, and thyroid-stimulating hormone (TSH) in the…
- Trial name
- NCT01149928
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Fetal Growth Retardation, Fetal Growth Complications
Acute Effects of Maternal Exercise and the Growth Restricted Pregnancy
Objectives / Specific Aims The purpose of this study is to investigate the acute effects of a single bout of moderate intensity maternal exercise on fetal well-being in a pregnancy affected by fetal growth restriction.
- Conditions
- Fetal Growth Retardation, Fetal Growth Complications, Placental Insufficiency
- Trial name
- NCT06039319
- Testing
- Physical activity
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Preterm Birth
Fetal Middle Cerebral Artery Doppler in Preterm Births Receiving Magnesium Sulfate for Neuroprotection
Two groups of women with preterm labor will be included. One will receive magnesium sulfate for neuroprotection and the other will receive placebo.
- Trial name
- NCT02506894
- Testing
- Magnesium Sulfate, 0.9% sodium chloride solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Chorioamnionitis, Puerperal Endometritis
Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term
The aims of this study are to determine whether antibiotics administered routinely in women presenting with premature rupture of membranes later than the 37+0 weeks of gestation can alter the rate of maternal and neonatal…
- Conditions
- Chorioamnionitis, Puerperal Endometritis, Neonatal Early Onset Sepsis, Neonatal Meningitis
- Trial name
- NCT01633294
- Testing
- Ampicillin + gentamicin
- Where
- Portugal
- Volunteers
- 161 people
- Sponsor
- Hospital de Santa Maria, Portugal
Perinatal Depression, Ketamine
Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression
Postpartum depression is common in mothers early after childbirth and produces harmful effects not only on mothers, but also on infants and young children.
- Conditions
- Perinatal Depression, Ketamine, Cesarean Delivery, Postpartum Depression
- Trial name
- NCT03336541
- Testing
- Ketamine
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University First Hospital
Diabetes Type 1, Diabetes Mellitus, Type 2
Antenatal Hand Milking for Pregnant Women With Diabetes'
The project is a descriptive cohort study with a retrospective and a prospective group where pregnancy and childbirth data will be studied.
- Conditions
- Diabetes Type 1, Diabetes Mellitus, Type 2, GDM
- Trial name
- NCT04794283
- Testing
- Breast milk
- Where
- Sweden
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anemia, Antenatal Care
Effects of Video-based Health Education on Maternal and Child Health in Ethiopia
Low adherence to recommended health and nutrition strategies during the critical 1000 day-window of opportunity is multifactorial but low quality communication is key limitation.
- Conditions
- Anemia, Antenatal Care, Birth Outcomes, Worm Infection
- Trial name
- MCH (NCT04414527)
- Testing
- Standard counselling, Health-Video
- Where
- Ethiopia
- Volunteers
- 675 people
- Sponsor
- University Ghent
Maternity, Birth, First
Women's Perception of Respectful Maternity Care, Birth Experiences and Perception of Traumatic Birth
The effect of the ıntrapartum care model given in line with the world health organization (WHO) recommendations on women's perception of respectful maternity care, birth experiences and perception of traumatic birth
- Conditions
- Maternity, Birth, First, Traumatic Birth, Intrapartum Fetal Distress
- Trial name
- NCT06691854
- Testing
- The group that applied the Intrapartum Care Model
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Preeclampsia, Intrauterine Growth Restriction
sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.
Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mortality in the world.
- Conditions
- Preeclampsia, Intrauterine Growth Restriction, Maternal Hypertension, Neonatal Outcome
- Trial name
- PE37 (NCT04766866)
- Testing
- sFlt1/PlGF screening in maternal blood at 35 to 36.6 weeks of gestation
- Where
- 21 sites in Belgium, Colombia and 7 more
- Volunteers
- 9,132 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Congenital Heart Defects
Use of Color Doppler in Routine Examination of Fetal Heart in Second Trimester
To evaluate the percentage of severe heart defect diagnosed with the use of color Doppler at a routine fetal scan in the second trimester of pregnancy
- Trial name
- NCT01201486
- Where
- Norway
- Volunteers
- 6,781 people
- Sponsor
- Helse Stavanger HF
Premature Rupture of Membranes
Rapid Immunoassay Tests for the Detection of Ruptured Membranes
The aim of the study is to demonstrate substantial equivalence of IGFBP-1/AFP tests with the "predicate device" Amnisure® in detecting pre labor rupture of membranes.
- Trial name
- NCT02495441
- Testing
- Use of Rapid Immunoassay Tests for the Detection of PROM
- Where
- Sri Lanka
- Volunteers
- 100 people
- Sponsor
- De Soysa Hospital for Women
Patients With Spontaneous Rupture of the Fetal Membranes
Kinetics of Inflammation Markers in Maternal Plasma: Study of the Correlation With the Diagnosis of Chorioamnionitis in Women Hospitalized for Spontaneous Rupture of the Fetal Membranes
The principal aim of this study is to help obstetricians to diagnose chorioamniotic infection early, in cases of premature rupture of the fetal membranes before 34 WA, by proposing earlier and more specific markers of infection…
- Trial name
- NCT01903759
- Testing
- Blood samples
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Type 1 Diabetes
SweMaMi DMI, Microbiome
Dysbiosis is associated with an increased risk of preeclampsia during pregnancy. The microbiome differs between those with and without type 1 diabetes and the cause of type 1 diabetes has been associated with dysbiosis.
- Trial name
- NCT04346524
- Testing
- sampling of microbiome
- Where
- 2 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Breast Feeding, Lactation Puerperal Increased
Prenatal Lactation-Focused Motivational Interviewing
Breastfeeding is good for the health of both mother and baby, but many women do not breastfeed, or do not breastfeed for as long as the participant would like.
- Conditions
- Breast Feeding, Lactation Puerperal Increased, Infant Behavior, Maternal Behavior
- Trial name
- NCT03033459
- Testing
- Motivational Interviewing, Psychoeducation Control
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- West Virginia University
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