Clinical trials: Prenatal Diagnosis
Pregnancy, Obese
The Expecting Study
The purpose of the study is to determine how a mother's health and physical activity may influence her child's growth and development.
- Trial name
- NCT02125149
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Foetus With Myelomeningocele
Prenatal Surgical Repair of Fetal Myelomeningocele
The open surgical repair of myelomeningoceles before 26 weeks gestational age provides a correction of the anomaly of Chiarri, reduces the incidence of ventriculomegaly (defined as a measure of the ventricles at the crossroads ≥…
- Trial name
- PRIUM (NCT01983345)
- Testing
- prenatal surgical repair of fetal myelomeningocele
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Twin Pregnancy, Antepartum Condition or Complication, Fetal Thymus Volume
Fetal Thymus Volume of Dichorionic Diamniotic Twin
In some studies of fetal thymus volume, fetal stress factors; infection, preterm premature premature rupture of membranes, preeclampsia, preterm delivery risk.
- Conditions
- Twin Pregnancy, Antepartum Condition or Complication, Fetal Thymus Volume, Preterm Birth
- Trial name
- NCT04055701
- Testing
- assesment of thymus volume
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Haematology
Hematological Profiles of Preterm Infants and the Impact of Antenatal Steroids
The goal of this observational study is to investigate the impact of antenatal corticosteroids (ANS) administration on haematological parameters in premature infants born to women exposed to ANS.
- Trial name
- NCT07358845
- Testing
- Antenatal Corticosteroid Exposure, Antenatal corticosteroids
- Where
- 2 sites in Poland
- Volunteers
- 1,048 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Fetal Distress, Perinatal Asphyxia
Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource Settings
The PRISM pilot feasibility study consists of two phases to determine: 1) to delivery practices, rates of primary and secondary outcomes, and feasibility of enrollment rates, and 2) to assess the feasibility and acceptability of…
- Conditions
- Fetal Distress, Perinatal Asphyxia, Birth Asphyxia, Stillbirth
- Trial name
- PRISM (NCT05946681)
- Where
- Zambia
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Maternity, Birth, First
Women's Perception of Respectful Maternity Care, Birth Experiences and Perception of Traumatic Birth
The effect of the ıntrapartum care model given in line with the world health organization (WHO) recommendations on women's perception of respectful maternity care, birth experiences and perception of traumatic birth
- Conditions
- Maternity, Birth, First, Traumatic Birth, Intrapartum Fetal Distress
- Trial name
- NCT06691854
- Testing
- The group that applied the Intrapartum Care Model
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Intrauterine Fetal Death
Uterine Doppler As StillbirthPredictor
The goal of this observational study is to define the predictive value of intrauterine fetal death for different longitudinal patterns of uterine artery Doppler indices (UtA-PI, UtA-RI and notch) from the second and third…
- Trial name
- NCT06825481
- Where
- Italy
- Volunteers
- 4,863 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Palliative Care
Memories in Heartbeats Study
A small feasibility study to explore the role of music therapy as part of memory making experiences in mothers who are experiencing a pregnancy where screening tests show that the foetus has a condition meaning they may not…
- Trial name
- NCT06259305
- Testing
- Creation of a memory track combined with the baby's heartbeat
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Malaria
Prenatal Iron and Malaria Study
The purpose of this study is to compare the presence of Plasmodium infection in parturient women who antenatally received a combination of iron-fortified foods with iron supplements versus iron-fortified foods only.
- Trial name
- PIMAL (NCT01308112)
- Testing
- iron
- Where
- Kenya
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Preeclampsia, Microvascular Function
Prenatal Aspirin and Postpartum Vascular Function
Preeclampsia is a pregnancy disorder affecting ~5-10% of pregnancies in the United States. Women who develop preeclampsia during pregnancy are more likely to develop and die of cardiovascular disease later in life, even if they…
- Trial name
- NCT05653973
- Testing
- Acetylcholine, Endothelin-1
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Growth Disorders, Intrauterine Growth Retardation
Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation
To evaluate the effect of continuous and intermittent administration of Genotonorm on stature in short prepubertal children with intra-uterine growth retardation
- Trial name
- NCT01073605
- Testing
- Genotonorm
- Where
- 31 sites in France
- Volunteers
- 208 people
- Sponsor
- Pfizer
Pre-Eclampsia, Fetal Growth Retardation
Doppler and Biological Second Trimester Placental Insufficiency Screening
To assess the role of uterine artery and maternal serum leptin and lipids and their combination in screening for pre-eclampsia and small-for-gestational-age (SGA) fetuses at 20-24 weeks of gestation
- Conditions
- Pre-Eclampsia, Fetal Growth Retardation, Placental Insufficiency
- Trial name
- ARTULEP (NCT00465634)
- Where
- France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Tours
Preterm Birth, Twin Pregnancy With Antenatal Problem
Progesterone and Cervical Pessary in Twins
The aim of this randomized control trial is to determine wheter cervical pessary plus vaginal progesterone (400mg) reduce preterm birth less than 34 weeks of gestacion and improve perinatal outcome, among women presenting…
- Trial name
- PRECEPET (NCT03058536)
- Testing
- Arabin Pessary, Vaginal Progesterone, Arabin Pessary and Progesterone
- Where
- Brazil
- Volunteers
- 312 people
- Sponsor
- Mario Henrique Burlacchini de Carvalho
Meconium Aspiration
Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration Syndrome
OBJECTIVES: Evaluate the safety and efficacy of lucinactant administered by bronchoalveolar lavage (BAL) in the treatment of meconium aspiration syndrome (MAS) in newborn infants.
- Trial name
- NCT00004500
- Testing
- Lucinactant, Standard Care
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Windtree Therapeutics
Ductus Arteriosus
The Role of Fetal Ductus Arteriosus in Predicting Spontaneous Preterm Birth
Preterm birth still remains a major cause of perinatal morbidity and mortality worldwide. The exact mechanism stimulating term and preterm births in humans is still unknown.
- Trial name
- NCT03073512
- Testing
- Ultrasound examination
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Preterm Birth, Hyperglycemia
Blood Glucose in Pregnant Non-diabetic Women During Treatment With Betamethasone for Fetal Lung Maturation
In case of threatening preterm birth, it is standard to recommend treatment with betamethasone to accelerate fetal lung maturation.
- Conditions
- Preterm Birth, Hyperglycemia, Neonatal Hypoglycemia, Threatened Preterm Labor
- Trial name
- NCT06794307
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- University of Aarhus
Prenatal Disorder
Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes
The goal of this study is to ensure that pregnant patients have the resources and support needed to access Prenatal Screening \& Diagnostic Testing (PS\&D) in an informed and evidence-based fashion by developing an innovative…
- Trial name
- OPUS (NCT06382636)
- Testing
- Standard Care, Obstetric Prenatal Genetic Testing Engagement Solution (OPUS) AI Chatbot
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- The Cleveland Clinic
Hypoplastic Left Heart Syndrome
Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome
The purpose of this research is to investigate the best way to manage evolving hypoplastic left heart syndrome (HLHS).
- Trial name
- NCT06342999
- Testing
- Fetal Aortic Valvuloplasty Procedure, Emerge Monorail and Over-The-Wire PTCA Dilatation Catheter, Trek RX and Mini Trek RX Coronary Dilatation Catheter
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mauro H. Schenone
Empowerment, Cervical Cancer, Endometrial Cancer, Follow-up, Nurse-led, PROM
An Individualised and Patient-centred Follow-up Program for Women With Gynaecological Cancer
This randomized controlled trial is testing the hypothesis that an individually focused and need-based nurse led follow-up program supported by electronic Patient Reported Outcome Measures for women with gynecological cancer will…
- Trial name
- NEMO (NCT03838861)
- Testing
- NEMO: NEw MOdel of follow-up
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- University of Southern Denmark
Fetal Growth Retardation
Doppler at the Diagnosis in Predicting Perinatal Outcomes in Early and Late-onset Fetal Growth Restriction
When a FGR is diagnose, the challenge in his monitoring is to assess the benefit-risk balance between continuing the pregnancy in order to limit complications related to prematurity and birth in order to minimize any risk of…
- Trial name
- NCT05696223
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Central Hospital, Nancy, France
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.