Clinical trials: Preoperative
Malnutrition, Surgery
Outpatient Preoperative Parenteral Nutrition in Malnourished Surgical Patients
Malnutrition is common in surgical patients. Many studies have shown a clear association between malnutrition and poor surgical outcomes.
- Trial name
- OPPortuNity (NCT03926949)
- Testing
- Parenteral Nutrition, Standard Nutrition Care
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- University of Alberta
Preoperative Care, Child
Reducing Anxiety of Children and Their Parents in the Pre-elective Surgery Process
It is emphasized in the studies that the child and parent anxiety that occurs in pediatric surgery should be prevented or reduced.
- Conditions
- Preoperative Care, Child, Parent, Anxiety
- Trial name
- NCT05538039
- Testing
- Distract with play dough, Distract with play kaleidoscope, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Isparta University of Applied Sciences
Pseudoexfoliation Syndrome
Optical Low Coherence Reflectometry Enables Preoperative Detection of Zonular Weakness in Pseudoexfoliation Syndrome
The purpose of the study was to evaluate optical ocular components in patients with pseudoexfoliation syndrome using optical low coherence reflectometry.
- Trial name
- NCT01298895
- Where
- Croatia
- Volunteers
- 224 people
- Sponsor
- General Hospital Sveti Duh
Aortoiliac Atherosclerosis, Aortoiliac Occlusive Disease
IUA Committee Research Project on the Management of TASC C and D Aortoiliac Lesions
This study aims to evaluate the clinical, imaging results of endovascular revascularization of the aorto-iliac sector in comparison with aortobifemoral bypass and the hybrid approach, in patients with atherosclerotic disease of…
- Conditions
- Aortoiliac Atherosclerosis, Aortoiliac Occlusive Disease, Aortoiliac Atherosclerosis With Gangrene, Aortoiliac Atherosclerosis Without Gangrene
- Trial name
- NCT06260475
- Testing
- Aortobifemoral bypass, aortoiliac stenting
- Where
- 2 sites in Portugal
- Volunteers
- 500 people
- Sponsor
- Universidade do Porto
Early Gastric Adenocarcinoma, Adenocarcinoma, Tubular
Effects of Oral Rabeprazole on the Prevention of Ulcer Bleeding Following Endoscopic Mucosal Resection
The purpose of this study is: To examine if oral administration of Pariet (proton pump inhibitor, 20mg tablets, twice daily for 5 days) before Endoscopic mucosal resection(EMR) exhibits preventive effects of ulcer bleeding…
- Trial name
- NCT00844675
- Testing
- rabeprazole
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- The Catholic University of Korea
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck
Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary Site
This phase II trial tests whether atezolizumab works to shrink tumors before surgery in patients with head and neck squamous cell cancer with an unknown or historic primary site that has spread to other places in the lymph nodes…
- Conditions
- Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck, Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
- Trial name
- NCT05110781
- Testing
- Atezolizumab, Radiation Therapy, Therapeutic Conventional Surgery
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, Davis
Cataract
Anesthetic and Dilating Gel for Cataract Surgery
To prepare the eye for cataract surgery, drugs must be given to the eye to allow for surgery to take place. Traditionally, dilating drops and drops containing NSAIDs (to control inflammation) are given to the patient well in…
- Trial name
- NCT00335400
- Testing
- Anesthetic Dilating Gel
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Therapy Adverse Effect
Preoperative Goal-directed Fluid Therapy and Physiological Changes Following One-lung Ventilation
Intraoperative goal-directed fluid therapy (GDFT) is proposed to improve the outcomes of patients undergoing major surgery. In the GDFT algorithm, the employment of fluid bolus plays a crucial role.
- Trial name
- NCT03064880
- Testing
- SV maximization
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Liver Transplant Disorder
Effect of 25-OH-vitamin D3 on the Liver Transplant Recipients
The low vitamin D3 levels and malnutrition before liver transplantation showed an increase in the length of stay in ICU and hospital.
- Trial name
- NCT04111146
- Where
- South Korea
- Volunteers
- 219 people
- Sponsor
- Asan Medical Center
Non-melanoma Skin Cancer, Squamous Cell Carcinoma of Skin
Same-day Versus Separate-day Preoperative Consultation for Mohs Surgery
The purpose of this study is to determine whether separate- versus same-day preoperative consultation affects time to treatment (start to finish), utilization rate of Mohs, rate of case cancellations, cost, and patient…
- Conditions
- Non-melanoma Skin Cancer, Squamous Cell Carcinoma of Skin, Basal Cell Carcinoma
- Trial name
- NCT02321982
- Testing
- Same-day preoperative consultation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pseudophakic Macular Edema, Diabetic Nephropathies
Diabetic Nephropathy, Glycemic Control and Pseudophakic Macular Edema After Cataract Surgery
This retrospective cohort study examines whether the kidney complications of diabetes (diabetic nephropathy) and blood-sugar control before surgery help predict swelling of the central retina, called pseudophakic macular edema…
- Conditions
- Pseudophakic Macular Edema, Diabetic Nephropathies, Diabetes Mellitus, Type 2, Cataract (Post-operative Cataract Surgery Follow-up)
- Trial name
- NCT07723846
- Testing
- Phacoemulsification with posterior-chamber IOL
- Where
- Thailand
- Volunteers
- 428 people
- Sponsor
- Thammasat University Hospital
Major Adverse Cardiovascular Events, Cardiovascular Testing and Consultation Intensity
How Institutional Guidelines for Urgent Inpatient Surgeries Affect Intensity of Perioperative Cardiovascular Testing
This study will evaluate the impact of implementing an educational clinical decision support (CDS) tool designed to guide perioperative cardiovascular evaluation for adults undergoing urgent inpatient surgery.
- Trial name
- NCT07692503
- Volunteers
- 3,000 people
- Sponsor
- Johns Hopkins University
Surgery
Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Subjects
Evaluate the effects of Chlorhexidine Gluconate (CHG) cloth on the reduction of bacteria on the skin.
- Trial name
- NCT02222896
- Testing
- Chlorhexidine Gluconate, Vehicle, DynaHex-2
- Where
- United States
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Medline Industries
Postoperative Complications
Impact of Oral Diets on Postoperative Fluid Collection
Patients after the surgical removal of axillary lymphnodes suffers from prolonged fluid collections. The aim of the study is to assess the impact of oral immunonutrition and high-protein diets on the reduction of fluid collection.
- Trial name
- BC1 (NCT05068882)
- Testing
- Immunonutrition, High-protein nutrition, Standard nutrition
- Where
- 2 sites in Poland
- Volunteers
- 400 people
- Sponsor
- Stanley Dudrick's Memorial Hospital
Postoperative Hypocalcemia, Postoperative Hypoparathyroidism
Ionized Calcium Changes for Predicting Postoperative Hypocalcemia After Total Thyroidectomy
This prospective observational study aims to evaluate whether changes in ionized calcium levels measured by blood gas analysis during the preoperative, intraoperative, and postoperative periods can predict postoperative…
- Conditions
- Postoperative Hypocalcemia, Postoperative Hypoparathyroidism, Total Thyroidectomy
- Trial name
- NCT07701824
- Testing
- Calcium
- Where
- Turkey (Türkiye)
- Volunteers
- 327 people
- Sponsor
- Emrecan Deniz
Propionibacterium Infection
Does the Addition of Hydrogen Peroxide to Chlorhexidine Skin Prep to Treat P. Acnes in the Shoulder
This is a prospective, randomized controlled trial to evaluate the ability of hydrogen peroxide preparation in addition to chlorhexidine to decrease the colonization of Propionibacterium acnes(a bacteria commonly found in the…
- Trial name
- NCT03656588
- Testing
- a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol, Iodine scrub and ChloraPrep alone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rothman Institute Orthopaedics
Knee Osteoarthritis
In-home Versus Hospital Preoperative Training for Patients Undergoing Total Knee Replacement
In this work the importance of the potentiation and recovery of the balance with a physiotherapeutic intervention that begins in the early preoperative phase is compared with the conventional postoperative rehabilitation.
- Trial name
- home_ATR (NCT03100890)
- Testing
- Preoperative training (hospital), Preoperative training (home)
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- University of Valencia
Breast Cancer
Monitoring Plasma Tumor DNA in Early-Stage Breast Cancer
This study is being done to see if it is possible to use blood samples to predict response to treatment in breast cancer patients receiving preoperative (or neoadjuvant) therapy.
- Trial name
- NCT02743910
- Testing
- ptDNA, Tissue sample
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Shoulder Arthroscopy, Soft Tissue Swelling
The Effect of Draping on Swelling in Shoulder Arthroscopy
Strategies to minimize soft tissue swelling during shoulder arthroscopy are constantly sought after. The investigators propose an unfamiliar method which may reduce tissue swelling during shoulder arthroscopy.
- Trial name
- NCT03216590
- Testing
- Compressive draping using adhesive incise drape
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Resectable Pancreatic Cancer, Unresectable Pancreatic Cancer
Pre-operative Treatment for Patients With Untreated Pancreatic Cancer
The purpose of this study is to determine if the combination of paclitaxel protein bound, gemcitabine, cisplatin, paricalcitol are effective in individuals with resectable and unresectable pancreatic cancer.
- Conditions
- Resectable Pancreatic Cancer, Unresectable Pancreatic Cancer, Pancreatic Adenocarcinoma, Neoadjuvant Pancreatic Cancer
- Trial name
- NCT03138720
- Testing
- Paclitaxel Protein Bound (Abraxane)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- HonorHealth Research Institute
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