Clinical trials: Preoperative
Morbid Obesity, Bariatric Surgery Candidate
Preoperative Condition in Giant Obese Patients
The frequency of super-super obese who need immediate weight loss surgery is risen continuously. For those patients a prior-to-surgery conditioning therapy is mandatory to gain technical and physical operability.
- Trial name
- NCT02616003
- Testing
- Liraglutide, Aminosteril hepa 8%, Caloric diet with 1000 kcal
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Sana Klinikum Offenbach
Surgery
Effectiveness and Costs of a Digital Versus Face-to-face Preoperative Assessment Clinic
A digital preoperative assessment clinic provides a solution for the increasing demand and declining performance on waiting times for surgery, while conducting assessments to a high standard.
- Trial name
- NCT05535205
- Testing
- Digital preoperative assessment, Face-to-face preoperative assessment
- Where
- Netherlands
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Diakonessenhuis, Utrecht
Smoking
Pilot Study: Preoperative Nicotine Lozenges
The goal of this pilot study is to determine the feasibility and potential effect size of nicotine lozenges as an adjunct to maintain brief preoperative abstinence, defined as not smoking the day of surgery.
- Trial name
- NCT00586482
- Testing
- Nicotine Lozenge, Abstinence Advisement
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Mayo Clinic
Pre Operative Sedation, Mask Acceptance
Effect of Dexmedetomidine Versus Midazolam Versus a Combination of the Two as a Premedication for Children Undergoing Bilateral Myringotomy Tube Insertion
Following an obtained written consent, a child presenting for ear tube surgery will be randomized into one of three groups for receiving a premedication.
- Conditions
- Pre Operative Sedation, Mask Acceptance, Post Operative Delerium
- Trial name
- NCT02134327
- Testing
- Combination of Dexmedetomidine with Midazolam
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Pancreas Cancer
Preoperative/Neoadjuvant Therapy and Vascular Debranching Followed by Resection for Locally Advanced Pancreatic Cancer
Pancreatic cancer continues to have a poor prognosis. Many patients are diagnosed with advanced disease. In a considerable proportion of these patients, the tumor has contact with or invades into arterial blood vessels supplying…
- Trial name
- PREVADER (NCT04136769)
- Testing
- Visceral Debranching
- Where
- 3 sites in Germany
- Volunteers
- 3 people
- Sponsor
- Ulrich Ronellenfitsch, MD
Impacted Third Molar Tooth
Evaluation of the Effects of Pre-operative Deflazacort on Post-operative Pain, Edema and Trismus
Removal of impacted lower third molar teeth is one of the most common oral surgical procedures, and these operations often lead to various complications in patients.
- Trial name
- NCT04365088
- Testing
- Deflazacort 30 MG Oral Tablet, Sugar pill
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Yuzuncu Yil University
Lung Cancer
EUS-FNA in the Pre-Operative Evaluation of Patients With Lung Cancer
This trial examines the role of EUS-FNA (Oesophageal Endoscopic Ultrasound with Fine Needle Aspiration) as an endoscopic technique for the mediastinal staging of patients with lung cancer.
- Trial name
- NCT00119470
- Testing
- EUS-FNA, Conventional Surgical Technique
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Cardiopulmonary Disease, Surgery
Focused Cardiac Ultrasound in Surgery
Mortality and morbidity remain high after non-cardiac surgery. Known risk factors include age, high ASA grade and emergency surgery.
- Conditions
- Cardiopulmonary Disease, Surgery, Morality, Complication
- Trial name
- PreOPFOCUS (NCT03501927)
- Testing
- FOCUS (focused cardiac ultrasound)
- Where
- Denmark
- Volunteers
- 337 people
- Sponsor
- Aarhus University Hospital
Rectal Cancer, Hyperthermia
The Effect of Electro-Hyperthermia in Preoperative Radiotherapy for Locally Advanced Rectal Cancer
Preoperative radiotherapy in locally advanced rectal cancer increases the possibility of complete resection and anal sphincter preservation.
- Trial name
- NCT02546596
- Testing
- Electro-hyperthermia
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Yonsei Hyperthermia Study Group
Urinary Infections, Urolithiasis
The Effect of Preoperative Culture Timing on Postoperative Outcomes of Retrograde Intrarenal Surgery
The rate of complications (unexpected situations) after retrograde intrarenal surgery is reported to be 9-25%, and the majority of these are postoperative infections.
- Trial name
- NCT06723327
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Hormone-Sensitive Breast Cancer, Breast Cancer
Randomized Phase II Study of Preoperative Letrozole (Femara) in Combination With Avastin in Hormone Receptor Positive Breast Cancer
The purpose of this study is to evaluate the objective response rate of a combination of letrozole (Femara) and bevacizumab (Avastin) given preoperatively to postmenopausal patients with hormone sensitive breast cancer.
- Trial name
- NCT00461773
- Testing
- Letrozole, Bevacizumab
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Gastrointestinal Stromal Tumor of Stomach, Submucosal Tumor of Stomach
MCB vs EUS-FNA for Preoperative Pathological Evaluation of Gastric SMT
Gastrointestinal stromal tumors (GISTs) are the most common submucosal tumors (SMTs) of the stomach. The 2022 European Society of Oncology ESMO Diagnosis and Treatment Guidelines recommend that GISTs undergo biopsy with a clear…
- Trial name
- NCT06748690
- Testing
- mucosal cutting biopsy, endoscopic ultrasound-guided-fine needle aspiration
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University People's Hospital
Bone Scintigraphy and Knee Arthroplasty
Bone Scintigraphy and Unicompartimental Knee Arthroplasty
Study the potential interest of bone scintigraphy for patients undergoing unicompartmental knee arthroplasty
- Trial name
- PUC-INTEVO (NCT03145090)
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Anxiety, Surgical Preparation, and Recovery Process in Colorectal Cancer Surgery
The Effect of Preoperative Training With Virtual Reality on Anxiety, Readiness for Surgery and Recovery Process of Patients in Colorectal Cancer Surgery
The aim of the study is to determine the effect of The Effect of Preoperative Training with Virtual Reality on Anxiety, Readiness for Surgery and Recovery Process of Patients in Colorectal Cancer Surgery.
- Trial name
- NCT07294690
- Testing
- Patients undergoing colorectal surgery will be trained using virtual reality glasses.
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Istanbul University - Cerrahpasa
Surgical Site Infection
Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances
Comparative study of antimicrobial effectiveness evaluation of of 26ml Project X, 10.5ml Project X, 5.1ml Project X and Prevantics Maxi swabstick following ASTM E1173 - Standard test method for evaluation of preoperative…
- Trial name
- NCT04218110
- Testing
- Isopropyl alcohol & Chlorhexidine Gluconate Antiseptic, Prevantics 3.15 % / 70 % Swabstick
- Where
- Romania
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Professional Disposables International, Inc.
Surgery, Nutrition Disorders
The Impact of Preoperative Supplementation of Zinc
1. Pre operative anthropometric assessment including : weight in kg, height/length and BMI 2. Pre operative Zinc supplementation (dose according to the age) for 7 days preoperatively for cases 3. Postoperative data collection
- Trial name
- NCT05785013
- Testing
- Zinc
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Cairo University
Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy
Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment
Vitreoretinal surgery for epiretinal proliferation tractional retinal detachment associated with proliferative diabetic retinopathy (PDR) is often complicated by hemorrhage from fibrovascular tissue.
- Conditions
- Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy, Tractional Retinal Detachment, Diabetic Retinopathy
- Trial name
- NCT00548197
- Testing
- Bevacizumab
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Iran University of Medical Sciences
Post-operative Pain
Comparison of Preoperative Ultrasound Guided Pectoralis Nerve Block Placement Versus Intra-operative Placement: A Prospective Randomized Trial
This study investigates the use of post-operative on-Q pain catheters for tissue expander based breast reconstruction, versus conventional ultrasound-guided blocks placed pre-operatively.
- Trial name
- NCT03201809
- Testing
- On-Q, Ultrasound guided pectoral nerve block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Bariatric Surgery Candidate, Diet Modification
Effects of Wolffia Globosa (Mankai) in Patients Undergoing Bariatric Surgery.
Candidates to bariatric surgery at The Bariatric and Metabolic Institute at Cleveland Clinic Florida are prescribed a high protein liquid diet for two weeks preoperatively and 2 weeks postoperatively.
- Trial name
- NCT03999632
- Testing
- Dietary modification with introduction of Mankai
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Cleveland Clinic Florida
Pancreatic Cancer, Complication,Postoperative
Oral Immunonutrition With Synbiotics, Omega 3 and Vitamin D in Patients Undergoing Duodenopancreatectomy for Tumoral Lesion.
The purpose of this trial is to demonstrate that synbioimmunonutrition (SI) combined with omega-3 fatty acids (O3) and Vitamin D (D) is superior to conventional 7-day preoperative immunonutrition in terms of reducing overall…
- Conditions
- Pancreatic Cancer, Complication,Postoperative, Surgery
- Trial name
- SIO3D (NCT05271344)
- Testing
- Nutritional Products
- Where
- Belgium
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
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