Clinical trials: Preoperative
Parkinson Disease
Web-based International Multi-Center Clinical Study for Parkinson's Disease
The objectives of this study are (1) to compare the clinical outcome in correlation with the electrode positions estimated by web-based image fusion of the preoperative MRI and the postoperative brain CT taken at a stable period…
- Trial name
- NCT01696812
- Testing
- electrode position
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Seoul National University Hospital
Neuroendocrine Tumors
Ki67 Proliferation Index of Pancreatic Neuroendocrine Neoplasia
This is a retrospective, monocentric study involving 50 patients with pancreatic neuroendocrine neoplasia resected between January 2008 and June 2020 at Paoli Calmettes Institute.
- Trial name
- TNE-P-Ki (NCT04753229)
- Volunteers
- 50 people
- Sponsor
- Institut Paoli-Calmettes
Malnutrition, Gastric Cancer
Efficacy of Preoperative Nutritional Support on Postoperative Outcome in Gastric Cancer Patients at Nutritional Risk by NRS-2002
Evaluation of the impact of preoperative nutritional support on clinical outcomes in patients at nutritional risk. The primary endpoint was the complication rate and the second endpoint was the length of stay.
- Trial name
- NCT01830907
- Testing
- carbohydrates, vitamins
- Where
- China
- Volunteers
- 460 people
- Sponsor
- The First Hospital of Jilin University
Elective Surgery
Preoperative Psychological Evaluation as Predictor of Outcomes
Perioperative psychological care is increasingly recognized as an essential part in the surgical environment. Previous studies have developed a strategy to evaluate the psychological influence after operations and found that…
- Trial name
- PEPO (NCT00795392)
- Testing
- ASA scale, Full-scale psychological assessment
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing Medical University
Triple Negative Breast Cancer
CMP-001 and Pre-operative Stereotactic Body Radiation Therapy (SBRT) in Early Stage Triple Negative Breast Cancer (TNBC)
This is an open-label, randomized, window-of-opportunity phase 2 clinical study evaluating the biological activity of preoperative Stereotactic Body RadioTherapy (SBRT) alone (Arm 1), and combined with subcutaneous (SC) followed…
- Trial name
- NCT04807192
- Testing
- stereotactic body radiotherapy, CMP-001
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Abdominal Aortic Aneurysm
Statin Use in Abdominal Aortic Aneurysm Repair
Aneurysm formation is associated with a chronic inflammatory response, depletion of smooth muscle cell population and excessive matrix metalloproteinases (MMPs) production.
- Trial name
- NCT01062802
- Testing
- Atorvastatin
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Hull
Malignant Neoplasm in the Head and Neck, Metastatic Malignant Neoplasm in the Head and Neck
Preoperative Embolization of Hypervascular Head and Neck Tumors to Improve Surgical Outcomes
This phase I trial tests whether embolization done prior to surgery (preoperative) will improve surgical outcomes in head and neck tumors with large amounts of blood vessels (hypervascular).
- Trial name
- NCT05490381
- Testing
- Iodixanol, Angiogram, Arterial Embolization
- Where
- United States
- Sponsor
- University of Washington
Rectal Cancer
Comparison of Preoperative and Postoperative Radiotherapy and Capecitabine in Locally Advanced Rectal Cancer
Based on the potential advantaged of preoperative chemoradiotherapy and oral fluoropyrimidine, the investigators planned a prospective randomized phase III trial which compares preoperative chemoradiotherapy and postoperative…
- Trial name
- NCT01186081
- Testing
- Preoperative chemoradiotherapy, Postoperative chemoradiotherapy
- Where
- South Korea
- Volunteers
- 240 people
- Sponsor
- Asan Medical Center
Meningitis and Sinusitis in Transnasal Surgery
Effectiveness of Preoperative Antiseptic Preparation in Transnasal Skull Base Surgery
Objective: Transnasal skull-base surgery is a complex and invasive procedure that involves the use of preoperative antiseptic preparations.
- Trial name
- NCT06313281
- Testing
- Preoperative Antiseptic preparation prior to transnasal skull base surgery
- Where
- Saudi Arabia
- Volunteers
- 142 people
- Sponsor
- King Saud University
Anxiety
The Effect of Preoperative Animated Videos on Anxiety in Patients Undergoing Hysteroscopy Without Anesthesia
Office hysteroscopy is a gynecologic procedure performed to evaluate the uterine cavity. In the majority of cases, this procedure is performed without anesthesia.
- Trial name
- NCT06625567
- Testing
- Animated video
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Soft Tissue Sarcoma of the Trunk and Extremities
Surgical Timing After Preoperative Hypofractionated Radiotherapy for Localized Extremity and Trunk Soft Tissue Sarcoma
Phase II, national, multicentric, prospective, randomized (1:1) non-inferiority trial with two parallel groups, incorporating a concurrent observational cohort of eligible non-randomized patients, designed to address critical…
- Trial name
- STARS (NCT07265661)
- Testing
- hypofractionated radiotherapy (30Gy/5 fractions) and surgical resection at 1-2 weeks after treatment, hypofractionated radiotherapy (30Gy/5 fractions) and surgical resection at 4-6 weeks after treatment
- Volunteers
- 142 people
- Sponsor
- Italian Sarcoma Group
Hypocalcemia
Effect of Preoperative High-dose Cholecalciferol in Prevention of Post-thyroidectomy Hypocalcaemia
Hypocalcaemia after thyroidectomy is observed with increasing frequency, often resulting in prolonged hospital stay with increased use of resources, delayed return to work and reduced quality of life.
- Trial name
- NCT05586529
- Testing
- Cholecalciferol
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Pak Emirates Military Hospital
Colo-rectal Cancer, Colon Cancer
Pre-Operative Treatment in REseCTable COlon CanceR
This is an open-label, randomized, controlled, multicenter, phase III study with two parallel arms. Patients with advanced colon cancer, including the upper third of the rectum, clinically staged cT3-4 and or cN+ (defined as…
- Conditions
- Colo-rectal Cancer, Colon Cancer, Colon Carcinoma
- Trial name
- NCT06899477
- Testing
- mFOLFOXIRI, mFOLFOX-6, CAPOX
- Where
- 28 sites in Germany
- Volunteers
- 714 people
- Sponsor
- Dominik Paul Modest
Anaesthesia, Anxiety
Virtual Reality (VR) Tour to Reduce Preoperative Anxiety Before Anaesthesia
Anxiety and apprehension are common among patients prior to surgery. This anxiety can lead to additional discomfort, increased pain sensation and increased stress symptoms.
- Conditions
- Anaesthesia, Anxiety, Postoperative Pain
- Trial name
- VR OP- tour (NCT04579354)
- Testing
- virtual reality tour
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- RWTH Aachen University
Pulmonary Neoplasms
Study of Preoperative Docetaxel or Cisplatin (CDDP) + Docetaxel for C-stage IB-II Non-Small Cell Lung Cancer (NSCLC)
The purpose of this study is to evaluate the safety and efficacy of the preoperative docetaxel and docetaxel-cisplatin combination in c-stage IB/II NSCLC, and select the optimal preoperative therapy for phase III trials.
- Trial name
- NCT00132639
- Testing
- Preoperative docetaxel-cisplatin combination chemotherapy, Preoperative docetaxel monotherapy
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Haruhiko Fukuda
Clear Cell Renal Cell Carcinoma, Stage II Renal Cell Cancer AJCC v8
Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial
This phase II trial tests the effect of botensilimab and balstilimab before surgery (neoadjuvant) in treating patients with high-risk clear cell renal cell cancer that has not spread from where it first started to other areas of…
- Conditions
- Clear Cell Renal Cell Carcinoma, Stage II Renal Cell Cancer AJCC v8, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8
- Trial name
- NCT07516366
- Testing
- Balstilimab, Biospecimen Collection, Botensilimab
- Where
- 5 sites in United States
- Volunteers
- 16 people
- Sponsor
- National Cancer Institute (NCI)
Early-Stage Breast Cancer
Trial to Evaluate Genomic Expression Profiles to Direct Preoperative Chemotherapy in Early Stage Breast Cancer
This multi-center randomized Phase II study assigned HER2-negative early-stage breast cancer patients to receive preoperative systemic chemotherapy in either a "genomic-guided" arm or a "non-guided arm." The "genomic-guided"…
- Trial name
- NCT00636441
- Testing
- Doxorubicin/Cyclophosphamide (AC) or Docetaxel/Cyclophosphamide (TC)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Duke University
Orthopedic Disorder
Routine Preoperative Evaluation in Surgical Patient
The "routine" pre-operative tests in healthy orthopaedic patients undergoing intermediate/ major surgery are not justified. In this study of 670 healthy orthopedic patients with 7610 preoperative tests, investigators found that…
- Trial name
- NCT04196166
- Testing
- preoperative blood tests
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Covid19, Cancer
Preoperative Shielding and N/T RT-PCR Swabbing for Elective Cancer Surgery
trial to assess the effectiveness of pre-operative screening for COVID-19 in patients undergoing elective cancer surgery.
- Trial name
- CHICANE (NCT04449783)
- Testing
- pre-operative screening, telephone consult
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Orthopedic Disorder
Effect of Preoperative Education Based on Roy Adaptation Model
This research was conducted as a randomized controlled experiment to determine the effect of the education given by the Physiological Mode of Roy Adaptation Model in patients with hip or knee arthroplasty on physical adaptation…
- Trial name
- NCT05248529
- Testing
- Education booklet
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
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