Clinical trials: Preoperative Cognitive Impairment
Postoperative Delirium, Cognitive Function Abnormal
EEG Characteristics and Postoperative Delirium
The goal of this [type of study: observational study ] is to [compare Energy differences in various bands of intraoperative electroencephalogram in elderly patients with postoperative delirium and non delirium.] in [describe…
- Conditions
- Postoperative Delirium, Cognitive Function Abnormal, PSI, Frailty
- Trial name
- NCT06102967
- Testing
- delirium
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhuo Liu
Prehabilitation
Cognitive and Physical Optimization in Prevention of Postoperative Cognitive Deficit in Elderly With Lung Resection
Postoperative cognitive deficit and its connection with surgery and general anesthesia were first mentioned in the literature in 1955 by Bradford.
- Trial name
- COGNITION (NCT06339268)
- Testing
- Cognitive training, CogniFit App
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- Military Medical Academy, Belgrade, Serbia
Cognitive Dysfunction, Cognitive Disorder, Delirium - Postoperative
the Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium
In this study, the cognitive status of the patients in the preoperative period was taken into consideration and the development of delirium after the surgery was investigated. There is no harm to the patient.
- Trial name
- NCT06597812
- Testing
- Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Amasya University
Cognitive Decline, Cognitive Impairment
Preoperative Cognitive Training for Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction (POCD) is a state of decline in cognitive ability after surgery and is frequently seen among our elderly population.
- Conditions
- Cognitive Decline, Cognitive Impairment, Cognitive Deterioration
- Trial name
- CogniTrain (NCT03353987)
- Testing
- Cognitive training
- Where
- Malaysia
- Volunteers
- 17 people
- Sponsor
- University of Malaya
Postoperative Cognitive Dysfunction
Preoperative Pain and POCD in Elderly Patients
The purpose of this study is to investigate whether preoperative pain is the risk factor of POCD in elder patients.
- Trial name
- NCT03393676
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Frailty, Perioperative/Postoperative Complications
Correlation of Preoperative Global Olfactory Function With Frailty, Perioperative Neurocognitive Disorders and Mortality
The aims of this research project are to evaluate whether global olfactory impairment is a reliable indicator of preoperative frailty and cognitive impairment, and whether it may predict postoperative neurocognitive disorders…
- Conditions
- Frailty, Perioperative/Postoperative Complications, Olfactory Disorder, Neurocognitive Disorders
- Trial name
- NCT04761458
- Testing
- Olfactory function testing, Edmonton Frail Scale, Clinical Frailty Scale
- Where
- Belgium
- Volunteers
- 215 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Gastroesophageal Cancer (GC), Postoperative Delirium (POD)
Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer
The primary objective of this observational study is to investigate the incidence of Post Operative Delirium (POD) after gastroesophageal cancer surgery.
- Conditions
- Gastroesophageal Cancer (GC), Postoperative Delirium (POD), Quality of Life (QOL), Frailty
- Trial name
- CASE (NCT06687291)
- Where
- Sweden
- Volunteers
- 130 people
- Sponsor
- Karolinska Institutet
Pain, Postoperative, Atrial Fibrillation
BRS and Outcomes in Cardiothoracic Surgery
The purpose of this study is to determine whether baroreceptor sensitivity (the ability of your body to change your heart rate and/or blood pressure in response to a situation) has any effect on how likely you are to suffer…
- Conditions
- Pain, Postoperative, Atrial Fibrillation, Cognitive Dysfunction
- Trial name
- NCT03243279
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Duke University
Postoperative Cognitive Dysfunction, Depressive Symptoms
Perioperative Cognitive Trajectories in Deferred Surgery (CoTELE-SURGE)
Cognition is the way people use their brains to think, understand, remember and make decisions. Cognitive changes are often seen even up to 1 year after surgery.
- Conditions
- Postoperative Cognitive Dysfunction, Depressive Symptoms, Postoperative Pain
- Trial name
- CoTELE-SURGE (NCT04787536)
- Testing
- Non-cardiac surgery
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- McMaster University
Postoperative Cognitive Dysfunction, Postoperative Delirium
Study of Depressive Symptoms Predicting Postoperative Cognitive Dysfunction
Postoperative cognitive dysfunction (POCD) describes a condition where cognitive functions such as attention, perception, concentration, learning, abstract thinking and problem solving are impaired postoperatively.
- Conditions
- Postoperative Cognitive Dysfunction, Postoperative Delirium, Depressive Symptoms
- Trial name
- DeprPOCD (NCT02210312)
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cognitive Impairment
Preoperative Cognitive Screening of Elderly Surgical Patients
The objectives of this pilot study are: 1. to determine whether a short cognitive test battery administered in the preadmission test center can be used to cognitively stratify elderly patients presenting for elective surgical…
- Trial name
- NCT01826825
- Testing
- Cognitive Screen, Mini-Cog
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Post Operative Cognitive Dysfunction
Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.
On pump coronary revascularization is a very common leading cause for post-operative cognitive dysfunction regarding patient age grouping and diffuse systemic inflammatory response induced by bypass machine .
- Trial name
- NCT06741566
- Testing
- intranasal saline group, intranasal insulin, Intranasal dexmedetomidine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
POCD - Postoperative Cognitive Dysfunction, Mechanical Bowel Preparation
Investigation of the Effect of Preoperative Bowel Cleansing on Postoperative Cognitive Impairment
Cognitive impairment has been reported up to 54 % after colorectal surgeries. Mechanical bowel cleansing means that a system called the second brain in the body, which includes a wide variety of genetic and neuronal structures…
- Trial name
- NCT05942404
- Testing
- mechanical bowel preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- TC Erciyes University
Cognitive Impairment
Preoperative Cognitive Screening in Older Surgical Patients Utility for Predicting Morbidity
The purpose of this work is to determine whether preoperative cognitive screening of patients over the age of 65 can be used as predictor of postoperative outcomes in patients undergoing lower extremity surgical procedures.
- Trial name
- NCT02598050
- Testing
- No Interventions as this is a observational study
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Anesthesia, Neuroinflammation
Neuroinflammatory Biomarkers After General Anesthesia: A Comparison Study
This prospective, observational study investigates the impact of repeated general anesthesia exposure on neuroinflammatory biomarkers and neurotrophic factors.
- Conditions
- Anesthesia, Neuroinflammation, Cognitive Disorders
- Trial name
- NCT07388160
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Cognitive Impairment, Preoperative Cognitive Impairment
Reliability In Neurocognitive Telemedicine Screening (RING)
Perioperative neurocognitive disorders are common after surgery and pre-existing cognitive impairment is an important risk factor.
- Conditions
- Cognitive Impairment, Preoperative Cognitive Impairment, Perioperative Neurocognitive Disorders, Neurocognitive Function
- Trial name
- NCT07760545
- Testing
- Modified Mini-Cog Telephone Assessment
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of British Columbia
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction in Elderly and it's Relation With Sleep Disorders and Melanin Concentrating Hormone
The aim of this study is to explore the relationship between preoperative sleep disorders, melanin-concentrating hormone (MCH), and delayed neurocognitive recovery early after surgery in older adult patients undergoing spinal…
- Trial name
- NCT07392840
- Volunteers
- 50 people
- Sponsor
- Minia University
Postoperative Cognitive Dysfunction
Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical Prostatectomy
Evaluation of the effect of preoperative intravenous administration of amantadine sulfate on the prevention of the development of early cognitive dysfunction in elderly patients undergoing laparoscopic radical prostatectomy
- Trial name
- NCT03988010
- Testing
- Amantadine Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- TC Erciyes University
Mild Cognitive Impairment
Preoperative Cognitive Screening of Surgical Patients 65 Years of Age or Older
The overall objectives of this study are to improve outcomes of surgical patients 65 years of age or older through risk stratification based on preoperative screening of cognition / mental function.
- Trial name
- NCT02570451
- Testing
- Patient Survey, Mini Cog, Independent Activities of Daily Living Score Sheet
- Where
- United States
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cognitive Impairment
Improving Surgical Safety of Seniors Through Preoperative Cognitive Screening
The hypothesis is that structured preoperative cognitive screening of seniors is feasible without specialized staff and can help preoperatively identify persons at high risk of complications.
- Trial name
- NCT02570438
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital