Clinical trials: Preoperative Evaluation
- Condition Preoperative Evaluation
- Funder type Industry (pharma, biotech, devices)
- Has posted results yes
Bacterial Recovery of Skin Flora Post-product Application
In Vivo Preoperative Skin Preparation Persistence Evaluation
Evaluate persistent antimicrobial effectiveness of chlorhexidine gluconate containing products on abdominal and inguinal sites following a saline and wipe challenge.
- Trial name
- NCT03155178
- Testing
- 3M CHG/IPA Prep, ChloraPrep
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Bacterial Reduction on Skin Flora Post-product Application
In-vivo Efficacy Study of Patient Pre-operative Preps
The purpose of this study is to determine the antimicrobial efficacy of the 3M CHG/IPA Prep on skin flora of the abdominal and inguinal regions of human subjects.
- Trial name
- NCT01968707
- Testing
- ChloraPrep Hi-Lite Orange, Normal saline, 3M CHG/IPA Prep Tint 10.5-mL
- Where
- United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Surgical Skin Preparation, Surgical Procedure, Unspecified
In Vivo Preoperative Skin Preparation Efficacy Study Within a Defined Product Coverage Area
This study evaluates reduction of resident flora produced by the test product within a defined prepped area of skin.
- Trial name
- NCT03681990
- Testing
- 3M CHG/IPA Prep
- Where
- Romania
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Dry Eye
A Study to Evaluate the Effect of Miebo™ on Preoperative Biometry/Keratometry and Postoperative Refractive Accuracy
A Phase 4, Multicenter, Open-Label Study to Evaluate the Effect of Miebo™ on Preoperative Biometry/ Keratometry and Postoperative Refractive Accuracy
- Trial name
- NCT06346340
- Testing
- Miebo
- Where
- 12 sites in United States
- Volunteers
- 97 people
- Sponsor
- Bausch & Lomb Incorporated
Preoperative Skin Preparation
Evaluating Safety and Effectiveness of Octenidine Dihydrochloride
The purpose of this study is to evaluate the safety and effectiveness of a topical antiseptic for preoperative skin preparation
- Trial name
- NCT03140254
- Testing
- Chlorhexidine gluconate, N,N'-(1,10-decanediyldi-1(4H)-Pyridinyl-4-ylidene)-Bis-(1-octanamine) Dihydrochloride
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Surgery
Preoperative CHG Cloth on Healthy Subjects
Evaluate the effects of CHG cloth on the reduction of bacteria on the skin.
- Trial name
- NCT02291601
- Testing
- Chlorhexidine Gluconate, Vehicle, DynaHex-2
- Where
- United States
- Volunteers
- 879 people, healthy volunteers welcome
- Sponsor
- Medline Industries
Preoperative Skin Preparation
Evaluation of the Antimicrobial Effectiveness of an Antimicrobial Cloth
Healthy volunteers will receive treatment to two body locations with the investigational product and placebo and the antimicrobial effectiveness of each treatment will be measured.
- Trial name
- NCT03229759
- Testing
- Octenidine Dihydrocloride in aqueous solution, Vehicle Control, Saline Control
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Becton, Dickinson and Company
Bacterial Recovery of Skin Flora Post-Product Application
In Vivo Patient Preoperative Skin Prep Persistence
The objective of the study is to demonstrate persistence of the CHG/IPA Prep on skin flora of the abdominal and inguinal regions of human subjects.
- Trial name
- NCT02447497
- Testing
- 3M CHG/IPA Surgical Skin Preparation - Abdominal Region, Normal Saline - Abdominal Region, 3M CHG/IPA Surgical Skin Preparation - Inguinal Region
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Aphakia, Cataract
Exploratory Study to Evaluate Uncorrected Distance Vision and Quality of Vision After Light Treatments of an Implanted RxSight Light Adjustable Lens (RXLAL) With The Light Delivery Device (LDD) in Subjects With Preoperative Corneal Astigmatism
The objective of this study is to evaluate uncorrected distance vision and quality of vision as measured by the McAlinden QoV questionnaire 3 months following the final lock-in treatment of the implanted RxSight Light Adjustable…
- Trial name
- NCT03729024
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 21 people
- Sponsor
- RxSight, Inc.
Cataract, Astigmatism
Toric Intraocular Lens Following Cataract Surgery
The objective of this clinical trial is to evaluate the safety and effectiveness of the Bausch + Lomb Toric Accommodating Posterior Chamber Silicone Intraocular Lens used to provide near, intermediate, and distance vision and a…
- Trial name
- NCT01140477
- Testing
- Toric Accommodating Lens, Accommodating Lens
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Bausch & Lomb Incorporated
Surgical Site Infection
Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances
Comparative study of antimicrobial effectiveness evaluation of of 26ml Project X, 10.5ml Project X, 5.1ml Project X and Prevantics Maxi swabstick following ASTM E1173 - Standard test method for evaluation of preoperative…
- Trial name
- NCT04218110
- Testing
- Isopropyl alcohol & Chlorhexidine Gluconate Antiseptic, Prevantics 3.15 % / 70 % Swabstick
- Where
- Romania
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Professional Disposables International, Inc.
Bacteria Microflora Reduction
Pilot Evaluation of Two Test Materials With a Positive Control When Used as a Patient Preoperative Skin Preparation
Comparative Study of Antimicrobial Effectiveness Evaluation of 26ml Project X, 5.1ml Project X and Prevantics Maxi Swabstick following ASTM E1173 - Standard Test Method for Evaluation of Preoperative, Precatheterization, or…
- Trial name
- NCT03861780
- Testing
- Project X 26ml, Project X 5.1ml, Prevantics Maxi Swabstick
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Professional Disposables International, Inc.
Surgical Skin Preparation
In-vivo Efficacy of Patient Preoperative Prep, ZuraPrep (ZP)
The objective of the study is to demonstrate the antimicrobial efficacy of the Zurex Preoperative Prep (ZuraPrep - clear) on skin flora of the abdomen and inguinal regions of human subjects.
- Trial name
- ZP (NCT03782103)
- Testing
- ZuraPrep Clear Solution, ChloraPrep, ZuraPrep Vehicle
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Surgery
Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Volunteers
Evaluate the effects of Chlorhexidine Gluconate (CHG) cloth on the reduction of bacteria on the skin.
- Trial name
- NCT02526667
- Testing
- Chlorhexidine gluconate, DynaHex-2, Vehicle
- Where
- Romania
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Medline Industries
Pain, Postoperative
Evaluation of Preoperative N1539 in Colorectal Surgery
The primary objective of this study is to evaluate the safety and tolerability of preoperative dosing of N1539 30 mg in subjects undergoing colorectal surgery, including clinical laboratory tests, wound healing evaluation…
- Trial name
- NCT03323385
- Testing
- N1539
- Where
- 10 sites in United States
- Volunteers
- 57 people
- Sponsor
- Baudax Bio
Astigmatism
Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism
The investigational enVista IOL, Model MX60Tis equipped with toric optics and axis marks on the posterior surface to minimize the possibility of surgically induced astigmatism.
- Trial name
- NCT01852084
- Testing
- enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Bausch & Lomb Incorporated
Surgery
Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Subjects
Evaluate the effects of Chlorhexidine Gluconate (CHG) cloth on the reduction of bacteria on the skin.
- Trial name
- NCT02222896
- Testing
- Chlorhexidine Gluconate, Vehicle, DynaHex-2
- Where
- United States
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Medline Industries
Skin Flora Bacterial Reduction Post-product Application
In-vivo Efficacy Study of Patient Preoperative Preps
The purpose of this study is to evaluate the antimicrobial efficacy of the 3M CHG/IPA Prep on skin flora of the abdominal and inguinal regions of human subjects.
- Trial name
- NCT01968356
- Testing
- 3M CHG/IPA Prep Colorless, 3M CHG/IPA Prep Tint, ChloraPrep
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Surgical Skin Preparation
Clinical Evaluation of Patient Preoperative Prep
The objective of the study is to demonstrate the antimicrobial efficacy of the ZP Preoperative Prep on skin flora of the abdomen and inguinal regions of human subjects.
- Trial name
- NCT02831816
- Testing
- ZuraPrep, ChloraPrep, ZP Vehicle
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Surgery
Pilot Trial of Chlorhexidine Gluconate (CHG) Preoperative Skin Preparation
Pilot study to evaluate and compare activity of CHG preoperative preparation with comparator CHG
- Trial name
- NCT02530554
- Testing
- CHG
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Medline Industries