Clinical trials: Preoperative Frailty
Frailty
Intraoperative EEG Marker of Preoperative Frailty in Elderly Patients
Frailty is a state of vulnerability, characterized by a loss of mechanisms that maintain homeostasis, determining a lower capacity for recovery in the event of a stressful incident.
- Trial name
- NCT04783662
- Testing
- Intraoperative frontal electroencephalogram
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Colorectal Cancer
Investigation of Preoperative Frailty in Elderly Patients With Colorectal Cancer and Correlation Between Preoperative Frailty and Early Postoperative Prognosis
To investigate and analyze the status of preoperative frailty and its influencing factors in elderly patients with colorectal cancer using FRALL scale and other related scales, and to explore the correlation between preoperative…
- Trial name
- NCT05915637
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Zunyi Medical College
Malnutrition; Protein, Frail Elderly Syndrome
Influence of Preoperative Nutritional Status on Perioperative Period in Cardiac Surgery in Patients With Frailty
The aim of the study is to determine whether the optimisation of the preoperative nutritional status affects the course of the perioperative period in patients with frailty.
- Trial name
- NCT05118165
- Testing
- Dietary supplement with protein
- Volunteers
- 176 people
- Sponsor
- Lithuanian University of Health Sciences
Frailty, Surgery--Complications
The PREPARE Trial: Exercise Before Surgery to Improve Recovery in Older People With Frailty
This study evaluates whether participating in a home-based exercise program leads to lower levels of complication rates and patient-reported disability after surgery.
- Conditions
- Frailty, Surgery--Complications, Disability Physical
- Trial name
- NCT04221295
- Testing
- Exercise Group
- Where
- Canada
- Volunteers
- 850 people
- Sponsor
- Ottawa Hospital Research Institute
Pancreatic Cancer, Esophageal Cancer
HOPE - A Study to Evaluate the Effect of a Prehabilitation Program on GI Cancer Patients Planning to Undergo Surgery
A one-group prospective cohort study design with measures collected pre- and post-intervention. The primary goal of this study is to evaluate the effect of a multimodal prehabilitation preoperative program on changes in frailty…
- Conditions
- Pancreatic Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- HOPE (NCT03642093)
- Testing
- Nutritional Intervention, Physical Activity Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Siobhan Trotter
Surgery, Aging
Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments
The researchers will conduct observations, interviews, and focus groups with clinicians, staff and patients of the Perioperative Optimization of Senior Health (POSH) clinic, which conducts preoperative comprehensive geriatric…
- Conditions
- Surgery, Aging, Health Care Utilization, Frailty
- Trial name
- NCT06184919
- Testing
- Process Mapping: Observations, Process Mapping: Interviews, Process Mapping: Focus Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Frailty, Perioperative/Postoperative Complications
Correlation of Preoperative Global Olfactory Function With Frailty, Perioperative Neurocognitive Disorders and Mortality
The aims of this research project are to evaluate whether global olfactory impairment is a reliable indicator of preoperative frailty and cognitive impairment, and whether it may predict postoperative neurocognitive disorders…
- Conditions
- Frailty, Perioperative/Postoperative Complications, Olfactory Disorder, Neurocognitive Disorders
- Trial name
- NCT04761458
- Testing
- Olfactory function testing, Edmonton Frail Scale, Clinical Frailty Scale
- Where
- Belgium
- Volunteers
- 215 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Gastroesophageal Cancer (GC), Postoperative Delirium (POD)
Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer
The primary objective of this observational study is to investigate the incidence of Post Operative Delirium (POD) after gastroesophageal cancer surgery.
- Conditions
- Gastroesophageal Cancer (GC), Postoperative Delirium (POD), Quality of Life (QOL), Frailty
- Trial name
- CASE (NCT06687291)
- Where
- Sweden
- Volunteers
- 130 people
- Sponsor
- Karolinska Institutet
Postoperative Acute Kidney Injury, Frailty
The Relationship Between Preoperative Frailty and Postoperative AKI and the Mediating Effect of Intraoperative BP
The primary objectives of study is to compare the difference in the incidence of postoperative AKI between frail and non-frail patients.
- Trial name
- NCT07030179
- Testing
- Frailty status
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Lanyue Zhu
Colo-rectal Cancer
NURSE-led Geriatric Assessment in Older Colorectal Cancer Patients
Older colorectal cancer patients frequently present with frailty, comorbidity, and other age-related vulnerabilities that may affect treatment tolerance and outcomes.
- Trial name
- NURSE-GA (NCT07872787)
- Testing
- Nurse-led Geriatric Assessment
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Helse Stavanger HF
Gastric Cancer, Frailty
Analysis of Influencing Factors of Preoperative Frailty in Elderly Patients With Gastric Cancer Based on the Health Ecology Theory
Frailty is common in patients with gastric cancer undergoing surgical treatment. Preoperative frailty can lead to many adverse outcomes in patients after surgery.
- Trial name
- NCT04929587
- Testing
- This is a observational research, there is no intervention
- Where
- China
- Volunteers
- 406 people
- Sponsor
- Nanjing Medical University
Delirium in Old Age, Frailty
Association of Frailty and Delirium in Elderly Hip Fracture Patients
Several studies have shown that frailty can be used as a marker for risk of adverse outcomes in elderly patients such as falls, disability, hospitalization, mortality, and can be used to predict patient clinical outcomes.
- Trial name
- NCT05246254
- Testing
- Frailty index scale
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Frailty
A Pilot Study of High Intensity Walking in Older Adults in the Pre-operative Period
The purpose of this pilot study is to evaluate a high intensity walking intervention in older surgical candidates with kidney or thoracic disease and pre-frailty or frailty.
- Trial name
- NCT04241419
- Testing
- High Intensity Walking
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Chicago
Postoperative Delirium, Cognitive Function Abnormal
EEG Characteristics and Postoperative Delirium
The goal of this [type of study: observational study ] is to [compare Energy differences in various bands of intraoperative electroencephalogram in elderly patients with postoperative delirium and non delirium.] in [describe…
- Conditions
- Postoperative Delirium, Cognitive Function Abnormal, PSI, Frailty
- Trial name
- NCT06102967
- Testing
- delirium
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhuo Liu
Lower Limb Fracture
Prognostic Value of Preoperative Frailty Assessment in Geriatric Lower Limb Orthopedic Surgery
This retrospective study evaluates the effectiveness of frailty assessment tools-specifically the Risk Analysis Index (RAI) and the 5-Item Modified Frailty Index (5-mFI)-in predicting postoperative outcomes for elderly patients…
- Trial name
- NCT07422025
- Testing
- Preoperative Frailty Scoring
- Where
- Egypt
- Volunteers
- 149 people
- Sponsor
- Benha University
Burns, Frailty
Frailty Index and Mortality After a Burn Surgery
Frailty is a condition of a reduced physiological reserve and is associated with postoperative morbidity and mortality. We evaluated the impact of preoperative frailty index (CFI) on 90-day mortality after a burn surgery.
- Trial name
- NCT05613829
- Testing
- Burn surgery
- Where
- South Korea
- Volunteers
- 1,118 people
- Sponsor
- Asan Medical Center
Pre-operative, High-risk Patient
Practice Variation in Preoperative Multidisciplinary Team Discussions
Preoperative multidisciplinary team (MDT)discussions are recommended by national and international guidelines. However, no guidance is given on how to organise and execute an MDT discussion.
- Conditions
- Pre-operative, High-risk Patient, Frailty
- Trial name
- NCT05305053
- Testing
- preoperative MDT discussion
- Where
- 9 sites in Netherlands
- Volunteers
- 225 people
- Sponsor
- Rijnstate Hospital
Frail Elderly Persons, Cardiac Surgery
A Study Protocol for Research Investigating How Geriatric Risk Assessment and Shared Decision-making Conversations Affect Treatment Decisions and Quality of Life in Patients Eligible for Open-heart Surgery.
The goal of this study is to determine whether intervention by the PRIME clinic influences cardiac treatment decisions, as well as patients quality of life and healthcare utilization.
- Trial name
- PRIME (NCT06616129)
- Testing
- Geriatric assessment, Shared decision-making conversation
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- University Medical Center Groningen
Cardiovascular Diseases in Old Age, Frailty
Virtual PREHAB Study for Patients Undergoing TAVI
Nova Scotians are aging and many are becoming frailer. People with frailty are more likely to live in worse health and do not recover well from major events, such as open heart surgery.
- Conditions
- Cardiovascular Diseases in Old Age, Frailty, TAVI
- Trial name
- NCT05617196
- Testing
- Virtual PREHAB, Standard care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Nova Scotia Health Authority
Colorectal Neoplasms, Frailty
Effect of CGA for Frail Elderly Patients Operated for Colorectal Cancer - The CRC Frailty-study
This multicentre randomized controlled trial aims to investigate whether an individualized comprehensive geriatric assessment (CGA) and care will improve postoperative results in frail elderly patients undergoing surgery for…
- Conditions
- Colorectal Neoplasms, Frailty, CGA
- Trial name
- NCT04358328
- Testing
- Comprehensive geriatric assessment (CGA) and care, Standard care
- Where
- 2 sites in Sweden
- Volunteers
- 340 people
- Sponsor
- Sahlgrenska University Hospital