Clinical trials: Preoperative Imaging Assessment
Elective Thoracic Surgery, Pulmonary Function
Deep Learning for Preoperative Pulmonary Assessment in Thoracic CT
The trial was designed as a single-centre, non-interventional prospective observational study to utilize deep learning technology combined with computed tomography (CT) images to precisely predict the pulmonary function…
- Conditions
- Elective Thoracic Surgery, Pulmonary Function, Deep Learning
- Trial name
- NCT06477458
- Testing
- Single inspiratory phase computed tomography., Respiratory dual-phase computed tomography.
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Prostate Cancer
Phase III Clinical Trial to Evaluate INR101 Injection for PET/CT Imaging in Patients With Prostate Cancer.
A multicenter, open-label, prospective Phase III clinical trial to evaluate INR101 injection for PET/CT imaging in patients with Prostate Cancer
- Trial name
- NCT06922903
- Testing
- INR101
- Where
- 32 sites in China
- Volunteers
- 240 people
- Sponsor
- Yunhe Pharmaceutical (Tianjin) Co., Ltd
Colonic Neoplasms
CT and MRI in Preoperative Colon Cancer Staging
The objective of this study is the evaluation of different imaging methods for the optimal preoperative staging of colon cancer patients.
- Trial name
- NCT05727007
- Testing
- MRI in colon cancer, CT in colon cancer
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Larissa University Hospital
Prostate Cancer (Diagnosis), ACP3
68Ga-XMFH01 PET/Fluorescence Imaging in Prostate Cancer
This study aims to evaluate the feasibility, safety, and diagnostic performance of 68Ga-XMFH01, a novel ACP3-targeted dual-modality PET and fluorescence imaging probe, for preoperative PET/CT imaging and intraoperative…
- Conditions
- Prostate Cancer (Diagnosis), ACP3, PET / CT
- Trial name
- NCT07885423
- Testing
- 68Ga-XMFH01 PET/CT
- Where
- China
- Volunteers
- 25 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Nipple Discharge
Preoperative Assessment of Pathological Nipple Discharge With Delayed Ductal Imaging of Contrast-enhanced Mammography
The goal of the prospective, interventional, self-control, open, single-center clinical study: is to evaluate the value of the delayed ductal imaging of contrast enhanced Spectral Mammography acquired in 4-6 hours after the…
- Trial name
- NCT06033573
- Testing
- contrast-enhanced spectral mammography
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Pancreatic Adenocarcinoma Resectable
Effect on Tumor Perfusion of a Chemotherapy Combining Gemcitabine and Vismodegib Before Surgery in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) has one of the worst prognoses of all human cancers and is considered as a sanctuary, resistant to most of the drugs used.
- Trial name
- NEOPACHI-001 (NCT01713218)
- Testing
- gemcitabine, Vismodegib, Neoadjuvant chemotherapy
- Where
- 2 sites in Belgium
- Volunteers
- 21 people
- Sponsor
- Jean-Luc Van Laethem
Lymph Node Metastasis, Cervical Cancer
Comparison of the Accuracy of US, MRI and PET/CT in the Assessment of LNs in Cervical Cancer.
Lymph node involvement is the most important negative prognostic factor in cervical cancer. Reliable preoperative lymph node assessment is of utmost importance to tailor the treatment.
- Trial name
- CANNES (NCT05573451)
- Testing
- ultrasound - transvaginal/transrectal + transabdominal
- Where
- Czechia
- Volunteers
- 91 people
- Sponsor
- General University Hospital, Prague
Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy
Predicting Operational Difficulties and Outcomes of RARP Based on Preoperative Assessment - Introducing the PIODO Questionnaire
The goal of this observational study is to learn about the factors that affect the course of robot-assisted radical prostatectomy and have an impact on functional and oncological outcomes in patients undergoing RARP.
- Trial name
- NCT06985004
- Testing
- PIODO Questionnaire
- Where
- Poland
- Volunteers
- 288 people
- Sponsor
- Pomeranian Medical University Szczecin
Colorectal Liver Metastases
Comparison of Primovist-enhanced MRI, Diffusion Weighted MRI and Multidetector CT of Colorectal Liver Metastases
1. Primovist-enhanced Magnetic resonance imaging (MRI) and Diffusion Weighted MRI (DW-MRI) is superior to Multidetector Computed axial Tomography (MDCT) in the detection of colorectal liver metastases.
- Trial name
- NCT01255007
- Testing
- MR imaging
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Neuro-endocrine Tumors, Small Intestine Cancer
PreOPerative Imaging of NeuroEndocrine Tumors
Neuro-endocrine tumours (NET) are the most frequent tumours of the small intestine. In spite of their small size, these tumours have the particularity of forming mesenteric metastasis and ganglionic secondary lesions along the…
- Trial name
- POPINET (NCT03958188)
- Testing
- Standardized computerized tomography (CT) reading grid for preoperative planning
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Hospices Civils de Lyon
Gastric Cancer, Para-Aortic Lymph Node Metastasis
Radiomics-Based AI Model for Predicting Para-Aortic Lymph Node Metastasis in Gastric Cancer Patients
This study aims to develop and validate an artificial intelligence (AI) model based on radiomics features extracted from preoperative CT images to predict para-aortic lymph node (PALN) metastasis in patients with gastric cancer.
- Conditions
- Gastric Cancer, Para-Aortic Lymph Node Metastasis, Lymphatic Metastasis, Preoperative Imaging Assessment
- Trial name
- NCT06947096
- Testing
- Radiomics-Based AI Imaging Analysis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Qun Zhao
Patients With a Sonographically Unclassifiable Adnexal Mass Using the IOTA Simple Rules
Value of MRI in the Characterization of Ovarian Masses Unable to Classify With Ultrasound Using the International Ovarian Tumor Analysis (IOTA) Simple Rules
Gynecological ultrasound is well known as the preferred exam to assess patients with ovarian tumors. The International Ovarian Tumor Analysis (IOTA) group developed the 'Simple Rules' to classify an ovarian tumor as benign or…
- Trial name
- IOTA-MRI (NCT02836275)
- Testing
- Diffusion/Perfusion-weighted Magnetic Resonance Imaging
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- KU Leuven
Gastric Adenocarcinoma, Stage II Gastric Cancer
Irinotecan and Cisplatin in Treating Patients Who Are Undergoing Surgery For Locally Advanced Cancer of the Stomach or Gastroesophageal Junction
This phase II trial is studying how well giving irinotecan together with cisplatin works in treating patients who are undergoing surgical resection for locally advanced cancer of the stomach or gastroesophageal junction.
- Conditions
- Gastric Adenocarcinoma, Stage II Gastric Cancer, Stage III Gastric Cancer, Stage IV Gastric Cancer
- Trial name
- NCT00062374
- Testing
- Cisplatin, Computed Tomography, Fludeoxyglucose F-18
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Cancer Institute (NCI)
Cervical Pain, Cervical Disease
The Correlation of the Cervical Symptoms With Intubation Quality and Airway Assessment
Cervical spine disorders can cause neck pain with or without neurological dysfunction. The most common cause of acute and chronic neck pain is cervical degenerative changes.
- Trial name
- NCT05188807
- Testing
- Airway ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ankara University
Carotid Artery Plaque, Diagnosis
Preoperative Identification of the Histologically "Vulnerable" Plaque Using Non-invasive Imaging, Biomechanical Assessment and Baroreflex Evaluation in Patients With Severe Carotid Stenosis
Carotid artery stenosis due to atherosclerotic plaques accounts for an important cause of ischemic stroke. Current research seeks to risk stratify asymptomatic patients by characterizing rupture-prone plaques.
- Trial name
- PREDICT (NCT05566080)
- Testing
- Carotid endarterectomy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Policlinico S. Donato
Gastroesophageal Junction Cancer
PET/MR-imaging to Differentiate Between Responders and Non-responders Receiving Preoperative Chemotherapy
The incidence of malignity in the gastroesophageal junction (GEJ) is rising in Denmark, 400 new cases annually 1. 60% of the patients with GEJ cancer have disseminated disease (M1-stage) at time of diagnosis and are consequently…
- Trial name
- NCT02433301
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Rikshospitalet University Hospital
Spinal Cord Tumors
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment
In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue.
- Trial name
- NCT05957679
- Testing
- Magnetic Resonance Elastography, Assessment and Recording
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Early Stage Breast Carcinoma
Sentinel Node Vs Observation After Axillary Ultra-souND
The hypothesis of this trial are that: avoiding axillary surgery does not worsen the outcome of patients with small breast cancer the absence of the pathological information on the risk of recurrence given by nodal status is not…
- Trial name
- SOUND (NCT02167490)
- Testing
- Arm 1: sentinel node biopsy
- Where
- 18 sites in Chile, Italy and 2 more
- Volunteers
- 1,560 people
- Sponsor
- European Institute of Oncology
Gastric Cancer, Gastroesophageal Junction Cancer
MRI and CT in Gastroesophageal Junction or Upper Gastric Adenocarcinoma
Accurate preoperative Siewert classification, precise assessment of the extent of esophageal involvement, and staging is crucial for determining the appropriate surgical approach and achieving negative resection margins.
- Trial name
- NCT06640153
- Testing
- mpMRI
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Stage IIA Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma
Pazopanib Hydrochloride Followed by Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma
This randomized pilot clinical trial studies pazopanib hydrochloride followed by chemotherapy and surgery in treating patients with soft tissue sarcoma.
- Conditions
- Stage IIA Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma
- Trial name
- NCT01446809
- Testing
- Doxorubicin Hydrochloride, External Beam Radiation Therapy, Ifosfamide
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Washington