Clinical trials: Preoperative Sedation
Anxiety, Separation
A Comparison of Two Doses of Intranasal Dexmedetomidine for Premedication in Children
The purpose of the study is to determine if 4mcg/kg of intranasal dexmedetomidine is better than 2mcg/kg in successfully sedating a child prior to induction of anesthesia.
- Trial name
- NCT02459509
- Testing
- Dexmedetomidine
- Where
- Hong Kong
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Breast Cancer
Observation of the Effect of Preoperative Use of Dexmedetomidine Hydrochloride Nasal Spray on Optimizing Awake Sedation During Breast-Conserving Surgery for Breast Cancer and Postoperative Awake Status
This clinical trial aims to evaluate the efficacy and safety of Dexmedetomidine Hydrochloride Nasal Spray for conscious sedation and anxiety relief during breast-conserving surgery.
- Trial name
- NCT07350928
- Testing
- Induction of anesthesia with dexmedetomidine nasal spray prior to surgery
- Where
- China
- Volunteers
- 394 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Anxiety
Clinical Study of Oral Midazolam Combined With Esketamine Administered Intranasally for Pediatric Preoperative Sedation
Children are prone to anxiety and even fear before surgery, and such adverse emotions may not only lead to poor induction of anesthesia, but also increase the incidence of postoperative agitation and even lead to postoperative…
- Trial name
- NCT05925283
- Testing
- Midazolam, Esketamine, midazolam and esketamine
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Anxiety
Melatonin vs Pregabalin for Anxiolysis and Sedation
preoperative melatonin, pregabalin or both will be given to all patients preoperative
- Trial name
- NCT05221151
- Testing
- Melatonin, Pregabalin, Ondansetron 4 MG
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Stage I or II Micro-invasive Oral Cancer
Preoperative Music Listening in Odontostomatological Surgery (PMLOS)
People undergoing general anesthesia for oral cancer diagnosis and treatment often experience heightened anxiety, fear and stress with negative bodily responses, such as tachycardia, hypertension, increased myocardial consumption…
- Trial name
- PMLOS (NCT05417529)
- Testing
- music therapy intervention, Standard Preparation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Preoperative Sedation
The Study is Being Conducted to Evaluate the Efficacy and Safety of Dexmedetomidine Hydrochloride Microneedles for Preoperative Sedation in Children
The study is being conducted to evaluate the efficacy, safety and the population pharmacokinetic characteristics of Dexmedetomidine Hydrochloride Microneedles for preoperative sedation in children
- Trial name
- NCT07168720
- Testing
- Dexmedetomidine hydrochloride Microneedles
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Guangzhou Novaken Pharm Co., Ltd.