Clinical trials: Preoxygenation, open to volunteers
MRI, MRI Image Enhancement
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen
The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy…
- Trial name
- NCT07135401
- Testing
- Breath-hold conditions
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
ICU Patients Under Invasive Mechanical Ventilation
Preoxygenation for Tracheal Aspirations in Intensive Care
Clearing the airways is a complex phenomenon involving the production of secretions, the nature of mucus (viscosity, elasticity, stringiness, and adhesiveness), ciliary movement, and coughing.
- Trial name
- POXTRA (NCT06421012)
- Testing
- Experimental : Patients without additional preoxygenation, Active Comparator : Patients with additional preoxygenation
- Where
- France
- Volunteers
- 2,260 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sarcopenia, Preoxygenation
Comparison of the Time to Reach End-Tidal Oxygen Value of 90 and Oxygen Reserve Index Decline Times During Preoxygenation in Sarcopenic and Non-Sarcopenic Patients
The purpose of this study is to compare the time required to reach an end-tidal oxygen (EtO2) value of 90% and the time until the Oxygen Reserve Index (ORI) drops below 0.55 during preoxygenation in sarcopenic and non-sarcopenic…
- Conditions
- Sarcopenia, Preoxygenation, Oxygen Reserve Index
- Trial name
- NCT06847672
- Testing
- preoxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Critically Ill
Feasibility of End-tidal Oxygen Concentration Monitoring During Preoxygenation for Intubation in the Intensive Care Unit.
Intubation is a common procedure in the intensive care unit. Hypoxemia is the most frequent complication of this procedure. Monitoring the end-tidal of oxygen is recommended in operating room (OR).
- Trial name
- IMPROVE-Pre (NCT05409573)
- Testing
- double monitoring of EtO2
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Hypoxemia During Surgery
Effect of Preoxygenation Position and Examination Position on Hypoxemia During Painless Gastrointestinal Endoscopy
To investigate the independent effects and interaction of pre-oxygenation position (left lateral vs left lateral with 30° head-up tilt) and examination position (left lateral vs left lateral with 30° head-up tilt) on hypoxemia…
- Trial name
- NCT07673042
- Testing
- Pre-oxygenation Position （left lateral position）, Examination Position（left lateral position ）, Pre-oxygenation Position（ left lateral head elevation in a 30-degree position）
- Where
- China
- Volunteers
- 208 people
- Sponsor
- General Hospital of Ningxia Medical University
High-flow Nasal Cannula, Oxygenation
High-Flow Nasal Oxygen for Preoxygenation in Emergency Surgery Patients With Full Stomachs
Patients with full stomachs face a high risk of regurgitation and aspiration under general anesthesia. To minimize the time between the loss of airway protective reflexes and successful tracheal intubation, rapid sequence…
- Conditions
- High-flow Nasal Cannula, Oxygenation, General Anesthesia, Induction Anesthesia
- Trial name
- HFNC (NCT06879600)
- Testing
- High-flow nasal cannula therapy application, Traditional facemask
- Where
- Vietnam
- Volunteers
- 200 people
- Sponsor
- Nguyen Dang Thu
Hypoxemic Acute Respiratory Failure
Apneic Oxygenation With High-flow Nasal Oxygenation After Preoxygenation With Noninvasive Ventilation Before Intubation in Hypoxemic Patients in Intensive Care Unit.
The aim of this clinical study is to assess whether apneic oxygenation with High-Flow Nasal Oxygen (HFNO) would decrease the incidence of severe hypoxemia compared to no apneic oxygenation during the intubation procedure (from…
- Trial name
- APNEIC (NCT07189338)
- Testing
- Apneic oxygenation, Usual Care
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Tours
Preoxygenation
Physiological Effects of Different Preoxygenation Strategies
The goal of this clinical trial is to evaluate the performance and physiological effects of different preoxygenation devices in healthy adult and pediatric volunteers (children aged 5-12 years).
- Trial name
- PREOXY II (NCT07564050)
- Testing
- Nasal cannula (NC), Non-rebreather mask (NRM), Non-rebreather mask (NRM) plus Nasal cannula (NC)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Obesity
Effect of Different-Flow High-Flow Nasal Cannula Versus Traditional Face Mask Oxygenation on Safe Apnea Time in Obese Patients
Obesity is a growing global health problem, and patients with obesity are at higher risk of hypoxemia during induction of general anesthesia.
- Trial name
- NCT07843810
- Testing
- Face Mask, High-Flow Nasal Cannula
- Where
- China
- Volunteers
- 147 people
- Sponsor
- The First People's Hospital of Lianyungang
Sarcopenia, Handgrip Strength Test
Preoperative Performance Indicators, Preoxygenation and Oxygen Reserve Relationship
The goal of this observational study is to evaluate the relationship between preoperative cardiopulmonary performance indicators and preoxygenation efficiency along with oxygen reserve depletion in patients scheduled for elective…
- Conditions
- Sarcopenia, Handgrip Strength Test, Preoxygenation
- Trial name
- NCT07688941
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent