Clinical trials: Preoxygenation
Obesity, Anesthesia
Optimal Anesthesia for Morbidly Obese Patients
Obese patients have a higher risk of anesthesia compared to the non-obese, including difficult intubation, rapid desaturation, difficult vascular access, and delayed recovery from anesthesia.
- Trial name
- NCT04395248
- Testing
- Exploring potential risk factors of difficult intubation using ultrasound, Radial artery catheterization using ultrasound guidance or blind palpation, Comparing the effectiveness of preoxygenation between high-flow nasal cannula and facemask
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Respiratory Failure
Preoxygenation in the Intensive Care Unit Using a Nose-mouth Mask Versus High-flow Nasal Cannula Oxygen.
Preoxygenation is routinely performed before endotracheal intubation. In the intensive care unit, preoxygenation is often accomplished using a nose-mouth mask.
- Trial name
- NCT01994928
- Testing
- Nose-mouth mask, High flow nasal cannula oxygen, Intubation
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Preoxygenation, Anesthesia
High-Flow Nasal Cannula (HFNC) Preoxygenation in Obese Patients Undergoing General Anesthesia
This study aims to evaluate the effectiveness of the High Flow Nasal Cannula (HFNC) for the preoxygenation of obese patients undergoing a general anesthesia.
- Conditions
- Preoxygenation, Anesthesia, Obesity
- Trial name
- NCT03615417
- Testing
- High Flow Nasal Cannula (HFNC), Standard anesthesia FaceMask (FM)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Erasme University Hospital
Rapid Sequence Induction (RSI), Preoxygenation
High Flow Oxygen in Preoxygenation During Rapid Sequence Induction in Infants and Small Children
Airway management is crucial part of the anaesthesia. There is always a considerable risk of complications or even failure during the anaesthesia induction and airway management.
- Trial name
- PRSIHFO (NCT05846919)
- Testing
- face-mask preoxygenation, HFNOC preoxygenation, HFNOC + face-mask preoxygenation
- Where
- Czechia
- Volunteers
- 4 people
- Sponsor
- Brno University Hospital
Unrecognized Condition
Preoxygenation With Optiflow™ - the Effect of Speech on Lung Oxygenation.
If a patient speaks during the process of preoxygenation with high-flow nasal oxygen via the Optiflow™ system, is the efficacy reduced as measured by end-tidal lung oxygen content?
- Trial name
- NCT03766646
- Testing
- Optiflow
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Preoxygenation
Pre-Oxygenation Techniques in Pregnancy
A trial comparing outcomes of two pre-oxygenation techniques in obstetric patients.
- Trial name
- POP (NCT03310723)
- Testing
- Face Mask preoxygenation, OptiFlow preoxygenation
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy Volunteers
A Novel Method of Preoxygenation Using a Bain Circuit
The purpose of this study is to determine whether rebreathing for a short time (a bit like breathing into a paper bag) will stimulate faster breathing and thus make the giving of Oxygen more effective.
- Trial name
- NCT00958178
- Testing
- Oxygen
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Health Service, United Kingdom
Obesity
Deep Breathing With and Without Pressure Support and PEEP for Preoxygenation in Obese Patients
Obese patients are at increased risk of low oxygen levels during the induction of general anesthesia. Preoxygenation with a face mask before anesthesia is routinely used to increase oxygen reserves.
- Trial name
- NCT07380425
- Testing
- Deep Breathing Preoxygenation, Pressure Support Ventilation, Positive End-Expiratory Pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Pamukkale University
Preoxygenation
Benefit of the Oxygen Reserve Index for Control of Success of Preoxygenation in Adults
Valuation of the probability for a correct detection of paO2 < 100 mmHg and paO2 > 200 mmHg using the Oxygen Reserve Index
- Trial name
- PRIORI (NCT04596215)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Johannes Gutenberg University Mainz
Healthy
UMOX™: A New Device for Preoxygenation
Background - Preoxygenation is performed before general anesthesia to increase the oxygen reserves of the body and prolong the safe period of apnea without hypoxia.
- Trial name
- NCT01841255
- Testing
- Mouthpiece (Umox), facemask
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Anesthesia Intubation Complication
Is Effective Preoxygenation in Elderly Patients Related to Position?
The purpose of this study is to investigate the effect of the head-up position of 20 and 30 degrees on the ETO2 reaching time of 85% and the desaturation time of 92% after intubation in elderly patients compared to the supine…
- Trial name
- NCT05659758
- Testing
- Head up positioning during preoxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Ankara City Hospital Bilkent
Hypotension on Induction
Evaluation of the Changes of Pleth Variability Index During Preoxygenation for Predicting Hypotension
The aim of this study is to investigate whether the change in pleth variation index (PVI) according to preoxygenation can predict hypotension during anesthesia induction.
- Trial name
- NCT04991220
- Testing
- Preoxygenation
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seoul National University Hospital
Obesity, Morbid
Preoxygenation With Optiflow™ in Morbidly Obese Patients is Superior to Face Mask
Optiflow™ may provide an opportunity to prolong apnea time in the morbidly obese patient population. This study will examine whether Optiflow can do this, and compare the pre-oxygenation with Optiflow to the pre-oxygenation…
- Trial name
- NCT03009877
- Testing
- Optiflow F&P 850™ System, facemask, Rocuronium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Intubation;Difficult
Preoxygenation for Difficult Airway Management
Tracheal intubation in operating room for patients at risk of difficult intubation remains a critical event. The aim of this study is to determine whether Nasal High Flow Therapy by nasal cannula Optiflow® administered before and…
- Trial name
- PREOPTI-DAM (NCT03604120)
- Testing
- Preoxygenation with high flow therapy by nasal cannula, Preoxygenation by standard Facial mask
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Nantes University Hospital
Adult Patients, Requiring Intubation
Lung MORphological Modifications Evaluated by Electrical Impedance Tomography During Preoxygenation for the Intubation of Hypoxemic Patients: Comparison of Standard Oxygenation, High Flow Nasal Oxygen Therapy, and NonInvasive Ventilation (MORPHEIT Study, an Ancillary Study of PREONIV Trial)
Prospective, randomized clinical multicentric study, in ICU, during preoxygenation for the intubation of hypoxemic patients. Electrical impedance tomographic evaluation of lung morphology variations according to the…
- Conditions
- Adult Patients, Requiring Intubation, Hypoxemia (Defined by PaO2/FiO2( Fraction of Inspired Oxygen) Below 200), Patient Covered by French Health Care System
- Trial name
- MORPHEIT (NCT03282331)
- Testing
- Standard oxygenation, High flow nasal oxygenation, noninvasive ventilation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cholelithiasis
The Effect of Preoxygenation on Gastric Decompression in Laparoscopic Cholecystectomies
Aim: Gastric insufflation caused by mask ventilation during laparoscopic surgeries may affect the surgical field, lead to regurgitation of gastric contents, and consequently cause aspiration pneumonia.
- Trial name
- NCT07274488
- Testing
- Preoxygenation, Mask Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ankara City Hospital Bilkent
Need for Intubation, No Severe Hypoxemia
Benefits of High Flow Nasal Cannula Oxygen for Preoxygenation During Intubation in Non Severely Hypoxemic Patients
The aim of this study is to determine whether High Flow nasal cannula (HFNC) oxygen is more efficient than the standard High Flow face mask (HFFM) for preoxygenation before orotracheal intubation after crash induction in non…
- Trial name
- PROTRACH (NCT02700321)
- Testing
- OPTIFLOW/ AIRVO, STANDARD Face Mask
- Where
- 8 sites in France
- Volunteers
- 192 people
- Sponsor
- Nantes University Hospital
Severe Obesity Design as BMI > 35kg/m2
Preoxygenation Optimisation in Obese Patients
Oro-tracheal intubation in operating room in obese patients with BMI > 35kg/m2 remains a critical event. The aim of this study is to determine whether Nasal High Flow Therapy by nasal cannula Optiflow® is more efficient than the…
- Trial name
- PREOPTI-POOP (NCT03106441)
- Testing
- High flow oxygen therapy by nasal cannula. Optiflow®, Facial mask oxygenation in BIPAP ventilation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Intubation;Difficult
Effectiveness of Preoxygenation With Positive Airway Pressure: a Comparison of the Supine and 25° Head up Position
Several techniques such as positive airway pressure and head-up tilt during preoxygenation have shown to prolong non-hypoxic apnea period compared to conventional technique.
- Trial name
- NCT03861949
- Testing
- 5 cmH2O CPAP, head-up position
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Hypoxemic Acute Respiratory Failure
Apneic Oxygenation With High-flow Nasal Oxygenation After Preoxygenation With Noninvasive Ventilation Before Intubation in Hypoxemic Patients in Intensive Care Unit.
The aim of this clinical study is to assess whether apneic oxygenation with High-Flow Nasal Oxygen (HFNO) would decrease the incidence of severe hypoxemia compared to no apneic oxygenation during the intubation procedure (from…
- Trial name
- APNEIC (NCT07189338)
- Testing
- Apneic oxygenation, Usual Care
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Tours