Clinical trials: Preparation for Colonoscopy
Colonoscopy
A Trial Comparing Bowel Preparation and Patient Tolerability of Miralax Versus Golytely
Prior to colonoscopies, the colon is cleansed using a laxative. Golytely is approved by the FDA for this purpose. Another laxative, called MiraLax, is approved by the FDA to relieve constipation, but it is not approved…
- Trial name
- NCT00889655
- Testing
- Golytely (polyethylene glycol), MiraLax (polyethylene glycol 3350)
- Where
- United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Colorectal Cancer Screening, Colonoscopy
Smart Phone App for COLOnoscopic PREParation
This is a randomized controlled trial designed to assess the efficacy of a novel smartphone application as an automated reminder tool in improving the quality of bowel preparation for patients undergoing outpatient colonoscopies.
- Conditions
- Colorectal Cancer Screening, Colonoscopy, Mass Screening
- Trial name
- COLOPREP (NCT03225560)
- Testing
- Bowel Preparation
- Where
- Canada
- Volunteers
- 238 people
- Sponsor
- Sunil Patel
Bowel Preparation, Colonoscopy
Validation of a Prediction Model for Inadequate Bowel Preparation
We have developed a novel inadequate bowel preparation prediction model based on a systematic review and meta-analysis. The goal of this multicenter observational study is to validate the accuracy of this model.
- Trial name
- NCT06438237
- Testing
- Bowel preparation before colonoscopy
- Where
- China
- Volunteers
- 2,360 people, healthy volunteers welcome
- Sponsor
- General Hospital of Shenyang Military Region
Colonoscopy, Colon Polyp
The Effect of 1L Polyethylene Glycol Plus Ascorbic Acid With Prepackaged Low-Residue Diet for Bowel Preparation
Background 2L polyethylene glycol plus ascorbic acid (PEGA) is known to be as effective as standard 4L polyethylene glycol for bowel preparation. However, the volume of this regimen is still large.
- Conditions
- Colonoscopy, Colon Polyp, Bowel Preparation Solutions
- Trial name
- NCT03329339
- Testing
- 1 L PEG with ascorbic acid with prepackaged, low residue diet
- Volunteers
- 200 people
- Sponsor
- Seoul National University Bundang Hospital
Bowel Preparation for Colonoscopy
Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Colonoscopy Cleansing
Magnesium salts such as magnesium citrate are often combined with polyethylene glycol to make the intestinal preparation before colonoscopy, which has shown high cleaning efficacy.
- Trial name
- NCT06728839
- Testing
- 1L PEG + 50g magnesium sulfate, 3L PEG, 4L PEG
- Volunteers
- 1,329 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colonoscopy, Predictive Model
External Validation of Models for Predicting Inadequate Bowel Preparation
In order to obtain the risk level of patients with intestinal insufficiency through simple indicators, many foreign scholars have studied and developed their own prediction models.
- Conditions
- Colonoscopy, Predictive Model, External Validation
- Trial name
- NCT04607161
- Testing
- no intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ningbo No. 1 Hospital
IBD (Inflammatory Bowel Disease), Colonoscopy
Pre-packaged Low-residue Diet for Bowel Preparation in Patients With Inflammatory Bowel Disease
The primary objectives of this project are twofold: firstly, to evaluate the role of Maifu Changqing® Complete Nutrition Formula Powder in bowel preparation for colonoscopy in patients with IBD; and secondly, to enhance the…
- Conditions
- IBD (Inflammatory Bowel Disease), Colonoscopy, Colonoscopy: Bowel Preparation
- Trial name
- NCT07353853
- Testing
- pre-packaged low-residue diet for bowel preparation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Changhai Hospital
Bowel Preparation
Compare the Effectiveness of Sports Drink and Water as a Solvent in Polyethylene Glycol for Colonoscopy
In this study, 200 patients were enrolled from 2023.1.1 to 2023.12.31, and were randomly divided into intervention and control groups.
- Trial name
- NCT05542810
- Testing
- Use sports drinks as polyethylene glycol solvents
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- GanHuoye
Chronic Kidney Diseases, Colon Polyp
Low-volume vs High-volume Polyethylene Glycol Based Bowel Preparation for Colonoscopy in People Receiving Hemodialysis
Current American Society for Gastrointestinal Endoscopy (ASGE) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines recommend a split regimen of high-volume (4-liter polyethylene glycol-based preparation) or…
- Conditions
- Chronic Kidney Diseases, Colon Polyp, Dialysis; Complications, Colon Cancer
- Trial name
- PrepDial (NCT04709770)
- Testing
- 2-liters polyethylene glycol with citrate and simethicone, 4-liters polyethylene glycol with simethicone, Low-residue diet
- Volunteers
- 264 people
- Sponsor
- Alfredo Di Leo
Bowel Preparation Solutions, Colonoscopy
Efficacy, Tolerance and Safety of Split Dose Bowel Preparation for Colonoscopy: 4L Polyethylene Glycol (PEG) Versus 1L Polyethylene Glycol Plus Sodium Picosulfate-magnesium Citrate (SPMC)
4L split dose PEG is the gold standard for bowel preparation, however it comes with poor tolerability and poor compliance. Combination of PEG with different agent is useful in reducing total volume, improving compliance and…
- Trial name
- NCT04474002
- Testing
- 4L Klean Prep®, 1L Klean prep® and 2 sachets Picoprep®
- Where
- Hong Kong
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Colo-rectal Cancer, Colon Lesion
Compare the Patient Satisfaction and Effectiveness After Novel Application-based or Conventional Health Education of Bowel Preparation for Colonoscopy
Colorectal cancer is the cancer with highest incidence in Taiwan. The disease itself and subsequent treatment cause huge impact on the physical, psychological, and spiritual parts and social role of a patient.
- Trial name
- NCT06560671
- Testing
- novel type of health education
- Where
- Taiwan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Polyethylene Glycol, Cathartics
Development and Validation for Predicting Inadequate Bowel Preparation
High-quality colonoscopy is considered the gold standard for the detection and prevention of colorectal cancer, and its efficacy is predicated on optimal colon cleansing.However, about 18%-35% of patients were still reported to…
- Conditions
- Polyethylene Glycol, Cathartics, Colonoscopy
- Trial name
- NCT04290715
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,644 people
- Sponsor
- Ningbo No. 1 Hospital
Bowel Preparation for Colonoscopy
Efficacy of Low-residue Full Nutritive Formula Powder in Bowel Preparation for Colonoscopy
Previously, our team compared the effects of a low-residue full nutrition formula podwer (FNFP) combined with 3 liters of polyethylene glycol(PEG) solution and the self-prepared low-residue diet combined with 3 liters of PEG…
- Trial name
- NCT06514989
- Testing
- Low-residue full nutrition formula podwer, Self-prepared low-residue diet
- Where
- 27 sites in China
- Volunteers
- 757 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colonoscopy, Bowel Preparation
Evaluation of an Oral Sodium Sulfate Solution for Patients With Prior Difficult or Incomplete Cleansing
This case series aims to evaluate the effectiveness and tolerability of Oral Sulfate Solution (OSS) in patients who had previously experienced poor colonoscopy preparation.
- Trial name
- OSS (NCT06051955)
- Testing
- oral sodium sulfate
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Lawrence Charles Hookey
Healthy Person, Bowel Preparation Before Colonoscopy
Comparison Between 2L Coolprep® and Combination of 1L Coolprep® and Bisacodyl as Bowel Preparation
comparison of the use of Colyte® (ascorbic acid mixed polyethylene glycol solution) in two-liter versus one-liter volume and pretreatment with bisacodyl for colonoscopy preparation.
- Trial name
- NCT01745835
- Testing
- 2L Coolprep®, 1L Coolprep® and Bisacodyl
- Where
- South Korea
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colon Disease
Comparison of Oral Lactulose Versus Polyethylene Glycol for Bowel Preparation
Adequate quality of bowel preparation(BP) is essential for colonoscopy. Several guidelines recommend that split-dose of 4L PEG should be used as a standard regime for BP.
- Trial name
- NCT04794049
- Testing
- Lactulose, Polyethylene Glycol (PEG)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Colonoscopy, Hospitalized Patients
1L- vs. 4L-PEG for Bowel Preparation Among Inpatients.
Background and aims: Inpatients are at high risk for inadequate colon cleansing. Experts recommend 4L-polyethylene-glycol (PEG) solution because of its effectiveness and safety profile.
- Conditions
- Colonoscopy, Hospitalized Patients, Bowel Preparation
- Trial name
- NCT04310332
- Testing
- 1L-PEG, 4L-PEG
- Where
- 10 sites in Italy
- Volunteers
- 1,004 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Colorectal Cancer
Efficacy and Tolerability of Suprep With and Without Simethicone for Routine Colonoscopy for Colorectal Cancer Screening
The purpose of this study is to investigate Suprep bowel preparation, with and without the anti-gas medication simethicone, in terms of efficacy and patient tolerability in the preparation of patients undergoing routine…
- Trial name
- NCT02523911
- Testing
- Simethicone, sodium sulfate/potassium sulfate/magnesium sulfate solution
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MercyOne Des Moines Medical Center
Thirst, Bowel Preparation for Colonoscopy
Administration of a 'Thirst Relieve Kit' Versus Placebo in Patients After Hospital-based Bowel Preparation for Colonoscopy and Assessment of Thirst Intensity
The goal of this study is to evaluate whether a "thirst kit" (lemon popsicle) is effective in reducing thirst intensity in patients undergoing hospital bowel preparation for colonoscopy.
- Conditions
- Thirst, Bowel Preparation for Colonoscopy, Colonoscopy
- Trial name
- NCT07699809
- Testing
- lemon popsicle, Water blister pack
- Where
- Brazil
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Bowel Preparation
A Predictive Model for Inadequate Bowel Preparation
We aimed to develop a predictive model of inadequate bowel preparation and to further validate it by a randomized controlled trial.
- Trial name
- NCT03704571
- Testing
- Polyethylene Glycol
- Where
- China
- Volunteers
- 429 people
- Sponsor
- Shandong University