Clinical trials: Presbyacusis
Hearing Loss, Presbycusis
Variability In Hearing Aid Outcomes In Older Adults
The goal of this project is to find out if the way a hearing aid processes a sound signal should be determined in part by an individual's cognitive characteristics.
- Trial name
- NCT02448706
- Testing
- Hearing Aid Fitting A, Hearing Aid Fitting B
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Northwestern University
Siderosis, Neurological Disorder
Audiovestibular Function in Infratentorial Superficial Siderosis
One in six people in the United Kingdom and over 400 million people worldwide have disabling hearing loss. This figure will double by 2050 as predicted by the World Health Organisation.
- Conditions
- Siderosis, Neurological Disorder, Rare Diseases, Age Related Hearing Loss
- Trial name
- AViSS (NCT04200664)
- Testing
- Hearing assessment, Vestibular/balance assessment, Quality of life assessment
- Where
- 2 sites in United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University College, London
Age Related Hearing Loss, Deafness
A Clinical Trial of the Safety and Efficacy of TJ0113 Capsules in the Treatment of Patients With Age-related Hearing Loss
The purpose of this study is to explore the safety and efficacy of TJ0113 capsules in patients with age-related hearing loss.
- Trial name
- NCT07012746
- Testing
- TJ0113 capsules
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yilai Shu
Dementia, Hearing Loss
Evaluation of the Impact of Cochlear Implants on Cognition in Older Adults
The subjects will be age 65 years and older, with no upper limit of age range with hearing loss that are candidates for standard-of-care cochlear implant.
- Conditions
- Dementia, Hearing Loss, Presbycusis
- Trial name
- NCT02729402
- Testing
- Cognitive Testing
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Utah
Progesterone, Estrogens
Neural Changes in the Aging Auditory System
The purpose of this study was to determine the effects of hormone replacement therapy (HRT) on hearing in post-menopausal women.
- Conditions
- Progesterone, Estrogens, Hearing, Psychoacoustics
- Trial name
- NCT00264407
- Testing
- Hormone Replacement Therapy - HRT
- Where
- 2 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Hearing Loss, Hearing Loss, Age-Related
Sight and Hearing Investigation Into Effects on Delirium
The goal of this observational study is to learn about sensory loss in hospital patients with delirium. The main questions it aims to answer are: Are hearing and vision loss related to increased risk of having delirium? Do…
- Conditions
- Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium
- Trial name
- SHIELD (NCT06176625)
- Testing
- Communication Signage, Amplifier Use
- Where
- United States
- Volunteers
- 1,543 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Presbycusis, Bilateral, Alzheimer Disease 2 Due to Apoe4 Isoform
Hearing Aid and Individuals With Cognitive Disorders
This is a pilot study with the aim of evaluating the feasibility of the procedures of a future clinical trial that will help determine the impacts of hearing aid interventions on older patients with Alzheimer's Disease and…
- Conditions
- Presbycusis, Bilateral, Alzheimer Disease 2 Due to Apoe4 Isoform, Mild Cognitive Impairment
- Trial name
- NCT04049643
- Testing
- Audiologist-based fitting, Service-only Fitting, Device-only fitting
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Yu-Hsiang Wu
Age-related Hearing Loss, Dementia
Management of Age-Related Auditory Decline and Early Warning of Its Co-occurring Dementia
Against the backdrop of global population aging, age-related hearing loss (ARHL) has reached epidemic proportions and is increasingly recognized as an independent risk factor for cognitive decline and other major…
- Trial name
- AHEAD (NCT07608640)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Hearing Loss, Adult-Onset, Hearing Loss, Age-Related
Hearing Healthcare Assessment in Rural Communities
Adult hearing loss in is the third most common chronic health condition in the United States. Adults living in rural areas face a higher risk of experiencing hearing loss, and more difficulty receiving testing and treatment than…
- Trial name
- HHARC (NCT05786794)
- Testing
- Patient Navigation Program for Hearing Health Care
- Where
- 9 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Matthew Bush, MD
Hearing Loss, Age-Related
Early Identification of Age-related Hearing Impairment
The need for future hearing rehabilitation is enormous. World Health Organization (WHO 2021) has estimated that by 2050, 2.5 billion people will have some degree of hearing loss, and 1/4 of them will require hearing…
- Trial name
- NCT06418321
- Testing
- Investigational device, Audiometer, Otomicroscopy
- Where
- 2 sites in Finland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Aalto University
Hearing Loss, Age-Related, Speech Intelligibility
Benefits of Choir for Older Adults With Unaddressed Hearing Loss (WP2)
Unaddressed age-related hearing loss is highly prevalent among older adults, typified by negative consequences for speech-in-noise perception and psychosocial wellbeing.
- Conditions
- Hearing Loss, Age-Related, Speech Intelligibility, Psychosocial Functioning
- Trial name
- NCT06580847
- Testing
- Group Singing, Audiobook Club
- Where
- 7 sites in United States, Australia and 3 more
- Volunteers
- 210 people
- Sponsor
- Toronto Metropolitan University
Age-related Hearing Loss, Age-related Cognitive Decline
Cognitive Function and EEG Brain Network Remodeling Among Users of Hearing Aids With ARHL
This study intends to retrospectively collect and analyze the case data of patients with age-related hearing loss who were admitted to the Otolaryngology Department of Sun Yat-sen Memorial Hospital from January 2020 to June 2024.
- Conditions
- Age-related Hearing Loss, Age-related Cognitive Decline, Depression, Sleep Disturbance
- Trial name
- EEG/ARHL (NCT06893432)
- Testing
- hearing aids
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Age-related Hearing Loss
Hearing Loss and Communication Needs in a Group Care Setting for Older Adults
The purpose of this study is to develop and test a multicomponent hearing care intervention for the PACE staff members in order to learn more about communication and engagement.
- Trial name
- NCT04659967
- Testing
- Virtual Training
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Alzheimer Disease, Hearing Loss
Early Age-Related Hearing Loss Investigation (EARHLI)
Early Age-Related Hearing Loss Investigation (EARHLI) is a single site study that will randomize late middle age adults to either a hearing intervention (including hearing aids) or a health education intervention.
- Conditions
- Alzheimer Disease, Hearing Loss, Cognitive Impairment
- Trial name
- EARHLI (NCT06174038)
- Testing
- Hearing Intervention, Health Education Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Hearing Loss, Deafness and Auditory Perception
Effects of Cognitive Training on Speech Perception
In this study, the investigators are testing whether cognitive training can lead to improvements in speech perception for individuals with hearing loss.
- Trial name
- NCT02294812
- Testing
- Cognitive training
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Aaron Newman
Presbycusis
Longitudinal Outcomes of Hearing Aids
Age-related hearing loss is a substantial national problem due to its high prevalence and significant psychosocial consequences.
- Trial name
- NCT04030299
- Testing
- Over-the-counter fitting
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Yu-Hsiang Wu
Hearing Loss, Age-Related, Presbycusis, Bilateral
Assessment of e-Audiology for Providing Clinical Services and Support
Technological advances in hearing aids and telecommunications, including the widespread availability of telehealth (referred to in this proposal as "e-Audiology") applications, have the potential to expand both access and…
- Conditions
- Hearing Loss, Age-Related, Presbycusis, Bilateral, Hearing Disability
- Trial name
- eAudiology (NCT04048460)
- Testing
- Delivery of hearing healthcare through eAudiology application
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of South Florida
Age-related Hearing Loss, Presbycusis
Genetic Study of Age Related Hearing Loss
Age-related hearing loss, or presbyacusis, is one of the most common chronically handicapped conditions for the elderly. Many factors including genetics, diet, diseases, drugs, socioeconomic factors and environmental variables…
- Trial name
- ARHL (NCT01732289)
- Testing
- genes
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Alzheimer Disease, Presbycusis
Clinical Trial on Alzheimer Disease, Presbycusis and Hearing Aids
This is a 12-months' randomized clinical trial that aims at studying the benefit of bilateral hearing aids in hearing impaired patients suffering from a slight to moderate stage Alzheimer disease.
- Trial name
- NCT00488007
- Testing
- Hearing aids used : PHONAK Savia and Valeo
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
Hearing Loss, Age-Related, Hearing Aids
Communication Training in Hearing Aid Users
The objective of the current research project is to investigate the effectiveness of communication training in first-time hearing aid users with mild to moderate hearing loss delivered in-person in groups or individually.
- Conditions
- Hearing Loss, Age-Related, Hearing Aids, Sensorineural Hearing Loss, Speech Intelligibility
- Trial name
- NCT07798453
- Testing
- Cognitive screening, Audiological Assessment, Questionnaires
- Where
- Belgium
- Volunteers
- 57 people
- Sponsor
- University Ghent