Clinical trials: Presbyopia,
Presbyopia
Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia
Safety and efficacy of POS in participants with presbyopia
- Trial name
- VEGA-3 (NCT06542497)
- Testing
- 0.75% phentolamine ophthalmic solution
- Where
- 39 sites in United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Opus Genetics, Inc
Visual Acuity, Presbyopia
Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses
This is a 6-visit, single-masked, multi-site, 2×3 crossover, randomized-controlled, dispensing clinical trial to evaluate visual acuity.
- Trial name
- NCT07076160
- Testing
- INFUSE® One Day Multifocal, ACUVUE® OASYS MAX 1-Day Multifocal Contact Lens
- Where
- 7 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia
Experienced soft contact lens wearing subjects will be enrolled in this 1-week, confirmatory, randomized, bilateral, 2-way crossover, double masked (subject and investigator), repeated measures, dispensing study.
- Trial name
- NCT05325931
- Testing
- kalifilcon A Daily Disposable Multifocal, samfilcon A for Presbyopia
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia
Safety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With Presbyopia
The objectives of this study are: To evaluate the safety and efficacy of Nyxol alone and with adjunctive low dose pilocarpine to improve distance-corrected near visual acuity (DCNVA) in subjects with presbyopia.
- Trial name
- VEGA-2 (NCT05646719)
- Testing
- Phentolamine Opthalmic Solution 0.75%, Low dose pilocarpine, Low dose pilocarpine vehicle
- Where
- 26 sites in United States
- Volunteers
- 333 people
- Sponsor
- Opus Genetics, Inc
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study B
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06401551
- Testing
- CPO Pro IOL, CPO IOL, Cataract Surgery
- Where
- 8 sites in United States
- Volunteers
- 71 people
- Sponsor
- Alcon Research
Aphakia, Astigmatism
Evaluation of Long-term Safety and Performance of PanOptix Trifocal Intraocular Lens (IOL)
The purpose of this Post-Market Clinical Follow-up (PMCF) study is to describe the long-term safety and performance of the AcrySof IQ PanOptix IOL toric and non-toric models in subjects bilaterally implanted with these IOLs for 3…
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT06166901
- Testing
- AcrySof IQ PanOptix IOL Toric, AcrySof IQ PanOptix IOL Non-Toric
- Where
- 7 sites in Spain
- Volunteers
- 211 people
- Sponsor
- Alcon Research
Presbyopia Condition
A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)
The goal of this clinical trial is to learn if the contact lens we are testing will work to extend the range of clear focus at distance to provide an increase in clear vision at closer ranges without the additional need for…
- Trial name
- EDOF (NCT06698731)
- Testing
- Test lens, Control lens
- Where
- 3 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Presbyopia
Clinical Performance of a Phakic Intraocular Lens (IOL)
This study will evaluate the clinical performance of a phakic intraocular lens (IOL) for the improvement of Uncorrected Near Visual Acuity (UCNVA) in subjects who require between +1.00 and +2.50 Reading Add.
- Trial name
- NCT03499821
- Testing
- EDOF ICL
- Where
- 6 sites in Belgium, Spain
- Volunteers
- 41 people
- Sponsor
- Staar Surgical Company
Presbyopia, Astigmatism
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
The purpose of this study is to evaluate on-eye clinical performance of the investigational contact lenses following 30 days of wear in the intended population.
- Trial name
- NCT06461455
- Testing
- Lehfilcon A multifocal for astigmatism contact lenses, Samfilcon A multifocal for astigmatism contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
- Where
- 11 sites in United States
- Volunteers
- 95 people
- Sponsor
- Alcon Research
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study A
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06400745
- Testing
- CPO Pro IOL, CPO IOL, Cataract surgery
- Where
- 8 sites in United States
- Volunteers
- 87 people
- Sponsor
- Alcon Research
Presbyopia
Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia
The objectives of this study are: To evaluate the efficacy of Nyxol + Pilocarpine to improve DCNVA in subjects with presbyopia
- Trial name
- NCT04675151
- Testing
- Phentolamine Ophthalmic Solution 0.75%, Pilocarpine
- Where
- 17 sites in United States
- Volunteers
- 150 people
- Sponsor
- Opus Genetics, Inc
Presbyopia
Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
The purpose of this study is to evaluate the on-eye multifocal clinical performance of investigational LID233309 contact lenses and Oasys multifocal (MF) contact lenses in a daily wear dispensing trial.
- Trial name
- NCT06469242
- Testing
- Serafilcon A multifocal contact lenses, Senofilcon A multifocal contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
- Where
- 8 sites in United States
- Volunteers
- 106 people
- Sponsor
- Alcon Research
Astigmatism, Presbyopia
A Clinical Comparison of Two Multifocal Toric Soft Contact Lenses
This study aims to compare the short-term clinical performance of the two study contact lenses.
- Trial name
- NCT06438601
- Testing
- Lens A (omafilcon A), Lens B (comfilcon A)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Refitting Multifocal Contact Lens Wearers With a Different Multifocal Contact Lens
The purpose of this study was to compare ease of handling and vision acuity of two multifocal contact lenses to correct presbyopia that are currently CE marked and on the UK market.
- Trial name
- NCT06328660
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia
An Evaluation of the Safety of CSF-1 in Presbyopic Subjects
This is a multi-center, double-masked, vehicle-controlled study. The purpose of the study is to evaluate the safety of CSF-1 compared with vehicle in presbyopic subjects. Subjects will be treated for at least 6 weeks.
- Trial name
- NCT05393895
- Testing
- CSF-1, Vehicle
- Where
- 12 sites in United States
- Volunteers
- 178 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Presbyopia
Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens
This study is a randomized, single-masked, crossover clinical trial. There are two study lenses. Each lens will be dispensed for 3 ± 1 days and then an optimization visit will occur.
- Trial name
- NCT04189224
- Testing
- JJV Investigational Multifocal Contact Lens, 1-Day Acuvue® Moist Brand Multifocal Contact Lens
- Where
- 4 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types
To evaluate and compare the performance of two monthly replacement multifocal contact lenses in existing wearers.
- Trial name
- NCT06232590
- Testing
- Control Lens (comfilcon A), Test Lens (lehfilcon A)
- Where
- 5 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia, Myopia
Clinical Investigation iDesign System With 1.3-PRESBY Treatment and STAR S4 IR™ Excimer Laser System
A prospective study to evaluate the feasibility of a new treatment algorithm to increase depth of focus after wavefront-guided LASIK correction of myopic refractive errors with the iDesign Advanced Wavescan Studio™ System and…
- Trial name
- NCT02806726
- Testing
- iDesign 1.3-PRESBY treatment, iDesign 1.3 treatment
- Volunteers
- 42 people
- Sponsor
- Abbott Medical Optics
Aphakia, Cataract
A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus
The primary objective of this study is to evaluate, for the visual correction of aphakia and presbyopia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) to provide an extended depth of focus (improve…
- Conditions
- Aphakia, Cataract, Presbyopia
- Trial name
- NCT04177771
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD) - Pre-COVID Population, SofPort LI61AO IOL, Tecnis ZCB00 or ZTC150 IOL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- RxSight, Inc.
Presbyopia
Extended Depth of Focus Contact Lenses for Presbyopia
VTI has an FDA cleared soft contact lens product. Its optical design creates an enhanced depth of focus (EDOF), which provides clear distance, intermediate, and near vision.
- Trial name
- NCT05495971
- Testing
- NaturalVue Multifocal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc