Clinical trials: Presbyopia
Presbyopia
Post-Approval Study With the KAMRA Inlay
KAMRA inlay, to be unilaterally implanted into the cornea of a subject's non-dominant eye. The inlay is to be inserted into a stromal pocket created with a surgical femtosecond laser.
- Trial name
- NCT03173664
- Testing
- KAMRA Inlay
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Cataracts, Presbyopia
Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens
The purpose of this study is to evaluate the safety and performance of the SBL-3 intraocular lens.
- Trial name
- NCT02487160
- Testing
- SBL-3 multifocal intraocular lens, Control monofocal intraocular lens
- Where
- 13 sites in United States
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Cataract, Presbyopia
Comparison of Two Different Optical Biometric Systems
Primary objective of this study is to evaluate and compare the measurements of two different optical biometrics systems in patients who will undergo cataract surgery or presbyopia surgery using intraocular lenses (IOL-PC).
- Conditions
- Cataract, Presbyopia, Ocular Biometry, Intraocular Lens
- Trial name
- NCT05411341
- Testing
- Argos (Alcon Laboratories, Inc.), IOLMaster 500 (Carl Zeiss Meditec AG)
- Where
- Greece
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Measurement of the Elasticity of the Anterior Eye Segment
A Pilot Study to Test the Safety and Feasibility of a Brillouin Ocular Analyzer
A Brillouin ocular analyzer uses a low-power near infrared laser light to probe the viscoelastic properties of the cornea and crystalline lens in the eye.
- Trial name
- Brillouin I (NCT01775007)
- Testing
- Brillouin Ocular Analyser
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Presbyopia
Pilocarpine, Brimonidine, Oxymetazoline (PBO) Compound to Control Presbyopia Symptoms
Safety and Efficacy of Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac (PBOHB) ophthalmic compound to improve uncorrected near vision in healthy presbyopic patients one hour after instillation.
- Trial name
- PBO (NCT05006911)
- Testing
- Pilocarpine, brimonidine, oxymetazoline, hyaluronic acid, bromfenac (PBOHB) compound
- Where
- Mexico
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Optall Vision
Presbyopia
Evaluation of an Investigational Multifocal Lens
The purpose of this study is to test the performance of an investigational multifocal test soft contact lens.
- Trial name
- NCT02223754
- Testing
- lotrafilcon B, etafilcon A
- Where
- 20 sites in United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia, Refractive Error
Phase 3 Evaluation of the Safety and Efficacy of LNZ100 & LNZ101 for the Treatment of Presbyopia
Phase 3 study to evaluate the safety and effectiveness of LNZ100 \& LNZ101 for the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Error, Eye Diseases, Near Vision
- Trial name
- CLARITY 1 (NCT05656027)
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Brimonidine
- Where
- 25 sites in United States
- Volunteers
- 469 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Astigmatism, Presbyopia
Comparing Biofinity Toric Multifocal to Ultra Multifocal for Astigmatism
The objective of the study was to compare the handling and performance of Biofinity Toric Multifocal to Ultra Multifocal for Astigmatism.
- Trial name
- NCT04404725
- Testing
- comfilcon A, Samfilcon A
- Where
- 7 sites in United States, Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract, Lens Opacities
Comparison of Clinical Outcomes POD L GF vs POD F GF in Asian Eyes
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1802 (NCT03688425)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Philippines
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Presbyopia
Safety and Effectiveness of the AcuFocus Corneal Inlay ACI7000PDT in Presbyopes
The purpose of this study is to determine if the AcuFocus Corneal Inlay ACI 7000PDT will provide an effective method of for the correction of presbyopia in patients who have normal distance vision but need correction such as…
- Trial name
- NCT01352442
- Testing
- AcuFocus Corneal Inlay ACI 7000PDT
- Where
- 11 sites in Australia, Austria and 8 more
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Presbyopia
Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults
Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 2 treatment visits.
- Trial name
- VISION-2 (NCT05114486)
- Testing
- Pilocarpine Ophthalmic administered with the Optejet dispenser
- Where
- 9 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Presbyopia, Pseudophakia
Pilocarpine and Brimonidine in Patients With Monofocal Lenses
The current study aims to assess the use of pilocarpine and brimonidine to improve near visual acuity in patietns with monofocal intraocular lenses.
- Trial name
- NCT03825081
- Testing
- Brimonidine, pilocarpine
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Presbyopia
Extended Depth of Focus Contact Lenses for Presbyopia
VTI has an FDA cleared soft contact lens product. Its optical design creates an enhanced depth of focus (EDOF), which provides clear distance, intermediate, and near vision.
- Trial name
- NCT05495971
- Testing
- NaturalVue Multifocal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Presbyopia
Visual Performance of Dailies Total1 Multifocal and Acuvue Oasys Max 1-Day Multifocal in Presbyopic Lens Wearers
The purpose of this study is to measure the logMAR visual acuity when presbyopic soft lens wearers are fit with Dailies Total1 Multifocal and ACUVUE OASYS MAX 1-DAY Multifocal.
- Trial name
- GIRAFFE (NCT06369987)
- Testing
- Deleficon A (multifocal), Senofilcon A (multifocal)
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Cataract, Lens Opacities
Clinical Study to Compare Visual Performance of Two Trifocal IOLs
Prospective, randomised, controlled, single-surgeon, single-center post-market clinical follow up study to compare the clinical outcomes of two trifocal IOLs with different material
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1702 (NCT03347981)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Spain
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Presbyopia
Volumetric Visual Fields at Intermediate and Near Distances in Presbyopic Patients Using Occupational and General-Purpose Progressive Addition Lenses
This single-center, randomized, double-blind, crossover clinical trial aims to compare the volumetric visual fields provided by two occupational progressive addition lenses (OPLs) optimized for intermediate and near vision in…
- Trial name
- CIVIUS2025PAL (NCT07617090)
- Testing
- OPAL PC assesment, OPAL Office assessment, PAL assesment
- Where
- 2 sites in Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Seville
Hyperopic Presbyopia
Prospective Investigation of SUPRACOR Visual Outcomes of Presbyopic Hyperopic Patients With and Without Astigmatism
This phase IV study is an open, prospective, single-center, single-surgeon bilateral eye study to investigate the bilateral uncorrected intermediate visual acuity of presbyopic hyperopic patients, who have been treated with…
- Trial name
- NCT01628146
- Testing
- SUPRACOR LASIK treatment
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Presbyopia
A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses
The aim of this study is to validate the clinical of comfilcon A extended range high add center near (CN) multifocal lenses in existing contact lens wearers against the current comfilcon A high add multifocal lenses.
- Trial name
- NCT02719366
- Testing
- comfilcon A Extended Range test lens, comfilcon A control lens
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia, Refractive Error
Visual Performance of Prototype Contact Lens Designs
The aim of this study is to assess the visual performance of prototype soft contact lens designs compared to a commercially available contact lens
- Trial name
- NCT02193555
- Testing
- Etafilcon A, Senofilcon A
- Where
- Australia
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision
Cataract, Presbyopia
A Randomised Evaluation of Visual Function After Bilateral Implantation of Two Types of Presbyopia-correcting IOLs
Since the introduction of intraocular lenses (IOL) in the treatment of cataract, the postoperative accommodative loss of the human eye has been a trending topic.
- Trial name
- NCT03117426
- Testing
- SYMFONY IOL, AT LISA tri 839MP IOL
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center