Clinical trials: Presbyopia
Cataract
Refractive Accuracy of Argos in Conjunction With the Alcon Vision Suite Following Implantation of Presbyopia Correcting IOLs
The objective is to assess refractive accuracy of the Alcon Vision Suite (with Argos biometer) following Clareon PanOptix and AcrySof Vivity IOL implantation.
- Trial name
- NCT05901597
- Testing
- Clareon PanOptix and AcrySof Vivity IOL implantation Alcon Vision Suite and Argos biometer
- Where
- Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Valley Laser Eye Centre
Aging
Heart Aging When Near Vision Difficulty Begins
Near vision deterioration during aging results from a decrease in accomodation amplitude (AA). Myocardial regeneration is limited, and cardiac aging is an independent risk factor for cardiovascular disease.
- Trial name
- NCT04362215
- Testing
- Subjective accomodation amplitude measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Cataract, Lens Opacities
Clinical Study to Compare Visual Performance of Two Trifocal IOLs
Prospective, randomised, controlled, single-surgeon, single-center post-market clinical follow up study to compare the clinical outcomes of two trifocal IOLs with different material
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1702 (NCT03347981)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Spain
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Hyperopic Presbyopia
Prospective Investigation of SUPRACOR Visual Outcomes of Presbyopic Hyperopic Patients With and Without Astigmatism
This phase IV study is an open, prospective, single-center, single-surgeon bilateral eye study to investigate the bilateral uncorrected intermediate visual acuity of presbyopic hyperopic patients, who have been treated with…
- Trial name
- NCT01628146
- Testing
- SUPRACOR LASIK treatment
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Cataract, Presbyopia
A Clinical Evaluation of the LensGen Intraocular Lens
A multi-center, open-label, non-comparative clinical trial to assess the safety and efficacy of the LensGen IOL (Juvene IOL) for the treatment of aphakia and presbyopia after removal of the natural crystalline lens due to…
- Trial name
- Grail (NCT05364658)
- Testing
- Juvene IOL
- Where
- 2 sites in Mexico
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- LensGen, Inc.
Presbyopia, Ametropia
Clinical Trial With Artiflex Presbyopic (Artiplus)
The purpose of this clinical trial is to evaluate the effectiveness and safety of the multifocal Artiflex Presbyopic (Artiplus) intraocular lens.
- Conditions
- Presbyopia, Ametropia, Refractive Errors, Myopia
- Trial name
- NCT04632784
- Testing
- Artiflex Presbyopic (Artiplus) implantation
- Where
- 7 sites in South Korea, Spain
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ophtec BV
Presbyopia
Productivity Study of Presbyopia Improvement in Textile Workers
To establish, using a randomized, controlled design, the impact of near vision correction on the productivity of presbyopic textile workers in China, as measured by the change of monthly income.
- Trial name
- NCT04172935
- Testing
- Presbyopic Glasses/ Intervention Group
- Where
- China
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Presbyopia, Near Vision
Comparative Study and Validation of New Methodologies for Measuring Addition
The aim of this research is to collect comprehensive data on a presbyopic population that may require near vision correction, in order to identify the most useful tests to accurately determine the value of an addition.
- Conditions
- Presbyopia, Near Vision, Refraction Error
- Trial name
- NCT06963138
- Testing
- Visual Acuity, Objective refraction, Standard Subjective refraction
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Essilor International
Presbyopia, Low Vision
Ocular Biomarkers for Successful Premium Trifocal Intra-ocular Lenses Implantation
The purpose of this study is to identify ocular biomarkers that can predict the success of phacoemulsification with bilateral AT LISA try 839MP (Carl Zeiss Meditec AG) implantation to achieve satisfactory post-post-operativly…
- Trial name
- NCT05863247
- Testing
- Patient Reported Outcomes / Biometric data revision
- Where
- Portugal
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Hospital dos Lusíadas
Presbyopia
Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patients
Safety and Efficacy of Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac (PBOHB) ophthalmic compound compared to Pilocarpine and Brimonidine to improve uncorrected near vision in healthy presbyopic patients one…
- Trial name
- PBOHB (NCT05001243)
- Testing
- Compound Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac, Pilocarpine Hydrochloride, Brimonidine Tartrate
- Where
- Mexico
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Optall Vision
Visual Acuity
Evaluation of A Marketed Silicone Hydrogel Spherical Lens Used for Monovision Correction of Presbyopia
This is a single-masked, dispensing clinical trial. A total of approximately 48 myopic and 32 hyperopic eligible subjects will be targeted to complete the study.
- Trial name
- NCT04073186
- Testing
- ACUVUE® OASYS with Transitions™
- Where
- 5 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract, Presbyopia Correction
The Purpose is to Evaluate Visual Acuity for Distance, Intermediate and Near and Additionally Contrast Sensitivity at 25% and 10% of Illumination After Implantation of Trifocal IOL, Extended Range of Vision IOL, Bifocal IOL With Low Addition and Monofocal IOL
The objective of this study was to evaluate the effect of intraocular lens (IOL) selection on visual acuity and refractive outcomes, to assess the impact of IOL type on postoperative contrast sensitivity, and to investigate…
- Conditions
- Cataract, Presbyopia Correction, Visual Acuity
- Trial name
- IOL (NCT07008768)
- Testing
- Cataract surgery and refractive lens exchange surgery, TRIFOCAL IOL, EROV IOL
- Where
- Croatia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University Eye Hospital Svjetlost
Presbyopia
Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults
Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 2 treatment visits.
- Trial name
- VISION-2 (NCT05114486)
- Testing
- Pilocarpine Ophthalmic administered with the Optejet dispenser
- Where
- 9 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Cataract, Presbyopia
Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas
The objective of this study is to evaluate the clinical outcomes of the IC-8 IOL implanted in patients with complex corneas after crystalline lens removal.
- Conditions
- Cataract, Presbyopia, Irregular Astigmatism
- Trial name
- NCT05574270
- Testing
- IC-8 Intraocular Lens (IOL)
- Where
- 2 sites in Philippines, Singapore
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Presbyopia, Refractive Errors
Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia
To evaluate the safety and effectiveness of Aceclidine/Brimonidine (LNZ101) compared with Aceclidine (LNZ100) and vehicle in the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05294328
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle Proprietary Ophthalmic Solution
- Where
- 5 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Presbyopia
Mix and Match Study of Two Multifocal Intraocular Lens With Different Add Power
To assess postsurgical visual acuity (distant, intermediate, near), refractive errors, contrast sensitivity, visual function and patient satisfaction after implantation of multifocal IOLs of different add power contralaterally.
- Trial name
- NCT02556944
- Testing
- Phacoemulsification with multifocal intraocular lens
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- tae-young chung
Myopia, Hyperopia
Development of a Validated Chart for Intermediate Vision Assessment
Development of a validated computer-based instrument (software program) for the assessment of intermediate visual acuity.
- Conditions
- Myopia, Hyperopia, Presbyopia, Astigmatism
- Trial name
- NCT02279446
- Testing
- Intermediate Visual acuity (IVA) assessment
- Where
- Greece
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Ametropia, Myopia
Apioc Contact Lens Feasibility
This clinical trial will document the feasibility of the Apioc lens design by assessing which lens shape parameters yield successful on-eye-fit and movement of the Apioc contact lens design and evaluate the subjectively-reported…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03688672
- Testing
- Apioc Contact Lens Design
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Presbyopia
Evaluation of Soft Multifocal Lenses in Presbyopic Previous Contact Lens Wearers
To explore the wear experience in Dailies TOTAL1 Multifocal contact lenses in presbyopic adults who have previously dropped out of contact lens wear.
- Trial name
- NCT06053463
- Testing
- Daily disposable multifocal soft contact lens
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jennifer Fogt
Cataract, Lens Opacities
Implantation of a Trifocal Hydrophobic IOL in Patients That Underwent Refractive Surgery
Controlled, open label, prospective Post Market Clinical Follow-Up, single-center clinical study to investigate visual performance after implantation of a trifocal IOL (PhysIOL Pod L GF) in patients that underwent refractive…
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT04054427
- Testing
- IOL implantation experimental
- Volunteers
- healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.