Clinical trials: Prescription
Pain
Oxycodone User Registry (OUR)
The purpose of this study is to describe clinical and demographic characteristics of patients receiving prescription medications containing oxycodone immediate release (OXYRX), to characterize patient and prescriber perceptions…
- Trial name
- NCT00978328
- Testing
- oxycodone immediate release (OXYRX)
- Volunteers
- 827 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Acute Pain
Open Label Placebo to Reduce Prescription Opioid Use
The goal of the proposed study is to examine the efficacy of using an honest placebo to relieve pain for patients with an acute pain condition.
- Trial name
- NCT05014230
- Testing
- Opioid medication as part of standard care
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Brown University
Gram-negative Bacteremia, Intensive Care Patients
Impact of Real-time MIC (Minimum Inhibitory Concentration) Reporting (<6 Hours) on β-lactam Prescription in Cases of Gram-negative Bacilli Bacteremia in ICU Patients in Real-life Settings
Evaluate the impact of rapid, real-time (4 to 6 h) MIC reporting compared with the standard method (=diffusion antibiotic susceptibility testing) (18 to 24 h) on β-lactam prescribing in terms of the choice of molecule by the…
- Trial name
- CMIBActRéa (NCT07202377)
- Testing
- SPECIFIC REVEAL® Rapid AST system, antibiotic susceptibility testing on agar medium
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diet, Healthy, Overweight and Obesity
Food Prescriptions to Promote Affordable Diets
This is an Randomized controlled trial (RCT) to assess the impact of meal planning and affordable grocery delivery on weight loss, dietary quality and health on members of multigenerational Latino households.
- Trial name
- FoodRx (NCT05309395)
- Testing
- FoodRx
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Alcohol Use, Cannabis Use
MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education
The MATAspire intervention is a web-app designed to promote substance misuse prevention education and bolster protective coping skills whereby students complete six weekly interactive modules using a smart device or computer.
- Conditions
- Alcohol Use, Cannabis Use, Nicotine Use, Illicit Drug Use
- Trial name
- MATAspire (NCT06553196)
- Testing
- MATAspire Web-app
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- California State University, Northridge
Food Insecurity
FreshStart for Health Study
The goal of this study is to test whether a produce prescription program (FS4H) influences health behaviors and food security. FS4H engages a total of 4 cohorts to receive fresh local produce and nutrition lessons.
- Trial name
- FS4H (NCT07815756)
- Testing
- Produce prescription, Nutrition education
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cornell University
Intestinal Insufficiency, Short Bowel Syndrome
Prescription Pattern of Adjuvant Drugs and Vitamins in Patients Undergoing Long-term Home Nutritional Support for Intestinal Insufficiency
Intestinal insufficiency due to short bowel syndrome is a chronic, disabling condition with significant morbidity and mortality.Standard care includes home parenteral/enteral nutrition as well as intestinal transplantation…
- Trial name
- NCT01696656
- Testing
- Drug prescription pattern
- Where
- Brazil
- Volunteers
- 37 people
- Sponsor
- University of Sao Paulo
Opioid Overdose, Substance Use Disorders
Quantitative Xylazine Measurement in ED
Quantitative Xylazine Measurement Among Non-Fatal Opioid Overdose (OD) Patients in the Emergency Department (ED)
- Trial name
- NCT06949605
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Opioid Related Disorders
Computer-based Prescription Opioid Abuse Prevention for Adolescents
The investigators are developing an interactive, web-based program for youth ages 12-17 focused on the prevention of prescription opioid abuse because to the investigators knowledge, no science-based, interactive program focused…
- Trial name
- NCT02737696
- Testing
- Web-based prescription opioid prevention for adolescents, JustThinkTwice.gov website (DEA)
- Where
- United States
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
COPD
Intervention to Reduce Misused Inhaler and Insufficient Peak Inspiratory Flow in Hospitalized COPD Patients
The drug treatment of chronic obstructive pulmonary disease (COPD) is mainly based on inhaled therapy. This route of administration is limited by inhaler handling errors, insufficient inspiratory flow or inappropriate inhalers.
- Trial name
- MIPIF (NCT05207631)
- Testing
- Systematic and standardised assessment of inhalers and implementation of a prescribing guide
- Where
- Switzerland
- Volunteers
- 101 people
- Sponsor
- Hôpital Fribourgeois
Ankle Foot Orthosis (AFO), Stroke Patients
AFO Prescription to Optimize Post-Stroke Function
The overall goal of this study is to attain the highest possible health-related quality of life for individuals with lower-limb impairment through a clinical trial examining three different modern carbon fiber ankle-foot orthosis…
- Conditions
- Ankle Foot Orthosis (AFO), Stroke Patients, Post-Stroke Hemiparesis
- Trial name
- NCT06692686
- Testing
- Pre-fabricated (PF) ankle-foot orthosis (AFO), Carbon-strut (CS) ankle-foot orthosis (AFO), Multifunctional articulating (MA) ankle-foot orthosis (AFO)
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Texas at Austin
Drug Overdose
A Usability Assessment of Naloxone by Community Members
This will be a usability trial to assess administration of naloxone via intramuscular, atomized intranasal, and nasal spray routes by nonmedical community members.
- Trial name
- NCT03309449
- Testing
- Syringe and needle, Intranasal mucosal atomization device, Nasal spray
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Acute Kidney Injury, Kidney Replacement
Proactive Prescription-based Fluid Management vs Usual Care in Critically Ill Patients on Kidney Replacement Therapy
A pilot randomized clinical trial comparing a protocol-based fluid management strategy to usual care in critically ill patients receiving kidney replacement therapy.
- Conditions
- Acute Kidney Injury, Kidney Replacement, Critical Illness
- Trial name
- Probe-Fluid (NCT05473143)
- Testing
- Protocol-based fluid management, Usual care
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Spondylitis, Ankylosing, Mobile Phone Use
Exploratory Investigation of the Acceptance and Utility of 14-day Trial Periods and Application-related Outcome Measurement (AbEM) Within the Routine Prescription of the DiGA Axia.
This prospective, multicenter, controlled real-world quality management study explores the acceptance and utility of two measures discussed in the context of the German Digital Act (DigiG) for the digital health application…
- Trial name
- RAEMD (NCT07561255)
- Testing
- Test-phase with immediate access, Standard procedure
- Where
- 7 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Wuerzburg University Hospital
Compliance, Patient, Treatment Adherence
Treatment Adherence With Twin-Blocks for Correction of Class II Malocclusion
To compare the effect of two control intervals (once every 4th week or once every 6th week) on the wear time of a Twin Block removable appliance.
- Trial name
- NCT05155774
- Testing
- Twin block
- Where
- Sweden
- Volunteers
- 73 people
- Sponsor
- Region Jönköping County
Stroke, Embolism
Non-interventional Local Study on Prescription Behavior of Anticoagulation Therapy in Secondary Stroke Prevention in Atrial Fibrillation Patients
This is local prospective multicenter observational non-interventional local study. Primary study objective is investigate and describe prescription pattern of neurologists in secondary stroke or non-CNS (non-Central Nervous…
- Trial name
- NEURO-XAR (NCT01925755)
- Testing
- Rivaroxaban ( Xarelto, BAY59-7939)
- Where
- Russia
- Volunteers
- 209 people
- Sponsor
- Bayer
Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use
TAPS-ESP: Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use Electronic Spanish Platform
This Phase 1 STTR project will develop a technology platform for delivering the TAPS Tool to a Spanish-speaking, health disparity population in a community health center.
- Trial name
- TASP-ESP (NCT03879785)
- Testing
- Screening
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Rheumatoid Arthritis
IL-6 as a Biomarker for Personalized Treatment of PR
Several studies have shown the relevance of the IL6 level before treatment or after 6 months, as a predictive biomarker for the persistence of remission.
- Trial name
- REMISIX (NCT04779983)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Schizophrenia, Schizoaffective Disorder
Magnesium Variations and Cardiometabolic Risk in Patients With Antipsychotic Drugs
Background: Antipsychotics can induce metabolic disorders such as obesity, hyperglycemia, dyslipidemia or metabolic syndrome. It has been observed that treatment with antipsychotic could be accompanied by a decrease in the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT02986490
- Testing
- Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Opioid Use, Acute Pain
Appropriate Opioid Quantities for Acute Pain - Pharmacist Study
Prescription opioids contribute to opioid related deaths, overdose and addiction. Unused prescribed opioids are not routinely being stored or disposed of appropriately and their availability is associated with harms.
- Trial name
- NCT04484610
- Testing
- Pharmacist Practice Change to Dispense Appropriate Opioid Quantities for Acute Pain
- Where
- Canada
- Volunteers
- 205 people
- Sponsor
- Centre for Addiction and Mental Health
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