Clinical trials: Prescription
Migraine, Episodic Migraine
Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C)
Randomized study of two digital therapeutics for the prevention of episodic migraine in patients currently receiving Calcitonin Gene-Related Peptide (CGRP) Inhibitor Therapy
- Conditions
- Migraine, Episodic Migraine, Headache, Headache, Migraine
- Trial name
- NCT06004388
- Testing
- Click Digital Therapeutic
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Click Therapeutics, Inc.
Amikacin Treatment
Prescription Strategies of Amikacin in Intensive Care Patients on Renal Replacement Therapy: an Observational Prospective Multicenter Study
Amikacin is the aminoglycoside of choice for treatment of severe infections in intensive care. An achievement of its objectives in pharmacokinetics and pharmacodynamics is difficult in intensive care patients because of…
- Trial name
- AMIDIAL-ICU (NCT04322019)
- Testing
- Data record
- Where
- France
- Volunteers
- 112 people
- Sponsor
- CHU de Reims
Osteoarthritis, Gastroesophageal Reflux Disease
Prescription Methods Assessment Project (PMAP)
The purpose of this study is to evaluate whether a novel prescription method (N-of-1 intervention)can be successfully integrated into primary care practices and to examine the effects of this prescription method on selected…
- Trial name
- NCT00393653
- Testing
- N-of-1 prescription method
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- American Academy of Family Physicians
Cognitive Change, Health Behavior
A Multidomain Approach to Preventing Dementia in African Americans: Cognitive Prescriptions
The goal of this R21 study is to explore the feasibility and preliminary efficacy of individualized cognitive prescriptions (CogRxs) in improving engagement in healthy behaviors and other outcomes in middle-aged AAs and to gain…
- Conditions
- Cognitive Change, Health Behavior, Health Literacy
- Trial name
- NCT03864536
- Testing
- Cognitive Prescriptions
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Neuropathy, Diabetic, Neuropathy;Peripheral
Clinical Efficacy and Human Factors Validation Testing of the Erchonia EVRL for Providing Temporary Relief of Diabetic Peripheral Neuropathy Foot Pain
The purpose of this clinical study is to determine the effectiveness of the Erchonia® EVRL™, manufactured by Erchonia Corporation (the Company), in providing prescription home use application for temporary relief of diabetic…
- Conditions
- Neuropathy, Diabetic, Neuropathy;Peripheral, Neuropathy, Painful
- Trial name
- NCT05291975
- Testing
- Erchonia® EVRL™
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- Erchonia Corporation
Mental Disorder, Physical Activity
Physical Activity Recommendation Behaviour in German Psychologists
The purpose of this study is to examine the physical activity recommendation behaviour, beliefs, barriers and exercise participation in German psychologists working with patients with mental disorders.
- Trial name
- NCT04149795
- Testing
- Online questionnaire
- Where
- Germany
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Suicide, Overdose Accidental
Pilot of Training on 988 and Narcan
This pilot study evaluates the acceptability, appropriateness, and feasibility of a new crisis response training called Crisis Ready.
- Conditions
- Suicide, Overdose Accidental, Overdose Antidote, Crisis Response Plan
- Trial name
- NCT07072819
- Testing
- Crisis Ready Training
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- RAND
Surgery, Opioid Use
Increasing Implementation of Post-Operative Opioid Prescribing Guidelines
The objective of this research study is to evaluate the effect of a quality improvement initiative carried out by a health system opioid stewardship task force aiming to increase clinician post-operative prescribing adherence…
- Conditions
- Surgery, Opioid Use, Opioid Misuse, Prescription Opioid Misuse
- Trial name
- NCT05358522
- Testing
- Opioid Prescribing Report Cards
- Where
- United States
- Volunteers
- 26,562 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Respiratory Tract Infections
Long Term Effect of General Practitioner Education on Antibiotic Prescribing
Respiratory tract infections are the most common indication for antibiotic prescribing in primary care. Several studies have shown a strong relationship between antibiotic use and bacterial resistance.
- Trial name
- PAAIR2 (NCT01107223)
- Testing
- Experimental: Training to antibiotic prescription, No education on antibiotic prescription rules.
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Henri Mondor University Hospital
Physical Inactivity
Understanding Motivation Towards Exercise to Enhance Physical Activity on Prescription Adherence - Feasibility Study
The goal of this clinical trial is to explore feasibility and evaluate methods to investigate changes in physical activity, function and psychometrics in relation to an exercise intervention in physically inactive middle-aged men…
- Trial name
- UMEPA-F (NCT05691803)
- Testing
- Exercise intervention
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Umeå University
Obesity, Physical Activity
Bridging Resources Improve the Development of Guideline-based Exercise
The purpose of this pilot study is to more effectively deliver the current standard of care for obesity and physical activity based on current guidelines.
- Trial name
- BRIDGE (NCT03678974)
- Testing
- Exercise Prescription
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Infection
Impact of Clinical Guidance & Point-of-care CRP in Children: the ARON Project
Impact of clinical guidance \& point-of-care CRP test in children: the ARON project Trial Design: multicentre, cluster-randomized, parallel group pragmatic trial Trial Participants and setting: Children aged 6 months to 12 years…
- Trial name
- ARON (NCT04470518)
- Testing
- diagnostic algorithm
- Where
- Belgium
- Volunteers
- 6,750 people
- Sponsor
- KU Leuven
Medication Abuse, Harm Reduction
Evaluation of Clinical Decision Support in Opioid Tapering
The 2022 Center for Disease Control and Prevention (CDC) clinical practice guideline for prescribing opioids for pain recommends that when tapering a patient's opioid dose, doses should be decreased at a slow rate to reduce the…
- Conditions
- Medication Abuse, Harm Reduction, Opioid Use Disorder, Opioid Prescribing
- Trial name
- NCT06527079
- Testing
- Observational study without a prospective intervention
- Volunteers
- 200,000 people
- Sponsor
- University of Colorado, Denver
Irritable Bowel Syndrome, Traditional Chinese Medicine
Trial of Chinese Prescription Shugan Decoction on Irritable Bowel Syndrome（Diarrhea Type）
The purpose of this study is to evaluate the efficacy and safety of the Chinese prescription Shugan decoction on irritable bowel syndrome（diarrhea type）.
- Trial name
- NCT00948870
- Testing
- Shugan decoction
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Opioid Use Disorder
Feasibility Study of Novel Prescription Digital Therapeutic Supporting Unobserved Buprenorphine Initiation & Adherence
The purpose of this study is to assess feasibility of an at-home digital therapy designed to support buprenorphine initiation and adherence.
- Trial name
- NCT05412966
- Testing
- PEAR-002B, reSET-O
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Pear Therapeutics, Inc.
Schizophrenia
Exploratory Study of a Digital Therapeutics in People With Schizophrenia
CT-155 is a novel prescription digital therapeutic (PDT) being developed by Click Therapeutics, Inc. (Click) and Boehringer Ingelheim (BI) using an interactive, software-based intervention to treat schizophrenia
- Trial name
- NCT05438160
- Testing
- Clinical Learning Study smartphone app (i.e., the study app)
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- Click Therapeutics, Inc.
Opioid-use Disorder, Overdose
Rapid Initiation of Drug Treatment Engagement
The proposed research will evaluate the ability of a mobile, rapid induction procedure to engage individuals in ongoing medication assisted treatment.
- Trial name
- RIDE (NCT03908437)
- Testing
- buprenorphine/naloxone
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Pennsylvania
Neurodermatitis
Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (PRIME2)
Primary Objective: To demonstrate the efficacy of dupilumab on itch response in participants with prurigo nodularis (PN), inadequately controlled on topical prescription therapy or when those therapies are not advisable.
- Trial name
- NCT04202679
- Testing
- Dupilumab SAR231893, Moisturizers, Low to medium potent topical corticosteroids
- Where
- 57 sites in United States, Canada and 9 more
- Volunteers
- 160 people
- Sponsor
- Sanofi
Schizophrenia, Bipolar Disorders
The Purpose of the Study is to Gain an In-depth Picture of the Patient Management and Prescription Behaviours
'Real life' retrospective patient cases (10) to provide an objective and robust analytical report of patient management and prescriptions behaviours for Schizophrenia, Bipolar disorders and Major depressive disorders.
- Conditions
- Schizophrenia, Bipolar Disorders, Major Depressive Disorders
- Trial name
- NCT01377896
- Volunteers
- 221 people
- Sponsor
- AstraZeneca
Sedentary Lifestyle, Cardiovascular Diseases
Physical Exercise Prescription With PEdometeR in General Practice for Patients With Cardiovascular Risk Factors - PEPPER
This study evaluates the efficacy, in terms of energy expenditure, physical activity level, quality of life, blood pressure, waist circumference and weight, of a general practice based intervention involving a personalised…
- Conditions
- Sedentary Lifestyle, Cardiovascular Diseases, Hypertension, Hypercholesterolemia
- Trial name
- PEPPER (NCT02317003)
- Testing
- Intervention PPIL, Control OR
- Where
- France
- Volunteers
- 126 people
- Sponsor
- University Hospital, Angers
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