Clinical trials: Prescription
Knowledge, Attitudes, Practice
Reducing Prescription Opioid Misuse: ROPEs Pilot Trial
This is a randomized controlled pilot trial to establish methodological feasibility and determine whether a web-based, continuing dental education intervention regarding opioid prescribing risk mitigation strategies - consistent…
- Trial name
- NCT03691948
- Testing
- Responsible Opioid Prescriber Education (ROPES), Active Comparator Control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Economics, Fraud
The Effect of Informative Letters on the Prescription and Receipt of Schedule II Controlled Substances
Fraud and waste is estimated to cost the American health care system nearly $200 billion each year, and the public Medicare and Medicaid programs about $60 billion each year.
- Conditions
- Economics, Fraud, Delivery of Health Care, Health Expenditures
- Trial name
- NCT02345434
- Testing
- Informative letter
- Volunteers
- 1,525 people, healthy volunteers welcome
- Sponsor
- Abdul Latif Jameel Poverty Action Lab
Peptic Ulcer Disease
Inventory of Inappropriate Prescriptions of Proton Pump Inhibitors (PPIs) in People Over 75 Years of Age
This study would have as a starting point the results of a request carried out by the Medical Service Grand Est of the Health Insurance aiming to evaluate the number of boxes of PPI reimbursed in town pharmacy, in patients over…
- Trial name
- Etaliepre-IPP (NCT05618249)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Overdose
Overdose Prevention Centers and Behavioral Health
The aims of this study are: (Aim 1) Identify sources of heterogeneous impacts of opioid prevention center (OPC) use on non-fatal and fatal overdose risk among individuals with histories of polysubstance use (PSU); (Aim 2)…
- Trial name
- NCT06236087
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- NYU Langone Health
Vaping, E Cig Use
A Hybrid Program to Prevent Substance Use Risk Among Upper Elementary School Students Using a Positive Youth Development Approach
The goal of this randomized controlled trial is to evaluate a psychosocial school-based hybrid intervention which includes traditional classroom sessions and online e-learning modules to reduce risk of vaping and prescription…
- Conditions
- Vaping, E Cig Use, Prescription Drug Misuse
- Trial name
- NCT07162155
- Testing
- School-based Hybrid Intervention to Prevent Vaping and Prescription Drug Misuse
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Christopher Williams
Opioid Abuse
Naloxone Treatment in Skåne County - Effect on Drug-related Mortality and Overdose-related Complications
Death in overdose is the single most common cause of death in people using heroin. In Sweden, the number of drug-related overdose deaths has increased gradually since the early 1990s.
- Trial name
- NCT03570099
- Testing
- Naloxone Nasal Spray, Historical control cohort
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Paediatric Surgery, Analgesics Prescriptions
Setting up a Website in Paediatric Surgery at the Rouen University Hospital for Parents and Children to Better Understand the Postoperative Prescription of Painkillers.
Although outpatient surgery is increasing in France, particularly in paediatrics, compliance with analgesics prescriptions and pain management on return home remain poorly controlled parameters, although they are essential for…
- Trial name
- DOLIPAR (NCT04564248)
- Testing
- Website access
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Rouen
Primary Health Care for Children
Impact of a Real-time Mentoring Tool on Antibiotic Prescription (medAL-mentor)
The goal of this ancillary study, part of the DYNAMIC project, is to reduce antibiotic prescription and improve the quality of care for children in primary care in Tanzania using a near real-time mentoring tool (called…
- Trial name
- medAL-mentor (NCT05901155)
- Testing
- MedAL-mentor
- Where
- 40 sites in Tanzania
- Volunteers
- 37,000 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Fever
The Impact of C-reactive Protein Testing
PRIMARY OBJECTIVE To assess the impact of C-reactive protein (CRP) Point-of-care (POC) testing on health care worker prescribing behaviour in patients presenting to primary healthcare centres with an acute fever or recent history…
- Trial name
- NCT02758821
- Testing
- No CRP will be measured onsite, CRP cut-off of 20mg/L., CRP cut-off of 40mg/L.
- Where
- Thailand
- Volunteers
- 2,410 people
- Sponsor
- University of Oxford
Opioid Overdose
Project OOPEN: Opioid Overdose Prevention, Education and Intervention
This prospective, randomized emergency department trial will study the effectiveness of an intervention that combines opioid overdose prevention, education and intervention that includes take home naloxone with brief behavioral…
- Trial name
- OOPEN (NCT01788306)
- Testing
- OOPEN+BBCC
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- University of Washington
Hypertension, Hyperglycemia
Prospective Exploratory Study on the Comprehensive Application Effectiveness of Exercise Prescription Decision Support Tools in the Management of Patients With "Four Highs" (Hypertension, Hyperglycemia, Hyperlipidemia, Hyperuricemia)
This study conducted a six-month exploratory clinical trial to evaluate the impact of an exercise prescription mini-program, based on the "Exercise Guidelines for the 'Four Highs'", on the physical activity levels and related…
- Conditions
- Hypertension, Hyperglycemia, Hyperlipidemia, Hyperuricemia
- Trial name
- NCT07400549
- Testing
- Enhanced Mini-Program Intervention, Enhanced Control
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Food Insecurity
Comparison of Produce Prescription Benefit Dosage
The goal of this study is to determine the relationship between produce prescription program 'dose' on benefit redemption, food insecurity, and fruit and vegetable consumption.
- Trial name
- NCT05978843
- Testing
- Monetary benefit to purchase fruits and vegetables
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Recreational Drug Use, Prescription Drug Abuse (Not Dependent)
A Study of the Abuse Potential of Lasmiditan in Participants Who Are Recreational Drug Users
The purpose of this study is to assess the abuse potential of study drug lasmiditan. Lasmiditan will be compared to a marketed benzodiazepine, alprazolam (positive control), as well as to placebo (dummy substance that looks like…
- Trial name
- NCT03286218
- Testing
- Lasmiditan, Alprazolam
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Prescription Pattern
Academic Detailing About Proton Pump Inhibitors
General practices in the Capital Region of Denmark are offered a short educational visit and are randomized to either proton pump inhibitor (intervention) or another topic (control).
- Trial name
- BRIEF-PI (NCT05443789)
- Testing
- Proton pump inhibitor education, Other education
- Where
- Denmark
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Jón Þór Trærup Andersen
Decision Making, Shared
DECIdE, Shared DECIsion in hEalth : the Real-life Impact Study
The aim of the DECIdE study is to evaluate the effect of a decision aid (the DECIdE tool) for shared decision making concerning optional prescription drugs on the level of uncertainty-certainty or comfort-inconfort (= decisional…
- Trial name
- DECIdE (NCT06052917)
- Testing
- DECIdE
- Where
- 4 sites in France
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Respiratory Tract Infection
Antibiotics in Patients With Acute Respiratory Tract Infection With Procalcitonin as Parameter
Antibiotics in patients with acute respiratory tract infections in primary care in consideration of procalcitonin as additive parameter.
- Trial name
- NCT00688610
- Testing
- laboratory value procalcitonin
- Where
- Germany
- Volunteers
- 571 people
- Sponsor
- Hannover Medical School
Physical Activity, Sedentary Lifestyle
Activity Prescription in Clinical Practice
Most adults do not achieve the US aerobic physical activity (PA) guidelines (≥150 minutes/week of at least moderate intensity PA).
- Trial name
- NCT03695016
- Testing
- ActiveGOALs
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Pittsburgh
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Chronic Disease
Potentially Inappropriate Prescription Associated to Multimorbidity
A prospective multicenter cohort study in 5 hospitals in Spain will be initiated in 2016. Objectives: 1. To estimate and describe patterns of multimorbidity and polypharmacy in patients over 64 admitted for a chronic disease…
- Trial name
- PIMyC (NCT02830425)
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 740 people
- Sponsor
- Corporacion Parc Tauli
Chronic Atrophic Gastritis
Treatment of Atrophic Gastritis After HP Eradication With Modified Liujunzi Decoction Based on Syndrome Differentiation
This is an observational cohort study of clinical efficacy study.The purpose of this topic is to evaluate the efficacy and safety of Modified Liujunzi Decoction based on syndrome differentiation in patients with chronic atrophic…
- Trial name
- NCT05388890
- Testing
- MLD, WFC
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Peking University First Hospital
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