Clinical trials: Prescription
Inappropriate Dose of Drug Administered, Health Behavior
A Trial to De-prescribe Inappropriate Medications in the Community Dwelling Elderly
The objective of this trial is to test the beneficial effect of a pharmacist-initiated knowledge transfer intervention to both patients and prescribers on the discontinuation of inappropriate prescriptions, compared to usual…
- Trial name
- D-PRESCRIBE (NCT02053194)
- Testing
- Pharmacist-led educational intervention
- Volunteers
- 600 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Chronic Obstructive Pulmonary Disease
Using Clinical Prediction Models to Improve Treatment for Patients With Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease of the lungs that affects more than 2.5 million Canadians. Patients with COPD experience episodes of lung attacks (or exacerbations).
- Trial name
- NCT05309356
- Testing
- ACCEPT Decision Intervention, Comparator
- Where
- 2 sites in Canada
- Volunteers
- 1,130 people
- Sponsor
- University of British Columbia
Medication Errors
Evaluation of an Outpatient Modified Prescription Form
The purpose of this study is to determine if a modified paper prescribing form decreases prescribing errors compared to a traditional or standard paper prescribing form.
- Trial name
- NCT00256594
- Testing
- prescription form
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Obesity, Morbid, Drug Use
Evaluation of the Implementation of Drug Prescription Recommendations Using Clinical Decision Support in Patients With Severe Obesity: Retrospective Study
No drug prescription guidelines for severe obesity (BMI>35 kg/m2) are available, leading to non-standardized and / or potentially inappropriate drug management.
- Trial name
- RECOB-MED (NCT06517303)
- Where
- 2 sites in France
- Volunteers
- 1,050 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Opioids; Harmful Use
Piloting a Naloxone Intervention in Philadelphia
The escalating opioid overdose epidemic is one of the most serious public health problems confronting the U.S. Death due to drug overdose is a significant and rising cause of mortality and morbidity in Philadelphia.
- Trial name
- NCT03305497
- Testing
- Mobile Phone Application
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Drexel University
Drug Advice by Phone
Assessment of Drug Prescription by Phone
Prescription of medicines by telephone in French medical call Centres is a part of the general practitioners activity. This study aimed to described drug prescription by phone (MTP) performed in four medical call centers.
- Trial name
- TELEPRES (NCT02889120)
- Volunteers
- 1,263 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Drug Overdose
Pharmacodynamics and Arteriovenous Differences of Naloxone in Healthy Participants Exposed to an Opioid
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. To save lives, immediate treatment with a μ-opioid antidote such as naloxone is required.
- Trial name
- OPI-15-001 (NCT02405988)
- Testing
- Intravenous naloxone, Remifentanil
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Adverse Events
Strategies for Improving Proton Pump Inhibitors (PPIs) Prescription Associated to Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Background Despite the low prevalence of serious complications associated with non-steroidal anti-inflammatory drugs (NSAIDs) use, there is a widespread use of gastroprotective proton pump inhibitors (PPIs) in order to prevent…
- Trial name
- NCT01128127
- Testing
- Group education, audit-feedback and computer support, Audit-feedback and computer support, Control
- Where
- Spain
- Sponsor
- Servicio Canario de Salud
Type 2 Diabetes
Cardiometabolic Impact of a Produce Prescription Program in Patients With Type 2 Diabetes and Food Insecurity
This study is testing whether providing monthly vouchers to buy fruits and vegetables can help improve blood sugar control in adults with type 2 diabetes.
- Trial name
- GARDEN-CARDIO (NCT07674979)
- Testing
- Produce Gift Card and Dietary Education, Usual Care
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- West Virginia University
Cancer Patients, Cancer-related Pain
A Consensus on Opioid Prescription for Oncologic Patients in Latin America - A DELPHI Study.
As seen worldwide, cancer incidence is increasing in Latin America achieving an amount of 1.3 million new cases annually.1 In addition, it is expected that up to 70% of patients with cancer will experience pain2, one of the most…
- Trial name
- NCT04844788
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Psychiatric Disorder
Prescription of Valproate and Derivatives in Women of Childbearing Age: Qualitative Study
The prescription of valproate in women of childbearing age has decreased by 82% in France, for mood disorders. Exposure to valproate during pregnancy 60%.
- Trial name
- VALPRO (NCT06499779)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Opioid Dependence
Buprenorphine Treatment for Opioid Dependence
Buprenorphine/naloxone (BUP/NLX) treatment is effective for the treatment of prescription opioid dependence, previous studies have not determined the optimum dose of BUP/NLX for this patient population.
- Trial name
- NCT02187198
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Yale University
Prescription Practices of Family Physicians in NL
Randomized Controlled Study to Incentivize Doctors for Appropriate Use of Medical Care in NL
Choosing Wisely Canada is a campaign for promoting appropriate use of medical services to reduce unnecessary prescribing and unnecessary diagnostic tests.
- Trial name
- NCT03488121
- Testing
- Poster, Thank-you Letter
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
PreDiabetes
Social Prescription and Lifestyles Modification to Reduce Glycemia in People With Prediabetes (PREDIBAL)
This study aims to evaluate the effectiveness and cost-utility of an intervention based on the social prescription of health assets to modify lifestyles and reduce blood glucose values in prediabetic patients in primary care…
- Trial name
- PREDIBAL (NCT04328363)
- Testing
- Intervention
- Volunteers
- 232 people
- Sponsor
- University of the Balearic Islands
Economics, Fraud
The Effect of Informative Letters on the Prescription and Receipt of Seroquel
Abusive prescribing exposes patients to unnecessary health risks and results in wasteful public expenditures. This study will evaluate an innovative approach to fighting abusive prescription: sending letters to suspected…
- Conditions
- Economics, Fraud, Delivery of Health Care, Health Expenditures
- Trial name
- NCT02467933
- Testing
- Initial Informative letter, Followup Informative Letter
- Volunteers
- 5,055 people, healthy volunteers welcome
- Sponsor
- Abdul Latif Jameel Poverty Action Lab
Infections
Improving Post-discharge Antimicrobial Use
One in five hospitalized patients is prescribed an antimicrobial at the time of discharge, and a large proportion of these post-discharge antimicrobials are unnecessary.
- Trial name
- NCT05471726
- Testing
- Prospective audit-and-feedback
- Where
- 5 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Medication Adherence
Improvement of Intentional and Unintentional Non-adherence in the Elderly
The purpose is to study if different factors influence medicine adherence in elderly people. In this study number of generic substitution and use of non-prescription drugs, herbal medicine and dietary supplement is in focus.
- Trial name
- NCT01512238
- Testing
- Pharmaceutical care
- Volunteers
- 630 people
- Sponsor
- University of Aarhus
Depression, Anxiety
Evaluation of the Relevance of Pharmacogenetics in the Prescription Off Antidepressants in a Military Population
The treatment of depression, anxiety disorders and post-traumatic stress disorder (PTSD) is a main public health problem due to the frequency of these pathologies and the very partial effectiveness of the existent therapies.
- Conditions
- Depression, Anxiety, Ptsd
- Trial name
- PSYGEN (NCT04987047)
- Testing
- Blood collection, Questionnaires, Cognitive test battery (optional)
- Where
- 4 sites in France
- Volunteers
- 250 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Feasibility Studies, Physical Activity
AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study
The purpose of this research is to investigate the feasibility, acceptability, appropriateness, and preliminary efficacy of a wearable and artificial intelligence-driven mobile application-based exercise prescription grounded in…
- Conditions
- Feasibility Studies, Physical Activity, Mental Health (Depression), Anxiety
- Trial name
- NCT07768670
- Testing
- Fitness app powered by AI and wearable device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Body Weight Changes
Development of a Nutrigenetic Test for Personalized Prescription of Body Weight Loss Diets (Obekit)
This study evaluates the relationship between several genetic variants and the response to a hypocaloric diet, in order to design a genetic test which permits prescribe the more personalized diet for each individual according to…
- Trial name
- Obekit (NCT02737267)
- Testing
- Moderately high protein diet, Low fat diet
- Where
- Spain
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
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