Clinical trials: Prescription
Depression, Anxiety
More Individualized Care: Assessment and Recovery Through Engagement
The MI-CARE trial tests 12 months of telephone-based nurse care management for patients with depressive symptoms who take or have taken opioids at some time.
- Conditions
- Depression, Anxiety, Opioid-Related Disorders, Pain, Chronic
- Trial name
- MI-CARE (NCT05122676)
- Testing
- More Individualized Care: Assessment and Recovery through Engagement (MI-CARE)
- Where
- 2 sites in United States
- Volunteers
- 805 people
- Sponsor
- Kaiser Permanente
Lower Limb Trauma, Venous Thromboembolism
Thromboembolic Risk Stratification by TRiP(Cast) Score to Guide Physicians in Preventive Treatment Prescriptions for Patients With Lower Limb Trauma Requiring Brace or castING.
Non-surgical traumas to the lower limbs that require orthopedic immobilisation (plaster or splint) are a frequent reason for going to accident and emergency.
- Conditions
- Lower Limb Trauma, Venous Thromboembolism, Stratification
- Trial name
- CASTING (NCT04064489)
- Testing
- TRIPscore
- Where
- 15 sites in Belgium, France
- Volunteers
- 2,123 people
- Sponsor
- University Hospital, Angers
Restraint, Physical, Aged
Siderails as a Measure of Physical Restraint. GERBAR Trial
There is a controversy about if siderails should be considered as a method of physical restraint in older hospitalized patients.
- Conditions
- Restraint, Physical, Aged, Aged, 80 and Over, Patient Safety
- Trial name
- GERBAR (NCT04861025)
- Where
- Spain
- Volunteers
- 355 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Antithrombotics Prescriptions
A Prescription Support Tool for Oral Antithrombotic Combinations
From a systematic review of international guidelines (2012-2018), a prescription support-tool synthesizing national and international guidelines on chronic management (≥ 1 month) of oral AT agents without considering in-hospital…
- Trial name
- COMBI-AT (NCT03630874)
- Testing
- Evaluate the impact of a prescription support tool
- Volunteers
- 478 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Pain, Knee Chondroplasty
A Randomized Double-Blind Placebo Controlled Trial to Determine the Status of Post Knee Chondroplasty Patients Administered Theramine Versus Placebo in Addition to Post Surgery Analgesics
The purpose of this study will be to show the patient response to analgesics taken post surgery when taken in combination with Theramine as opposed to Theramine-like placebo.
- Trial name
- NCT01534286
- Testing
- Theramine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Targeted Medical Pharma
Percutaneous Coronary Intervention, Myocardial Infarction
Exercise Prescription in Cardiac Rehabilitation
Cardiac Rehabilitation (CR) is an effective exercise-based lifestyle therapy for patients with cardiac disease. There are two common methods of exercise prescription, an effort based exercise prescription and target heart rate…
- Conditions
- Percutaneous Coronary Intervention, Myocardial Infarction, Coronary Artery Bypass Graft
- Trial name
- NCT03925493
- Testing
- Graded Exercise Stress test (GXT) with Target Heart Rate Range, Heart rate monitors
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Baystate Medical Center
Pain, Postoperative, Orthognathic Surgery
Personalization of Opioid Prescription Following Orthognathic Surgery
This study aims to investigate pain management and satisfaction following orthognathic surgery, which is a type of surgery that corrects jaw and facial bone issues.
- Conditions
- Pain, Postoperative, Orthognathic Surgery, Opioid Use, Patient Satisfaction
- Trial name
- NCT05708521
- Testing
- Personalization of dose and frequency and instituting a tapering protocol of hydromorphone post-orthognathic surgery, Standardized dose and frequency of hydromorphone with no tapering post-orthognathic surgery
- Where
- Canada
- Volunteers
- 201 people
- Sponsor
- Nova Scotia Health Authority
Respiratory Tract Infections, Urinary Tract Infections
Intervention Study to Improve Antibiotic Prescription in Outpatient Care
Antimicrobial resistance has become a world-wide problem and antibiotic consumption is a major driving force for the development of resistance.
- Trial name
- SAPI (NCT01358916)
- Testing
- Mailing of antibiotic therapy guidelines to the sentinel physicians
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University of Bern
Drug Overdose
Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. The annual death toll from overdose is about 250, higher than road traffic accidents.
- Trial name
- OPI-14-001 (NCT02307721)
- Testing
- Intranasal naloxone, Intramuscular naloxone, Remifentanil
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Modality of Discharge Instructions
Effect of Modality on Discharge Instruction in Patients Receiving Outpatient Antibiotic Prescriptions From the Emergency Department
Outpatient antibiotics are frequently prescribed from the emergency department, and limited health literacy may impact compliance with recommended treatments.
- Trial name
- NCT01775969
- Testing
- Text Message, Voicemail
- Where
- United States
- Volunteers
- 2,874 people
- Sponsor
- Hennepin Healthcare Research Institute
Opioid Overdose, Drug Overdose
Preventing Overdose Using Information and Data From the Environment
The objectives of this project are to leverage surveillance data to predict future overdose outbreaks, and to evaluate the impact of a randomized, statewide, community-level intervention trial to target overdose prevention…
- Trial name
- PROVIDENT (NCT05096429)
- Testing
- PROVIDENT
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Brown University
Malaria
Sustainable Financial Incentives To Improve Prescription Practices For Malaria
This project aims to test an innovative, sustainable financial incentive designed to reduce the number of non-malarial fevers that are treated inappropriately with antimalarial drugs.
- Trial name
- NCT01809873
- Testing
- Performance based incentives
- Where
- Kenya
- Volunteers
- 14,862 people
- Sponsor
- Duke University
Heart Failure
Beta-Blockers in Heart Failure: Pharmacy-level Intervention Comparison
The overall objective of the proposed pilot study is to begin evaluation of two methods for promoting adherence to guidelines for beta-blocker therapy in heart failure.
- Trial name
- NCT01002456
- Testing
- Level 1: (provide site-specifi information), Level 2 (Provide site- and patient-specific information)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- US Department of Veterans Affairs
Venous Thromboembolism
Prescription and Utilization of Low Molecular Weight Heparin in Usual Medical Practice for the Curative Treatment of Venous Thromboembolism in Patients With Cancer
The study purpose is to document the prescription and the use of Low Molecular Weight Heparin in usual medical practice in patients with cancer and established Venous Thromboembolism.
- Trial name
- NCT01803022
- Where
- France
- Volunteers
- 419 people
- Sponsor
- LEO Pharma
Knee Osteoarthritis
Exercise and Physical Fitness for Persons With Knee Osteoarthritis
The purpose of this project is to establish evidence to support specific, targeted exercise and rehabilitation recommendations for people over 50 with osteoarthritis of the knee.
- Trial name
- NCT00265447
- Testing
- Strength training, Aerobic conditioning, Delayed exercise
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Acetaminophen Overdose, Pain
Investigation of Efficacy of Improved Acetaminophen Labeling
The purpose of this study is to evaluate, through brief, one-on-one cognitive interviews, the efficacy of 'enhanced' acetaminophen messages and icons in improving consumer understanding and use of prescription (Rx) and…
- Trial name
- NCT01592448
- Testing
- Active Ingredient Icon
- Where
- 4 sites in United States
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- Northwestern University
High Blood Pressure
Produce Prescription for Healthy Blood Pressure
The investigators want to understand the effects of the Produce Prescription for Healthy Blood Pressure program on blood pressure control and people's health.
- Trial name
- PRxBP (NCT07648758)
- Testing
- Produce Prescription for Healthy Blood Pressure (PRx-BP) program
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Texas A&M University
Coronary Artery Bypass
Prospective Cohort Study on Fuzheng Yangxin Prescription For Rapid Rehabilitation of Patients With Qi-Yin Deficiency Syndrome After Coronary Artery Bypass Grafting
Data from the Global Burden of Disease Study 2021, recently published in the Lancet, show that ischaemic heart disease remains the first most common cause of death worldwide.
- Trial name
- NCT06961136
- Testing
- Fuzheng Yangxin prescription
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Opioid Use, Opioid-Related Disorders
Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients
Risk of long-term opioid dependence increases with initial opioid dose/duration, but despite recent Centers for Disease Control and Prevention (CDC)-endorsed minimum doses for initial opioid prescription, primary care providers…
- Conditions
- Opioid Use, Opioid-Related Disorders, Opioid Abuse, Prescription Drug Abuse and Dependency
- Trial name
- NCT03377855
- Testing
- Default Prescribing Change
- Where
- 2 sites in United States
- Volunteers
- 948 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Antibiotic Prescription
Prescription Pattern and Awareness About Antibiotic Prophylaxis and Resistance
To assess the knowledge of Pediatric dentists regarding the prescription of antibiotics, antibiotic prophylaxis and antibiotic resistance
- Trial name
- NCT04031443
- Where
- Egypt
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Cairo University
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