Clinical trials: Prescription
Medication Abuse, Harm Reduction
Clinical Decision Support to Improve System Naloxone Co-prescribing
The objective of this study is to evaluate the impact of a clinical decision support (CDS) alert to facilitate the co-prescribing of naloxone, an opioid overdose reversal agent, with high-risk opioid prescriptions.
- Conditions
- Medication Abuse, Harm Reduction, Opioid Overdose, Opioid Prescribing
- Trial name
- NCT06271668
- Testing
- Naloxone Co-prescribing Clinical Decision Support (CDS)
- Where
- United States
- Volunteers
- 114,272 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Breast Neoplasms
Exercise in Women at Risk for Breast Cancer
This 2-part study will examine how much exercise people usually do in the course of their daily lives and how two different types of exercise-stretching and walking-affect the amount of fat in the body and certain hormones in the…
- Trial name
- NCT00092950
- Testing
- Physical activity
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- National Cancer Institute (NCI)
Delirium
The Effect of Clonidine-enhanced Sedation on Delirium in Ventilated Critically Ill Patients
Rationale: Delirium is highly prevalent in the ICU. GABA-ergic anaesthetics may provoke delirium. Alpha-2-adrenergic agonists may lead to a reduction of the total amount of GABA-ergic anaesthetics and reduction of delirium.
- Trial name
- CATAPRES (NCT01876355)
- Testing
- Clonidine, SodiumChloride
- Where
- Netherlands
- Volunteers
- 115 people
- Sponsor
- Deventer Ziekenhuis
Undernutrition
The ONSHUG Survey : A Quality Care Programme
Hypothesis : At hospital discharge for home, the medical prescription of ONS according to the official criteria of SSNC and the legal regulations (completed prescription according to health's insurance and homecare delivery)…
- Trial name
- NCT02476110
- Testing
- Oral nutritive supplements
- Where
- Switzerland
- Volunteers
- 416 people
- Sponsor
- University Hospital, Geneva
Patients, Programming Languages
Designing a Programming Language for Patient-Oriented Prescriptions
The purpose of this study is to create a human-readable and executable computer language to implement medical prescriptions and to evaluate and refine this language, with the goal of improving safety and efficacy of patient care.
- Trial name
- POP-PL (NCT02820168)
- Where
- 2 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Metabolic Syndrome X, Diabetes Mellitus, Type 2
Evaluation of Effect of Exercise on Prescription
The purpose of this study is to evaluate the effect of a primary healthcare intervention called 'Exercise on Prescription' aimed at increasing level of physical activity in a population of sedentary patients with increased risk…
- Conditions
- Metabolic Syndrome X, Diabetes Mellitus, Type 2, Cardiovascular Diseases
- Trial name
- NCT00399997
- Testing
- Exercise on Prescription
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Southern Denmark
Drug Overdose, Virtual Reality
Use of Virtual Reality for Overdose Management Educational Trainings
This cluster-randomized trial will compare changes in attitudes and knowledge on administering naloxone based on exposure to either a virtual reality educational training or the current standard educational trainings (e.g.
- Trial name
- NCT04091659
- Testing
- Virtual Reality Education, Standard Education
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
All English Speaking Adults From the Manhattan VA Clinic Who Have Recently Received Their First Prescription for a Statin
Does Statin Initiation Undermine Dietary Behavior?
The purpose of this research is to improve our understanding of the effects that taking cholesterol reducing pills have on dietary behavior as well as other health related behaviors
- Trial name
- NCT00224159
- Testing
- Drug and Dietary behavior
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Weill Medical College of Cornell University
Opioid Overdose
Preventing Opioid Overdose Deaths by Empowering Pharmacists to Dispense Naloxone
Objectives: The purpose of this study was to assess the impact of the Empowering Community Pharmacists program on pharmacists' knowledge, perceived barriers, attitudes, confidence, and intentions regarding naloxone services…
- Trial name
- NCT05093309
- Testing
- Educational Webinar, Resources, Reminders
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Auburn University
Infection
Do Fair Comparisons or Harms Data Increase Responsiveness to Feedback About Antibiotic Prescribing: 2x2 Factorial Trial
Antibiotic overuse is common and antibiotic prescribing contributes to rising rates of antimicrobial resistance. Primary care physicians prescribe the majority of all antibiotics and there is large inter-physician variability in…
- Trial name
- NCT04594200
- Testing
- Audit and Feedback (A&F)
- Where
- Canada
- Volunteers
- 5,107 people
- Sponsor
- Women's College Hospital
Acute Pain
Reducing Pain From Wisdom Molar Extractions
This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third…
- Trial name
- NCT05335070
- Testing
- Temporo-masseteric Nerve Block
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rutgers, The State University of New Jersey
Gestational Diabetes, Cardiovascular Risk Factors
Autonomic Nervous System and Exercise In Gestational Diabetes
The focus of this study is on individualized exercise prescription on primary prevention of cardiovascular diseases (CVD). Special attention is set on autonomic nervous system function and inflammation.
- Trial name
- ANS-EXE (NCT01675271)
- Testing
- individual exercise, general exercise
- Where
- Finland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Pain, Chronic Disease
Medication Adherence Therapy for Opioid Abusing Pain Patients
The purpose of this study is to develop and pilot test a combined behavioral and pharmacological intervention designed to decrease pain, functional interference, and drug abuse while increasing medication adherence.
- Conditions
- Pain, Chronic Disease, Prescription Opioid Abuse
- Trial name
- NCT00249587
- Testing
- Methadone
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Malignant Neoplasm, Pain
Survey of Cancer Patients' Perceptions of Difficulties Encountered When Filling Opioid Prescriptions
This trial studies the problems that cancer patients face when filling prescriptions for opioids (medications that are used to manage pain). Pain is one of the most common symptoms among cancer patients.
- Trial name
- NCT03989128
- Testing
- Medical Chart Review, Survey Administration
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- M.D. Anderson Cancer Center
Overdose, Risk Behavior
The Impact of Co-Dispensing Naloxone to Patients Prescribed Chronic Opioid Therapy
In the setting of naloxone standing orders, this study will assess if co-dispensing naloxone with opioids to patients prescribed chronic opioid therapy changes opioid risk behaviors, increases naloxone uptake, and increases…
- Trial name
- NCT03337100
- Testing
- Co-Dispensing
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Kaiser Permanente
Drug Overdose
Virtual Overdose Response
To help prevent deaths in populations that cannot or will not access physical safer consumption services in Alberta, which may disproportionately include women and those who are not able to self-inject (Potier et al., 2014) the…
- Trial name
- NCT04391192
- Testing
- Virtual Overdose Response
- Where
- Canada
- Sponsor
- AHS Cancer Control Alberta
Ankle Injuries, Nurse's Role
Early Prescription of Radiography Using the Ottawa Ankle Rules by a Nurse in the Management of Isolated Ankle Trauma
The study will be conducted in 2 phases (A and B) using two different groups of patients in order to prove that an early prescription of radiography using the Ottawa Ankle Rules by a nurse practitioner could shorten length of…
- Conditions
- Ankle Injuries, Nurse's Role, Emergencies
- Trial name
- PARIAO (NCT04021511)
- Testing
- OAR application by a nurse
- Where
- France
- Volunteers
- 63 people
- Sponsor
- Centre Hospitalier de Saint-Brieuc
Heart Failure
Can Diagnostics and Pharmacological Prescriptions in Patients With Heart Failure be Improved in General Practice?
This study will explore the possible effect of a tailored educational intervention towards general practitioners in Norway, in order to improve the quality of treatment for heart failure in general practice.
- Trial name
- NCT01476566
- Testing
- Educational intervention
- Sponsor
- University of Oslo
Cerebral Amyloid Angiopathy
Jiedu Huayu Oral Prescription in the Treatment of Intracranial Hemorrhage Associated With Cerebral Amyloid Angiopathy
Cerebral hemorrhage, as a serious cerebrovascular disease, has the highest disability rate and mortality rate among all types of cerebrovascular diseases .It has brought a heavy burden to society.
- Trial name
- CHN-CAA (NCT07250035)
- Testing
- Jiedu Huayu Oral Prescription
- Where
- China
- Volunteers
- 436 people
- Sponsor
- Beijing Tiantan Hospital
Diabetes Mellitus, Type 2, Hypertension
Impact of Bilingual Prescription Medication Labels Among Elderly Singaporeans
The proposed study aims to provide preliminary data that will enable the conduct of a larger Randomized Controlled Trial (RCT) on the impact of bilingual Prescription Medication Labels (PMLs) on 3 medication-related outcomes …
- Trial name
- NCT05101330
- Testing
- Bilingual prescription medication labels
- Where
- Singapore
- Sponsor
- Singapore General Hospital
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