Clinical trials: Prescription
Diabetes Mellitus, Type 2
The Prescription Patterns and Clinical Efficacy of Tenero Tab/Tenero M SR Tab
This study is to observe the prescription patterns and clinical efficacy of patients prescribed with Tenero Tab/Tenero M SR Tab for diabetes treatment in routine clinical practice.
- Trial name
- NCT06188234
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Esophagus Cancer
Clinical Trial of Qizhu Yuling Prescription in the Prevention and Treatment of Esophagus Cancer
The purpose of this study is to evaluate the efficacy and safety of Qizhu Yuling prescription for postoperative esophagus cancer.
- Trial name
- NCT05626309
- Testing
- Qizhu Yuling Prescription
- Where
- 3 sites in China
- Volunteers
- 310 people
- Sponsor
- Jie Li
Treatment
Digital Coaching With" Physical Activity on Prescription ( FaR) to Increase Physical Activity and Reduce Post Stroke Fatigue
Stroke is the leading cause in the world considering disabilities and approximately half of the patient population experience post stroke fatigue (PSF). PSF affects the patients level of activity and their quality of life.
- Trial name
- NCT05573867
- Testing
- Physical activity on prescription
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Region Gävleborg
Hypertension With Complications and Secondary Hypertension, Overweight and Obesity
Study of the Long-term Effects of Exercise on Heath Indicators in Older People
Cardiovascular diseases (CVD) represent the most frequent cause of death among the elderly population. Hypertension, unfavorable lipid profile, obesity and physical inactivity are among the main risk factors for CVD.
- Conditions
- Hypertension With Complications and Secondary Hypertension, Overweight and Obesity, Lipid Metabolism Disorders, Sarcopenia
- Trial name
- NCT01874132
- Testing
- Exercise training
- Where
- Portugal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Trás-os-Montes and Alto Douro
Acne Vulgaris
Comparing OTC Acne Treatment to Prescription Regimen
This research is being done to find out the safety and efficacy of two acne creams, Effaclar and Benzaclin when used twice daily with a topical retinoid. Effaclar and Benzaclin are FDA approved for the treatment of acne.
- Trial name
- NCT01237821
- Testing
- BenzaClin, Effaclar
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Mild Cognitive Impairment, Elderly
Medication Misuse and Dependence Among Elderly
The project focuses on investigating problematic medication use, especially overuse of potentially addictive drugs among the elderly.
- Conditions
- Mild Cognitive Impairment, Elderly, Substance-Related Disorders
- Trial name
- NCT03162081
- Testing
- Substance misuse screening, EQ-5D, Impulsivity screening
- Where
- Norway
- Volunteers
- 500 people
- Sponsor
- University Hospital, Akershus
Opioid Overdose
Project OOPEN: Opioid Overdose Prevention, Education and Intervention
This prospective, randomized emergency department trial will study the effectiveness of an intervention that combines opioid overdose prevention, education and intervention that includes take home naloxone with brief behavioral…
- Trial name
- OOPEN (NCT01788306)
- Testing
- OOPEN+BBCC
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- University of Washington
Diabetes Mellitus, Type 2, Hypertension
Impact of Bilingual Prescription Medication Labels Among Elderly Singaporeans
The proposed study aims to provide preliminary data that will enable the conduct of a larger Randomized Controlled Trial (RCT) on the impact of bilingual Prescription Medication Labels (PMLs) on 3 medication-related outcomes …
- Trial name
- NCT05101330
- Testing
- Bilingual prescription medication labels
- Where
- Singapore
- Sponsor
- Singapore General Hospital
Post-cardiac Surgery, Rehabilitation
Aerobic Reconditioning After Cardiac Surgery Using a Predictive Exercise Model
Brief Summary After heart surgery, aerobic exercise is essential for recovery. Traditional exercise planning uses a cardiopulmonary exercise test (CPET), which may be unavailable early after surgery.
- Trial name
- NCT07440407
- Testing
- Equation-Based Aerobic Exercise Prescription, Symptoms-Based Aerobic Exercise Prescription
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Type 2 Diabetes Mellitus, Hypertension
Grocery Prescription Program for Medicaid Adults With Hypertension or Type 2 Diabetes
The purpose of this study is to evaluate the effectiveness of a grocery prescription program in adults diagnosed with either Type 2 Diabetes Mellitus or Hypertension. Participants will enroll in Instacart Fresh Funds program.
- Trial name
- NCT06033664
- Testing
- Fresh Funds
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Alison Gustafson
Malocclusion, Malocclusion, Angle's Class
Precision Orthodontics: Virtual Treatment Planning for Orthodontic Braces
The investigators are evaluating the effectiveness of custom-made 3D-printed ceramic (tooth-colored) brackets (braces) compared to conventional tooth-colored brackets (braces).
- Trial name
- NCT04002999
- Testing
- 3D printed ceramic bracket and tray, Stock ceramic bracket + 3D printed tray, Stock bracket, no tray
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Parkinson
123 I-FP-CIT SPECT Prescriptions for Parkinsonian Syndromes
123I-FP-CIT SPECT (DaTSCAN®) allows to detect presynaptic dopamine neuronal denervation. It is recommended to differentiate neurodegenerative parkinsonism from secondary parkinsonian syndromes or from essential tremor, and to…
- Trial name
- NCT05698784
- Where
- France
- Volunteers
- 723 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Overdose
SOONER Feasibility Study Protocol
Opioid Overdose Education and Naloxone Distribution programs (OEND) involve training and equipping people who are likely to be bystanders to opioid overdose to recognize and respond to opioid-related emergencies by activating…
- Trial name
- SOONER (NCT03821649)
- Testing
- SOONER Training and Naloxone Kit Kit, Community or Hospital-Based Training
- Where
- 4 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Arterial Hypertension
"Community-based, eHealth Supported Management of Cardiovascular Risk Factors by Lay Village Health Workers (ComBaCaL aHT TwiC 1 & ComBaCaL aHT TwiC 2)
ComBaCaL aHT TwiC 1 and aHT TwiC 2 are two cluster-randomized controlled trials that are identical in intervention, design and endpoints.
- Trial name
- NCT05684055
- Testing
- First-line antihypertensive single-pill combination (SPC), Standardized counselling and referral to the closest health facility
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 1,354 people
- Sponsor
- University Hospital, Basel, Switzerland
Medication Abuse, Harm Reduction
Evaluation of Clinical Decision Support in Opioid Tapering
The 2022 Center for Disease Control and Prevention (CDC) clinical practice guideline for prescribing opioids for pain recommends that when tapering a patient's opioid dose, doses should be decreased at a slow rate to reduce the…
- Conditions
- Medication Abuse, Harm Reduction, Opioid Use Disorder, Opioid Prescribing
- Trial name
- NCT06527079
- Testing
- Observational study without a prospective intervention
- Volunteers
- 200,000 people
- Sponsor
- University of Colorado, Denver
Cardiac Rehabilitation, Exercise Therapy
Exercise Prescription in Cardiac Rehabilitation Mediated by Autonomic Function
Cardiac rehabilitation (CR) is an essential secondary prevention component in the treatment of cardiovascular diseases and one of the most cost- effective clinical interventions.
- Conditions
- Cardiac Rehabilitation, Exercise Therapy, Autonomic Nervous System Imbalance, Treatment Outcomes
- Trial name
- EXCARMA (NCT07288840)
- Where
- 2 sites in Portugal
- Volunteers
- 90 people
- Sponsor
- Instituto Politécnico de Leiria
Drug Overdose
Pharmacodynamics and Arteriovenous Differences of Naloxone in Healthy Participants Exposed to an Opioid
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. To save lives, immediate treatment with a μ-opioid antidote such as naloxone is required.
- Trial name
- OPI-15-001 (NCT02405988)
- Testing
- Intravenous naloxone, Remifentanil
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Psychiatric Disorder
Prescription of Valproate and Derivatives in Women of Childbearing Age: Qualitative Study
The prescription of valproate in women of childbearing age has decreased by 82% in France, for mood disorders. Exposure to valproate during pregnancy 60%.
- Trial name
- VALPRO (NCT06499779)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Drug Overdose, Opioid Withdrawal
Feasibility of the Utilization of Buprenorphine in the Emergency Room to Treat Clinical Opioid Withdrawal
The investigators are trying to determine whether they can effectively treat patients suffering from acute opioid withdrawal in the Emergency Department at Virginia Commonwealth University Health System (VCUHS) and subsequently…
- Conditions
- Drug Overdose, Opioid Withdrawal, Opioid-use Disorder
- Trial name
- NCT03489161
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Virginia Commonwealth University
Obesity, Appetite Disorders
Impact of a Satiating Diet in Obese Men With a Low Satiety Phenotype
The global research project was organized as a clinical process starting with an evaluation aiming at the determination of a diagnosis pertaining to the degree of satiety signal capacity.
- Trial name
- NCT03128697
- Testing
- Satiating diet, Control diet
- Where
- 2 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laval University
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