Clinical trials: Prescription
Hypertension ,Pregnancy, Diabetes During Pregnancy
Impact of Exercise Prescription on Obstetric and Neonatal Outcomes
The aim of this study is to assess the impact of structured physical activity with smartwatch remote monitoring on glycemic control, blood pressure control, obstetric complications and neonatal outcomes in women with GDM, chronic…
- Conditions
- Hypertension ,Pregnancy, Diabetes During Pregnancy, Obesity (BMI>30)
- Trial name
- NCT07678944
- Testing
- Physical activity plan, Women who received information but did not engaged in a physical activity routine
- Where
- Portugal
- Volunteers
- 310 people
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Overdose, Drug Abuse
Naloxone Nasal Spray Compared With Naloxone Injection for Opioid Overdoses Outside the Hospital
This trial will compare the clinical response to intramuscular and intranasal naloxone in pre-hospital opioid overdoses. Objective of the study is to measure and evaluate clinical response (return of spontaneous respiration…
- Trial name
- NINA-1 (NCT03518021)
- Testing
- Naloxone, intranasal, Naloxone, intramuscular
- Where
- 2 sites in Norway
- Volunteers
- 286 people
- Sponsor
- Norwegian University of Science and Technology
Stage IV Lung Cancer
Truthful Information on Chemotherapy and Its Impact on Chemotherapy at the End of Life
Patients with metastatic cancer have a substantial symptom burden and may receive aggressive care at the end of life. There is evidence that the use of chemotherapy near the end of life is not related to its likelihood of…
- Trial name
- HIPPOCRATE (NCT02606149)
- Testing
- Truthful information on chemotherapy risks, Standard of information
- Where
- France
- Volunteers
- 123 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Failure, Patient Acceptance of Health Care
Intensive Education Versus Usual Education of Patients for Improving Guideline Directed Medical Therapy (GDMT) Prescription in Heart Failure With Reduced Ejection Fraction
The goal of this randomized clinical trial is to test the effect of patient education on extent of use of guideline directed medical treatment (GDMT) of heart failure with reduced ejection fraction.
- Trial name
- NCT06273085
- Testing
- Patient education
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Medstar Health Baltimore
Exercise Therapy, Behavior and Behavior Mechanisms
Health-Enhancing Adapted Physical Activity Program at "Mon Stade"
Introduction: Regular practice of exercise or physical activity (PA) is a recognized intervention as a determinant of good health acquisition, maintenance, or recovery for a large number of chronic pathologies.
- Conditions
- Exercise Therapy, Behavior and Behavior Mechanisms, Adherence, Patient, Lifestyle, Sedentary
- Trial name
- SESAME (NCT04716322)
- Testing
- Adapted Physical Activity
- Where
- France
- Volunteers
- 2,024 people, healthy volunteers welcome
- Sponsor
- Mon Stade Sports Medicine Centre
Lower Resp Tract Infection
Effect of Pediatric Lung Ultrasound on Antibiotic Prescriptions in Hospitalized Children and Adolescents With Lower Respiratory Tract Infections. A Randomized Controlled Trial.
Title: Effect of Pediatric Lung Ultrasound on Antibiotic Prescriptions in Hospitalized Children and Adolescents with Lower Respiratory Tract Infections (PLUS-AP Trial) Purpose of the Study: This study is being done to find out if…
- Trial name
- PLUS-AP (NCT06876766)
- Testing
- Lung Ultrasound
- Where
- Lebanon
- Volunteers
- 176 people
- Sponsor
- American University of Beirut Medical Center
Insomnia Chronic
Prescription Digital Therapeutic for the Treatment of Insomnia
This will be a prospective multi-center controlled trial of 100 patients conducted to assess the real-world effectiveness of a mobile-delivered, prescription digital therapeutic (PDT) device delivering Cognitive Behavioral…
- Trial name
- SLEEP-I (NCT04909229)
- Testing
- PEAR-003b PDT Intervention, Fitbit, Sleep education materials
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Head and Neck Neoplasms, Carcinoma, Squamous Cell
Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity
The objective of the UPGRADE-RT trial is to investigate whether de-escalation of elective radiation dose and introduction of an intermediate dose-level in the treatment of head and neck cancer will results in less radiation…
- Trial name
- UPGRADE-RT (NCT02442375)
- Testing
- standard dose prescription, FDG-PET guided gradient dose prescription
- Where
- 5 sites in Netherlands
- Volunteers
- 300 people
- Sponsor
- Radboud University Medical Center
Chronic Pain
Increased Sensitivity to Pain Caused by Opioids in People Who Have Abused Prescription Opioids
Managing pain in patients who abuse prescription opioids presents many challenges, including the development of opioid-induced hyperalgesia (OIH).
- Trial name
- NCT01821430
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Georgetown University
Hypertension, Dyslipidemia
A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for clinicians to use to…
- Conditions
- Hypertension, Dyslipidemia, Diabetes Mellitus, Obesity
- Trial name
- P3-EX (NCT07238556)
- Testing
- Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants, Active Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Connecticut
Cancer Patients, Cancer-related Pain
A Consensus on Opioid Prescription for Oncologic Patients in Latin America - A DELPHI Study.
As seen worldwide, cancer incidence is increasing in Latin America achieving an amount of 1.3 million new cases annually.1 In addition, it is expected that up to 70% of patients with cancer will experience pain2, one of the most…
- Trial name
- NCT04844788
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Opiate Substitution Treatment
Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence
This is a randomized trial of two group-based models of care for buprenorphine/naloxone (bup/nx) patients in Substance Use (SU) specialty treatment: Standard Medical Management (SMM) and Intensive Outpatient Treatment (IOT).
- Trial name
- NCT02496403
- Testing
- Standard Medical Management (SMM)
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- Kaiser Permanente
Viral Gastro Enteritis, Pharyngitis
Impact of Handing to Patients a Copy of the Consultation Report on Their Medicine Consumption
In France, patients with benign viral infections (ie: gastro enteritis and/or rhinopharyngitis, etc.) often receive several prescriptions from their doctors, although there is evidence that these medicines are not efficient.
- Trial name
- NCT02237573
- Testing
- Written medical report and standardized medical advices, Control
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Paris 7 - Denis Diderot
Oral Lichen Planus, Recurrent Aphthous Stomatitis
Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led Model
This study aims to improve how oral mucosal disorders-such as oral lichen planus, recurrent aphthous stomatitis, burning mouth syndrome, herpes viral infection and oral candidiasis-are treated in dental settings.
- Conditions
- Oral Lichen Planus, Recurrent Aphthous Stomatitis, Burning Mouth Syndrome, Oral Candidiasis
- Trial name
- NCT07721090
- Testing
- Pharmacist-Led Prescribing Optimization and Patient Counselling
- Volunteers
- 336 people
- Sponsor
- University of Fujairah
Patients, Programming Languages
Designing a Programming Language for Patient-Oriented Prescriptions
The purpose of this study is to create a human-readable and executable computer language to implement medical prescriptions and to evaluate and refine this language, with the goal of improving safety and efficacy of patient care.
- Trial name
- POP-PL (NCT02820168)
- Where
- 2 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HIV Testing, STI
HIV/STI/HCV Testing and Overdose Prevention Among Survivors of Sex Trafficking
This project will assess whether a digital survivor crowdsourced intervention can increase HIV/STI/HCV testing and overdose prevention kit utilization among survivors of sex trafficking living in New York City.
- Conditions
- HIV Testing, STI, HCV, Overdose, Drug
- Trial name
- NCT07264582
- Testing
- Sex Trafficking Survivor-Developed Digital Crowdsourced Intervention
- Where
- United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Columbia University
Inflammatory Responses
Effects of a Prescription Omega-3 Fatty Acid Concentrate on Induced Inflammation
The purpose of this study is to assess whether the marine omega-3 fatty acids can attenuate inflammatory responses to endotoxin challenge.
- Trial name
- PRONOVA (NCT01813110)
- Testing
- 4 g prescription omega-3 concentrate
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Penn State University
Coronary Arterial Disease (CAD)
Effects of Heart Rate Variability-guided Training vs Standard Aerobic Prescription on Cardiovagal Modulation and Cardiorespiratory Fitness in Coronary Artery Disease
Coronary artery disease (CAD) is associated with autonomic dysfunction and is characterized by reduced heart rate variability (HRV) and impaired heart rate recovery.
- Trial name
- ParaDox (NCT06919237)
- Testing
- HIIT Intervention, MICT Intervention, HRV-Guided Intervention
- Where
- Portugal
- Volunteers
- 48 people
- Sponsor
- Faculdade de Motricidade Humana
Obesity
Comparing a Virtual vs. Face to Face Weight Management Program Using Phentermine for Patients With Overweight or Obesity
This study will study the effects associated with the prescription of phentermine in a virtual setting, comparing with prescription of phentermine via a standard face-to-face visit for patients with obesity or overweight.
- Trial name
- NCT04614545
- Testing
- Phentermine 37.5 Mg, Dietary program, Exercise program
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Cleveland Clinic
Opioid Abuse, Overdose
Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders
In the setting of naloxone standing orders, this study will assess if direct outreach with a web-based "Naloxone Navigator 1.0" to patients prescribed chronic opioid therapy (COT) changes opioid risk behaviors, increases naloxone…
- Conditions
- Opioid Abuse, Overdose, Risk Behavior
- Trial name
- NCT03241771
- Testing
- Naloxone Navigator 1.0
- Where
- United States
- Volunteers
- 325 people
- Sponsor
- Kaiser Permanente
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