Clinical trials: Prescription
Opioid Overdose, Drug Overdose
Preventing Overdose Using Information and Data From the Environment
The objectives of this project are to leverage surveillance data to predict future overdose outbreaks, and to evaluate the impact of a randomized, statewide, community-level intervention trial to target overdose prevention…
- Trial name
- PROVIDENT (NCT05096429)
- Testing
- PROVIDENT
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Brown University
Opioid Dependence
Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse
In this study, we will assess opioid self-administration in a laboratory setting in persons with pain who have a history of opioid abuse.
- Trial name
- PAIN (NCT01967641)
- Testing
- buprenorphine/naloxone combination
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- New York State Psychiatric Institute
Opioid Use, Sedative Use
Prescription Medication Interactions
This study will examine the effects of doses of opioid/placebo and doses of sedative/placebo, alone and in combination. The primary outcomes are related to pharmacodynamic measures (subjective ratings of drug liking and other…
- Trial name
- NCT04315181
- Testing
- Opioid Agonist, Sedatives
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Sharon Walsh
Substance Use, HIV Infections
Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)
This study will test the effects of an intervention to reduce substance use and related harms among people leaving rural jails or otherwise involved in the criminal justice system.
- Conditions
- Substance Use, HIV Infections, HCV Infection, Sexually Transmitted Infections (Not HIV or Hepatitis)
- Trial name
- NCT04134767
- Testing
- Health Linkage, Overdose Education
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- April M Young
Low Back Pain
Spinal Manipulation Services vs. Prescription Drug Therapy for Long-term Care
Our overall objective is to assess the value of Spinal Manipulation Services as compared to Prescription Drug Therapy for long-term management of chronic Law back Pain (LBP).
- Trial name
- NCT03669354
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Southern California University of Health Sciences
Prescription Drug Insurance Decision Making
Evaluating a Patient-Centered Tool to Help Medicare Beneficiaries Choose Prescription Drug Plans
The objective of this study is to determine whether providing Medicare beneficiaries with a web-based patient-centered decision tool to help them choose among prescription medication coverage plans improves outcomes for patients…
- Trial name
- CHOICE (NCT02895295)
- Testing
- Expert Recommendation, Individual Analysis, Usual Care
- Volunteers
- 1,185 people
- Sponsor
- Stanford University
Substance Withdrawal Syndrome
Efficacy of Extended Release Tramadol for Treating Prescription Opioid Withdrawal
Prescription opioid addiction is a growing public health problem and more pharmacologic treatments are needed because current approved medications have had limited patient acceptance (naltrexone), limited availability…
- Trial name
- NCT00980044
- Testing
- Tramadol
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Michelle Lofwall
Suicide, Overdose Accidental
Pilot of Training on 988 and Narcan
This pilot study evaluates the acceptability, appropriateness, and feasibility of a new crisis response training called Crisis Ready.
- Conditions
- Suicide, Overdose Accidental, Overdose Antidote, Crisis Response Plan
- Trial name
- NCT07072819
- Testing
- Crisis Ready Training
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- RAND
Drug Dependence
Improving Treatment Outcomes for Prescription Opioid Dependence
Overall, this proposal seeks to improve treatment strategies for the significant public health problem of prescription opioid dependence by determining whether gabapentin, a non-narcotic pharmaceutical agent with minimal abuse…
- Trial name
- GBN (NCT02543944)
- Testing
- Gabapentin, Buprenorphine, Clonidine
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Arkansas
Acute Upper Respiratory Tract Infections
Trial of Post-Dated Delayed Antibiotic Prescriptions
Delayed prescriptions have been shown to lower antibiotic use for upper respiratory tract infections (which are mostly viral). This trial will test the hypothesis that if the clinician post-dates the delayed prescription by 2…
- Trial name
- NCT02732847
- Testing
- A delayed prescription dated 2 days after clinical office visit, Usual Dated
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- Memorial University of Newfoundland
Economics, Fraud
The Effect of Informative Letters on the Prescription and Receipt of Schedule II Controlled Substances
Fraud and waste is estimated to cost the American health care system nearly $200 billion each year, and the public Medicare and Medicaid programs about $60 billion each year.
- Conditions
- Economics, Fraud, Delivery of Health Care, Health Expenditures
- Trial name
- NCT02345434
- Testing
- Informative letter
- Volunteers
- 1,525 people, healthy volunteers welcome
- Sponsor
- Abdul Latif Jameel Poverty Action Lab
Drug Overdose, Opioid-Related Disorders
Safety & Prevention Outcomes Study
Unintentional poisoning is a developing public health problem in the U.S. Unintentional poisoning (or "overdose") deaths increased 157% among adults between 1999 and 2008.
- Trial name
- SPOS (NCT01894087)
- Testing
- TBI - Cohort 1, TBI - Cohort 2
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- University of Michigan