Clinical trials: Prescription
Opioid Overdose, Opioid Use Disorder
Safety, Tolerability, and Pharmacokinetics of CSX-1004
This is a Phase 1a, randomized, double-blind, single ascending dose study, designed to assess the safety, tolerability, and PK of a single CSX-1004 injection, administered by IV infusion across a range of doses in healthy adult…
- Trial name
- NCT06005402
- Testing
- CSX-1004
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cessation Therapeutics, Inc.
Asthma
The Predictors for Asthma Control by Stepwise Treatment During 6 Months in Korean Elderly
The Predictors for asthma control by stepwise treatment during 6 months in Korean elderly
- Trial name
- Prelude (NCT01370577)
- Where
- 5 sites in South Korea
- Volunteers
- 297 people
- Sponsor
- AstraZeneca
COPD
Intervention to Reduce Misused Inhaler and Insufficient Peak Inspiratory Flow in Hospitalized COPD Patients
The drug treatment of chronic obstructive pulmonary disease (COPD) is mainly based on inhaled therapy. This route of administration is limited by inhaler handling errors, insufficient inspiratory flow or inappropriate inhalers.
- Trial name
- MIPIF (NCT05207631)
- Testing
- Systematic and standardised assessment of inhalers and implementation of a prescribing guide
- Where
- Switzerland
- Volunteers
- 101 people
- Sponsor
- Hôpital Fribourgeois
Inappropriate Prescribing
Effectiveness of a Community Intervention in the Chronic Use of Benzodiazepines: (BENZOSTOPJUNTOS)
This study aimed to assess the effectiveness of a comprehensive, multicomponent intervention utilizing education and support for Benzodiazepines withdrawal compared to standard care.
- Trial name
- BENZOSTOP (NCT06209827)
- Testing
- Intervention for reducing benzodiazepines long-term use.
- Where
- Spain
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- Andalusian Health Service
Cardiovascular Diseases, Cardiac Rehabilitation
Threshold-Based Versus Range-Based Exercise Intensity Prescription in Cardiac Rehabilitation
Cardiac rehabilitation is an important part of the treatment of patients with cardiovascular disease. Supervised aerobic exercise improves physical fitness, functional capacity, and quality of life.
- Trial name
- T-REXI-CR (NCT07908810)
- Testing
- Threshold-Based Aerobic Exercise Intensity Prescription, Range-Based Aerobic Exercise Intensity Prescription
- Where
- 9 sites in Belgium
- Volunteers
- 230 people
- Sponsor
- Hasselt University
Opioid Overdose
Vaped Marijuana to Attenuate Naloxone-Precipitated Withdrawal
The goal of the proposed, proof-of-concept study is to test the combined effects of vaporized marijuana [Delta-9-tetrahydracannabinol (THC)] with NLX as a proof of concept towards the possible development of a combined overdose…
- Trial name
- NCT05114460
- Testing
- Naloxone, Marijuana
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- New York State Psychiatric Institute
Opioid Use Disorder, Alcohol Use Disorder
Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis
The opioid epidemic has become one of America's deadliest crises, surpassing car crashes, firearms, and HIV/AIDS as a leading cause of death for Americans under fifty years of age.
- Conditions
- Opioid Use Disorder, Alcohol Use Disorder, Health Risk Behaviors, Criminal Behavior
- Trial name
- RB (NCT05665179)
- Testing
- Removing Barriers to Recovery
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- University of Michigan
Antibiotic Side Effect
Antibiotic Prescription for Children With Acute Upper Respiratory Tract Infections in Assiut District
Antibiotics are one of the most commonly prescribed drugs in pediatric care all over the world. Over prescription of antibiotics is a major public health problem and the most important factor in the emergence of antibiotic…
- Trial name
- NCT04127682
- Testing
- Antibiotic KAP questionnaire
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Assiut University
HIV Infections
Comparison of Stavudine Used Alone or in Combination With Didanosine in HIV-Infected Children
To evaluate the safety and determine the pharmacokinetic disposition of stavudine (d4T) alone and in combination with didanosine (ddI), and whether concurrent administration alters the disposition of either drug.
- Trial name
- NCT00000851
- Testing
- Stavudine, Didanosine
- Where
- 35 sites in United States, Puerto Rico
- Volunteers
- 198 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Drug Prescriptions
Effect of an Opioid Disposal Pouch Versus Usual Care on Post Discharge Disposal of Unused Medication
The purpose of the study is to determine if opioid disposal bags/pouches are an effective method for disposing of unused opioid medications postoperatively
- Trial name
- NCT04553588
- Testing
- Disposal pouch
- Where
- United States
- Volunteers
- 313 people
- Sponsor
- The Cleveland Clinic
Children on Chronic Peritoneal Dialysis
Comparing Conventional Continuous Ambulatory Peritoneal Dialysis Prescription (C-CAPD) With Modified-CAPD (M-CAPD) Prescription in Children With End-stage Kidney Disease From Low-resource Settings
This study aims to compare modified CAPD (M-CAPD) and conventional CAPD (C-CAPD) in terms of delivering high-quality, goal-directed PD as well as avoiding resource wastage in prevalent ESKD patients aged 2 to ≤18 years using a…
- Trial name
- NCT07134595
- Testing
- C-CAPD Prescription, M-CAPD Prescription
- Where
- Philippines
- Volunteers
- 44 people
- Sponsor
- National University Health System, Singapore
Opioid Use Disorder
Mobile Peer Support for OUD Recovery
The COVID-19 pandemic puts individuals recovering from opioid use disorders (OUDs), an already vulnerable population, at increased risk of overdose due to decreased access to treatment, decreased social support, and increased…
- Trial name
- MPS (NCT05405712)
- Testing
- Mobile Phone App
- Where
- 2 sites in United States
- Volunteers
- 1,300 people
- Sponsor
- Brown University
SARS-CoV Infection, Antimicrobial Stewardship
Analysis of the Quality and Quantity of Antibiotic Prescriptions for Bacterial Respiratory Tract Superinfection in Patients Hospitalized in COVID-19 Wards
In this prospective observational study, a quantitative and qualitative analysis of antibiotic prescriptions for presumed respiratory tract (super)infection in patients hospitalized on COVID-19 wards will be made.
- Conditions
- SARS-CoV Infection, Antimicrobial Stewardship, Respiratory Tract Infections, Antibiotic Resistance
- Trial name
- NCT04544072
- Where
- Belgium
- Volunteers
- 400 people
- Sponsor
- Universitair Ziekenhuis Brussel
Chronic Disease, Risk Reduction
Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness
The purpose of this study is to examine if and how implementing nature prescriptions can increase time in nature and improve health to yield an actionable understanding of the nature-health connection.
- Conditions
- Chronic Disease, Risk Reduction, Mental Health Wellness 1, Physical Inactivity
- Trial name
- NCT06001697
- Testing
- Park prescription, Regular health advice
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Stanford University
Medication Therapy Management
Impact of a Mobile Geriatric Team With a Pharmacist on the Optimisation of Prescriptions in Elderly Inpatients
In patients aged 75 years and older, polypathology is frequent and often associated with polypharmacy. This polypharmacy coupled with a lack of proactive elderly care can sometimes lead to hospitalisation.
- Trial name
- PHARMOG (NCT04151797)
- Testing
- Medication therapy management
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Toulouse
Cardiovascular Diseases
Implementation of a Pharmacy-Intervention to Enhance Prescription and Use of Lipid-Lowering Drugs
The purpose of this study is to determine the effectiveness of maximal support of community pharmacies to implement a pharmaceutical care model for improving underprescription and treatment persistence regarding lipid-lowering…
- Trial name
- NCT00509717
- Testing
- intensive implementation programme, control
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Radboud University Medical Center
Mild Cognitive Impairment (MCI)
Validation of Population Characteristics and Dosage Prescriptions for Cognitive Function Intervention Benefits of Different Doses of Tai Chi in Elderly Patients With Mild Cognitive Impairment: A Real-World Cross-Sectional Study
This is a companion real-world external validation study of two pre-registered parent randomized controlled trials (RCTs, protocol IDs: FujianUTCM-1 and FujianUTCM-2).
- Trial name
- NCT07608510
- Testing
- 24-form Simplified Tai Chi (Observational Behavioral Exposure)
- Volunteers
- 150 people
- Sponsor
- Lidian Chen
Overdose
A Universal Primary Care Based Intervention to Reduce Youth Overdose Risk
Adolescent (ages 10-19) overdose deaths are the third leading cause of pediatric death and continue to rise in the United States.
- Trial name
- NCT07022717
- Testing
- Brief youth overdose prevention education, Information about Naloxone, Usual standard of care
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston Medical Center
Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use
TAPS-ESP: Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use Electronic Spanish Platform
This Phase 1 STTR project will develop a technology platform for delivering the TAPS Tool to a Spanish-speaking, health disparity population in a community health center.
- Trial name
- TASP-ESP (NCT03879785)
- Testing
- Screening
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Obstructive Sleep Apnea, Overweight and Obesity
Sport as a Treatment in Chronic Diseases and Healthcare Sustainability
Obesity, associated with obstructive sleep apnea (OSA) is often involved in cardiovascular diseases. In our study, we want to promote sport practice to reduce that burden in the first place, and all associated diseases (e.g.
- Trial name
- S4H (NCT03087318)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.