Clinical trials: Prescriptions
Opioid Overdose
Naloxone Nasal Spray Pharmacokinetic Study
This study aims to compare the pharmacokinetics of naloxone when administered as the Mitovie nasal spray (Test Product) and as a solution for injection (Comparator Product) administered intranasally using a mucosal atomization…
- Trial name
- NCT01622504
- Testing
- MVP005, Naloxone hydrochloride solution for injection with mucosal atomization device
- Where
- Jordan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mitovie Pharma Ltd
Children, Exercise
Prescription of Exercise in Children
Most pediatric populations do not meet the physical activity (PA) recommendations set by international organizations. The effectiveness of casual PA advice provided during medical consultations has not been adequately assessed…
- Conditions
- Children, Exercise, Physical Activity, Screen Time
- Trial name
- NCT06765460
- Testing
- Medical prescription of exercise, Health Advice
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital Virgen de las Nieves
Well Being
Group Laughie Intervention for Well-Being in Earthquake Survivors: A Pilot Study
Mental health and quality of life may be negatively impacted among earthquake survivors. This pilot study aims to evaluate the feasibility, acceptability, and potential effects of a 1-minute Laughie (Laugh Intentionally Everyday)…
- Trial name
- NCT07563140
- Testing
- Laughie
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Medication Errors
Outpatient Prescription Errors: Detection, Analysis, and Impact on Safety
The purpose of this study is to better understand outpatient prescribing errors through clinic and pharmacy-based error reporting systems.
- Trial name
- NCT00256568
- Testing
- reporting system
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Primary Gout, Hyperuricemia
Study on the Bioavailability of Three Different Prescription Processes of SHR4640 Tablets in Healthy Volunteers
The primary objective of the study is to evaluate the relative bioavailability of three different prescription processes of SHR4640 tablets in healthy volunteers.
- Trial name
- NCT04586803
- Testing
- SHR4640
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Acute Respiratory Tract Infections
Optimisation of Antibiotic Prescription in Acute Noncomplicated Respiratory Tract Infections in Children (OptimAP Study)
Background: High-volume antibiotic prescribing in primary care is a major driver of antibiotic resistance. Education of physicians and patients can lower prescribing levels, but it frequently relies on highly trained staff.
- Trial name
- OptimAP (NCT05166369)
- Testing
- Communication skills training, Mobile phone application on RTI
- Where
- 4 sites in Spain
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Prescription Practices of Family Physicians in NL
Randomized Controlled Study to Incentivize Doctors for Appropriate Use of Medical Care in NL
Choosing Wisely Canada is a campaign for promoting appropriate use of medical services to reduce unnecessary prescribing and unnecessary diagnostic tests.
- Trial name
- NCT03488121
- Testing
- Poster, Thank-you Letter
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Opioid Overdose
Preventing Opioid Overdose Deaths by Empowering Pharmacists to Dispense Naloxone
Objectives: The purpose of this study was to assess the impact of the Empowering Community Pharmacists program on pharmacists' knowledge, perceived barriers, attitudes, confidence, and intentions regarding naloxone services…
- Trial name
- NCT05093309
- Testing
- Educational Webinar, Resources, Reminders
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Auburn University
Chronic Pain
Treatment, Pain, and Opioids
Background: Chronic pain and negative consequences of long-term opioid therapy are related public health concerns associated with significant functional impairment, high psychiatric comorbidity, and premature mortality…
- Trial name
- NCT05363176
- Testing
- Cognitive-Behavioral Therapy for Treatment Seeking, Pain treatment education
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Pro-inflammatory Activity, Immunologic Activity Alteration
Pain, Opioids and Pro-Inflammatory Immune Responses
Providing pain management to the patient who abuses prescription opioids presents a clinical challenge, not only due to concerns about "drug-seeking", but because they have increased sensitivity to pain, a phenomenon identified…
- Trial name
- NCT01210066
- Testing
- Fentanyl, Cold pressor test, Fentanyl plus cold pressor test
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection
Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCT
Sexually transmitted infections (STIs) caused by Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are increasing in France, with a significant proportion of asymptomatic infections.
- Conditions
- Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Sexually Transmitted Infections, Antimicrobial Resistance / Antibiotic Overuse
- Trial name
- OPTIMISE (NCT07884656)
- Testing
- cobas® Liat® CT/NG Point-of-Care Test
- Where
- 2 sites in France
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pregnancy, Cesarean Section
Shared Decision Making for Prescription Opioids After Cesarean Delivery
The specific aim of this study is to use a shared decision making tool to allow women who have undergone cesarean delivery (CD) to choose the amount of oxycodone the participants will be prescribed at discharge, within a range…
- Conditions
- Pregnancy, Cesarean Section, Prescriptions, Analgesics, Opioid
- Trial name
- NCT02770612
- Testing
- Prescribed opioids
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Quality of Life
RHWP Prescription Produce Plan
The purpose of this research study is to find out if access to fresh produce along with individual goal setting and education influences vegetable consumption, self-management [self-efficacy], resilience, or quality of life.
- Trial name
- PPP (NCT04995237)
- Testing
- PPP
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Opioid Misuse
Community Pharmacists and Opioid Misuse
Opioid medication misuse and overdose have reached epidemic proportions in the US. Community pharmacy is a potentially valuable resource for addressing opioid medication misuse.
- Trial name
- NCT03149718
- Testing
- Brief Intervention Medication Therapy Management, Standard Medication Counseling (SMC)
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Utah
Inappropriate Prescribing, Implementation Science
De-implementation of Low-value Pharmacological Prescriptions
The De-imFAR study is a two phase study that aims to carry out and test a structured, evidence-based and theory informed process involving the main stakeholders (managers, professionals, patients and researches) for the design…
- Conditions
- Inappropriate Prescribing, Implementation Science, Behavioral Sciences
- Trial name
- De-imFAR (NCT04022850)
- Testing
- A non-reflective decision assistance strategy, A both reflective and non-reflective decision information strategy, A reflective decision structure strategy
- Where
- Spain
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Substance Use Disorder (SUD), Drug Overdose
Justice Community Overdose Innovation Network II TCU Hub
The current study proposes to use a Hybrid Type 3 implementation research strategy to: 1) Significantly enhance our understanding of public health outcomes [e.g., overdose incidents and substance-use (SU)-related Emergency…
- Conditions
- Substance Use Disorder (SUD), Drug Overdose, Criminal Behavior
- Trial name
- JCOIN II TCU (NCT07528846)
- Testing
- Core-interagency community engagement approach, Enhanced-Core plus community engagement specialist
- Where
- United States
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Opioid Related Disorders
Computer-based Prescription Opioid Abuse Prevention for Adolescents
The investigators are developing an interactive, web-based program for youth ages 12-17 focused on the prevention of prescription opioid abuse because to the investigators knowledge, no science-based, interactive program focused…
- Trial name
- NCT02737696
- Testing
- Web-based prescription opioid prevention for adolescents, JustThinkTwice.gov website (DEA)
- Where
- United States
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Smoking, Alcohol Drinking
Tailored Inhibitory Control Training to Reverse EA-linked Deficits in Mid-life
Insufficient inhibitory control is one pathway through which early adversity is related to a range of problems including excessive alcohol use, tobacco use, and unhealthy eating.
- Conditions
- Smoking, Alcohol Drinking, Prescription Drug Abuse, Substance-Related Disorders
- Trial name
- REV (NCT02945371)
- Testing
- Person-centered inhibitory control training, Active behavioral response training
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Programming Languages, Patients
DESIGNING A PROGRAMMING LANGUAGE FOR PATIENT-ORIENTED PRESCRIPTIONS (POP-PL)
The purpose of this study is to create a human-readable and executable computer language to implement medical prescriptions and to evaluate and refine this language, with the goal of improving safety and efficacy of patient care
- Trial name
- NCT03837418
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Substance Use Disorders, Overdose
Emergency Medicine Peer Outreach Worker Engagement for Recovery
This is an observational, prospective case-control study evaluating the effects of an emergency department community health worker-peer recovery specialist program (PCHW), the Substance Misuse Assistance Response Team (SMART).
- Conditions
- Substance Use Disorders, Overdose, Opioid Use Disorder, Alcohol Use Disorder
- Trial name
- EMPOWER (NCT06320015)
- Testing
- Substance Misuse Assistance Response Team (SMART), Usual Care Group
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles