Clinical trials: Prescriptions
Opioid Overdose
Preventing Opioid Overdose Mortality in the United States
This study aims to conduct a randomized controlled trial of 105 syringe services programs (SSPs) throughout the United States to understand the effectiveness of a multifaceted, facilitation-based strategy at advancing naloxone…
- Trial name
- NCT03924505
- Testing
- Organize and Mobilize for Implementation Effectiveness, Dissemination
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- RTI International
Exercise Therapy, Behavior and Behavior Mechanisms
Health-Enhancing Adapted Physical Activity Program at "Mon Stade"
Introduction: Regular practice of exercise or physical activity (PA) is a recognized intervention as a determinant of good health acquisition, maintenance, or recovery for a large number of chronic pathologies.
- Conditions
- Exercise Therapy, Behavior and Behavior Mechanisms, Adherence, Patient, Lifestyle, Sedentary
- Trial name
- SESAME (NCT04716322)
- Testing
- Adapted Physical Activity
- Where
- France
- Volunteers
- 2,024 people, healthy volunteers welcome
- Sponsor
- Mon Stade Sports Medicine Centre
Medication Errors
Evaluation of an Outpatient Modified Prescription Form
The purpose of this study is to determine if a modified paper prescribing form decreases prescribing errors compared to a traditional or standard paper prescribing form.
- Trial name
- NCT00256594
- Testing
- prescription form
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Vermont
HIV Infections, HCV
A Setting Focus Overdose Prevention Intervention
A pilot injection-setting targeted peer-driven intervention to reduce HIV and hepatitis C virus transmission and overdose risk behaviors among people who inject drugs (PWID).
- Conditions
- HIV Infections, HCV, Drug Overdose
- Trial name
- Oasis (NCT05320835)
- Testing
- HIV, HCV and overdose prevention
- Where
- United States
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Drug Overdose, Drug Overdose Accidental
Behavioral Safety and Fentanyl Education: BSAFE
BSAFE is a randomized trial of a repeated-dose brief intervention to reduce overdose and risk behaviors among people who use stimulants who may have unintentional fentanyl use (UFU).
- Trial name
- BSAFE (NCT07219082)
- Testing
- BSAFE Intervention, Attention control
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- San Francisco Department of Public Health
Inappropriate Prescribing, Implementation Science
Reduction of Low-value Prescribing Through Audit and Feedback
The objective is to estimate the effect attributable to a primary care pharmacist-led audit and feedback (AF) strategy compared to the currently used AF strategy as a management tool to evaluate healthcare performance focusing on…
- Conditions
- Inappropriate Prescribing, Implementation Science, Behavioral Sciences
- Trial name
- AFFAP (NCT07336550)
- Testing
- Usual AF, Facilitated AF
- Where
- Spain
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Food Insecurity
Reducing Food Insecurity During COVID-19
This study aims to compare the effectiveness of two interventions to address food insecurity among low-income families with young children during the COVID pandemic.
- Trial name
- NCT04652596
- Testing
- Produce prescription program, Grocery store gift cards
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Substance Use Disorder
The Tobacco, Alcohol, Prescription Medication and Other Substances Tool
The purpose of the study is to develop and validate a questionnaire to screen and assess adult primary care patients for tobacco, alcohol, prescription drug, and drug use and problems related to their use.
- Trial name
- CTN0059 (NCT02110693)
- Testing
- Interviewer and tablet administration of the TAPS Tool
- Where
- 4 sites in United States
- Volunteers
- 2,057 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Infections
Improving Post-discharge Antimicrobial Use
One in five hospitalized patients is prescribed an antimicrobial at the time of discharge, and a large proportion of these post-discharge antimicrobials are unnecessary.
- Trial name
- NCT05471726
- Testing
- Prospective audit-and-feedback
- Where
- 5 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Obesity
The Leisure-time Activity and Nutrition Program
The purpose of this investigation is to conduct an 8-week pilot study to examine the effects of two different leisure-time activity prescriptions on dietary intake, leisure-time activities, and weight loss in 30 adults receiving…
- Trial name
- LEAN (NCT01142206)
- Testing
- Dietary, Physical Activity, TV Watching + Physical Activity
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Sleep, Mental Health Wellness
Prescribing Laughter for Sleep and Wellbeing in UAE University Students
This study is in line with the UAEs national drive to promote happiness and wellbeing. University students risk impaired psychological health, wellbeing, and sleep due to academic pressures.
- Trial name
- NCT04171245
- Testing
- Laughie laughter prescription, Sleep tracking equipment
- Where
- United Arab Emirates
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zayed University
Drug Overdose, Overdose of Beta-adrenergic Blocking Drug
Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition
This trial investigates effects of a glucagon bolus injection on heart rate, blood pressure and cardiac output during beta-blocker-induced cardiodepression.
- Trial name
- GLUCAGON (NCT03533179)
- Testing
- Glucagon, Esmolol, Physiologic saline - glucagon dummy
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Opioid Abuse, Prescription Drug Abuse (Not Dependent)
Validation of a Community Pharmacy-Based Prescription Drug Monitoring Program Risk Screening Tool
The goal of the study is to validate a Prescription Drug Monitoring Program-based opioid risk metric to discriminate between low, moderate, and high-risk opioid use disorder.
- Trial name
- PHARMSCREEN (NCT03936985)
- Where
- 2 sites in United States
- Volunteers
- 1,464 people, healthy volunteers welcome
- Sponsor
- University of Utah
Overdose
Permanent Supportive Housing Overdose Prevention
Permanent supportive housing (PSH), the gold standard intervention for ending chronic homelessness, has expanded rapidly across the U.S. in recent years.
- Trial name
- POP (NCT05786222)
- Testing
- CSH-Delivered Overdose Prevention Support
- Where
- United States
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Potentially Inappropriate Prescribing (PIP)
The PIP-STOPP Study
The overall objective of the present study will be to describe the occurrence of Potentially Inappropriate Prescribing (PIP) in Ontario's elderly (>65 yrs) population, assess the health and economic burden associated with it, and…
- Trial name
- PIP-STOPP (NCT02555891)
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- Bruyère Health Research Institute.
HIV (Human Immunodeficiency Virus)
Multimorbidity and Polypharmacy in People With HIV vs. the General Population in the Basque Country
People living with HIV now have a life expectancy similar to that of the general population, thanks to major advances in antiretroviral treatment.
- Trial name
- NCT07621224
- Testing
- No intervention
- Volunteers
- 12,546 people, healthy volunteers welcome
- Sponsor
- Biogipuzkoa Health Research Institute
Chronic Migraine
Gene Expression of Endocannabinoid System in Episodic and Chronic Migraine Patients
Preclinical and clinical evidence suggests a role for the dysregulation of endocannabinoid system (ES) in migraine pain, particularly in subjects with chronic migraine.
- Trial name
- NCT04324710
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Acute Respiratory Tract Infections
Optimisation of Antibiotic Prescription in Acute Noncomplicated Respiratory Tract Infections in Children (OptimAP Study)
Background: High-volume antibiotic prescribing in primary care is a major driver of antibiotic resistance. Education of physicians and patients can lower prescribing levels, but it frequently relies on highly trained staff.
- Trial name
- OptimAP (NCT05166369)
- Testing
- Communication skills training, Mobile phone application on RTI
- Where
- 4 sites in Spain
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Type 2 Diabetes, Food Insecurity
The Food for Health Study
The project, called Food for Health (F4H), will study a new Produce Prescription Program (PPP) designed for rural Native American older adults.
- Conditions
- Type 2 Diabetes, Food Insecurity, Rural Health
- Trial name
- F4H (NCT07254689)
- Testing
- Produce Prescription Program
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Montana
Erectile Dysfunction
Actual Use Trial of Tadalafil 5 mg
The purpose of this actual use trial (AUT) is to evaluate if participants can appropriately select and use the study product [Cialis over the counter (OTC)] using the labeling and the mandatory health survey assessment (HSA) for…
- Trial name
- NCT06805513
- Testing
- Tadalafil 5 mg tablets with a digital tool.
- Where
- United States
- Volunteers
- 2,212 people, healthy volunteers welcome
- Sponsor
- Sanofi