Clinical trials: Pressure Injury Prevention
Pressure Ulcer, Pressure Injury
Pressure Ulcer Incidence Cat. II+ on a Static Air Mattress: a Multicenter Cohort Study in Nursing Home Residents at Risk
Pressure Ulcers are a serious and common problem for residents admitted to long-term care facilities and community care patients.
- Conditions
- Pressure Ulcer, Pressure Injury, Pressure Sore, Bed Sore
- Trial name
- NCT03725787
- Testing
- CuroCell S.A.M. ® pro mattress
- Where
- 8 sites in Belgium
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Ghent
Pressure Injury
Comparing Aloe Vera Gel and Rosemary Oil in Pressure Injury Prevention
Most patients admitted to the orthopedic ward are at risk of developing pressure ulcers. Today, the tendency to use medicinal herbs in pressure ulcer treatment has increased due to the variety of effective compounds and their…
- Trial name
- NCT05578638
- Testing
- Aloe Vera rosemary tropical application, aloevera tropical application, rosemary tropicalapplication
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Mansoura University
Diabetes Complications
Abnormal Plantar Pressure in Patients With Diabetes
The prevalence of abnormal plantar pressure distribution (APD) and its connection with various factors among patients with diabetes is not known.
- Trial name
- NCT03426566
- Testing
- retrospective observational study with no intervention
- Where
- Poland
- Volunteers
- 974 people
- Sponsor
- Wroclaw Medical University
Pressure Ulcers
Evaluate the Efficacy of a Silk-Like Fabric for the Prevention of Pressure Sores in a Long Term Care Setting
The primary purpose of this research study is to evaluate if DermaTherapy® bedding will significantly reduce pressure ulcer incidence by decreasing maceration, friction, and shearing among residents of Nursing Homes.
- Trial name
- NCT01403272
- Testing
- DermaTherapy® Linen and underpads.
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Precision Fabrics Group, Inc.
Wound Infection, Wound Complication
Randomised Control Study to Asses the Role of Negative Pressure Wound Therapy (NPWT) in the Management of Wound in Surgical Patient
Aim of the study is to assess the role of negative pressure therapy in the prevention of the complication of the laparotomy wound in the high risk patients group.
- Trial name
- NCT02331485
- Testing
- PICO + Acticoat group
- Where
- Ireland
- Volunteers
- 150 people
- Sponsor
- St James Connolly Memorial Hospital
Pressure Injury
Skin Change Actions by Nursing
Pressure injuries, local areas of damage to the skin and underlying soft tissue that are costly and painful, are often preventable with timely use of prevention strategies.
- Trial name
- SCAN (NCT06127524)
- Testing
- SEM Scanner
- Where
- 7 sites in United States
- Volunteers
- 4,733 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autonomic Dysreflexia
Botox for Neurogenic Detrusor Overactivity and the Prevention of Autonomic Dysreflexia Following SCI
The purpose of this study is to investigate the impact of 200 U intradetrusor injected OnabotulinumtoxinA (Botox®, Allergan, Inc.) (20 sites, trigone sparing) for neurogenic detrusor overactivity (NDO) and its role on reducing…
- Trial name
- NCT02298660
- Testing
- BOTOX
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Rick Hansen Institute
Infection Wound
Negative Pressure Wound Therapy for Prevention of Groin Infection Following Vascular Surgery
Surgical site infection in vascular surgery is a relatively common event with reported incidence as high as 43%. When considering the groin alone, the incidence is around 20% (30% when considering any wound complication).
- Trial name
- PICO (NCT03460262)
- Testing
- Standard cutiplast®, PICO®
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Stroke Patients
Prevention and Treatment of Reperfusion Injury After Mechanical Thrombectomy in Acute Ischemic Stroke
Ischemic stroke accounts for 80% of all strokes and there is a lack of effective treatment options.Mechanical thrombectomy can significantly improve the vascular recanalization rate and reduce the disability rate of stroke, but…
- Trial name
- NCT05282290
- Testing
- Antihypertensive drugs (no restriction on the type of drugs)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Surgical Site Infection, Groin Infections
Negative Pressure Wound Therapy for Surgical Site Infection Prevention in Common Femoral Artery Exposure
The purpose of this randomized clinical trial is to investigate the role of negative pressure wound therapy (NPWT) vs standard sterile gauze therapy on the incidence of surgical site infections (SSI) in primarily closed groin…
- Trial name
- NCT03935659
- Testing
- Negative Pressure Pressure Wound Therapy, Standard Wound Care
- Where
- United States
- Sponsor
- Henry Ford Health System
Surgical Wound Infection, Infection; Cesarean Section
Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following Caesarean Section
The purpose of this study is to examine whether obese women (BMI >= 30) who give birth by caesarean section have a reduced incidence of wound infection and dehiscence when incisional Negative Pressure Wound Therapy is applied…
- Conditions
- Surgical Wound Infection, Infection; Cesarean Section, Cesarean Section; Dehiscence, Complications; Cesarean Section
- Trial name
- NCT01890720
- Testing
- iNPWT, Standard postoperative wound dressing
- Where
- 5 sites in Denmark
- Volunteers
- 876 people
- Sponsor
- Odense University Hospital
Pressure Ulcers
Pressure Ulcer Prevention in Intensive Care Unit (ICU)
The study is designed as a randomised controlled trial of trauma patients admitted to the Royal Melbourne Hospital (RMH) Emergency Department (ED) and subsequently transferred to the Intensive Care Unit (ICU).
- Trial name
- NCT01356459
- Testing
- Mepilex Border Dressing
- Where
- Australia
- Volunteers
- 440 people
- Sponsor
- Melbourne Health
Pressure Injury, Skin Lesions
Paraffin Oil for Preventing Tourniquet-Related Skin Lesions in Upper Extremity Surgery
This randomized controlled trial aims to evaluate the effectiveness of topical paraffin oil application in preventing tourniquet-related skin lesions in patients undergoing upper extremity surgery.
- Conditions
- Pressure Injury, Skin Lesions, Skin Injury
- Trial name
- PARA-TOUR (NCT07523958)
- Testing
- Paraffin Oil
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Medipol University Hospital
Wound of Skin
Efficacy of Prophylactic Negative Pressure Wound Therapy (NPWT)
The role of prophylactic negative pressure wound therapy (NPWT) is promising in reducing wound-related complications. However, the prophylactic use of NPWT in reducing wound complications in patients who underwent conventional…
- Trial name
- EFESO (NCT05727995)
- Testing
- PICO7, usual care dressing
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Policlinico S. Donato
Spinal Cord Injury, Pressure Ulcers
Pressure Ulcer Prevention for SCI Using a Tele Home Program
NRI research focuses on nursing interventions that are patient-centered, culturally congruent, cost-effective and outcome-driven. High priority populations of interest are veterans with Spinal Cord Injuries (SCI).
- Trial name
- TELEPUPPS (NCT01166828)
- Testing
- TELLEPUPPS
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injuries, Autonomic Dysreflexia
NO AD: Use of Nitric Oxide (NO) Donors for the Prevention of Autonomic Dysreflexia (AD) During Bowel Care Following SCI
This project aims to evaluate the safety and efficacy of using a short-acting drug to reduce the maximal blood pressure during dangerous blood pressure spikes that happen during bowel care in individuals with spinal cord injury.
- Trial name
- NO AD (NCT05635851)
- Testing
- Glyceryl Trinitrate Only Product in Oromucosal Dose Form
- Volunteers
- 26 people
- Sponsor
- Simon Fraser University
Compartment Syndrome
Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg
An investigation of a new catheter and pressure monitor system that may help to prevent a complication called compartment syndrome from developing in an injured leg.
- Trial name
- TS2 (NCT00681616)
- Testing
- Compartment Monitoring System (CMS), Compartment Monitoring System with Active Fluid Removal, Compartment Monitoring System without fluid removal
- Where
- 13 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Twin Star Medical, Inc.
Infection, Drainage
Comparison of Negative Pressure Wound Therapy vs. Conventional Dressings for Prevention of Wound Complications After Revision THA
Wound complications and surgical site infections following revision total joint arthroplasty result in significant morbidity and cost.
- Trial name
- NCT03321799
- Testing
- Negative Pressure Wound Therapy (NPWT), Sterile Antimicrobial Dressings
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Skin Wound, Complication of Surgical Procedure
Pneumatic Tourniquet Application in Upper Extremity Surgeries
Purpose: This study investigated the effect of cuff pressure and the selection of protective padding material(PPM) on the prevention of skin complications associated with pneumatic tourniquet(PT) application in upper extremity…
- Trial name
- NCT06575088
- Testing
- Standard tourniquet pressure (250 mmHg), Limb occlusion pressure, Cotton Pad
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa City Hospital
Pressure Ulcer (PU)
The Effect of Pulse Oximeter Probe Replacement Interval on Pressure Injury Development in Intensive Care Patients
Patients admitted to intensive care units (ICUs) are at increased risk of medical device-related pressure injuries (MDRPIs) due to the prolonged use of monitoring devices.
- Trial name
- NCT07704710
- Testing
- Pulse Oximeter Probe Repositioning Every 2 Hours, Pulse Oximeter Probe Repositioning Every 4 Hours
- Where
- Turkey (Türkiye)
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Emine Arici Parlak