Clinical trials: Pressure Ulcers Stage II
Pressure Ulcers, Pressure Ulcers Stage III
Efficacy of a Polyhexanide Biguanide-Based Gel in the Prevention of Biofilm Formation in Pressure Ulcers
INTRODUCTION: Pressure ulcers (PU) are one of the main challenges for nursing in our country. Wound bed preparation and the TIME algorithm provide essential tools for adequately treating these lesions.
- Conditions
- Pressure Ulcers, Pressure Ulcers Stage III, Pressure Ulcer Prevention, Pressure Ulcer ( Stage 2-3)
- Trial name
- EGELPUPP (NCT07391748)
- Testing
- To determine the efficacy of a gel containing polyhexanide and biguanide, alone or in combination with alginate with or without silver, in preventing biofilm in PU, in terms of healing at 4 weeks
- Volunteers
- 140 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Pressure Ulcer Stage 1, Pressure Ulcers Stage II
Evaluating the Efficacy of a Tocotrienols-Loaded Dressing in Wound Care for Pressure Ulcers
The goal of this clinical trial is to investigate the effects of the dressing containing Tocotrienols on patients with stage 1 and stage 2 pressure ulcers.
- Conditions
- Pressure Ulcer Stage 1, Pressure Ulcers Stage II, Pressure Injuries
- Trial name
- TOCOWO (NCT07694583)
- Testing
- Tocotrienol-loaded formulated dressing, Conventional dressing
- Where
- Malaysia
- Volunteers
- 114 people
- Sponsor
- Monash University Malaysia
Pressure Sore, Pressure Ulcer
EmoLED Medical Device Treatment of Second and Third Stage Pressure Ulcers
The present clinical study aims to verify the effectiveness and safety of the blue light photobiomodulation therapy with EmoLED medical device in supporting the reparative process of the area of the second and third stage…
- Conditions
- Pressure Sore, Pressure Ulcer, Pressure Ulcers Stage III, Pressure Ulcers Stage II
- Trial name
- RISE_UP (NCT05130814)
- Testing
- blue light photobiomodulation, cleansing, hyaluronic acid gauze plus polyurethane foam
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Emoled
Chronic Pressure Ulcers
PuraPly® AM Plus the Standard of Care to Standard of Care Alone for the Management of Stage II-IV Pressure Ulcers.
This is a prospective, multi-center, randomized, controlled clinical study Of PuraPly® AM and standard of care (SOC) compared to SOC alone for the management of Stage II-IV pressure ulcers located in the gluteal, ischial, hip…
- Trial name
- NCT03502824
- Testing
- PuraPly® Antimicrobial Wound Matrix, SOC for Pressure Ulcers
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Organogenesis
Eustachian Tube Dysfunction, Middle Ear Barotrauma
Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury
- Trial name
- NCT04776967
- Testing
- Hyperbaric Compression Profile
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwell Health
Pressure Ulcers
Evaluate the Efficacy of a Silk-Like Fabric for the Prevention of Pressure Sores in a Long Term Care Setting
The primary purpose of this research study is to evaluate if DermaTherapy® bedding will significantly reduce pressure ulcer incidence by decreasing maceration, friction, and shearing among residents of Nursing Homes.
- Trial name
- NCT01403272
- Testing
- DermaTherapy® Linen and underpads.
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Precision Fabrics Group, Inc.
Pressure Ulcers Stage II, Pressure Ulcers Stage III
Safety Evaluation of the KLOX BioPhotonic System in Stage II and III Pressure Ulcers
The primary objective of these case series is to evaluate the safety and tolerability of the KLOX BioPhotonic System as adjunctive therapy to Standard Of Care (SOC) in patients with stage II or III pressure ulcers.
- Trial name
- NCT02222454
- Testing
- KLOX BioPhotonic System
- Where
- 4 sites in Canada
- Volunteers
- 3 people
- Sponsor
- KLOX Technologies Inc.
Pressure Injury Stage 2
Open-label Study to Evaluate the Efficacy and Safety of Fespixon Cream for the Treatment of Pressure Injury in Sacrum and Greater Trochanter Wound
Open-label Study to Evaluate the Efficacy and Safety of Fespixon Cream for the Treatment of Pressure Injury in Sacrum and Greater Trochanter Wound
- Trial name
- NCT05317442
- Testing
- Fespixon Cream
- Where
- 3 sites in Taiwan
- Volunteers
- 10 people
- Sponsor
- Taipei Medical University WanFang Hospital
Spinal Cord Injuries, Paraplegia
Interactive Telehealth for Wheelchair Users
During typical daily activity, people with established spinal cord injury perform significantly fewer pressure-relief maneuvers than the recommended frequency while overestimating their adherence on recall surveys of pressure…
- Conditions
- Spinal Cord Injuries, Paraplegia, Pressure Ulcer, Buttock
- Trial name
- NCT04266808
- Testing
- An interactive telehealth monitoring and biofeedback system, Education Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rancho Research Institute, Inc.
Pressure Injury
Validation and Usability Study of Intermittent Electrical Simulation in Management of Pressure Injuries Stages 1 and 2
The focus of this study will be early stage pressure ulcers, which can quickly progress to stage 3, 4 or deep tissue injury The proposed study explores the feasibility of intermittent electrical stimulation (IES),Prelivia, a…
- Trial name
- IESPI (NCT06435143)
- Testing
- Prelivia
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Stage 1 Pressure Ulcer, Stage 2 Pressure Ulcer
The PROTECT 2 Study : Pressure Injury Treatment by Intermittent Electrical Stimulation: A Randomized, Controlled Trial
Multicentered randomized controlled study with adaptive design to evaluate if Intermittent Electrical Stimulation (IES) decreases progression and facilitates healing of pressure injuries for patients with, sacral / ischial…
- Trial name
- NCT05085288
- Testing
- Intermittent electrical stimulation system (IES) treatment and turning patient every two hours, Turning population every two hours
- Where
- 3 sites in United States, Austria
- Volunteers
- 1,100 people
- Sponsor
- The Cleveland Clinic
Pressure Ulcers Stage II, Pressure Ulcers Stage III
Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries
Pressure injuries, commonly known as pressure ulcers, affect over 2.5 million people in the United States. Pressure injuries are classified into four escalating stages, from intact skin to full thickness wounds with deep tissue…
- Conditions
- Pressure Ulcers Stage II, Pressure Ulcers Stage III, Pressure Ulcer, Stage IV
- Trial name
- NCT05496296
- Testing
- Altrazeal® Transforming Powder Dressing
- Where
- 14 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- ULURU Inc.
Pressure Ulcers, Spinal Cord Injury
Comparison of HP011-101 to Standard Care for Stage I-II Pressure Ulcers in Subjects With Spinal Cord Injury
The trial will compare the effects of 14 days treatment with HP011 101 versus Standard Care in subjects with Stage I or II pressure ulcers as a complication of spinal cord injury, measured as change from baseline in composite…
- Trial name
- NCT01433159
- Testing
- HP011-101 (Xenaderm Ointment), Standard Care
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Healthpoint
Pressure Ulcer
AutoloGel Therapy to Usual and Customary Care in Pressure Ulcers
The aim of this trial is to demonstrate the effectiveness of complete wound healing in a prospective, open-label, case-matched cohort-controlled trial in which pressure ulcers will be treated using AutoloGel and standard care and…
- Trial name
- NCT01819142
- Testing
- AutoloGel
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Cytomedix
Pressure Injury, Venous Leg Ulcer
Pivotal Study of an Antimicrobial Wound Dressing to Treat Chronic Wounds
The goal of this clinical trial is to assess the impact that the NanoSALV wound dressing can have on managing severe chronic wounds and feasibility for patients, providers, and health systems in different health care settings…
- Conditions
- Pressure Injury, Venous Leg Ulcer, Pressure Injury Stage 2, Pressure Injury Stage III
- Trial name
- NCT05619237
- Testing
- NanoSALV Catalytic
- Where
- 4 sites in Canada
- Volunteers
- 44 people
- Sponsor
- Chester Ho, MD
Pressure Ulcers
HP011-101, HP828-101, and Standard Care for Pressure Ulcers
Testing a drug and a device for the treatment of pressure ulcers, compared with current treatments.
- Trial name
- NCT01273428
- Testing
- HP011-101, HP-828-101, Standard Care
- Sponsor
- Healthpoint
PARAPLEGIA
Pressure Ulcer Formation Prevention in Paraplegics Using Computer and Sensory Substitution Via the Tongue.
Will the use of sensory substitution by lingual electric stimulation improve in a suitable way, for paraplegic subject, the spatial distribution of pressure applied at the seat/skin interface in order to prevent the formation of…
- Trial name
- NCT00429013
- Testing
- Tongue Display Unit
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Grenoble
Pressure Ulcer
Envision® Surface Evaluation
This observational study will acquire initial clinical practice utilization and product safety data for the Envision® surface.
- Trial name
- NCT00405795
- Testing
- Envision® Patient Support System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hill-Rom
Pressure Injury, Pressure Injury Stage 2
Zinc Oxide VS MEBO
randomize control trial to evaluate the efficacy of using zinc oxide versus moist exposed wound ointment in treatment of second stage pressure ulcer.
- Conditions
- Pressure Injury, Pressure Injury Stage 2, Bedsore, Pressure Ulcers Stage II
- Trial name
- NCT07193849
- Testing
- MEBO Wound Ointment, zinc oxide
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 76 people
- Sponsor
- King Abdullah Medical City
Pressure Ulcer, Stage IV, Osteomyelitis
A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.
The purpose of this trial is to assess the safety, tolerability and between-group effect size of STIMULAN VG (with debridement) and a course of systemic antibiotics to standard of care (debridement and systemic antibiotics only)…
- Trial name
- BLADE OPU2 (NCT06283979)
- Testing
- STIMULAN VG, Standard of Care
- Where
- 9 sites in United States
- Volunteers
- 60 people
- Sponsor
- Biocomposites Ltd