Clinical trials: Pressure Wound
High-risk Pregnancy
Leg Heating in Pregnant Women With Obesity
Obesity is a major risk factor for hypertensive disorders of pregnancy (HDP). The underlying mechanisms are largely unclear, but maternal vascular endothelial dysfunction is likely involved.
- Trial name
- NCT06932250
- Testing
- Leg heating
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pressure Injuries, Pressure Injury
Using Music During Wound Care Among Seniors With Pressure Injuries
Pressure injuries (also known as pressure wounds or bed sores) are increasingly common among older adults living in care homes. These wounds often require regular dressing changes, which can be uncomfortable for some.
- Conditions
- Pressure Injuries, Pressure Injury, Pressure Ulcer (PU)
- Trial name
- NCT07456618
- Testing
- Music listening
- Where
- 11 sites in Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Acute Brain Injury, Traumatic Brain Injury
Effect of Central Venous Catheterization on Brain Pressure in Acute Brain Injury Patients
Acute brain injury (ABI) is a serious condition that can cause a dangerous increase in pressure inside the skull (called intracranial pressure, or ICP), which can harm the brain.
- Conditions
- Acute Brain Injury, Traumatic Brain Injury, Intracerebral Hemorrhage, Aneurysmal Subarachnoid Hemorrhage (aSAH)
- Trial name
- CVC-ICP (NCT07704528)
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Beijing Tiantan Hospital
Obesity, Surgical Site Infections
Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery
The investigators aim to show that single use negative pressure dressings can decrease the rate of wound complications in obese women (BMI > 40 kg/m2) undergoing cesarean delivery at a tertiary medical center by randomizing women…
- Conditions
- Obesity, Surgical Site Infections, Wound Complications, Complications; Cesarean Section
- Trial name
- NCT02799667
- Testing
- Standard Dressing, Negative Pressure Wound Therapy Dressing
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Spinal Cord Injury
Bowel Care and Cardiovascular Function After Spinal Cord Injury
The main goal of this project is to determine the effects of lidocaine lubricant on cardiovascular function during routine bowel care in individuals with spinal cord injury.
- Trial name
- NCT01567605
- Testing
- Lidocaine lubricant
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- Simon Fraser University
Diabetic Foot Ulcer
Evaluation of Combinational Use of Negative Pressure Wound Therapy (NPWT) for Diabetic Foot Wounds
Singapore has one of the world's highest diabetes-related lower limb amputation rates in the world. Between 2008 - 2017, 4724/5306 (89.0%) of all major amputations and 6656/7227 (92.1%) of all toe/ray amputations performed in…
- Trial name
- NCT06832787
- Testing
- Negative Pressure Wound Therapy, Kerecis, Delayed primary closure with local flap
- Where
- 2 sites in Singapore
- Volunteers
- 75 people
- Sponsor
- Singapore General Hospital
Pressure Ulcers
Wound Management for Sacral Pressure Ulcers With Necrotic Tissue
Evaluation of a wound care debridement product and a moisturizer on sacral pressure ulcer wounds
- Trial name
- NCT02224638
- Testing
- TheraHoney HD, SkinTegrity
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Medline Industries
Negative-Pressure Wound Therapy, Wound Heal
Compare Stoma Reversal Wound Outcomes Between NPWT and Secondary Intention Healing
This was a single-center, parallel-group randomized controlled trial conducted in 2025 at the General Surgery Ward of the Sindh Institute of Urology and Transplantation (SIUT), Karachi.
- Conditions
- Negative-Pressure Wound Therapy, Wound Heal, Stoma Site Infection, Surgical Site Infection
- Trial name
- NCT07258134
- Testing
- Negative Pressure Wound Therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Maryam Arbab
Pressure Ulcer
The Effect of Prolotherapy in the Care Process of Pressure Injuries
The goal of this [type of study: randomized controlled clinical trial] is to [Determining the effect of prolotherapy use on the wound care process].
- Trial name
- NCT05874284
- Testing
- Gelofusin
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Fenerbahce University
Pressure Ulcer, Pressure Injury
Efficacy of the Dabir Surfaces Micropressure Overlay for Decubitus Ulcer Prevention During Cardiac Surgery
This is a systematic random sampling study of the effects of the Dabir Micropressure Overlay on perioperative pressure injuries during cardiac surgery.
- Trial name
- NCT03884634
- Testing
- Dabir Micropressure Overlay
- Where
- United States
- Volunteers
- 6,627 people
- Sponsor
- The Cleveland Clinic
Urinary Bladder, Neurogenic, Blood Pressure
Recovery of Bladder and Sexual Function After Human Spinal Cord Injury
This study will incorporate critical cross viscero-visceral intersystem interactions to 1) investigate in a controlled laboratory setting and then with mobile at-home monitoring the extent, severity, and frequency of occurrence…
- Conditions
- Urinary Bladder, Neurogenic, Blood Pressure, Autonomic Dysreflexia, Bowel Incontinence
- Trial name
- NCT04193709
- Testing
- Spinal Cord Epidural Stimulation
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Louisville
Block
Interfascial Pressure Into Ultrasound Guided Anterior Quadratus Lumborum Block Application
The block has been shown to be the result of abdominal analgesia as a result of application between the quadratus lumborum (QL) muscle and the leaves in the thoracolumbar fascia.
- Trial name
- NCT04094987
- Testing
- inter-fascial pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Traumatic Brain Injury, Middle Cerebral Artery Stroke
Intracranial Pressure After Decompressive Craniectomy
Observational study to investigate the natural course of intracranial pressure (ICP) after decompressive craniectomy (DC) using long-term telemetric ICP monitoring.
- Conditions
- Traumatic Brain Injury, Middle Cerebral Artery Stroke, Intracranial Hemorrhages, Intracranial Hypertension
- Trial name
- NCT03364634
- Testing
- Intracranial pressure monitoring
- Volunteers
- 17 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spinal Cord Injury
Autonomic Effects of Stimulation in SCI
This study aims to determine the effects of transcutaneous spinal cord stimulation to increase blood pressure and use that device to increase power output and heart rate recovery during arm cycle ergometry.
- Trial name
- NCT05664646
- Testing
- Transcutaneous Spinal Cord Stimulation (TSCS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Respiratory Failure
Regional Distribution Differences Between Neurally Adjusted Ventilatory Assist and Pressure Support Ventilation
Neurally adjusted ventilatory assist (NAVA) is an FDA approved mode of mechanical ventilation. This mode of ventilation is currently in routine use in adult, pediatric and neonatal intensive care units.
- Trial name
- NCT01504373
- Testing
- Neurally Adjusted Ventilatory Assist (NAVA)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Children's Hospital
Leg Ulcer, Diabetic Foot Ulcer
Study to Examine Clinical Performance and Safety of Cutimed® Gelling Fiber in Routine Clinical Practice
This is a post - market study with a wound dressing, a CE-marked medical device available on the european market. The device will be used in routine clinical practice, i.e.
- Conditions
- Leg Ulcer, Diabetic Foot Ulcer, Pressure Ulcer, Surgical Wound
- Trial name
- GELFI (NCT05148390)
- Testing
- Cutimed® Gelling Fiber
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- BSN Medical GmbH
Pain, Acute
Ethyl Chloride for NPWT
Negative pressure wound therapy (NPWT) has been shown to improve wound care outcomes for acute and chronic wounds as well as for surgical incision sites.
- Trial name
- NCT04635696
- Testing
- Ethyl chloride, Tissue culture grade water
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- ProMedica Health System
Weaning Failure
Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients With Traumatic Brain Injury
The aim of this study will be to measure the predictive power of the respiratory muscle determinants including The maximal inspiratory pressure, and central drive determinant including Airway occlusion pressure and ratio between…
- Trial name
- NCT06627686
- Testing
- Air way occlusion pressure
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Diabetic Foot Ulcer, Venous Leg Ulcer
DETEC® Esterase for Screening Wound Infection at Point of Care
This non-interventional, single-blinded, prospective, observational study assesses the planar distribution of leukocyte esterase in wounds by placing wound exudates soaked wound dressings in the DETEC® Esterase device during…
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer
- Trial name
- NCT04614870
- Testing
- DETEC® Esterase
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Progenitec Inc.
Head Injury Trauma
Intracranial Pressure Monitoring in Sever Traumatic Brain Injury Single Center Experience
Intracranial pressure (ICP) is defined as the pressure inside the skull, and therefore, the pressure inside the brain tissue and the cerebrospinal fluid (CSF).
- Trial name
- NCT03721003
- Testing
- ICP monitoring
- Volunteers
- 32 people
- Sponsor
- Assiut University