Clinical trials: Preterm Babies
Hypothermia
mOm Incubator Pilot Study
The mOm Incubator is a collapsible infant incubator designed to provide a level of thermoregulation that meets the standards set for conventional incubators whilst being low cost and space-saving.
- Trial name
- NCT03450668
- Testing
- mOm incubator, standard incubator
- Where
- United Kingdom
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- mOm incubators
Premature Birth, Obstructive Lung Disease
Pulmonary Outcomes of Bronchopulmonary Dysplasia in Young Adulthood
Preterm birth alters the normal sequence of lung development with lasting respiratory consequences. It is still unclear whether observed respiratory morbidities in preterm born individuals reflect sequelae from a non-progressive…
- Conditions
- Premature Birth, Obstructive Lung Disease, Bronchopulmonary Dysplasia
- Trial name
- NCT02820818
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Premature Births
Long-term Effect of The Mother Infant Transaction Program (MITP)
The purpose of this study is to investigate if a cost and time effective intervention in a previous RCT for preterm infants and their parents can reduce the parents experience of concern and stress, and improve the childrens…
- Trial name
- 2007/2/0150 (NCT00903149)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Cognitive Developmental Delay
Neurocognitive Follow-Up (FU) Study
This is a follow-up study of a recently completed trial (17.14.INF) evaluating the growth of pre-term infants. Enrolled children will undergo neurocognitive assessments at 18- and 24-months of corrected age (CA).
- Trial name
- NCT04962035
- Testing
- Neurocognitive Follow-up
- Where
- 3 sites in Poland, Slovakia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Perinatal Death, Respiratory Distress Syndrome, Newborn
Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities
Hyperoxygenation for resuscitation of abnormal fetal heart rate tracings has been routine obstetric practice. However, there have not been any studies to support this practice.
- Conditions
- Perinatal Death, Respiratory Distress Syndrome, Newborn, Hypoxic-Ischemic Encephalopathy, Neonatal Seizure
- Trial name
- NCT03996317
- Testing
- Room air
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Puerperium, EFTs
Fatigue, Anxiety, and Mother-Baby Bonding and Emotional Freedom Technique
Fatigue, Anxiety, and Mother-Baby Bonding and Emotional Freedom Technique
- Trial name
- EFT (NCT06997211)
- Testing
- EFT
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Preterm Birth, Parent-Child Relations
Skin-to-skin Contact in Neonatal Intensive Care Unit (NICU), Caregiving Touch and Neural Correlates of Slow Stroking Touch in Preterm Infants
Preterm (PT) infants spend their first weeks of life in Neonatal Intensive Care Unit (NICU) where receive little affective physical contact, which plays a crucial role in brain development.
- Trial name
- NCT04293939
- Testing
- Functional Magnetic Risonance Imaging (fMRI) acquisition
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Preterm, Sensory Disorder
Mother-to-infant Bonding and Prematurity Are Associated With Sensory Processing at 12 Months of Age
Establishing a strong bond between mother and infant is crucial for fostering healthy relationships in the future. This research sought to investigate the correlation between mother-to-infant bonding and sensory processing, as…
- Conditions
- Preterm, Sensory Disorder, Attachment Disorder
- Trial name
- NCT06232811
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gazi University
Premature, Necrotizing Enterocolitis
Intestinal Perfusion After Feeding in Preterm and Term Infants
This is a pilot exploratory observational prospective cohort phase I study. In this study, we will gather preliminary data to evaluate (i) the magnitude of changes in blood flow in the bowel before and after feeding and (ii) the…
- Trial name
- NCT06319326
- Testing
- Evaluation of intestinal perfusion with color Doppler abdominal ultrasound before and after feeding.
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Pain
The Holding Study: Feeding Analgesia in Preterm Infants
The purpose of this study is to compare the effects of mothers' skin-to-skin holding during feeding via a soother trainer with the effects of pacifier sucking on preterm infant biobehavioural responses during and immediately…
- Trial name
- NCT00414258
- Testing
- breastfeeding
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Necrotizing Enterocolitis of Newborn
The Intestinal Dysbacteriosis in the Pathogenesis of Necrotizing Enterocolitis
Study Description The goal of this observational study is to detect intestinal flora and the metabolic products in premature infants diagnosed as necrotizing enterocolitis. The main questions it aims to answer are: 1.
- Trial name
- NCT05619055
- Testing
- Routine treatment
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zuohui Zhao
Infant, Premature, Diseases, Congenital Abnormalities
Esophageal Motility and Airway Defenses Among Infants
Feeding difficulties and airway related consequences contribute significantly to the infant mortality and morbidity. Some of these problems may be dependent on neural control and muscular function.
- Conditions
- Infant, Premature, Diseases, Congenital Abnormalities, Perinatal Asphyxia
- Trial name
- NCT00062452
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy
An Observational Study to Assess Respiratory Syncytial Virus (RSV) Respiratory Events Among Premature Infants
The primary objective is to assess the burden of respiratory disease in outpatient settings among 32 to 35 weeks' gestational age (wGA) infants in the USA who did not receive RSV prophylaxis during the infants' first RSV season.
- Trial name
- NCT00983606
- Where
- 222 sites in United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Premature Birth
Early Behavioral Intervention for Preterm Infants
The purpose of this study is to determine the effects of Family Nurture Intervention in preschool aged children between 2.5 and 4.5 years of age who were born prematurely and exhibit developmental deficits.
- Trial name
- EBI (NCT02379130)
- Testing
- Family Nurture Intervention, Play and Nutrition Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Columbia University
Nursing Care
Thermoregulation in the Preterm Infant
The purpose of this study is to compare the response of temperature adaptation in preterm infant using the polyethylene wrap with and without previous drying.
- Trial name
- NCT01236599
- Testing
- Polyethylene for thermoregulation in the preterm infant
- Where
- Mexico
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Premature Birth
Group Antenatal Care: Effectiveness and Contextual Factors Linked to Implementation Success in Malawi
In this study, we test the effectiveness of an evidence-based model of group antenatal care by comparing it to individual (usual) antenatal care (Aim 1) across 7 antenatal clinics in Blantyre District, Malawi.
- Trial name
- NCT03673709
- Testing
- Antenatal Care
- Where
- 7 sites in Malawi
- Volunteers
- 1,887 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Premature Infant Disease, Newborn Morbidity
Effects of Confortable Environment, Kangaroo Care and Music Therapy in Newborns in Neonatal Intensive Care Unit
Creating a comfortable environment, implementing kangaroo care, and incorporating music therapy are crucial interventions for newborns hospitalized in the Neonatal Intensive Care Unit (NICU).
- Trial name
- PRE-CARE (NCT06256406)
- Testing
- in the field of rehabilitation and neonatal care: the combination of Kangaroo care method and music therapy
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Policlinico Universitario, Catania
Infant, Premature
The Effect of Replacement Frequency of Electrodes on Skin in Infant
In the Pediatric Intensive Care Unit (PICU), each child and infant is monitored to determine the status of the underlying disease by constantly monitoring the main variables, to help diagnosis and to guide treatment.
- Trial name
- NCT05016167
- Testing
- Replacement every 24 hours, Replacement every 12 hours
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Infant, Premature, Diseases
A Single Blinded Study on the Effect of Saccharomyces Boulardii CNCM I-745 on Growth and Development in Preterm Infants
Immature gastrointestinal functions increase the risk of poor growth as well as nosocomial infections and necrotizing enterocolitis (NEC) in the preterm infant.
- Trial name
- SBP (NCT02310425)
- Testing
- S. boulardii
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Lingfen Xu, MD
Bacteremia, Infant, Very Low Birth Weight
Preventing Catheter-related Bacteremia When Administering Injectable Medications in Premature Infants.
This study evaluates the potential interest of a new multi-lumen infusion access device (Edelvaiss® Multiline NEO) in the prevention of catheter-related bacteremia when administering injectable drugs in premature infants.
- Trial name
- MultilineNEO (NCT02633124)
- Testing
- Edelvaiss Multiline NEO, Standard Infusion Set
- Where
- 4 sites in France
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille