Clinical trials: Preterm Birth
Preterm Birth, Health Care Utilization
Health and Wellness After Preterm Birth
This study continues an adaptation of the behavioral intervention Care Coordination After Preterm Birth (CCAPB). This is a pragmatic pilot randomized controlled feasibility trial of CCAPB with baseline and post-intervention…
- Conditions
- Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage
- Trial name
- NCT05756634
- Testing
- Care Coordination after Preterm Birth (CCAPB)
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Preterm Birth
Mobile Strategy to Reduce the Risk of Recurrent Preterm Birth
Preterm births are defined as delivery prior to 37 weeks gestation and account for 35% of infant deaths in the first year of life.
- Trial name
- NCT04663607
- Testing
- Use of PretermConnect App
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Stanford University
Temperature, Preterm
Body Temperature in Preterm Neonates: Creating a Data Model
The aim of this study is to examine the relationship between the characteristics, medical history, interventions performed within the first six hours, and follow-up findings of preterm newborns receiving respiratory support and…
- Trial name
- NCT07176364
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Preterm
The Effect of Parental Participation on Newborn Comfort During Diaper Care
It was aimed to determine the effect of parental participation on newborn comfort during diaper care practice in preterm infants.
- Trial name
- NCT06345742
- Testing
- No parental participation, Mother participation, Father participation
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Pregnancy, Pregnancy Complications
AI-POCUS for Maternal and Neonatal Health in Ethiopia
Maternal and neonatal health remains one of the most pressing global health challenges, particularly in low- and middle-income countries (LMICs).
- Conditions
- Pregnancy, Pregnancy Complications, Preterm Birth, Fetal Growth Restriction
- Trial name
- AIM-ETH (NCT07171086)
- Testing
- AI-POCUS (BabyChecker, Delft Imaging), AI-POCUS (Edan, China)
- Where
- Ethiopia
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn
Amniotic Fluid & the Preterm Gut
Background: Necrotizing enterocolitis (NEC) and sepsis in preterm infants have been linked to intestinal immaturity and preclinical gut microbiota alterations.
- Conditions
- Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn, Necrotizing Enterocolitis of Newborn, Neonatal Sepsis, Early-Onset
- Trial name
- AMFIBIE (NCT07152106)
- Where
- 2 sites in Netherlands
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Preterm and Term Infants
fNIRS Grasping Task in Infants
This study aims to investigate the neural mechanisms involved in the development of reach-to-grasp function in infants. Reaching and grasping are crucial motor skills that develop early in infancy and are essential for later…
- Trial name
- NCT07147673
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Ghent
Preterm Birth
Impact of Dietary Sodium Supplementation on Growth & Intestinal Microbiome
The purpose of this project is to determine the direct impact of sodium supplementation in preterm infants and to see the overall improvement of their growth and health status.
- Trial name
- NCT05546814
- Testing
- Sodium algorithm
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Preterm Infant, Breast Feeding
Positive Feeding of the Preterm Infant
The goal of this feasibility study is to assess the feasibility to implement a feeding strategy for preterm infants. The main questions it aims to answer are: Is it feasible to implement the PoP-intervention in a level 3a…
- Conditions
- Preterm Infant, Breast Feeding, Bottle Feeding, Enteral Feeding
- Trial name
- PoP (NCT06189352)
- Testing
- Positive feeding of the preterm infant
- Where
- Norway
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Preterm
Effects of Non-Traumatic Nasopharyngeal Suction Technique in Infants
Background: Non-invasive ventilation (NIV) in preterm infants often leads to secretion-related airway obstructions, requiring suctioning.
- Trial name
- NCT07111611
- Testing
- Non-Traumatic Nasopharyngeal Suction Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Newborn Preterm
The Effect of Bed Head Height During Feeding With Orogastric Catheter on Neonatal Growth
Aim:The study was planned as a randomised controlled experimental study to determine the effect of bed head height applied during feeding with orogastric catheter on growth parameters and feeding tolerance of preterm newborns.
- Trial name
- NCT07079878
- Testing
- Group with Bed Head Height 30°, Group with Bed Head Height 45°
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Preterm Birth, Developmental Dyslexia
Reading-FREE Markers for Early Detection of Developmental Dyslexia
This study aims to identify early signs of developmental dyslexia (DD) and other reading difficulties in children born preterm, using behavioral, cognitive, and brain imaging data collected before reading problems typically…
- Trial name
- FREE-DD (NCT07072104)
- Testing
- Multidomain Neuropsychological and Reading-Free Screening Tool (RSFT) Assessment Battery - Grade 2, MRI - Grade 2, Multidomain Neuropsychological and Reading-Free Screening Tool (RSFT) Assessment Battery - Grade 3
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Pregnancy, Malaria
L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)
There are few safe, effective, and affordable interventions to improve pregnancy outcomes in low resource settings where the highest rates of poor birth outcomes occur.
- Conditions
- Pregnancy, Malaria, Nutrition, Placental Development
- Trial name
- AGREE (NCT05934318)
- Testing
- L-citrulline
- Where
- Kenya
- Volunteers
- 2,960 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Preterm Birth
Exercise in Prematurely Born Preadolescents to Mitigate Cardiovascular Risk and Improve Cognitive Impairment
EXCELSIOR is a randomized controlled trial to investigate the effect of physical exercise on cardiovascular health in prematurely born children.
- Trial name
- EXCELSIOR (NCT06500910)
- Testing
- Physical Exercise
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Henner Hanssen
Osteopathy, PreTerm Neonate
The Effect of Cranial Osteopathy Intervention in Preterm Babies
There are planing to have 2 groups of premature born cases. Each group will include 15 cases. Participants are need to be 28-37 weeks born and no older than post term 6 weeks. All cases are going to be evaluated.
- Conditions
- Osteopathy, PreTerm Neonate, Sensory Profiles, Colic
- Trial name
- NCT06967870
- Testing
- Osteopathic intervention, Home based exercise education
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Preterm Birth, Postpartum Depression
COntact RElationship in Neonatal Intensive Care Unit
The present research project aims to explore the value that contact relationships between caregivers and the preterm infant may have in terms of promoting developmental and maturational processes,by attending to the…
- Trial name
- CORE in NICU (NCT06462638)
- Testing
- Neurobehavioral states and physiological parameters evaluation, Maternal vocal pitch evaluation to assess depressive/anxious state
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Preterm Birth, Pain
Effects of Music Based Intervention (MBI) on Pain Response and Neurodevelopment in Preterm Infants
Pilot prospective randomized, double blinded, controlled study to test effect of music based intervention (MBI) on pain response and neurodevelopment in preterm infants.
- Trial name
- NCT04286269
- Testing
- Music Based Intervention
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Preterm, Breastfeeding
Breastfeeding and Bottle Feeding: Impact on Preterm Infants' Physiology and Feeding Performance
The goal of this clinical trial is to evaluate the effect of breastfeeding on the infant's test weight and physiological characteristics (oxygen saturation and heart rate) in preterm infants in the Neonatal Intensive Care Unit…
- Conditions
- Preterm, Breastfeeding, Bottlefeeding, Premature
- Trial name
- NCT05651035
- Testing
- oral feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Covid19, Pregnancy Related
Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19
Pregnant women are a vulnerable and high-risk population, as COVID-19 is associated with an increased risk preterm birth, cesarean section, and maternal critical care.
- Conditions
- Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus
- Trial name
- STOPCOVID19 (NCT04718220)
- Testing
- Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Malaria, Sexually Transmitted Diseases
Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth
The purpose of this study is to examine whether treatment of pregnant Malawian women with repeated doses of sulfadoxine-pyrimethamine and azithromycin antibiotics will prevent preterm deliveries and result in other health…
- Conditions
- Malaria, Sexually Transmitted Diseases, Preterm Birth, Pregnancy
- Trial name
- NCT00131235
- Testing
- Sulfadoxine-pyrimethamine treatment twice during pregnancy, Sulfadoxine-pyrimethamine at 4-week intervals, Sulfadoxine-pyrimethamine every 4 weeks + azithromycin twice
- Where
- Malawi
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- Tampere University