Clinical trials: Preterm Birth
Premature, Orogastric Tube
Development and Efficiency of Atraumatic Orogastric Tube Insertion Protocol with Combination of Wrapping, Fetal Position, Breastmilk, and Sucrose
This study aimed to reduce the pain and increase comfort during the orogastric tube insertion (OGT) procedure, which is routinely applied to feed these babies at 32-34 weeks of age, in preterm newborns with a sucking reflex.In…
- Conditions
- Premature, Orogastric Tube, Oral Sucrose
- Trial name
- OGT (NCT05180058)
- Testing
- Wrapping + Breastmilk Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ayse Sonay Turkmen, Prof.Dr
Pre-term Birth
fFN Clinical Evaluation in Asymptomatic Women at High Risk for Preterm Birth
This study is designed to determine if quantitative analysis of fetal Fibronectin (fFN) can be used to advance prediction of spontaneous preterm birth (sPTB).
- Trial name
- NCT01955148
- Where
- 16 sites in United States
- Volunteers
- 1,210 people, healthy volunteers welcome
- Sponsor
- Hologic, Inc.
Obstetric Labour, Premature
A Two Cohort Study to Look at the Metabolites of GSK221149, the Metabolism of GSK221149 Administered With a High Fat Meal and With Ketoconazole
This is a two part study. Part A of the study will evaluate the metabolites of GSK221149 following single and repeat oral dosing and will also assess the pharmacokinetics of GSK221149 when administered with a potent CYP3A4…
- Trial name
- NCT01627587
- Testing
- GSK221149 750 mg, Ketoconazole, GSK221149 100 mg
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Bronchopulmonary Dysplasia, Death
Systemic Management in Extremely Preterm and Extremely Low Birth Weight Infants
to estimate incidences of major complications, such as bronchopulmonary dysplasia, death, and delivery room resuscitation among extremely preterm and extremely low birth weight infants in Northern China
- Trial name
- NCT06082414
- Testing
- no interventions
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Peking University
Premature Birth
Family-Centered Intervention for Preterm Children: Effects at School Age and Biosocial Mediators
This study is to extend our previous research to longitudinally examine the effectiveness of intervention programs (FCIP and UCP) for VLBW preterm children in Taiwan at seven years of age.
- Trial name
- NCT03668626
- Testing
- Family-centered intervention program (FCIP)
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Periodontal Disease, Pregnancy
Maternal Periodontal Inflammation and Pregnancy Outcomes: Salivary and Amniotic Biomarkers
Periodontal disease is a chronic inflammatory condition that affects the tissues supporting the teeth and may contribute to systemic inflammation and oxidative stress.
- Conditions
- Periodontal Disease, Pregnancy, Preterm Birth
- Trial name
- NCT07699978
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Discharge Readiness
Using NICU Discharge Education Tools to Enhance Discharge Preparation for Parents of Moderate to Late Preterm Infants
The goal of this clinical trial is to improve the transition to home for preterm infants born between 33-36 weeks gestational age and discharged from the neonatal intensive care unit (NICU) through the use of two interventions, a…
- Trial name
- NCT06177951
- Testing
- NICU Discharge Passport, NICU Infant Care Class
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Preterm Birth, Injuries
Nurse-Family Partnership Impact Evaluation in South Carolina
This study evaluates the effects of the Nurse Family Partnership (NFP), an established home-visiting program, using a scientifically rigorous individual-level randomized controlled trial.
- Conditions
- Preterm Birth, Injuries, Maternal Behavior
- Trial name
- NFP (NCT03360539)
- Testing
- Nurse-Family Partnership
- Where
- 9 sites in United States
- Volunteers
- 5,670 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Pregnancy Preterm, Labor; Irregular
Multichannel EMG Diagnosing True Preterm Labor
We have designed new electromyography sensors for measuring uterine activity. These sensors are directional - they preferentially report uterine muscle contractions at specific locations, called regions.
- Conditions
- Pregnancy Preterm, Labor; Irregular, Preterm Labor
- Trial name
- PTL (NCT03785795)
- Testing
- Uncertain diagnosis of true labor
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- PreTeL, Inc
Macrosomia, Low Birth Weight
Wales Electronic Cohort for Children
The investigators are developing a research platform capable of improving children's health through the generation of knowledge from analysis of routinely collected data from within and outside the health service.
- Conditions
- Macrosomia, Low Birth Weight, Premature Birth, Childhood Obesity
- Trial name
- WECC (NCT01136681)
- Where
- 2 sites in United Kingdom
- Volunteers
- 900,000 people, healthy volunteers welcome
- Sponsor
- Swansea University
Ductus Arteriosus, Patent
Ductus Arteriosus Closure and D-Dimer and Fibrinogen Levels
The aim of this study is to investigate whether there is a relationship between echocardiographic measurements regarding closure of PDA and serum D-Dimer and Fibrinogen levels in premature infants born before 32nd gestational…
- Trial name
- NCT04508036
- Testing
- Withdrawal of blood samples for D-Dimer, Withdrawal of blood samples for Fibrinogen, Echocardiographic Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Preterm Birth, Pregnancy
Psychological Distress & Stress in Parents With Preterm infants-a Prospective Study
The purpose of the present prospective study is the analysis of risk and protective factors of perinatal stress and psychological distress of parents with or without a preterm child.
- Conditions
- Preterm Birth, Pregnancy, Stress, Psychological Distress
- Trial name
- NCT01974531
- Where
- Germany
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Nose Deformities, Acquired
Objectives and Measures Dimensions Nasal Resistance of Preterm and Term (MODERN)
During the resuscitation of preterm infants, withdrawal of non-invasive ventilation is difficult. In a recent study in children gestational age <30 weeks of amenorrhea (SA), definitive withdrawal rate from the first attempt to…
- Trial name
- MODERN (NCT02815345)
- Testing
- Rhinometry
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Respiratory Distress, Transient Tachypnea of the Newborn
Effect of Supine or Prone Position After Caesarean Birth
Respiratory Distress is a frequent clinical diagnosis of babies delivered by elective Caesarean birth. There has been no study comparing the efficacy of immediately positioning a newly born infant prone vs.
- Conditions
- Respiratory Distress, Transient Tachypnea of the Newborn, Delayed Transition of the Newborn, Persistent Pulmonary Hypertension
- Trial name
- NCT01310153
- Testing
- prone positioning, Supine
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Preterm Infants
Socio-Emotional Development in Preterm Infants
With advances in medicine and medical technology, premature infants born as early as 24 weeks of gestation and with birth weight less than 1000 grams are surviving today. Preterms are born with immature biological systems.
- Trial name
- NCT00917475
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Mother-Child Relations, Preterm Birth
The 2015 Pelotas (Brazil) Birth Cohort Study
This is the fourth birth cohort to be carried out in the city of Pelotas (Brazil) including more than 4 thousand children followed-up since the pre-natal period to study maternal-child health.
- Conditions
- Mother-Child Relations, Preterm Birth, Infant Development, Breast Feeding
- Trial name
- NCT03271723
- Testing
- Observational study
- Where
- Brazil
- Volunteers
- 4,275 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Preterm Birth, Activity Restriction
DE-RESTRICT: Deimplementing Activity Restriction for Preterm Birth Prevention
DE-RESTRICT is a pilot study testing whether a strategy to reduce the use of activity restriction and bedrest in pregnancy is acceptable, appropriate, and feasible for prenatal care providers, and whether it changes how often…
- Conditions
- Preterm Birth, Activity Restriction, Bed Rest, Low-Value Care
- Trial name
- NCT07698483
- Testing
- Multicomponent deimplementation strategy
- Where
- 2 sites in United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Neonatal Intensive Care Unit, PreTerm Neonate
Effects of a Structured Maternal Voice Program on Premature Infant Responses and Maternal-Infant Attachment in the Neonatal Intensive Care Unit
This study evaluates the effects of a Structured Maternal Voice Program (SMVP). on premature infant responses and maternal-infant attachment in the intensive care unit (NICU) .
- Conditions
- Neonatal Intensive Care Unit, PreTerm Neonate, Healthy
- Trial name
- SMVP-NICU (NCT06839534)
- Testing
- Structured Maternal Voice Program (SMVP)
- Where
- Thailand
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Preterm Children
Neonatal Cerebral Blood Flow and the Neurobehavioral and Handedness Outcomes in Term and Preterm Adolescents
The results will provide insightful information to understand the process of neural development and the predictive value of early cerebral blood flow measures on longitudinal neurodevelopment and handedness outcomes in preterm…
- Trial name
- NCT04708652
- Testing
- No intervention
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anemia, Neonatal, Necrotizing Enterocolitis
Alteration of Stool Microbiota in Preterm Infants With Anemia
This study evaluates the relationship between anemia and stool microbiota in premature infants. It also evaluates the relationship between blood transfusion and stool microbiota.
- Conditions
- Anemia, Neonatal, Necrotizing Enterocolitis, Dysbiosis
- Trial name
- NCT03554278
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
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