Clinical trials: Preterm Birth
Preterm Premature Rupture of Membranes
Does Vitamins C and E Supplementation of After Preterm Rupture of Membranes Prolong the Duration of Latency? A Prospective Randomized Controlled Study
Preterm premature rupture of membranes (PPROM) is a complication affecting 3-4.5% of all pregnancies. PPROM is the main known cause of preterm delivery and is associated worldwide with increased rates of neonatal and maternal…
- Trial name
- NCT01266928
- Testing
- vitamine C and E
- Where
- Turkey (Türkiye)
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Premature Birth, Bronchopulmonary Dysplasia
Assessment of Lung Structure and Function of Infants Born Prematurely
The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.
- Conditions
- Premature Birth, Bronchopulmonary Dysplasia, Asthma
- Trial name
- NCT00422305
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Indiana University
Neonatal Disease, Neonatal Disorder
Reducing Pain and Promoting Neurodevelopment Among Preterm Neonates
To determine the effects of multisensory stimulation and soft tissue therapy on procedural pain and neurodevelopment among neonates admitted to the NICU is the aim of the study.
- Trial name
- NCT04366102
- Testing
- Multisensory stimulation with soft tissue therapy, Routine hospital care
- Where
- India
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Premature Birth
Association Between Mother-Infant Attunement During Interaction and the Quality of General Movements
The proposed research has the potential of contributing to the limited empirical literature on the relationship between maternal sensitivity and motor development of preterm infants.
- Trial name
- NCT01764958
- Where
- Israel
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Assuta Hospital Systems
Premature Birth, Premature Infant
The Effects Of Auditory Interventions On Pain And Comfort In Premature Infants
This study investigated the effects of three interventions -recorded mother's voice, white noise, and MiniMuffs, muffs used to attenuate environmental sounds- applied during a heel lance on pain and comfort in premature infants.
- Trial name
- NCT04067206
- Testing
- RECORDED MOTHER'S VOICE, White Noise, MiniMuff
- Where
- Turkey (Türkiye)
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Ege University
Infectious Diseases
Prevention of Necrotizing Enterocolitis of Premature Newborns Under Less Than 1500 g Using Probiotics
The purpose of this study is to evaluate the incidence of necrotizing enterocolitis and its effect over the secreting immunoglobulin A in the feces with the use of probiotics of the strain Lactobacillus acidophilus boucardii vs.
- Trial name
- (PEPP) (NCT02245815)
- Testing
- use probiotics boucardii, use probiotics Multi-species
- Where
- Mexico
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Preterm Premature Rupture of the Membranes
Transperineal Ultrasonography and Premature Rupture of Membranes
This study's aim is to evaluate diagnostic accuracy of transperineal ultrasound assessment compared with speculum examination, nitrazine and placental micro globulin-1 tests.
- Trial name
- NCT02386644
- Testing
- PAMG-1 Immunoassay, Ultrasound transperineal assessment, Ultrasound amniotic fluid index measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Ankara University
Preterm Premature Rupture of Membranes
Magnesium Sulfate Versus Placebo for Tocolysis in PPROM
Study compares the outcomes of women between 26 and 32 wks gestation with rupture of membranes. Women randomized to receive tocolysis with magnesium sulfate x 48 hrs or placebo of saline IV x 48 hrs.
- Trial name
- NCT00463736
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Regional Obstetrical Consultants
Preterm
Effects of Non-Traumatic Nasopharyngeal Suction Technique in Infants
Background: Non-invasive ventilation (NIV) in preterm infants often leads to secretion-related airway obstructions, requiring suctioning.
- Trial name
- NCT07111611
- Testing
- Non-Traumatic Nasopharyngeal Suction Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Healthy Volunteers
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors…
- Trial name
- NCT04286464
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
PreTerm Neonate
Effect of Nursing Interventions on Pain and Salivary Cortisol Levels During Heel Stick in Preterm Newborns
Babies born before the thirty-seventh gestational week are called preterm or premature. Most preterm newborns require Neonatal Intensive Care Unit (NICU) care depending on their gestational age and clinical condition.
- Trial name
- NCT06628232
- Testing
- pacifier with breast milk, heel heating, interventions combined
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Healthy Children, Preterm Birth
Executive Training and Brain in Children
The purpose of this study is to determine whether a daily executive training to cognitive inhibition, working memory or mindfulness as compared to an active control condition has a near- and far-transfer impact on brain and…
- Trial name
- APEX (NCT02989116)
- Testing
- Inhibition training, Working memory training, Mindfulness training
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Premature
Pain and Comfort During Endotracheal Suction in Premature Neonates
Most of the preterm babies in neonatal units are followed up with invasive mechanical ventilation support. For this reason, endotracheal suction is needed repeatedly in preterm babies in order to open the airway obstruction…
- Trial name
- NCT05095285
- Testing
- Swaddling, Oropharyngeal colostrum
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Preterm Labor
Study on Prevention, Treatment and Mechanism of Preterm Labor for Chinese Pregnant Women ≥35 Years Old
In China, there's no effective prevention and treatment on preterm birth for pregnant women ≥35 years old, so this study is necessary.
- Trial name
- NCT03210415
- Testing
- Observational Study Model
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Premature Birth
Cerebral Blood Flow Parameters and Neurobehavioral Development in Infants at Term Age
Although several studies have contrasted the hemodynamics of cerebral arteries using cranial Doppler ultrasound between full-term and preterm infants, the assessments were mostly conducted in the first days of life.
- Trial name
- NCT00676247
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Retinopathy of Prematurity
Oral Propranolol Improve Retinopathy of Prematurity Outcomes in Very Preterm Infants
Retinopathy of prematurity (ROP) is a major cause of blindness and visual impairment in children in both developing and developed countries around the world.
- Trial name
- NCT02977000
- Testing
- Propranolol
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Huiqing Sun
Cerebral Palsy, Developmental Coordination Disorder
The Relationship Between Developmental Level in Infancy and Preschool Motor Performance in Risky Infants
The primary purpose of this study is to evaluate the relationship between the developmental level between 1-18 months and gross motor performance in the preschool period in risky infants followed up from a center for early…
- Trial name
- NCT06015347
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Marmara University
Prematurity, High Risk Pregnancy
Prematurity Education in High Risk Pregnancies
Prematurity is associated with significant morbidity and mortality. Given the high risk of death and disability, it is important for parents to understand the complications of prematurity so they can make decisions for their…
- Trial name
- NCT03772080
- Testing
- Early counseling of prematurity in high-risk pregnancies.
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Preterm Infants
Executive Function in Preterm Born Children: An Integrative Approach From Genetics to Brain Function
Hd-EEG and MRI measures are used to study the maturation of functional networks in order to identify the neural circuits underlying executive and memory processes in children born preterm.
- Trial name
- NCT01615523
- Testing
- MRI, EEG and cognitive testing
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Nursing Caries
Nursing Care in Threat of Preterm Birth
Relaxation-Focused Nursing Care which is formed by using these two models is composed of; positive language, positive environment and reducing stressors.
- Trial name
- NCT04045197
- Testing
- Relaxation Focused Nursing Care
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hülya Özberk
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